Fred Hutchinson Cancer Research Center
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Fred Hutchinson Cancer Research Center
The Fred Hutchinson Cancer Center, formerly known as the Fred Hutchinson Cancer Research Center and also known as Fred Hutch or The Hutch, is a cancer research institute established in 1975 in Seattle, Washington. History The center grew out of the Pacific Northwest Research Foundation, founded in 1956 by William B. Hutchinson (1909–1997). The Foundation was dedicated to the study of heart surgery, cancer, and diseases of the endocrine system. Hutchinson's younger brother Fred (1919–1964) was a major league pitcher and manager who died of lung cancer at age 45. The next year, William Hutchinson established the Fred Hutchinson Cancer Research Center as a division of the Pacific Northwest Research Foundation.Louis Fiset, December 30, 2004 for HistoryLink: The Free, Online Encyclopedia of Washington State HistorHutchinson, Dr. William B. (1909-1997)/ref> In 1972, with the help of Senator Warren G. Magnuson, PNRF received federal funding under the National Cancer Act of 19 ...
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Nonprofit Organization
A nonprofit organization (NPO) or non-profit organisation, also known as a non-business entity, not-for-profit organization, or nonprofit institution, is a legal entity organized and operated for a collective, public or social benefit, in contrast with an entity that operates as a business aiming to generate a Profit (accounting), profit for its owners. A nonprofit is subject to the non-distribution constraint: any revenues that exceed expenses must be committed to the organization's purpose, not taken by private parties. An array of organizations are nonprofit, including some political organizations, schools, business associations, churches, social clubs, and consumer cooperatives. Nonprofit entities may seek approval from governments to be Tax exemption, tax-exempt, and some may also qualify to receive tax-deductible contributions, but an entity may incorporate as a nonprofit entity without securing tax-exempt status. Key aspects of nonprofits are accountability, trustworth ...
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National Cancer Act Of 1971
The "war on cancer" is the effort to find a cure for cancer by increased research to improve the understanding of cancer biology and the development of more effective cancer treatments, such as targeted drug therapies. The aim of such efforts is to eradicate cancer as a major cause of death. The signing of the National Cancer Act of 1971 by United States president Richard Nixon is generally viewed as the beginning of this effort, though it was not described as a "war" in the legislation itself. Despite significant progress in the treatment of certain forms of cancer (such as childhood leukemia), cancer in general remains a major cause of death half a century after this war on cancer began, leading to a perceived lack of progress and to new legislation aimed at augmenting the original National Cancer Act of 1971. New research directions, in part based on the results of the Human Genome Project, hold promise for a better understanding of the genetic factors underlying cancer, and th ...
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Leland H
Leland may refer to: Places United States * Leland, Illinois, a village * Leland, Iowa, a city * Leland, Michigan, an unincorporated community and census-designated place * Leland, Mississippi, a city * Leland, North Carolina, a town * Leland, Oregon, an unincorporated community * Leland, Utah, an unincorporated community * Leland, Washington, an unincorporated community * Leland, Wisconsin, an unincorporated community * Leland Township, Michigan * Leland River, Michigan * Leland Pond, New York Elsewhere * Leland, Norway, a village * Mount Leland, Victoria Land, Antarctica People Given name * Leland Austin (born 1986), American rapper under the stage name Yung L.A. * Leland Bardwell (1922–2016), Irish poet, novelist and playwright * Leland Chapman Leland Blane Chapman (born December 14, 1976) is an American bail bondsman and bounty hunter, known as one of the stars of the A&E Network reality television program '' Dog the Bounty Hunter''. He also starred in the Countr ...
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Bone Marrow Transplantation
Hematopoietic stem-cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood in order to replicate inside of a patient and to produce additional normal blood cells. It may be autologous (the patient's own stem cells are used), allogeneic (the stem cells come from a donor) or syngeneic (from an identical twin). It is most often performed for patients with certain cancers of the blood or bone marrow, such as multiple myeloma or leukemia. In these cases, the recipient's immune system is usually destroyed with radiation or chemotherapy before the transplantation. Infection and graft-versus-host disease are major complications of allogeneic HSCT. HSCT remains a dangerous procedure with many possible complications; it is reserved for patients with life-threatening diseases. As survival following the procedure has increased, its use has expanded beyond cancer to autoimm ...
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Olfactory System
The olfactory system, or sense of smell, is the sensory system used for smelling (olfaction). Olfaction is one of the special senses, that have directly associated specific organs. Most mammals and reptiles have a main olfactory system and an accessory olfactory system. The main olfactory system detects airborne substances, while the accessory system senses fluid-phase stimuli. The senses of smell and taste (gustatory system) are often referred to together as the chemosensory system, because they both give the brain information about the chemical composition of objects through a process called transduction. Structure Peripheral The peripheral olfactory system consists mainly of the nostrils, ethmoid bone, nasal cavity, and the olfactory epithelium (layers of thin tissue covered in mucus that line the nasal cavity). The primary components of the layers of epithelial tissue are the mucous membranes, olfactory glands, olfactory neurons, and nerve fibers of the olfactory nerves. ...
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Linda B
Linda may refer to: As a name * Linda (given name), a female given name (including a list of people and fictional characters so named) * Linda (singer) (born 1977), stage name of Svetlana Geiman, a Russian singer * Anita Linda (born Alice Lake in 1924), Filipino film actress * Bogusław Linda (born 1952), Polish actor * Solomon Linda (1909–1962), South African Zulu musician, singer and composer who wrote the song "Mbube" which later became "The Lion Sleeps Tonight" Places * Linda, California, a census-designated place * Linda, Missouri, a ghost town * Linda, Tasmania, Australia, a ghost town * Linda, Georgia, village in Abkhazia, Georgia * Linda, Bashkortostan, village in Bashkortostan, Russia * Linda Valley, Tasmania * 7169 Linda, an asteroid * Linda, a small lunar crater - see Delisle (crater) Music * ''Linda'' (Linda George album), 1974 * ''Linda'' (Linda Clifford album), 1977 * ''Linda'' (Miguel Bosé album), 1978 ** "Linda" (Miguel Bosé song), the title song * ...
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Nobel Prize In Physiology Or Medicine
The Nobel Prize in Physiology or Medicine is awarded yearly by the Nobel Assembly at the Karolinska Institute for outstanding discoveries in physiology or medicine. The Nobel Prize is not a single prize, but five separate prizes that, according to Alfred Nobel's 1895 will, are awarded "to those who, during the preceding year, have conferred the greatest benefit to humankind". Nobel Prizes are awarded in the fields of Physics, Chemistry, Physiology or Medicine, Literature, and Peace. The Nobel Prize is presented annually on the anniversary of Alfred Nobel's death, 10 December. As of 2022, 114 Nobel Prizes in Physiology or Medicine have been awarded to 226 laureates, 214 men and 12 women. The first one was awarded in 1901 to the German physiologist, Emil von Behring, for his work on serum therapy and the development of a vaccine against diphtheria. The first woman to receive the Nobel Prize in Physiology or Medicine, Gerty Cori, received it in 1947 for her role in elucidati ...
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Lee Hartwell
Leland Harrison (Lee) Hartwell (born October 30, 1939 in Los Angeles, California) is former president and director of the Fred Hutchinson Cancer Research Center in Seattle, Washington (state), Washington. He shared the 2001 Nobel Prize in Physiology or Medicine with Paul Nurse and Tim Hunt, for their discoveries of protein molecules that control the division (duplication) of cells. Working in yeast, Hartwell identified the fundamental role of checkpoints in cell cycle control, and CDC genes such as CDC28, which controls the start of the cycle—the progression through G1. Education Hartwell attended Glendale High School (Glendale, California), Glendale High School in Glendale, California, and then received his Bachelor of Science from the California Institute of Technology in 1961. In 1964, he received his Doctor of Philosophy in biology from the Massachusetts Institute of Technology. From 1965 to 1968, he worked at the University of California, Irvine as a professor. He moved t ...
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Lawrence Corey
Research and career In the early 1980s, Corey worked with Nobel Prize-winning biochemist and pharmacologist Dr. Gertrude Elion to demonstrate that an antiviral that was selective and specific for a viral-specified enzyme could be safely and effectively administered to control a chronic viral infection (herpes simplex virus type 2 or HSV-2). Corey first conceived of and demonstrated the core concepts and direct line association between quantitative viral load reduction and clinical benefit using topical, intravenous and oral formulations of acyclovir in classic studies performed between 1980 and 1984. Acyclovir was the first antiviral drug to get rapid approval from the FDA, and it was Corey's studies that defined its use in genital herpes. These studies led to the licensure for acyclovir in a wide variety of infections such as HSV-1, HSV-2 and varicella chickenpox virus, including the first use of an antiviral for daily long term use. Acyclovir and its derivatives valacyclovir and f ...
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The Seattle Times
''The Seattle Times'' is a daily newspaper serving Seattle, Washington, United States. It was founded in 1891 and has been owned by the Blethen family since 1896. ''The Seattle Times'' has the largest circulation of any newspaper in Washington (state), Washington state and the Pacific Northwest region. The Seattle Times Company, which is owned by the Blethen family, holds 50.5% of the paper. McClatchy company owns 49.5% of the paper. ''The Seattle Times'' had a longstanding rivalry with the ''Seattle Post-Intelligencer'' newspaper until the latter ceased publication in 2009. Copies are sold at $2 daily in King & adjacent counties (except Island, Thurston & other WA counties, $2.5) or $3 Sundays/Thanksgiving Day (except Island, Thurston & other WA counties, $4). Prices are higher outside Washington state. History ''The Seattle Times'' originated as the ''Seattle Press-Times'', a four-page newspaper founded in 1891 with a daily Newspaper circulation, circulation of 3,500, which M ...
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Seattle Children's
Seattle Children's, formerly Children's Hospital and Regional Medical Center, formerly Children's Orthopedic Hospital, is a children's hospital in the Laurelhurst neighborhood of Seattle, Washington. The hospital specializes in the care of infants, children, teens, and young adults aged 0–21 in several specialties. History The hospital was founded as the seven-bed Children's Orthopedic Hospital in 1907 by Anna Herr Clise after her 5-year-old son, Willis, died of inflammatory rheumatism in 1898. It was originally a ward of the downtown Seattle General Hospital. It moved to a cottage on Queen Anne Hill the next year, and in 1911 influential community members including Herbert Gowen and Mark A. Matthews dedicated a full 40-bed hospital at the same location. The library at the hospital was founded in 1946. In 1953, Children's moved to a new campus in Laurelhurst, east of the University of Washington. A research division, Seattle Children's Research Institute (SCRI), was es ...
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