Biflavonoids are a type of
flavonoids with the general formula scheme (C6-C3-C6)
2.
Examples
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Amentoflavone
Amentoflavone is a biflavonoid (''bis''-apigenin coupled at 8 and 3' positions, or 3′,8′′-biapigenin) constituent of a number of plants including ''Ginkgo biloba'', ''Chamaecyparis obtusa'' (hinoki), '' Hypericum perforatum'' (St ...
(bis-apigenin coupled at 8 and 3' positions)
*
Lophirone L and
lophirone M found in ''
Lophira alata
''Lophira alata'', commonly known as azobé, ekki or the red ironwood tree, is a species of plant in the family Ochnaceae. It is found in Cameroon, the Republic of the Congo, the Democratic Republic of the Congo, Ivory Coast, Equatorial Guinea, G ...
''
*
Sulcatone A, a naturally occurring biflavonoid isolated from ''
Ouratea sulcata''. Extracts of the leaves of this plant, used with and with other plant's extracts, are used in many African countries to treat some infections such as upper tract respiratory infections, dysenteria, diarrhoea and toothache. Positive antimicrobial activity has been shown in-vitro against ''
Staphylococcus aureus'' and ''
Bacillus subtilis
''Bacillus subtilis'', known also as the hay bacillus or grass bacillus, is a Gram-positive, catalase-positive bacterium, found in soil and the gastrointestinal tract of ruminants, humans and marine sponges. As a member of the genus ''Bacillus ...
''. ''
Escherichia coli
''Escherichia coli'' (),Wells, J. C. (2000) Longman Pronunciation Dictionary. Harlow ngland Pearson Education Ltd. also known as ''E. coli'' (), is a Gram-negative, facultative anaerobic, rod-shaped, coliform bacterium of the genus '' Esc ...
'' showed to be resistant in the same study.
*
Hinokiflavone, a cytotoxic biflavonoid from ''
Toxicodendron succedaneum
''Toxicodendron succedaneum'', the wax tree, Japanese Hazenoki tree (Sumac or wax tree), sơn in Vietnam or charão in Portuguese, is a flowering plant species in the genus '' Toxicodendron'' found in Asia, although it has been planted elsewhere ...
'', ''
Juniperus
Junipers are coniferous trees and shrubs in the genus ''Juniperus'' () of the cypress family Cupressaceae. Depending on the taxonomy, between 50 and 67 species of junipers are widely distributed throughout the Northern Hemisphere, from the Arcti ...
sp.'', or ''
Chamaecyparis obtusa'' (hinoki).
* Leaflets of ''
Cycas circinalis
''Cycas circinalis'', also known as the queen sago, is a species of cycad known in the wild only from southern India. ''Cycas circinalis'' is the only gymnosperm species found among native Sri Lankan flora.
Taxonomy
''C. circinallis'' is native ...
'' and ''
C. revoluta'' contain biflavonoids such as (2''S'', 2′′''S'')-2,3,2′′,3′′-tetrahydro-4′,4′′′-di-''O''-methylamentoflavone (
tetrahydroisoginkgetin).
*
Agathisflavone
*
Cupressuflavone
*
Ginkgetin
*
Morelloflavone
Morelloflavone, an isolate of ''Garcinia dulcis'', belongs to the family of biflavonoids and is an inhibitor of HMG-CoA reductase
HMG-CoA reductase (3-hydroxy-3-methyl-glutaryl-coenzyme A reductase, official symbol HMGCR) is the rate-control ...
*
Neorhusflavanone
*
Ochnaflavone
Ochnaflavone, a secondary plant secondary metabolite of the Biflavonoid family, has been widely investigated in past decades due to its unique ability to mediate biological activities, such as inhibition of phospholipase A2 and lymphocyte prolifer ...
*
Podocarpusflavone A
*
Rhusflavone
*
Rhusflavanone
*
Robustaflavone
*
Sciadopitysin
*
Spicataside
*
Succedaneaflavanone
*
Volkensiflavone
*
Moghatin, extracted from ''
Glossostemon bruguieri''
References
Flavonoids
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