Allison McGeer
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Allison Joan McGeer (born 1953) is a Canadian infectious disease specialist in the
Sinai Health System The Sinai Health is a hospital system which serves Toronto, Ontario, Canada. It comprises two hospitals, Mount Sinai Hospital (an acute care hospital) and Hennick Bridgepoint Hospital, formally Bridgepoint Active Healthcare (a rehabilitation ho ...
, and a professor in th
Department of Laboratory Medicine and Pathobiology
at the University of Toronto. She also appointed at the
Dalla Lana School of Public Health Dalla Lana School of Public Health is the school of public health at the University of Toronto. It was founded in 1927, and was home for 50 years to Connaught Laboratories, a manufacturer of vaccines, insulin, and many other pharmaceutical produc ...
and a Senior Clinician Scientist at the
Lunenfeld-Tanenbaum Research Institute The Lunenfeld-Tanenbaum Research Institute is a medical research institute in Toronto, Ontario and part of the Sinai Health System. It was originally established in 1985 as the Samuel Lunenfeld Research Institute, the research arm of Mount Si ...
, and is a partner of the
National Collaborating Centre for Infectious Diseases The National Collaborating Centre for Infectious Diseases, formerly The International Centre for Infectious Disease (ICID) is a Canadian organisation set up in 2004 to collaborate resources worldwide in the fight against infectious diseases. Purpo ...
. McGeer has led investigations into the
severe acute respiratory syndrome Severe acute respiratory syndrome (SARS) is a viral respiratory disease of zoonotic origin caused by the severe acute respiratory syndrome coronavirus (SARS-CoV or SARS-CoV-1), the first identified strain of the SARS coronavirus species, ''sev ...
outbreak in
Toronto Toronto ( ; or ) is the capital city of the Canadian province of Ontario. With a recorded population of 2,794,356 in 2021, it is the most populous city in Canada and the fourth most populous city in North America. The city is the anch ...
and worked alongside
Donald Low Donald Low (May 2, 1945 - September 18, 2013) was a Canadian microbiologist noted for his role in battling the SARS outbreak of 2003. He was microbiologist-in-chief at Mount Sinai Hospital, Toronto, from 1985 to 2013. Low graduated from medical s ...
. During the
COVID-19 pandemic The COVID-19 pandemic, also known as the coronavirus pandemic, is an ongoing global pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The novel virus was first identi ...
, McGeer has studied how
SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) is a strain of coronavirus that causes COVID-19 (coronavirus disease 2019), the respiratory illness responsible for the ongoing COVID-19 pandemic. The virus previously had a ...
survives in the air and has served on several provincial committees advising aspects of the
Government of Ontario The government of Ontario (french: Gouvernement de l'Ontario) is the body responsible for the administration of the Canadian province of Ontario. A constitutional monarchy, the Crown—represented in the province by the lieutenant governorâ ...
's pandemic response.


Early life and education

In 1974, McGeer earned a B.Sc. in biochemistry from the
University of Toronto The University of Toronto (UToronto or U of T) is a public university, public research university in Toronto, Ontario, Canada, located on the grounds that surround Queen's Park (Toronto), Queen's Park. It was founded by royal charter in 1827 ...
. She earned a master's degree and then an M.D. in 1982. She trained in internal medicine and infectious diseases at the University of Toronto. From 1989 to 1990, McGeer was a clinical fellow in hospital
epidemiology Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and determinants of health and disease conditions in a defined population. It is a cornerstone of public health, and shapes policy decisions and evide ...
at
Yale New Haven Hospital Yale New Haven Hospital (YNHH) is a 1,541-bed hospital located in New Haven, Connecticut. It is owned and operated by the Yale New Haven Health System. YNHH includes the 168-bed Smilow Cancer Hospital at Yale New Haven, the 201-bed Yale New Haven ...
.


Career

In 1989, McGeer joined the
Sinai Health System The Sinai Health is a hospital system which serves Toronto, Ontario, Canada. It comprises two hospitals, Mount Sinai Hospital (an acute care hospital) and Hennick Bridgepoint Hospital, formally Bridgepoint Active Healthcare (a rehabilitation ho ...
, where she specialised in microbiology. She holds a joint position as Professor in th
Department of Laboratory Medicine and Pathobiology
and of Infectious Diseases at the
Dalla Lana School of Public Health Dalla Lana School of Public Health is the school of public health at the University of Toronto. It was founded in 1927, and was home for 50 years to Connaught Laboratories, a manufacturer of vaccines, insulin, and many other pharmaceutical produc ...
. At the University of Toronto, she has focussed on developing mechanisms to stop the spread of infectious diseases in hospitals and care homes. McGeer has studied the impact of influenza on hospital staff. She encouraged people of all ages to receive the
universal flu vaccine A universal flu vaccine is a flu vaccine that is effective against all influenza strains regardless of the virus sub type, antigenic drift or antigenic shift.Sherwood Linda M, Prescott's Microbiology (10th ed.) McGraw-Hill Education , 2017 Henc ...
and supported hospitals in improving their influenza testing. She also contributed to a review of influenza diagnosis among older hospitalized patients on behalf of the Canadian Immunization Research Network (CIRN) Serious Outcomes Surveillance (SOS) Network. She is the director of infection control, and works as a microbiologist and infectious disease consultant at the Mount Sinai Hospital. Her staff directory page acknowledges funding through an unrestricted educational grant from
Pfizer Canada Pfizer Inc. ( ) is an American Multinational corporation, multinational Pharmaceutical industry, pharmaceutical and biotechnology corporation headquartered on 42nd Street (Manhattan), 42nd Street in Manhattan, Manhattan, New York City. The co ...
. McGeer studies the prevention and management of bacterial and viral infections. Her primary areas of research interest are the prevention of healthcare associated infection, the epidemiology of influenza, and adult immunization. She has received research grants from
Pfizer Pfizer Inc. ( ) is an American multinational pharmaceutical and biotechnology corporation headquartered on 42nd Street in Manhattan, New York City. The company was established in 1849 in New York by two German entrepreneurs, Charles Pfizer ...
and Seqirus, as well as personal and consulting fees from
AstraZeneca AstraZeneca plc () is a British-Swedish multinational pharmaceutical and biotechnology company with its headquarters at the Cambridge Biomedical Campus in Cambridge, England. It has a portfolio of products for major diseases in areas includi ...
, GlaxoSmithKline, Janssen, Medicago,
Merck Merck refers primarily to the German Merck family and three companies founded by the family, including: * the Merck Group, a German chemical, pharmaceutical and life sciences company founded in 1668 ** Merck Serono (known as EMD Serono in the Unite ...
,
Moderna Moderna, Inc. ( ) is an American pharmaceutical and biotechnology company based in Cambridge, Massachusetts that focuses on RNA therapeutics, primarily mRNA vaccines. These vaccines use a copy of a molecule called messenger RNA (mRNA) to pro ...
, and
Sanofi Pasteur Sanofi Pasteur is the vaccines division of the French multinational pharmaceutical company Sanofi. Sanofi Pasteur is the largest company in the world devoted entirely to vaccines. It is one of four global producers of the yellow fever vaccine. ...
.


SARS and MERS

McGeer led the investigations into
Severe Acute Respiratory Syndrome Severe acute respiratory syndrome (SARS) is a viral respiratory disease of zoonotic origin caused by the severe acute respiratory syndrome coronavirus (SARS-CoV or SARS-CoV-1), the first identified strain of the SARS coronavirus species, ''sev ...
(SARS) in Toronto. She was based at the
Ontario Ontario ( ; ) is one of the thirteen provinces and territories of Canada.Ontario is located in the geographic eastern half of Canada, but it has historically and politically been considered to be part of Central Canada. Located in Central C ...
SARS emergency operation centre. At the time, she contracted the disease, and accidentally exposed several other health officials to the disease. The health officials were quarantined and did not develop the disease. The
basic reproduction number In epidemiology, the basic reproduction number, or basic reproductive number (sometimes called basic reproduction ratio or basic reproductive rate), denoted R_0 (pronounced ''R nought'' or ''R zero''), of an infection is the expected number of ...
of severe acute respiratory syndrome-related coronavirus (SARS-CoV) was between 2.2 and 3.7, but super-spreading events (highly efficient transmission of the virus) occurred in some hospital settings. McGeer believes that Toronto eliminated SARS by isolating people who were infected or at risk from the virus, preventing its spread. A study the critical care units of Toronto's hospitals found that the consistent use of
N95 mask An N95 filtering facepiece respirator, commonly abbreviated N95 respirator, is a particulate-filtering facepiece respirator that meets the U.S. National Institute for Occupational Safety and Health (NIOSH) N95 classification of air filtratio ...
s was an effective way to protect nurses. During the 2013 MERS outbreak, McGeer visited
Saudi Arabia Saudi Arabia, officially the Kingdom of Saudi Arabia (KSA), is a country in Western Asia. It covers the bulk of the Arabian Peninsula, and has a land area of about , making it the fifth-largest country in Asia, the second-largest in the A ...
with the
World Health Organization The World Health Organization (WHO) is a specialized agency of the United Nations responsible for international public health. The WHO Constitution states its main objective as "the attainment by all peoples of the highest possible level of ...
to help to track the spread of the virus. Through careful monitoring of the air, food and water supply, McGeer helped to control the spread of the virus.


COVID-19 pandemic

Throughout the
COVID-19 pandemic The COVID-19 pandemic, also known as the coronavirus pandemic, is an ongoing global pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The novel virus was first identi ...
McGeer provided health advice to the Canadian public, including as a member of the
Ontario COVID-19 Science Advisory Table The Ontario COVID-19 Science Advisory Table, often referred to simply as the Ontario Science Table (OST), was a group of independent scientific experts that provided advice to the Government of Ontario about COVID-19. It consisted of several s ...
. She also serves on Canada's COVID-19 Expert Panel, assembled by Chief Science Advisor of Canada Dr.
Mona Nemer Mona Nemer, (born 1957) is a Lebanese-Canadian scientist specializing in molecular genetics and cardiac regeneration. She was formerly a professor of pharmacology at the University of Montreal and the Director of the Cardiac Development Researc ...
to assist in providing advice and guidance to
Prime Minister Justin Trudeau Justin Pierre James Trudeau ( , ; born December 25, 1971) is a Canadian politician who is the 23rd and current prime minister of Canada. He has served as the prime minister of Canada since 2015 and as the leader of the Liberal Party since 20 ...
and the federal government. In late January 2020, McGeer expressed concerns over the ability to contain
SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) is a strain of coronavirus that causes COVID-19 (coronavirus disease 2019), the respiratory illness responsible for the ongoing COVID-19 pandemic. The virus previously had a ...
, particularly the unknown
incubation period Incubation period (also known as the latent period or latency period) is the time elapsed between exposure to a pathogenic organism, a chemical, or radiation, and when symptoms and signs are first apparent. In a typical infectious disease, the in ...
, which makes it difficult to track and quarantine people who have been exposed. In early March she emphasized the need for Canadians to follow
public health Public health is "the science and art of preventing disease, prolonging life and promoting health through the organized efforts and informed choices of society, organizations, public and private, communities and individuals". Analyzing the det ...
advice to prevent the widespread transmission of SARS-CoV-2. According to McGeer, the most important guidance was to limit social contact and stay at home when feeling unwell. McGeer started to investigate how long SARS-CoV-2 can survive in air in March 2020. She was interested in how exhaled droplets, which contain both water and the virus, may become an infective aerosol that is light enough to be transported by air currents. Caroline Duchaine, an aerosol specialist at the
Université Laval Université Laval is a public research university in Quebec City, Quebec, Canada. The university was founded by royal charter issued by Queen Victoria in 1852, with roots in the founding of the Séminaire de Québec in 1663 by François de Montm ...
, thinks that the virus may not be as potent in aerosol form, losing parts of its spiky protein shell as it dries out in the air. McGeer and Duchaine are interested in how the virus survives in air in a hospital setting, particularly around patients who are being intubated. She hopes her research will provide insight as to whether face masks should be worn to reduce the transmission of the virus. At the time, the
Centers for Disease Control and Prevention The Centers for Disease Control and Prevention (CDC) is the national public health agency of the United States. It is a United States federal agency, under the Department of Health and Human Services, and is headquartered in Atlanta, Georgi ...
were considering whether to advise members of the public to wear masks when they left the house, and they had been made mandatory in the
Czech Republic The Czech Republic, or simply Czechia, is a landlocked country in Central Europe. Historically known as Bohemia, it is bordered by Austria to the south, Germany to the west, Poland to the northeast, and Slovakia to the southeast. The ...
. In her role at Mount Sinai Hospital, McGeer acted as a local
principal investigator In many countries, the term principal investigator (PI) refers to the holder of an independent grant and the lead researcher for the grant project, usually in the sciences, such as a laboratory study or a clinical trial. The phrase is also often us ...
for the "CONvalescent Plasma for Hospitalized Adults With COVID-19 Respiratory Illness" (CONCOR-1) study. She also served as a principal investigator on a study examining the association between frailty and outcomes of
COVID-19 Coronavirus disease 2019 (COVID-19) is a contagious disease caused by a virus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first known case was identified in Wuhan, China, in December 2019. The disease quickly ...
infection. In May 2021, McGeer explained that
National Advisory Committee on Immunization The National Advisory Committee on Immunization (NACI; french: Comité consultatif national de l'immunisation; french: CCNI, label=none) is an advisory body that provides the Government of Canada with medical and scientific advice relating to h ...
(NACI) deliberations to approve COVID-19 vaccines couldn't be made available to the public because the agency "has nothing like the budget or staff that would be needed" to do so. While NACI is mandated to "gather and evaluate the available data relevant to vaccines," McGeer also noted "they are not adequately resourced for rapid and comprehensive scientific assessment." She welcomed NACI's September 2021 recommendation of a COVID-19 vaccine booster shot for residents of long-term and congregate care facilities, citing evidence of waning immunity among this population. McGeer was recruited as a member of the newly formed Ontario Immunization Advisory Committee (OIAC), created by Chief Medical Officer of Health
Kieran Moore Kieran Michael Moore is a Canadian physician and public servant who serves as the current chief medical officer of health of Ontario. Prior to his appointment, he served as the medical officer of health for Kingston, Frontenac, Lennox and Add ...
in August 2021 to work on provincial vaccine programs (including for
COVID-19 Coronavirus disease 2019 (COVID-19) is a contagious disease caused by a virus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first known case was identified in Wuhan, China, in December 2019. The disease quickly ...
).


Membership

* Canada's COVID-19 Expert Panel * Canada's Expert Advisory Group on Antimicrobial Resistance (EAGAR) * Canada's
National Advisory Committee on Immunization The National Advisory Committee on Immunization (NACI; french: Comité consultatif national de l'immunisation; french: CCNI, label=none) is an advisory body that provides the Government of Canada with medical and scientific advice relating to h ...
*
National Collaborating Centre for Infectious Diseases The National Collaborating Centre for Infectious Diseases, formerly The International Centre for Infectious Disease (ICID) is a Canadian organisation set up in 2004 to collaborate resources worldwide in the fight against infectious diseases. Purpo ...
, partner *
Ontario COVID-19 Science Advisory Table The Ontario COVID-19 Science Advisory Table, often referred to simply as the Ontario Science Table (OST), was a group of independent scientific experts that provided advice to the Government of Ontario about COVID-19. It consisted of several s ...
* Ontario Immunization Advisory Committee * Ontario Provincial Infectious Diseases Advisory Committee, infection control subcommittee, member


Awards

* 2014: ''
Toronto Life ''Toronto Life'' is a monthly magazine about entertainment, politics and life in Toronto, Ontario, Canada. ''Toronto Life'' also publishes a number of annual special interest guides about the city, including ''Real Estate'', ''Stylebook'', ''Eatin ...
'', Toronto's 30 Best Doctors * 2015: Canadian Medical Association, May Cohen Award for Women Mentors * 2016:
Association of Medical Microbiology and Infectious Disease Canada The Association of Medical Microbiology and Infectious Disease Canada (AMMI Canada) is a Canadian national medical specialty association composed of specialists in infectious diseases and medical microbiology, clinical microbiologists and research ...
, Lifetime Achievement Award * 2021:
University of Toronto Faculty of Medicine The Temerty Faculty of Medicine (previously Faculty of Medicine) is the medical school of the University of Toronto. Founded in 1843, the faculty is based in Downtown Toronto and is one of Canada's oldest institutions of medical studies, being k ...
, Norman Rosenblum Award for Excellence in Mentorship in the MD/PhD Program * 2021: Canadian Association for Clinical Microbiology and Infectious Diseases, John G. FitzGerald – CACMID Outstanding Microbiologist Award


Selected works and publications

* * * * *


References


External links


Allison McGeer, M.D., FRCPC
at Mount Sinai Hospital
Allison McGeer
at th
Department of Laboratory Medicine and Pathobiology

Allison McGeer
at
Dalla Lana School of Public Health Dalla Lana School of Public Health is the school of public health at the University of Toronto. It was founded in 1927, and was home for 50 years to Connaught Laboratories, a manufacturer of vaccines, insulin, and many other pharmaceutical produc ...

Dr. Allison McGeer
at
Lunenfeld-Tanenbaum Research Institute The Lunenfeld-Tanenbaum Research Institute is a medical research institute in Toronto, Ontario and part of the Sinai Health System. It was originally established in 1985 as the Samuel Lunenfeld Research Institute, the research arm of Mount Si ...
{{DEFAULTSORT:McGee, Allison 1953 births Living people Canadian women physicians University of Toronto alumni Academic staff of the University of Toronto 20th-century Canadian physicians Women epidemiologists 20th-century women physicians 21st-century Canadian physicians 21st-century women physicians 20th-century Canadian women scientists Ontario COVID-19 Science Advisory Table