Thiomescaline (TM) is a pair of lesser-known psychedelic drugs with the molecular formula C₁₁H₁₇NO₂S. 3-TM and 4-TM are analogs of

mescaline Mescaline or mescalin (3,4,5-trimethoxyphenethylamine) is a naturally occurring psychedelic protoalkaloid of the substituted phenethylamine class, known for its hallucinogenic effects comparable to those of LSD and psilocybin. Biological sou ...

in which an oxygen atom has been replaced with a sulfur atom. They were first synthesized by

Alexander Shulgin Alexander Theodore "Sasha" Shulgin (June 17, 1925 – June 2, 2014) was an American medicinal chemist, biochemist, organic chemist, pharmacologist, psychopharmacologist, and author. He is credited with introducing 3,4-methylenedioxymethamph ...

and described in his book '' PiHKAL''.4-TM entry in ''PiHKAL''
/ref> Very little data exists on the pharmacological properties, metabolism, and toxicity of thiomescaline.

3-TM

''Dosage'': 60–100 mg ''Duration'': 8–12 hours ''Effects'': strong open and closed-eye visuals,

synesthesia Synesthesia (American English) or synaesthesia (British English) is a perceptual phenomenon in which stimulation of one sensory or cognitive pathway leads to involuntary experiences in a second sensory or cognitive pathway. People who re ...

upon listening to music, +++ on the

Shulgin Rating Scale The Shulgin Rating Scale (or "quantitative potency scale") is a simple scale for reporting the subjective effect of psychoactive substances at a given dosage, and at a given time. The system was developed for research purposes by the American bioche ...

4-TM

''Dosage'': 20–40 mg ''Duration'': 10–15 hours ''Effects'': LSD-like imagery and effects

References

{{reflist Psychedelic phenethylamines Thioethers

3-TM

4-TM

See also

References