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Strong Inference
In philosophy of science, strong inference is a model of scientific inquiry that emphasizes the need for alternative hypotheses, rather than a single hypothesis to avoid confirmation bias. The term "strong inference" was coined by John R. Platt, a biophysicist at the University of Chicago. Platt notes that some fields, such as molecular biology and high-energy physics, seem to adhere strongly to strong inference, with very beneficial results for the rate of progress in those fields. The single hypothesis problem The problem with single hypotheses, confirmation bias, was aptly described by Thomas Chrowder Chamberlin Thomas Chrowder Chamberlin (; September 25, 1843 – November 15, 1928) was an American geologist and educator. In 1893 he founded the '' Journal of Geology'', of which he was editor for many years. Biography Chamberlin was born September 25, 18 ... in 1897: Despite the admonitions of Platt, reviewers of grant-applications often require "A Hypothesis" as par ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Scientific Method
The scientific method is an empirical method for acquiring knowledge that has characterized the development of science since at least the 17th century (with notable practitioners in previous centuries; see the article history of scientific method for additional detail.) It involves careful observation, applying rigorous skepticism about what is observed, given that cognitive assumptions can distort how one interprets the observation. It involves formulating hypotheses, via induction, based on such observations; the testability of hypotheses, experimental and the measurement-based statistical testing of deductions drawn from the hypotheses; and refinement (or elimination) of the hypotheses based on the experimental findings. These are ''principles'' of the scientific method, as distinguished from a definitive series of steps applicable to all scientific enterprises. Although procedures vary from one field of inquiry to another, the underlying process is frequently the sa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Scientific Method
The scientific method is an empirical method for acquiring knowledge that has characterized the development of science since at least the 17th century (with notable practitioners in previous centuries; see the article history of scientific method for additional detail.) It involves careful observation, applying rigorous skepticism about what is observed, given that cognitive assumptions can distort how one interprets the observation. It involves formulating hypotheses, via induction, based on such observations; the testability of hypotheses, experimental and the measurement-based statistical testing of deductions drawn from the hypotheses; and refinement (or elimination) of the hypotheses based on the experimental findings. These are ''principles'' of the scientific method, as distinguished from a definitive series of steps applicable to all scientific enterprises. Although procedures vary from one field of inquiry to another, the underlying process is frequently the sa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Philosophy Of Science
Philosophy of science is a branch of philosophy concerned with the foundations, methods, and implications of science. The central questions of this study concern what qualifies as science, the reliability of scientific theories, and the ultimate purpose of science. This discipline overlaps with metaphysics, ontology, and epistemology, for example, when it explores the relationship between science and truth. Philosophy of science focuses on metaphysical, epistemic and semantic aspects of science. Ethical issues such as bioethics and scientific misconduct are often considered ethics or science studies rather than the philosophy of science. There is no consensus among philosophers about many of the central problems concerned with the philosophy of science, including whether science can reveal the truth about unobservable things and whether scientific reasoning can be justified at all. In addition to these general questions about science as a whole, philosophers of science consi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Model Of Scientific Inquiry
Models of scientific inquiry have two functions: first, to provide a descriptive account of ''how'' scientific inquiry is carried out in practice, and second, to provide an explanatory account of ''why'' scientific inquiry succeeds as well as it appears to do in arriving at genuine knowledge. The philosopher Wesley C. Salmon described scientific inquiry: The search for scientific knowledge ends far back into antiquity. At some point in the past, at least by the time of Aristotle, philosophers recognized that a fundamental distinction should be drawn between two kinds of scientific knowledge—roughly, knowledge ''that'' and knowledge ''why''. It is one thing to know ''that'' each planet periodically reverses the direction of its motion with respect to the background of fixed stars; it is quite a different matter to know ''why''. Knowledge of the former type is descriptive; knowledge of the latter type is explanatory. It is explanatory knowledge that provides scientific underst ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alternative Hypothesis
In statistical hypothesis testing, the alternative hypothesis is one of the proposed proposition in the hypothesis test. In general the goal of hypothesis test is to demonstrate that in the given condition, there is sufficient evidence supporting the credibility of alternative hypothesis instead of the exclusive proposition in the test (null hypothesis). It is usually consistent with the research hypothesis because it is constructed from literature review, previous studies, etc. However, the research hypothesis is sometimes consistent with the null hypothesis. In statistics, alternative hypothesis is often denoted as Ha or H1. Hypotheses are formulated to compare in a statistical hypothesis test. In the domain of inferential statistics two rival hypotheses can be compared by explanatory power and predictive power. Basic definition The ''alternative hypothesis'' and ''null hypothesis'' are types of conjectures used in statistical tests, which are formal methods of reaching ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Confirmation Bias
Confirmation bias is the tendency to search for, interpret, favor, and recall information in a way that confirms or supports one's prior beliefs or values. People display this bias when they select information that supports their views, ignoring contrary information, or when they interpret ambiguous evidence as supporting their existing attitudes. The effect is strongest for desired outcomes, for emotionally charged issues, and for deeply entrenched beliefs. Confirmation bias cannot be eliminated, but it can be managed, for example, by education and training in critical thinking skills. Biased search for information, biased interpretation of this information, and biased memory recall, have been invoked to explain four specific effects: # ''attitude polarization'' (when a disagreement becomes more extreme even though the different parties are exposed to the same evidence) # ''belief perseverance'' (when beliefs persist after the evidence for them is shown to be false) # the ''irr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
John R
John R. (born John Richbourg, August 20, 1910 - February 15, 1986) was an American radio disc jockey who attained fame in the 1950s and 1960s for playing rhythm and blues music on Nashville radio station WLAC. He was also a notable record producer and artist manager. Richbourg was arguably the most popular and charismatic of the four announcers at WLAC who showcased popular African-American music in nightly programs from the late 1940s to the early 1970s. (The other three were Gene Nobles, Herman Grizzard, and Bill "Hoss" Allen.) Later rock music disc jockeys, such as Alan Freed and Wolfman Jack, mimicked Richbourg's practice of using speech that simulated African-American street language of the mid-twentieth century. Richbourg's highly stylized approach to on-air presentation of both music and advertising earned him popularity, but it also created identity confusion. Because Richbourg and fellow disc jockey Allen used African-American speech patterns, many listeners thought that ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biophysics
Biophysics is an interdisciplinary science that applies approaches and methods traditionally used in physics to study biological phenomena. Biophysics covers all scales of biological organization, from molecular to organismic and populations. Biophysical research shares significant overlap with biochemistry, molecular biology, physical chemistry, physiology, nanotechnology, bioengineering, computational biology, biomechanics, developmental biology and systems biology. The term ''biophysics'' was originally introduced by Karl Pearson in 1892.Roland Glaser. Biophysics: An Introduction'. Springer; 23 April 2012. . The term ''biophysics'' is also regularly used in academia to indicate the study of the physical quantities (e.g. electric current, temperature, stress, entropy) in biological systems. Other biological sciences also perform research on the biophysical properties of living organisms including molecular biology, cell biology, chemical biology, and biochemistry. Overview ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Chicago
The University of Chicago (UChicago, Chicago, U of C, or UChi) is a private research university in Chicago, Illinois. Its main campus is located in Chicago's Hyde Park neighborhood. The University of Chicago is consistently ranked among the best universities in the world and it is among the most selective in the United States. The university is composed of an undergraduate college and five graduate research divisions, which contain all of the university's graduate programs and interdisciplinary committees. Chicago has eight professional schools: the Law School, the Booth School of Business, the Pritzker School of Medicine, the Crown Family School of Social Work, Policy, and Practice, the Harris School of Public Policy, the Divinity School, the Graham School of Continuing Liberal and Professional Studies, and the Pritzker School of Molecular Engineering. The university has additional campuses and centers in London, Paris, Beijing, Delhi, and Hong Kong, as well as in downtown ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Molecular Biology
Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The study of chemical and physical structure of biological macromolecules is known as molecular biology. Molecular biology was first described as an approach focused on the underpinnings of biological phenomena - uncovering the structures of biological molecules as well as their interactions, and how these interactions explain observations of classical biology. In 1945 the term molecular biology was used by physicist William Astbury. In 1953 Francis Crick, James Watson, Rosalind Franklin, and colleagues, working at Medical Research Council unit, Cavendish laboratory, Cambridge (now the MRC Laboratory of Molecular Biology), made a double helix model of DNA which changed the entire research scenario. They proposed the DNA structure based on previous research done by Ro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
High-energy Physics
Particle physics or high energy physics is the study of fundamental particles and forces that constitute matter and radiation. The fundamental particles in the universe are classified in the Standard Model as fermions (matter particles) and bosons (force-carrying particles). There are three generations of fermions, but ordinary matter is made only from the first fermion generation. The first generation consists of up and down quarks which form protons and neutrons, and electrons and electron neutrinos. The three fundamental interactions known to be mediated by bosons are electromagnetism, the weak interaction, and the strong interaction. Quarks cannot exist on their own but form hadrons. Hadrons that contain an odd number of quarks are called baryons and those that contain an even number are called mesons. Two baryons, the proton and the neutron, make up most of the mass of ordinary matter. Mesons are unstable and the longest-lived last for only a few hundredths of a mic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thomas Chrowder Chamberlin
Thomas Chrowder Chamberlin (; September 25, 1843 – November 15, 1928) was an American geologist and educator. In 1893 he founded the ''Journal of Geology'', of which he was editor for many years. Biography Chamberlin was born September 25, 1843, in Mattoon, Illinois. When he was three years old his family moved north to near Beloit, Wisconsin. His father was a Methodist circuit minister and farmer. He attended a preparatory academy before entering Beloit College, where he received a classical education in Greek and Latin, while becoming interested in natural science. While a student at Beloit he directed a church choir and participated in athletics and debate. After graduation from Beloit College in 1866, Chamberlin worked for two years as a teacher and later principal in a high school near Beloit. He was married to Alma Wilson in 1867. In 1868–1869, Chamberlin spent a year taking graduate courses, including geology, at the University of Michigan to strengthen his scientific ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
