Rosetting
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Rosetting
Erythrocyte rosetting or E-rosetting is a phenomenon seen through a microscope where red blood cells ''(erythrocytes)'' are arranged around a central cell to form a cluster that looks like a flower. The red blood cells surrounding the cell form the ''petal,'' while the central cell forms the ''stigma'' of the flower shape. This formation occurs due to an Immunology, immunological reaction between an epitope on the central cell's surface and a receptor or antibody on a red cell. The presence of E-rosetting can be used as a test for T cells although more modern tests such as immunohistochemistry are available. Rosetting is caused by parasites in the genus ''Plasmodium'' and is a cause of some malaria-associated symptoms. Rosetting techniques Three types of rosette techniques have been developed and used experimentally. Rosette test for Rh factor The ''Rosette test'' is performed on postpartum maternal blood to estimate the volume of fetal-maternal hemorrhage in case of an Rh nega ...
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Microscope
A microscope () is a laboratory instrument used to examine objects that are too small to be seen by the naked eye. Microscopy is the science of investigating small objects and structures using a microscope. Microscopic means being invisible to the eye unless aided by a microscope. There are many types of microscopes, and they may be grouped in different ways. One way is to describe the method an instrument uses to interact with a sample and produce images, either by sending a beam of light or electrons through a sample in its optical path, by detecting photon emissions from a sample, or by scanning across and a short distance from the surface of a sample using a probe. The most common microscope (and the first to be invented) is the optical microscope, which uses lenses to refract visible light that passed through a thinly sectioned sample to produce an observable image. Other major types of microscopes are the fluorescence microscope, electron microscope (both the transmi ...
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