HOME



picture info

Protein Families
A protein family is a group of evolution Evolution is change in the heritable Heredity, also called inheritance or biological inheritance, is the passing on of Phenotypic trait, traits from parents to their offspring; either through asexual reproduction or sexual reproduction, ...arily related protein Proteins are large biomolecule , showing alpha helices, represented by ribbons. This poten was the first to have its suckture solved by X-ray crystallography by Max Perutz and Sir John Cowdery Kendrew in 1958, for which they received a No ...s. In many cases, a protein family has a corresponding gene family A gene family is a set of several similar genes, formed by duplication of a single original gene In biology, a gene (from ''genos'' "...Wilhelm Johannsen coined the word gene to describe the Mendelian_inheritance#History, Mendelian units of ..., in which each gene encodes a corresponding protein with a 1:1 relationship. The term "protein family" sho ...
[...More Info...]      
[...Related Items...]



picture info

Structural Coverage Of The Human Cyclophilin Family
A structure is an arrangement and organization of interrelated elements in a material object or system, or the object or system so organized. Material structures include man-made objects such as buildings and machines and natural objects such as organism, biological organisms, minerals and chemical substance, chemicals. Abstract structures include data structures in computer science and musical form. Types of structure include a hierarchy (a cascade of one-to-many relationships), a Complex network, network featuring many-to-many Link (geometry), links, or a lattice (order), lattice featuring connections between components that are neighbors in space. Load-bearing Buildings, aircraft, skeletons, Ant colony, anthills, beaver dams, bridges and salt domes are all examples of Structural load, load-bearing structures. The results of construction are divided into buildings and nonbuilding structure, non-building structures, and make up the infrastructure of a human society. Built str ...
[...More Info...]      
[...Related Items...]



picture info

Superfamily (molecular Biology)
A protein superfamily is the largest grouping (clade) of proteins for which common ancestry can be inferred (see homology (biology), homology). Usually this common ancestry is inferred from structural alignment and mechanistic similarity, even if no sequence similarity is evident. Sequence homology can then be deduced even if not apparent (due to low sequence similarity). Superfamilies typically contain several protein families which show sequence similarity within each family. The term ''protein clan'' is commonly used for protease and glycosyl hydrolases superfamilies based on the MEROPS and CAZy classification systems. Identification Superfamilies of proteins are identified using a number of methods. Closely related members can be identified by different methods to those needed to group the most evolutionarily divergent members. Sequence similarity Historically, the similarity of different amino acid sequences has been the most common method of inferring Sequence homology, ...
[...More Info...]      
[...Related Items...]



picture info

Ortholog
Sequence homology is the biological homology between DNA Deoxyribonucleic acid (; DNA) is a molecule File:Pentacene on Ni(111) STM.jpg, A scanning tunneling microscopy image of pentacene molecules, which consist of linear chains of five carbon rings. A molecule is an electrically neutral gro ..., RNA Ribonucleic acid (RNA) is a polymer A polymer (; Greek ''wikt:poly-, poly-'', "many" + ''wikt:-mer, -mer'', "part") is a Chemical substance, substance or material consisting of very large molecules, or macromolecules, composed of many Re ..., or protein sequences Protein primary structure is the linear sequence of amino acid Amino acids are organic compounds that contain amino (–NH2) and Carboxylic acid, carboxyl (–COOH) functional groups, along with a Substituent, side chain (R group) specific to ..., defined in terms of shared ancestry in the evolutionary history of life The history of life on Earth Earth is the third planet from the ...
[...More Info...]      
[...Related Items...]



picture info

Mutations
In biology Biology is the natural science that studies life and living organisms, including their anatomy, physical structure, Biochemistry, chemical processes, Molecular biology, molecular interactions, Physiology, physiological mechanisms, Development ..., a mutation is an alteration in the nucleotide sequence A nucleic acid sequence is a succession of bases signified by a series of a set of five different letters that indicate the order of nucleotides Nucleotides are organic molecules consisting of a nucleoside and a phosphate. They serve as monom ... of the genome In the fields of molecular biology Molecular biology is the branch of biology Biology is the natural science that studies life and living organisms, including their anatomy, physical structure, Biochemistry, chemical processes, M ... of an organism In biology Biology is the natural science that studies life and living organisms, including their anatomy, physical ...
[...More Info...]      
[...Related Items...]



picture info

Multiple Sequence Alignment
Multiple sequence alignment (MSA) may refer to the process or the result of sequence alignment In bioinformatics Bioinformatics () is an field that develops methods and s for understanding data, in particular when the data sets are large and complex. As an interdisciplinary field of science, bioinformatics combines , , , and to ... of three or more biological sequences, generally protein Proteins are large biomolecule , showing alpha helices, represented by ribbons. This poten was the first to have its suckture solved by X-ray crystallography by Max Perutz and Sir John Cowdery Kendrew in 1958, for which they received a No ..., DNA Deoxyribonucleic acid (; DNA) is a molecule File:Pentacene on Ni(111) STM.jpg, A scanning tunneling microscopy image of pentacene molecules, which consist of linear chains of five carbon rings. A molecule is an electrically neutral gro ..., or RNA Ribonucleic acid (RNA) is a polymer A polymer (; Greek ''wi ...
[...More Info...]      
[...Related Items...]



picture info

Hydrophobicity
In chemistry Chemistry is the scientific Science () is a systematic enterprise that builds and organizes knowledge Knowledge is a familiarity or awareness, of someone or something, such as facts A fact is an occurrence in the real world. T ..., hydrophobicity is the physical property of a molecule A molecule is an electrically Electricity is the set of physical phenomena associated with the presence and motion Image:Leaving Yongsan Station.jpg, 300px, Motion involves a change in position In physics, motion is the phenomenon ... that is seemingly repelled from a mass of water Water (chemical formula H2O) is an Inorganic compound, inorganic, transparent, tasteless, odorless, and Color of water, nearly colorless chemical substance, which is the main constituent of Earth's hydrosphere and the fluids of all known li ... (known as a hydrophobe). (There is no repulsive force involved; it is an absence of attraction.) In contrast, hyd ...
[...More Info...]      
[...Related Items...]



Active Site
Active may refer to: Music * ''Active'' (album), a 1992 album by Casiopea * Active Records Active Records was a record label, record sublabel of RCA Records founded in 1980. The label focused mainly on heavy metal music. The label was dissolved in 1994. Bands * Anacrusis (band), Anacrusis * Atheist (band), Atheist * Budgie (band), Budgi ..., a record label Ships * ''Active'' (ship), several commercial ships by that name * HMS ''Active'', the name of various ships of the British Royal Navy * USCS ''Active'', a US Coast Survey ship in commission from 1852 to 1861 * USCGC ''Active'', the name of various ships of the US Coast Guard * USRC ''Active'', the name of various ships of the US Revenue Cutter Service * USS ''Active'', the name of various ships of the US Navy Computers and electronics * Active Enterprises ''Action 52'' is an unlicensed, multicart video game compilation developed by Active Enterprises for the Nintendo Entertainment System, and by FarSight Stu ...
[...More Info...]      
[...Related Items...]



picture info

Shuffling
Shuffling is a procedure used to randomization, randomize a deck of playing cards to provide an element of chance in card games. Shuffling is often followed by a cut (cards), cut, to help ensure that the shuffler has not manipulated the outcome. __TOC__ Techniques Overhand One of the easiest shuffles to accomplish after a little practice is the overhand shuffle. Johan Jonasson wrote, "The overhand shuffle... is the shuffling technique where you gradually transfer the deck from, say, your right hand to your left hand by sliding off small packets from the top of the deck with your thumb." In detail as normally performed, with the pack initially held in the left hand (say), most of the cards are grasped as a group from the bottom of the pack between the thumb and fingers of the right hand and lifted clear of the small group that remains in the left hand. Small packets are then released from the right hand a packet at a time so that they drop on the top of the pack accumulating in ...
[...More Info...]      
[...Related Items...]



picture info

Protein Domain
A protein domain is a region of the protein's Peptide, polypeptide chain that is self-stabilizing and that folds independently from the rest. Each domain forms a compact protein folding, folded three-dimensional structure. Many proteins consist of several domains. One domain may appear in a variety of different proteins. Molecular evolution uses domains as building blocks and these may be recombined in different arrangements to create proteins with different functions. In general, domains vary in length from between about 50 amino acids up to 250 amino acids in length. The shortest domains, such as zinc fingers, are stabilized by metal ions or Disulfide bond, disulfide bridges. Domains often form functional units, such as the calcium-binding EF-hand, EF hand domain of calmodulin. Because they are independently stable, domains can be "swapped" by genetic engineering between one protein and another to make chimera (protein), chimeric proteins. Background The concept of the domain w ...
[...More Info...]      
[...Related Items...]



picture info

Cytochrome C
The cytochrome complex, or cyt ''c'', is a small hemeprotein found loosely associated with the inner membrane of the mitochondrion A mitochondrion (; ) is a double-membrane Image:Schematic size.jpg, up150px, Schematic of size-based membrane exclusion A membrane is a selective barrier; it allows some things to pass through but stops others. Such things may be molecules, i .... It belongs to the cytochrome c family Cytochromes ''c'' (cyt ''c'', c-type cytochromes) , or -containing s, that have attached to the peptide backbone via one or two bonds. These bonds are in most cases part of a specific -X-X-Cys- (CXXCH) , where X denotes a miscellaneous . Two thi ... of proteins and plays a major role in cell apoptosis Apoptosis (from Ancient Greek Ancient Greek includes the forms of the Greek language Greek ( el, label=Modern Greek Modern Greek (, , or , ''Kiní Neoellinikí Glóssa''), generally referred to by speakers simply as Greek (, ) .... Cytochro ...
[...More Info...]      
[...Related Items...]



picture info

Hemoglobin
Hemoglobin or haemoglobin (spelling differences Despite the various English dialects Dialect The term dialect (from Latin , , from the Ancient Greek word , , "discourse", from , , "through" and , , "I speak") is used in two distinct ways to refer to two different types of Linguistics, ...) (from the Greek word αἷμα, ''haîma'' 'blood' + Latin ''globus'' 'ball, sphere' + ''-in'') (), abbreviated Hb or Hgb, is the iron Iron () is a with Fe (from la, ) and 26. It is a that belongs to the and of the . It is, on , right in front of (32.1% and 30.1%, respectively), forming much of Earth's and . It is the fourth most common . In its metallic state, iron ...-containing oxygen Oxygen is the chemical element Image:Simple Periodic Table Chart-blocks.svg, 400px, Periodic table, The periodic table of the chemical elements In chemistry, an element is a pure substance consisting only of atoms that all have the same ...-transport metalloprotein Met ...
[...More Info...]      
[...Related Items...]



picture info

Myoglobin
Myoglobin (symbol Mb or MB) is an iron Iron () is a chemical element In chemistry Chemistry is the study of the properties and behavior of . It is a that covers the that make up matter to the composed of s, s and s: their composition, structure, properties, behav ...- and oxygen Oxygen is the chemical element Image:Simple Periodic Table Chart-blocks.svg, 400px, Periodic table, The periodic table of the chemical elements In chemistry, an element is a pure substance consisting only of atoms that all have the same ...-binding protein Proteins are large biomolecule , showing alpha helices, represented by ribbons. This poten was the first to have its suckture solved by X-ray crystallography by Max Perutz and Sir John Cowdery Kendrew in 1958, for which they received a No ... found in the cardiac and skeletal The skeleton refers to the frames of support of animal bodies. There are several different skeletal types: the exoskeleton An ...
[...More Info...]      
[...Related Items...]