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Phenomics
Phenomics is the systematic study of traits that make up a phenotype, and was coined by UC Berkeley and LBNL scientist Steven A. Garan. As such, it is a transdisciplinary area of research that involves biology, data sciences, engineering and other fields. Phenomics is concerned with the measurement of the phenotype where a phenome is a set of traits (physical and biochemical traits) that can be produced by a given organism over the course of development and in response to genetic mutation and environmental influences. The relationship between phenotype and genotype enables researchers to understand and study pleiotropy. Phenomics concepts are used in functional genomics, pharmaceutical research, metabolic engineering, agricultural research, and increasingly in phylogenetics. Technical challenges involve improving, both qualitatively and quantitatively, the capacity to measure phenomes. Applications Plant sciences In plant sciences, phenomics research occurs in both field an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phenomics
Phenomics is the systematic study of traits that make up a phenotype, and was coined by UC Berkeley and LBNL scientist Steven A. Garan. As such, it is a transdisciplinary area of research that involves biology, data sciences, engineering and other fields. Phenomics is concerned with the measurement of the phenotype where a phenome is a set of traits (physical and biochemical traits) that can be produced by a given organism over the course of development and in response to genetic mutation and environmental influences. The relationship between phenotype and genotype enables researchers to understand and study pleiotropy. Phenomics concepts are used in functional genomics, pharmaceutical research, metabolic engineering, agricultural research, and increasingly in phylogenetics. Technical challenges involve improving, both qualitatively and quantitatively, the capacity to measure phenomes. Applications Plant sciences In plant sciences, phenomics research occurs in both field an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phenotype
In genetics, the phenotype () is the set of observable characteristics or traits of an organism. The term covers the organism's morphology or physical form and structure, its developmental processes, its biochemical and physiological properties, its behavior, and the products of behavior. An organism's phenotype results from two basic factors: the expression of an organism's genetic code, or its genotype, and the influence of environmental factors. Both factors may interact, further affecting phenotype. When two or more clearly different phenotypes exist in the same population of a species, the species is called polymorphic. A well-documented example of polymorphism is Labrador Retriever coloring; while the coat color depends on many genes, it is clearly seen in the environment as yellow, black, and brown. Richard Dawkins in 1978 and then again in his 1982 book ''The Extended Phenotype'' suggested that one can regard bird nests and other built structures such as cad ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
PhenomicDB
PhenomicDB is a free phenotype oriented database. It contains data for some of the main model organisms such as ''Homo sapiens, Mus musculus, Drosophila melanogaster'', and others. PhenomicDB merges and structures phenotypic data from various public sources: WormBase, FlyBase, NCBI Gene, MGI, and ZFIN The Zebrafish Information NetworkZFIN is an online biological database of information about the zebrafish (''Danio rerio''). The zebrafish is a widely used model organism for genetic, genomic, and developmental studies, and ZFIN provides an integra ... using clustering algorithms. The website is currently offline. References Further reading * * * * * External links * Phenomics Biological databases {{bioinformatics-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The University Of Arizona
The University of Arizona (Arizona, U of A, UArizona, or UA) is a public land-grant research university in Tucson, Arizona. Founded in 1885 by the 13th Arizona Territorial Legislature, it was the first university in the Arizona Territory. The university is part of the Association of American Universities and the Universities Research Association. In the former, it is the only member from the state of Arizona. The university is classified among "R1: Doctoral Universities – Very High Research Activity". The University of Arizona is one of three universities governed by the Arizona Board of Regents. , the university enrolled 49,471 students in 19 separate colleges/schools, including the University of Arizona College of Medicine in Tucson and Phoenix and the James E. Rogers College of Law, and is affiliated with two academic medical centers ( Banner – University Medical Center Tucson and Banner – University Medical Center Phoenix). In 2021, University of Arizona acquire ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Phenotype Ontology
The Human Phenotype Ontology (HPO) is a formal ontology of human phenotypes. Developed in collaboration with members of the Open Biomedical Ontologies Foundry, HPO currently contains over 13,000 terms and over 156,000 annotations to hereditary diseases. Data from Online Mendelian Inheritance in Man and medical literature were used to generate the terms currently in the HPO. The ontology contains over 50,000 annotations between phenotypes and hereditary disease. Motivation The Human Phenotype Ontology (HPO) was created to serve as a standardized vocabulary of phenotypic abnormalities that have been seen in human disease. Applications for the data in the ontology include clinical diagnostics, mapping between phenotypes of model organisms, and as a standard vocabulary for clinical databases. Clinical annotations within the HPO are sought from the medical and genetics community to improve the ontology. See also *Disease Ontology *Gene Ontology The Gene Ontology (GO) is a major bioi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phenotype Microarray
The phenotype microarray approach is a technology for high-throughput phenotyping of cells. A phenotype microarray system enables one to monitor simultaneously the phenotypic reaction of cells to environmental challenges or exogenous compounds in a high-throughput manner. The phenotypic reactions are recorded as either end-point measurements or respiration kinetics similar to growth curves. Usages High-throughput phenotypic testing is increasingly important for exploring the biology of bacteria, fungi, yeasts, and animal cell lines such as human cancer cells. Just as DNA microarrays and proteomic technologies have made it possible to assay the expression level of thousands of genes or proteins all a once, phenotype microarrays (PMs) make it possible to quantitatively measure thousands of cellular phenotypes simultaneously. The approach also offers potential for testing gene function and improving genome annotation. In contrast to many of the hitherto available molecular high- ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Nebraska-Lincoln
A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. Universities typically offer both undergraduate and postgraduate programs. In the United States, the designation is reserved for colleges that have a graduate school. The word ''university'' is derived from the Latin ''universitas magistrorum et scholarium'', which roughly means "community of teachers and scholars". The first universities were created in Europe by Catholic Church monks. The University of Bologna (''Università di Bologna''), founded in 1088, is the first university in the sense of: *Being a high degree-awarding institute. *Having independence from the ecclesiastic schools, although conducted by both clergy and non-clergy. *Using the word ''universitas'' (which was coined at its foundation). *Issuing secular and non-secular degrees: grammar, rhetoric, logic, theology, canon law, notarial law.Hunt Janin: "The university ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Donald Danforth Plant Science Center
The Donald Danforth Plant Science Center is an independent, not-for-profit research institute dedicated to plant science located in the Creve Coeur community of Saint Louis County, Missouri, United States. It was founded in 1998 by William Henry Danforth, chancellor emeritus of Washington University in St. Louis and named after his father, and established through a $60 million gift from the Danforth Foundation, a $50 million gift from the Monsanto Fund, the donation of 40 acres of land from Monsanto, and $25 million in tax credits from the State of Missouri. The Center has a $30 million annual operating budget, a $300 million endowment, and 242 employees, including 30 principal investigators. It is home to the Enterprise Rent-A-Car Institute for Renewable Fuels and the International Institute for Crop Improvement. The Danforth Center Core Facilities include bioinformatics, integrated microscopy, phenotyping, plant growth, proteomics and mass spectrometry, and tissue culture ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Iowa State University
Iowa State University of Science and Technology (Iowa State University, Iowa State, or ISU) is a public land-grant research university in Ames, Iowa. Founded in 1858 as the Iowa Agricultural College and Model Farm, Iowa State became one of the nation's first designated land-grant institution when the Iowa Legislature accepted the provisions of the 1862 Morrill Act on September 11, 1862, making Iowa the first state in the nation to do so. On July 4, 1959, the college was officially renamed Iowa State University of Science and Technology. Iowa State is classified among "R1: Doctoral Universities – Very high research activity". The university is home to the Ames Laboratory, one of ten national U.S. Department of Energy Office of Science research laboratories, the Biorenewables Research Laboratory, the Plant Sciences Institute, and various other research institutes. Iowa State is the second-largest university in the State of Iowa by undergraduate enrollment. The university's ac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phylogenetics
In biology, phylogenetics (; from Greek language, Greek wikt:φυλή, φυλή/wikt:φῦλον, φῦλον [] "tribe, clan, race", and wikt:γενετικός, γενετικός [] "origin, source, birth") is the study of the evolutionary history and relationships among or within groups of organisms. These relationships are determined by Computational phylogenetics, phylogenetic inference methods that focus on observed heritable traits, such as DNA sequences, Protein, protein Amino acid, amino acid sequences, or Morphology (biology), morphology. The result of such an analysis is a phylogenetic tree—a diagram containing a hypothesis of relationships that reflects the evolutionary history of a group of organisms. The tips of a phylogenetic tree can be living taxa or fossils, and represent the "end" or the present time in an evolutionary lineage. A phylogenetic diagram can be rooted or unrooted. A rooted tree diagram indicates the hypothetical common ancestor of the tree. An un ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biology
Biology is the scientific study of life. It is a natural science with a broad scope but has several unifying themes that tie it together as a single, coherent field. For instance, all organisms are made up of cells that process hereditary information encoded in genes, which can be transmitted to future generations. Another major theme is evolution, which explains the unity and diversity of life. Energy processing is also important to life as it allows organisms to move, grow, and reproduce. Finally, all organisms are able to regulate their own internal environments. Biologists are able to study life at multiple levels of organization, from the molecular biology of a cell to the anatomy and physiology of plants and animals, and evolution of populations.Based on definition from: Hence, there are multiple subdisciplines within biology, each defined by the nature of their research questions and the tools that they use. Like other scientists, biologists use the sc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Agricultural Research
Agricultural science (or agriscience for short) is a broad multidisciplinary field of biology that encompasses the parts of exact, natural, economic and social sciences that are used in the practice and understanding of agriculture. Professionals of the agricultural science are called agricultural scientists or agriculturists. History In the 18th century, Johann Friedrich Mayer conducted experiments on the use of gypsum (hydrated calcium sulphate) as a fertilizer.John Armstrong, Jesse Buel. ''A Treatise on Agriculture, The Present Condition of the Art Abroad and at Home, and the Theory and Practice of Husbandry. To which is Added, a Dissertation on the Kitchen and Garden.'' 1840. p. 45. In 1843, John Bennet Lawes and Joseph Henry Gilbert began a set of long-term field experiments at Rothamsted Research in England, some of which are still running as of 2018. In the United States, a scientific revolution in agriculture began with the Hatch Act of 1887, which used the term " ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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