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Molecular Cell Biology
Cell biology (also cellular biology or cytology) is a branch of biology that studies the structure, function, and behavior of cells. All living organisms are made of cells. A cell is the basic unit of life that is responsible for the living and functioning of organisms. Cell biology is the study of structural and functional units of cells. Cell biology encompasses both prokaryotic and eukaryotic cells and has many subtopics which may include the study of cell metabolism, cell communication, cell cycle, biochemistry, and cell composition. The study of cells is performed using several microscopy techniques, cell culture, and cell fractionation. These have allowed for and are currently being used for discoveries and research pertaining to how cells function, ultimately giving insight into understanding larger organisms. Knowing the components of cells and how cells work is fundamental to all biological sciences while also being essential for research in biomedical fields such as ca ...
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Biology
Biology is the scientific study of life. It is a natural science with a broad scope but has several unifying themes that tie it together as a single, coherent field. For instance, all organisms are made up of cells that process hereditary information encoded in genes, which can be transmitted to future generations. Another major theme is evolution, which explains the unity and diversity of life. Energy processing is also important to life as it allows organisms to move, grow, and reproduce. Finally, all organisms are able to regulate their own internal environments. Biologists are able to study life at multiple levels of organization, from the molecular biology of a cell to the anatomy and physiology of plants and animals, and evolution of populations.Based on definition from: Hence, there are multiple subdisciplines within biology, each defined by the nature of their research questions and the tools that they use. Like other scientists, biologists use the sc ...
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Molecular Genetics
Molecular genetics is a sub-field of biology that addresses how differences in the structures or expression of DNA molecules manifests as variation among organisms. Molecular genetics often applies an "investigative approach" to determine the structure and/or function of genes in an organism's genome using genetic screens.  The field of study is based on the merging of several sub-fields in biology: classical Mendelian inheritance, Cell biology, cellular biology, molecular biology, biochemistry, and biotechnology. Researchers search for mutations in a gene or induce mutations in a gene to link a gene sequence to a specific phenotype. Molecular genetics is a powerful methodology for linking mutations to genetic conditions that may aid the search for treatments/cures for various genetics diseases. History For molecular genetics to develop as a discipline, several scientific discoveries were necessary.  The discovery of DNA as a means to transfer the genetic code of life f ...
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Theodor Schwann
Theodor Schwann (; 7 December 181011 January 1882) was a German physician and physiologist. His most significant contribution to biology is considered to be the extension of cell theory to animals. Other contributions include the discovery of Schwann cells in the peripheral nervous system, the discovery and study of pepsin, the discovery of the organic nature of yeast, and the invention of the term "metabolism". Early life and education Theodor Schwann was born in Neuss on 7 December 1810 to Leonard Schwann and Elisabeth Rottels. Leonard Schwann was a goldsmith and later a printer. Theodor Schwann studied at the Dreikönigsgymnasium (also known as the Tricoronatum or Three Kings School), a Jesuit school in Cologne. Schwann was a devout Roman Catholic. In Cologne his religious instructor , a priest and novelist, emphasized the individuality of the human soul and the importance of free will. In 1829, Schwann enrolled at the University of Bonn in the premedical curriculum. ...
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Matthias Jakob Schleiden
Matthias Jakob Schleiden (; 5 April 1804 – 23 June 1881) was a German botanist and co-founder of cell theory, along with Theodor Schwann and Rudolf Virchow. Career Matthias Jakob Schleiden was born in Hamburg. on 5 April 1804. His father was the municipal physician of Hamburg. Schleiden pursued legal studies graduating in 1827. He then established a legal practice but after a period of emotional depression and attempted suicide, he changed professions. He studied natural science at the University of Göttingen in Göttingen, Germany, but transferred to the University of Berlin in 1835 to study plants. Johann Horkel, Schleiden's uncle, encouraged him to study plant embryology. He soon developed his love for botany and cats into a full-time pursuit. Schleiden preferred to study plant structure under the microscope. As a professor of botany at the University of Jena, he wrote ''Contributions to our Knowledge of Phytogenesis'' (1838), in which he stated that all plants are ...
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Cell Theory
In biology, cell theory is a scientific theory first formulated in the mid-nineteenth century, that living organisms are made up of Cell (biology), cells, that they are the basic structural/organizational unit of all organisms, and that all cells come from pre-existing cells. Cells are the basic unit of structure in all organisms and also the basic unit of reproduction. The three tenets of the cell theory are: # All living organisms are composed of one or more cells. # The cell is the basic unit of structure and organization in organisms. # Cells arise from pre-existing cells. The theory was once universally accepted, but now some biologists consider non-cellular life, non-cellular entities such as viruses living organisms, and thus disagree with the first tenet. As of 2021: "expert opinion remains divided roughly a third each between yes, no and don’t know". As there is no universally accepted definition of Life#Definition, life, discussion will continue. History With contin ...
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Algae
Algae (; singular alga ) is an informal term for a large and diverse group of photosynthetic eukaryotic organisms. It is a polyphyletic grouping that includes species from multiple distinct clades. Included organisms range from unicellular microalgae, such as ''Chlorella,'' ''Prototheca'' and the diatoms, to multicellular forms, such as the giant kelp, a large brown alga which may grow up to in length. Most are aquatic and autotrophic (they generate food internally) and lack many of the distinct cell and tissue types, such as stomata, xylem and phloem that are found in land plants. The largest and most complex marine algae are called seaweeds, while the most complex freshwater forms are the ''Charophyta'', a division of green algae which includes, for example, ''Spirogyra'' and stoneworts. No definition of algae is generally accepted. One definition is that algae "have chlorophyll ''a'' as their primary photosynthetic pigment and lack a sterile covering of cells around thei ...
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Anton Van Leeuwenhoek
Antonie Philips van Leeuwenhoek ( ; ; 24 October 1632 – 26 August 1723) was a Dutch microbiologist and microscopist in the Golden Age of Dutch science and technology. A largely self-taught man in science, he is commonly known as " the Father of Microbiology", and one of the first microscopists and microbiologists. Van Leeuwenhoek is best known for his pioneering work in microscopy and for his contributions toward the establishment of microbiology as a scientific discipline. Raised in Delft, Dutch Republic, van Leeuwenhoek worked as a draper in his youth and founded his own shop in 1654. He became well recognized in municipal politics and developed an interest in lensmaking. In the 1670s, he started to explore microbial life with his microscope. This was one of the notable achievements of the Golden Age of Dutch exploration and discovery (). Using single-lensed microscopes of his own design and make, van Leeuwenhoek was the first to observe and to experiment with microbe ...
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Cork (material)
Cork is an Permeability (earth sciences), impermeable buoyancy, buoyant material, the Cork cambium, phellem layer of bark (botany), bark tissue that is harvested for commercial use primarily from ''Quercus suber'' (the cork oak), which is native to southwest Europe and northwest Africa. Cork is composed of suberin, a hydrophobic substance. Because of its impermeable, buoyant, elastic, and fire retardant properties, it is used in a variety of products, the most common of which is wine stoppers. The Dehesa (pastoral management), montado landscape of Portugal produces approximately half of the cork harvested annually worldwide, with Corticeira Amorim being the leading company in the industry. Cork was examined microscopically by Robert Hooke, which led to his discovery and naming of the cell (biology), cell. Cork composition varies depending on Geography, geographic origin, climate and soil conditions, Genetics, genetic origin, tree dimensions, age (virgin or reproduction), and gro ...
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Micrographia
''Micrographia: or Some Physiological Descriptions of Minute Bodies Made by Magnifying Glasses. With Observations and Inquiries Thereupon.'' is a historically significant book by Robert Hooke about his observations through various lenses. It was the first book to include illustrations of insects and plants as seen through microscopes. Published in January 1665, the first major publication of the Royal Society, it became the first scientific best-seller, inspiring a wide public interest in the new science of microscopy. The book originated the biological term ''cell''. Observations Hooke most famously describes a fly's eye and a plant cell (where he coined that term because plant cells, which are walled, reminded him of the cells in a honeycomb"... I could exceedingly plainly perceive it to be all perforated and porous, much like a Honey-comb, but that the pores of it were not regular .these pores, or cells, .were indeed the first microscopical pores I ever saw, and perhaps, ...
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Robert Hooke
Robert Hooke FRS (; 18 July 16353 March 1703) was an English polymath active as a scientist, natural philosopher and architect, who is credited to be one of two scientists to discover microorganisms in 1665 using a compound microscope that he built himself, the other scientist being Antoni van Leeuwenhoek in 1676. An impoverished scientific inquirer in young adulthood, he found wealth and esteem by performing over half of the architectural surveys after London's great fire of 1666. Hooke was also a member of the Royal Society and since 1662 was its curator of experiments. Hooke was also Professor of Geometry at Gresham College. As an assistant to physical scientist Robert Boyle, Hooke built the vacuum pumps used in Boyle's experiments on gas law, and himself conducted experiments. In 1673, Hooke built the earliest Gregorian telescope, and then he observed the rotations of the planets Mars and Jupiter. Hooke's 1665 book ''Micrographia'', in which he coined the term "cell", ...
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Optical Microscope
The optical microscope, also referred to as a light microscope, is a type of microscope that commonly uses visible light and a system of lenses to generate magnified images of small objects. Optical microscopes are the oldest design of microscope and were possibly invented in their present compound form in the 17th century. Basic optical microscopes can be very simple, although many complex designs aim to improve resolution and sample contrast. The object is placed on a stage and may be directly viewed through one or two eyepieces on the microscope. In high-power microscopes, both eyepieces typically show the same image, but with a stereo microscope, slightly different images are used to create a 3-D effect. A camera is typically used to capture the image (micrograph). The sample can be lit in a variety of ways. Transparent objects can be lit from below and solid objects can be lit with light coming through ( bright field) or around (dark field) the objective lens. Polarised ...
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Cytochemistry
Cytochemistry is the branch of cell biology dealing with the detection of cell constituents by means of biochemical analysis and visualization techniques. This is the study of the localization of cellular components through the use of staining methods. The term is also used to describe a process of identification of the biochemical content of cells. ''Cytochemistry'' is a science of localizing chemical components of cells and cell organelles on thin histological sections by using several techniques like enzyme localization, micro-incineration, micro-spectrophotometry, radioautography, cryo-electron microscopy, X-ray microanalysis by energy-dispersive X-ray spectroscopy Energy-dispersive X-ray spectroscopy (EDS, EDX, EDXS or XEDS), sometimes called energy dispersive X-ray analysis (EDXA or EDAX) or energy dispersive X-ray microanalysis (EDXMA), is an analytical technique used for the elemental analysis or chemi ..., immunohistochemistry and cytochemistry, etc. Freeze Fracture ...
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