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Legume Lectin
{{Infobox protein family , Symbol = Lectin_legB , Name = Legume lectin domain (or L-type lectin domain) , image = PDB 1lem EBI.jpg , width = , caption = Structure of the monosaccharide binding site of lentil lectin.{{cite journal , vauthors=Loris R, Casset F, Bouckaert J, etal , title=The monosaccharide binding site of lentil lectin: an X-ray and molecular modelling study , journal=Glycoconj. J. , volume=11 , issue=6 , pages=507–17 , date=December 1994 , pmid=7696853 , doi= 10.1007/bf00731301, s2cid=20037257 , Pfam = PF00139 , Pfam_clan = CL0004 , InterPro = IPR001220 , SMART = , PROSITE = PDOC00278 , MEROPS = , SCOP = 1lem , TCDB = , OPM family = , OPM protein = , PDB = {{PDB2, 1apn, {{PDB2, 1avb, {{PDB2, 1ax0, {{PDB2, 1ax1, {{PDB2, 1ax2, {{PDB2, 1axy, {{PDB2, 1axz, {{PDB2, 1azd, {{PDB2, 1bjq, {{PDB2, 1bqp, {{PDB2, 1bxh, {{PDB2, 1bzw, {{PDB2, 1ces, {{PDB2, 1ciw, {{PDB2, 1cjp, {{PDB2, 1cn1, {{PDB2, 1con, {{PDB2, 1cq9, {{PDB2, 1cr7, {{PDB2, 1cvn, {{PDB2, 1dbn, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lectin
Lectins are carbohydrate-binding proteins that are highly specific for sugar groups that are part of other molecules, so cause agglutination of particular cells or precipitation of glycoconjugates and polysaccharides. Lectins have a role in recognition at the cellular and molecular level and play numerous roles in biological recognition phenomena involving cells, carbohydrates, and proteins. Lectins also mediate attachment and binding of bacteria, viruses, and fungi to their intended targets. Lectins are ubiquitous in nature and are found in many foods. Some foods, such as beans and grains, need to be cooked, fermented or sprouted to reduce lectin content. Some lectins are beneficial, such as CLEC11A, which promotes bone growth, while others may be powerful toxins such as ricin. Lectins may be disabled by specific mono- and oligosaccharides, which bind to ingested lectins from grains, legumes, nightshade plants, and dairy; binding can prevent their attachment to the carbohy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fabaceae
The Fabaceae or Leguminosae,International Code of Nomenclature for algae, fungi, and plants. Article 18.5 states: "The following names, of long usage, are treated as validly published: ....Leguminosae (nom. alt.: Fabaceae; type: Faba Mill. Vicia L.; ... When the Papilionaceae are regarded as a family distinct from the remainder of the Leguminosae, the name Papilionaceae is conserved against Leguminosae." English pronunciations are as follows: , and . commonly known as the legume, pea, or bean family, are a large and agriculturally important of |
Phytohemagglutinin
Phytohaemagglutinin (PHA, or phytohemagglutinin) is a lectin found in plants, especially certain legumes. PHA actually consists of two closely related proteins, called leucoagglutinin (PHA-L) and PHA-E. These proteins cause blood cells to clump together. PHA-E cause erythrocytes (red blood cells) to clump. PHA-L causes leukocytes (white blood cells) to clump. Phytohaemagglutinin has carbohydrate-binding specificity for a complex oligosaccharide containing galactose, ''N''-acetylglucosamine, and mannose. It is found in the highest concentrations in uncooked red kidney beans and white kidney beans (also known as cannellini), and it is also found in lower quantities in many other types of green beans and other common beans (''Phaseolus vulgaris''), as well as broad beans (''Vicia faba'') such as fava beans. It has a number of physiological effects and is used in medical research. In high doses, it is a toxin. The lectin has a number of effects on cell metabolism; it induces mitosi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Concanavalin A
Concanavalin A (ConA) is a lectin (carbohydrate-binding protein) originally extracted from the jack-bean (''Canavalia ensiformis''). It is a member of the legume lectin family. It binds specifically to certain structures found in various sugars, glycoproteins, and glycolipids, mainly internal and nonreducing terminal α-D- mannosyl and α-D-glucosyl groups. Its physiological function in plants, however, is still unknown. ConA is a plant mitogen, and is known for its ability to stimulate mouse T-cell subsets giving rise to four functionally distinct T cell populations, including precursors to regulatory T cells; a subset of human suppressor T-cells is also sensitive to ConA. ConA was the first lectin to be available on a commercial basis, and is widely used in biology and biochemistry to characterize glycoproteins and other sugar-containing entities on the surface of various cells. It is also used to purify glycosylated macromolecules in lectin affinity chromatography, as well as t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Legume Lectin Monomer
A legume () is a plant in the family Fabaceae (or Leguminosae), or the fruit or seed of such a plant. When used as a dry grain, the seed is also called a pulse. Legumes are grown agriculturally, primarily for human consumption, for livestock forage and silage, and as soil-enhancing green manure. Well-known legumes include beans, soybeans, chickpeas, peanuts, lentils, lupins, mesquite, carob, tamarind, alfalfa, and clover. Legumes produce a botanically unique type of fruit – a simple dry fruit that develops from a simple carpel and usually dehisces (opens along a seam) on two sides. Legumes are notable in that most of them have symbiotic nitrogen-fixing bacteria in structures called root nodules. For that reason, they play a key role in crop rotation. Terminology The term ''pulse'', as used by the United Nations' Food and Agriculture Organization (FAO), is reserved for legume crops harvested solely for the dry seed. This excludes green beans and green peas, which are consid ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
