Lactase Persistence
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Lactase Persistence
Lactase persistence is the continued activity of the lactase enzyme in adulthood, allowing the digestion of lactose in milk. In most mammals, the activity of the enzyme is dramatically reduced after weaning. In some human populations, though, lactase persistence has recently evolved as an adaptation to the consumption of nonhuman milk and dairy products beyond infancy. Lactase persistence is very high among northern Europeans, especially Irish people. Worldwide, most people are lactase ''non''-persistent, and are affected by varying degrees of lactose intolerance as adults. However, lactase persistence and lactose intolerance do not always overlap. Global distribution of the phenotype The distribution of the lactase persistence (LP) phenotype, or the ability to digest lactose into adulthood, is not homogeneous in the world. Lactase persistence frequencies are highly variable. In Europe, the distribution of the lactase persistence phenotype is clinal, with frequencies ranging from ...
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Lactase
Lactase is an enzyme produced by many organisms. It is located in the brush border of the small intestine of humans and other mammals. Lactase is essential to the complete digestion of whole milk; it breaks down lactose, a sugar which gives milk its sweetness. People who have deficiency of lactase, and consume dairy products, may experience the symptoms of lactose intolerance. Lactase can be purchased as a food supplement, and is added to milk to produce "lactose-free" milk products. Lactase (also known as lactase-phlorizin hydrolase, or LPH), a part of the β-galactosidase family of enzymes, is a glycoside hydrolase involved in the hydrolysis of the disaccharide lactose into constituent galactose and glucose monomers. Lactase is present predominantly along the brush border membrane of the differentiated enterocytes lining the villi of the small intestine. In humans, lactase is encoded by the LCT gene on chromosome 2. Uses Food use Lactase is an enzyme that some people are ...
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Haryana
Haryana (; ) is an Indian state located in the northern part of the country. It was carved out of the former state of East Punjab on 1 Nov 1966 on a linguistic basis. It is ranked 21st in terms of area, with less than 1.4% () of India's land area. The state capital is Chandigarh, which it shares with the neighboring state of Punjab, and the most populous city is Faridabad, which is a part of the National Capital Region (India), National Capital Region. The city of Gurugram is among India's largest financial and technology hubs. Haryana has 6 Divisions of Haryana, administrative divisions, 22 List of districts of Haryana, districts, 72 sub-divisions, 93 tehsil, revenue tehsils, 50 sub-tehsils, 140 Community development block in India, community development blocks, 154 List of cities in Haryana by population, cities and towns, 7,356 villages, and 6,222 Gram panchayat, villages panchayats. Haryana contains 32 special economic zones (SEZs), mainly located within the industrial corri ...
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Lactase
Lactase is an enzyme produced by many organisms. It is located in the brush border of the small intestine of humans and other mammals. Lactase is essential to the complete digestion of whole milk; it breaks down lactose, a sugar which gives milk its sweetness. People who have deficiency of lactase, and consume dairy products, may experience the symptoms of lactose intolerance. Lactase can be purchased as a food supplement, and is added to milk to produce "lactose-free" milk products. Lactase (also known as lactase-phlorizin hydrolase, or LPH), a part of the β-galactosidase family of enzymes, is a glycoside hydrolase involved in the hydrolysis of the disaccharide lactose into constituent galactose and glucose monomers. Lactase is present predominantly along the brush border membrane of the differentiated enterocytes lining the villi of the small intestine. In humans, lactase is encoded by the LCT gene on chromosome 2. Uses Food use Lactase is an enzyme that some people are ...
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MRNA
In molecular biology, messenger ribonucleic acid (mRNA) is a single-stranded molecule of RNA that corresponds to the genetic sequence of a gene, and is read by a ribosome in the process of Protein biosynthesis, synthesizing a protein. mRNA is created during the process of Transcription (biology), transcription, where an enzyme (RNA polymerase) converts the gene into primary transcript mRNA (also known as pre-mRNA). This pre-mRNA usually still contains introns, regions that will not go on to code for the final amino acid sequence. These are removed in the process of RNA splicing, leaving only exons, regions that will encode the protein. This exon sequence constitutes mature mRNA. Mature mRNA is then read by the ribosome, and, utilising amino acids carried by transfer RNA (tRNA), the ribosome creates the protein. This process is known as Translation (biology), translation. All of these processes form part of the central dogma of molecular biology, which describes the flow of genet ...
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Hypolactasia
Lactose intolerance is a common condition caused by a decreased ability to digest lactose, a sugar found in dairy products. Those affected vary in the amount of lactose they can tolerate before symptoms develop. Symptoms may include abdominal pain, bloating, diarrhea, flatulence, and nausea. These symptoms typically start thirty minutes to two hours after eating or drinking milk-based food. Their severity typically depends on the amount a person eats or drinks. Lactose intolerance does not cause damage to the gastrointestinal tract. Lactose intolerance is due to the lack of the enzyme lactase in the small intestines to break lactose down into glucose and galactose. There are four types: primary, secondary, developmental, and congenital. Primary lactose intolerance occurs as the amount of lactase declines as people age. Secondary lactose intolerance is due to injury to the small intestine. Such injury could be the result of infection, celiac disease, inflammatory bowel d ...
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Lactase Persistence In The Old World
Lactase is an enzyme produced by many organisms. It is located in the brush border of the small intestine of humans and other mammals. Lactase is essential to the complete digestion of whole milk; it breaks down lactose, a sugar which gives milk its sweetness. People who have deficiency of lactase, and consume dairy products, may experience the symptoms of lactose intolerance. Lactase can be purchased as a food supplement, and is added to milk to produce "lactose-free" milk products. Lactase (also known as lactase-phlorizin hydrolase, or LPH), a part of the β-galactosidase family of enzymes, is a glycoside hydrolase involved in the hydrolysis of the disaccharide lactose into constituent galactose and glucose monomers. Lactase is present predominantly along the brush border membrane of the differentiated enterocytes lining the villi of the small intestine. In humans, lactase is encoded by the LCT gene on chromosome 2. Uses Food use Lactase is an enzyme that s ...
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Amasi
Amasi (in Zulu and Xhosa), maas (in Afrikaans), or mafi (in Sesotho), is a fermented milk product that is similar to cottage cheese or plain yogurt. It is a popular snack in South Africa and Lesotho. Preparation Amasi is traditionally prepared by storing unpasteurised cow's milk in a calabash container ( ) or hide sack to allow it to ferment. The fermenting milk develops a watery substance called ''umlaza''; the remainder is amasi. This thick liquid is mostly poured over mealie meal porridge called pap. (), It is traditionally served in a clay pot () and eaten with wooden spoons, but it can also be drunk. I. Amasi is also produced commercially using ''Lactococcus lactis'', along with subspecies of L. lactis. In culture Zulu Traditionally, Zulus believe that amasi makes a man strong, healthy, and desired. During "taboos", such as periods during menstruation or when a person has been in contact with death, the affected person must abstain from amasi. Milk is hardly e ...
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Nguni People
The Nguni people are a Bantu ethnic group from South Africa, with off-shoots in neighbouring countries in Southern Africa. Swazi (or Swati) people live in both South Africa and Eswatini, while Northern Ndebele people live in both South Africa (as immigrants) and Zimbabwe. A group of the Nguni living in present day Malawi and Zambia originated from South Africa and are known as AbaNgoni (or Ngoni/Nguni). The name AbaNgoni can be translated to "People who doesn't commit sins". Both the Ndebele of Zimbabwe and the Ngoni migrated northwards out of South Africa in the early 19th century, during a politically tumultuous era that included the so-called Mfecane and Great Trek. In South Africa, the historic Nguni kingdoms of the Ndebele, Swazi, Xhosa and Zulu are in the present-day provinces of Southern and Eastern Cape, Gauteng, KwaZulu-Natal, Limpopo and Mpumalanga. The most notable of these kingdoms are the Zulu Kingdom, which was ruled by Shaka, a warrior king whose conquest took ...
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Bedouin
The Bedouin, Beduin, or Bedu (; , singular ) are nomadic Arab tribes who have historically inhabited the desert regions in the Arabian Peninsula, North Africa, the Levant, and Mesopotamia. The Bedouin originated in the Syrian Desert and Arabian Desert but spread across the rest of the Arab world in West Asia and North Africa after the spread of Islam. The English word ''bedouin'' comes from the Arabic ''badawī'', which means "desert dweller", and is traditionally contrasted with ''ḥāḍir'', the term for sedentary people. Bedouin territory stretches from the vast deserts of North Africa to the rocky sands of the Middle East. They are traditionally divided into tribes, or clans (known in Arabic as ''ʿašāʾir''; or ''qabāʾil'' ), and historically share a common culture of herding camels and goats. The vast majority of Bedouins adhere to Islam, although there are some fewer numbers of Christian Bedouins present in the Fertile Crescent. Bedouins have been referred ...
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Fulani
The Fula, Fulani, or Fulɓe people ( ff, Fulɓe, ; french: Peul, links=no; ha, Fulani or Hilani; pt, Fula, links=no; wo, Pël; bm, Fulaw) are one of the largest ethnic groups in the Sahel and West Africa, widely dispersed across the region. Inhabiting many countries, they live mainly in West Africa and northern parts of Central Africa, South Sudan, Darfur, and regions near the Red Sea coast in Sudan. The approximate number of Fula people is unknown due to clashing definitions regarding Fula ethnicity. Various estimates put the figure between 25 and 40 million people worldwide. A significant proportion of the Fula – a third, or an estimated 12 to 13 million – are pastoralists, and their ethnic group has the largest nomadic pastoral community in the world., Quote: The Fulani form the largest pastoral nomadic group in the world. The Bororo'en are noted for the size of their cattle herds. In addition to fully nomadic groups, however, there are also semisedentary Fulani —F ...
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Pastoralism
Pastoralism is a form of animal husbandry where domesticated animals (known as "livestock") are released onto large vegetated outdoor lands (pastures) for grazing, historically by nomadic people who moved around with their herds. The animal species involved include cattle, camels, goats, yaks, llamas, reindeer, horses and sheep. Pastoralism occurs in many variations throughout the world, generally where environmental characteristics such as aridity, poor soils, cold or hot temperatures, and lack of water make crop-growing difficult or impossible. Operating in more extreme environments with more marginal lands means that pastoral communities are very vulnerable to the effects of global warming. Pastoralism remains a way of life in many geographic areas, including Africa, the Tibetan plateau, the Eurasian steppes, the Andes, Patagonia, the Pampas, Australia and many other places. , between 200 million and 500 million people globally practised pastoralism, and 75% ...
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Nilotes
The Nilotic peoples are people indigenous to the Nile Valley who speak Nilotic languages. They inhabit South Sudan, Sudan, Ethiopia, Uganda, Kenya, the Democratic Republic of the Congo, Rwanda, Burundi and Tanzania. Among these are the Burun-speaking peoples, Karo peoples, Luo peoples, Ateker peoples, Kalenjin peoples, Datooga, Dinka, Nuer, Atwot, Lotuko, and the Maa-speaking peoples. The Nilotes constitute the majority of the population in South Sudan, an area that is believed to be their original point of dispersal. After the Bantu peoples, they constitute the second-most numerous group of peoples inhabiting the African Great Lakes region around the East African Rift. They make up a notable part of the population of southwestern Ethiopia as well. The Nilotic peoples primarily adhere to Christianity and traditional faiths, including the Dinka religion. Some Nilotic peoples also adhere to Islam. Name The terms "Nilotic" and "Nilote"' were previously used as racial subcla ...
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