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Liver Fluke
Liver fluke is a collective name of a polyphyletic group of parasitic trematodes under the phylum Platyhelminthes. They are principally parasites of the liver of various mammals, including humans. Capable of moving along the blood circulation, they can occur also in bile ducts, gallbladder, and liver parenchyma. In these organs, they produce pathological lesions leading to parasitic diseases. They have complex life cycles requiring two or three different hosts, with free-living larval stages in water. Biology The body of liver flukes is leaf-like and flattened. The body is covered with a tegument. They are hermaphrodites having complete sets of both male and female reproductive systems. They have simple digestive systems and primarily feed on blood. The anterior end is the oral sucker opening into the mouth. Inside, the mouth leads to a small pharynx which is followed by an extended intestine that runs through the entire length of the body. The intestine is heavily branched and t ...
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Metorchis Conjunctus
''Metorchis conjunctus'', common name Canadian liver fluke, is a species of trematode parasite in the family Opisthorchiidae. It can infect mammals that eat raw fish in North America. The first intermediate host is a freshwater snail and the second is a freshwater fish. Taxonomy This species was discovered and described by Thomas Spencer Cobbold in 1860. Distribution The distribution of ''M. conjunctus'' includes: * East Greenland * From Quebec to Saskatchewan * Maine, Connecticut, South Carolina, US Description The body of ''M. conjunctus'' is pear-shaped and flat. The body length is . It has a weakly muscular terminal oral sucker. No prepharynx is present. The pharynx is strongly muscular. The esophagus is very short. The intestinal ceca vary from almost straight to sinuous. The acetabulum is slightly oval and weakly muscular. The male has an anterior testis and a posterior testis. The testes vary from almost round to oval, and may be deeply lobed or slightly indented. ...
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Fascioloides Magna
''Fascioloides magna'', also known as giant liver fluke, large American liver fluke or deer fluke, is trematode parasite that occurs in wild and domestic ruminants in North America and Europe. Adult flukes occur in the liver of the definitive host and feed on blood. Mature flukes measure in length × in width, and have an oval dorso-ventrally flattened body with oral and ventral sucker. The flukes are reddish-brown in colour and are covered by tegument. As with other digenean trematodes, the life cycle includes intramolluscan phase in snails.Erhardová-Kotrlá, B., 1971. The occurrence of ''Fascioloides magna'' (Bassi, 1875) in Czechoslovakia. Academia, Prague, 155 pp.Pybus, M.J., 2001. Liver flukes. In: Samuel, W.M., Pybus, M.J., Kocan, A.A. (eds.), Parasitic diseases in wild mammals, Iowa State Press, Iowa City, pp 121–149. The parasite is currently distributed in wild ruminants in North America and Europe, including Austria, Canada, the Czech Republic, Croatia, Germany, Hun ...
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Fasciola Hepatica
''Fasciola hepatica'', also known as the common liver fluke or sheep liver fluke, is a parasitic trematode (fluke or flatworm, a type of helminth) of the class Trematoda, phylum Platyhelminthes. It infects the livers of various mammals, including humans, and is transmitted by sheep and cattle to humans the world over. The disease caused by the fluke is called fasciolosis or fascioliasis, which is a type of helminthiasis and has been classified as a neglected tropical disease. Fasciolosis is currently classified as a plant/food-borne trematode infection, often acquired through eating the parasite's metacercariae encysted on plants. ''F. hepatica'', which is distributed worldwide, has been known as an important parasite of sheep and cattle for decades and causes significant economic losses in these livestock species, up to £23 million in the UK alone. Because of its relatively large size and economic importance, it has been the subject of many scientific investigations and may ...
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Opisthorchis Viverrini
''Opisthorchis viverrini'', common name Southeast Asian liver fluke, is a food-borne trematode parasite from the family Opisthorchiidae that infects the bile duct. People are infected after eating raw or undercooked fish. Infection with the parasite is called opisthorchiasis. ''O. viverrini'' infection also increases the risk of cholangiocarcinoma, a cancer of the bile ducts. A small, leaf-like fluke, ''O. viverrini'' completes its lifecycle in three different animals. Snails of the species ''Bithynia'' are the first intermediate hosts, fish belonging to the family Cyprinidae are the second intermediate host, and the definitive hosts are humans and other mammals such as dogs, cats, rats, and pigs. It was first discovered in the Indian fishing cat (''Prionailurus viverrus'') by M.J. Poirier in 1886. The first human case was discovered by Robert Thomson Leiper in 1915. ''O. viverrini'' (together with ''Clonorchis sinensis'' and ''Opisthorchis felineus'') is one of the three mos ...
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Fasciola Jacksoni
Fasciolidae is a family of trematodes and includes several parasites involved in the veterinary and medical sciences, which cause the disease Fasciolosis. Fasciolidae is divided into five genera by Olson et al. 2003. The family's various species are localised in liver, gall bladder, and intestine. Their life-cycle includes an intermediate host, freshwater snails from the family Lymnaeidae.Jurášek, V., Dubinský, P., 1993. Veterinárna parazitológia. Príroda a.s., Bratislava, 382 pp. Morphology Adult trematodes of Fasciolidae range in length from 2 cm, for species of ''Parafasciolopsis'', and 10 cm, for species such as ''Fasciola gigantica''. The oral and ventral suckers are usually located. the cercariae are of a gymnocephalic shape. Systematics within family According to Olson ''et al.'' 2003 Olson, P.D., Cribb, T.H., Tkach, V.V., Bray, R.A., Littlewood, D.T.J., 2003. Phylogeny and classification of the Digenea (Platyhelminthes: Trematoda)1. Int. J. Parasitol. 22 ...
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Fasciola Gigantica
''Fasciola gigantica'' is a parasitic flatworm of the class Trematoda, which causes tropical fascioliasis. It is regarded as one of the most important single platyhelminth infections of ruminants in Asia and Africa. Estimates of infection rates are as high as 80–100% in some countries. The infection is commonly called fasciolosis. The prevalence of ''F. gigantica'' often overlaps with that of ''Fasciola hepatica'', and the two species are so closely related in terms of genetics, behaviour, and morphological and anatomical structures that distinguishing them is notoriously difficult. Therefore, sophisticated molecular techniques are required to correctly identify and diagnose the infection. Distribution ''Fasciola gigantica'' causes outbreaks in tropical areas of South Asia, Southeast Asia, and Africa. The geographical distribution of ''F. gigantica'' overlaps with ''F. hepatica'' in many African and Asian countries and sometimes in the same country, although in such cases, ...
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Dicrocoelium Hospes
''Dicrocoelium hospes'' is a species of flatworms belonging to the family Dicrocoeliidae. The species may cause the disease dicrocoeliasis ''Dicrocoelium dendriticum'', the lancet liver fluke, is a parasite fluke that tends to live in cattle or other grazing mammals. History of discovery Much of what is presently known about ''Dicrocoelium dendriticum'' is the result of the wor .... References Plagiorchiida Animals described in 1907 {{Trematoda-stub ...
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Dicrocoelium Dendriticum
''Dicrocoelium dendriticum'', the lancet liver fluke, is a parasite fluke that tends to live in cattle or other grazing mammals. History of discovery Much of what is presently known about ''Dicrocoelium dendriticum'' is the result of the work of the naturalist Wendell Krull. While ''D. dendriticum'' was discovered by Rudolphi in 1819 and ''D. hospes'' was discovered by Loos in 1899, the full life cycle was not known until Krull and C.R. Mapes published a series of papers from 1951-1953 detailing their observations and experiments. It was known that ''D. dendriticum'' affected sheep, but everything else was a mystery. The first link in the chain was the discovery of the first intermediate host, the land snail ''Cochlicopa lubrica'' (synonym: ''Cionella lubrica''). Next came the discovery that the slime balls coughed up by the snails could be a potential method of transfer of the parasite. Shortly thereafter, the ant ''Formica fusca'' was found to be the second intermediate ...
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IARC Group 1
Substances, mixtures, and exposure circumstances in this list have been classified as group 1 by the International Agency for Research on Cancer (IARC): The agent (mixture) is carcinogenic to humans. The exposure circumstance entails exposures that are carcinogenic to humans. This category is used when there is sufficient evidence of carcinogenicity in humans. Exceptionally, an agent (mixture) may be placed in this category when evidence of carcinogenicity in humans is less than sufficient but there is sufficient evidence of carcinogenicity in experimental animals and strong evidence in exposed humans that the agent (mixture) acts through a relevant mechanism of carcinogenicity. Agents Infectious conditions Viruses *Human immunodeficiency virus type 1 (infection with) * Human T-cell lymphotropic virus type I *Human papillomavirus types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, and 59 *Hepatitis B virus (chronic infection with) *Hepatitis C virus (chronic infection with) * Ka ...
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International Agency For Research On Cancer
The International Agency for Research on Cancer (IARC; french: Centre International de Recherche sur le Cancer, CIRC) is an intergovernmental agency forming part of the World Health Organization of the United Nations. Its role is to conduct and coordinate research into the causes of cancer. It also collects and publishes surveillance data regarding the occurrence of cancer worldwide. Its IARC monographs programme identifies carcinogenic hazards and evaluates environmental causes of cancer in humans. IARC has its own governing council, and in 1965 the first members were the Federal Republic of Germany, France, Italy, the United Kingdom, and the United States of America. Today, IARC's membership has grown to 27 countries. History In late February 1963, after he experienced his spouse suffering and dying of cancer, journalist and peace activist Yves Poggioli sent a letter to Emmanuel d'Astier de la Vignerie relating his story, and urging support for the creation of an intern ...
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Clonorchis Sinensis
''Clonorchis sinensis'', the Chinese liver fluke, is a liver fluke belonging to the class Trematoda, phylum Platyhelminthes. It infects fish-eating mammals, including humans. In humans, it infects the common bile duct and gall bladder, feeding on bile. It was discovered by British physician James McConnell at the Medical College Hospital in Calcutta (Kolkata) in 1874. The first description was given by Thomas Spencer Cobbold, who named it ''Distoma sinense''. The fluke passes its lifecycle in three different hosts, namely freshwater snail as first intermediate hosts, freshwater fish as second intermediate host, and mammals as definitive hosts. Endemic to Asia and Russia, ''C. sinensis'' is the most prevalent human fluke in Asia and third-most in the world. It is still actively transmitted in Korea, China, Vietnam, and Russia. Most infections (about 85%) occur in China. The infection, called clonorchiasis, generally appears as jaundice, indigestion, biliary inflammation, bile duct ...
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Laos
Laos (, ''Lāo'' )), officially the Lao People's Democratic Republic ( Lao: ສາທາລະນະລັດ ປະຊາທິປະໄຕ ປະຊາຊົນລາວ, French: République démocratique populaire lao), is a socialist state and the only landlocked country in Southeast Asia. At the heart of the Indochinese Peninsula, Laos is bordered by Myanmar and China to the northwest, Vietnam to the east, Cambodia to the southeast, and Thailand to the west and southwest. Its capital and largest city is Vientiane. Present-day Laos traces its historic and cultural identity to Lan Xang, which existed from the 14th century to the 18th century as one of the largest kingdoms in Southeast Asia. Because of its central geographical location in Southeast Asia, the kingdom became a hub for overland trade and became wealthy economically and culturally. After a period of internal conflict, Lan Xang broke into three separate kingdoms: Luang Phrabang, Vientiane and Champasak. In ...
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