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Opisthorchis Viverrini
''Opisthorchis viverrini'', common name Southeast Asian liver fluke, is a food-borne trematode parasite from the family Opisthorchiidae that infects the bile duct. People are infected after eating raw or undercooked fish. Infection with the parasite is called opisthorchiasis. ''O. viverrini'' infection also increases the risk of cholangiocarcinoma, a cancer of the bile ducts. A small, leaf-like fluke, ''O. viverrini'' completes its lifecycle in three different animals. Snails of the species ''Bithynia'' are the first intermediate hosts, fish belonging to the family Cyprinidae are the second intermediate host, and the definitive hosts are humans and other mammals such as dogs, cats, rats, and pigs. It was first discovered in the Indian fishing cat (''Prionailurus viverrus'') by M.J. Poirier in 1886. The first human case was discovered by Robert Thomson Leiper in 1915. ''O. viverrini'' (together with ''Clonorchis sinensis'' and ''Opisthorchis felineus'') is one of the three mos ...
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Oral Sucker
A sucker in zoology refers to a specialised attachment organ of an animal. It acts as an adhesion device in parasitic worms, several flatworms, cephalopods, certain fishes, amphibians, and bats. It is a muscular structure for suction on a host or substrate. In parasitic annelids, flatworms and roundworms, suckers are the organs of attachment to the host tissues. In tapeworms and flukes, they are a parasitic adaptation for attachment on the internal tissues of the host, such as intestines and blood vessels. In roundworms and flatworms they serve as attachment between individuals particularly during mating. In annelids, a sucker can be both a functional mouth and a locomotory organ. The structure and number of suckers are often used as basic taxonomic diagnosis between different species, since they are unique in each species. In tapeworms there are two distinct classes of suckers, namely "bothridia" for true suckers, and " bothria" for false suckers. In digeneal flukes there are us ...
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Cyprinidae
Cyprinidae is a family of freshwater fish commonly called the carp or minnow family. It includes the carps, the true minnows, and relatives like the barbs and barbels. Cyprinidae is the largest and most diverse fish family and the largest vertebrate animal family in general with about 3,000 species, of which only 1,270 remain extant, divided into about 370 genera. Cyprinids range from about 12 mm in size to the giant barb (''Catlocarpio siamensis''). By genus and species count, the family makes up more than two-thirds of the ostariophysian order Cypriniformes. The family name is derived from the Greek word ( 'carp'). Biology and ecology Cyprinids are stomachless fish with toothless jaws. Even so, food can be effectively chewed by the gill rakers of the specialized last gill bow. These pharyngeal teeth allow the fish to make chewing motions against a chewing plate formed by a bony process of the skull. The pharyngeal teeth are unique to each species and are used by scient ...
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National Museum Of Natural History (France)
The National Museum of Natural History is a natural history museum administered by the Smithsonian Institution, located on the National Mall in Washington, D.C., United States. It has free admission and is open 364 days a year. In 2021, with 7.1 million visitors, it was the list of most visited museums, eighteenth most visited museum in the world and the second most visited natural history museum in the world after the Natural History Museum, London, Natural History Museum in London."The World's most popular museums", CNN.com, 22 June 2017. Opened in 1910, the museum on the National Mall was one of the first Smithsonian buildings constructed exclusively to hold the national collections and research facilities. The main building has an overall area of with of exhibition and public space and houses over 1,000 employees. The museum's collections contain over 145 million specimens of plants, animals, fossils, minerals, rock (geology), rocks, meteorites, human remains, and human c ...
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Cambodia
Cambodia (; also Kampuchea ; km, កម្ពុជា, UNGEGN: ), officially the Kingdom of Cambodia, is a country located in the southern portion of the Indochinese Peninsula in Southeast Asia, spanning an area of , bordered by Thailand to the northwest, Laos to the north, Vietnam to the east, and the Gulf of Thailand to the southwest. The capital and largest city is Phnom Penh. The sovereign state of Cambodia has a population of over 17 million. Buddhism is enshrined in the constitution as the official state religion, and is practised by more than 97% of the population. Cambodia's minority groups include Vietnamese, Chinese, Chams and 30 hill tribes. Cambodia has a tropical monsoon climate of two seasons, and the country is made up of a central floodplain around the Tonlé Sap lake and Mekong Delta, surrounded by mountainous regions. The capital and largest city is Phnom Penh, the political, economic and cultural centre of Cambodia. The kingdom is an elective co ...
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Vietnam
Vietnam or Viet Nam ( vi, Việt Nam, ), officially the Socialist Republic of Vietnam,., group="n" is a country in Southeast Asia, at the eastern edge of mainland Southeast Asia, with an area of and population of 96 million, making it the world's sixteenth-most populous country. Vietnam borders China to the north, and Laos and Cambodia to the west. It shares maritime borders with Thailand through the Gulf of Thailand, and the Philippines, Indonesia, and Malaysia through the South China Sea. Its capital is Hanoi and its largest city is Ho Chi Minh City (commonly known as Saigon). Vietnam was inhabited by the Paleolithic age, with states established in the first millennium BC on the Red River Delta in modern-day northern Vietnam. The Han dynasty annexed Northern and Central Vietnam under Chinese rule from 111 BC, until the first dynasty emerged in 939. Successive monarchical dynasties absorbed Chinese influences through Confucianism and Buddhism, and expanded ...
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Lao People's Democratic Republic
Laos (, ''Lāo'' )), officially the Lao People's Democratic Republic ( Lao: ສາທາລະນະລັດ ປະຊາທິປະໄຕ ປະຊາຊົນລາວ, French: République démocratique populaire lao), is a socialist state and the only landlocked country in Southeast Asia. At the heart of the Indochinese Peninsula, Laos is bordered by Myanmar and China to the northwest, Vietnam to the east, Cambodia to the southeast, and Thailand to the west and southwest. Its capital and largest city is Vientiane. Present-day Laos traces its historic and cultural identity to Lan Xang, which existed from the 14th century to the 18th century as one of the largest kingdoms in Southeast Asia. Because of its central geographical location in Southeast Asia, the kingdom became a hub for overland trade and became wealthy economically and culturally. After a period of internal conflict, Lan Xang broke into three separate kingdoms: Luang Phrabang, Vientiane and Champasak. In ...
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Thailand
Thailand ( ), historically known as Siam () and officially the Kingdom of Thailand, is a country in Southeast Asia, located at the centre of the Indochinese Peninsula, spanning , with a population of almost 70 million. The country is bordered to the north by Myanmar and Laos, to the east by Laos and Cambodia, to the south by the Gulf of Thailand and Malaysia, and to the west by the Andaman Sea and the extremity of Myanmar. Thailand also shares maritime borders with Vietnam to the southeast, and Indonesia and India to the southwest. Bangkok is the nation's capital and largest city. Tai peoples migrated from southwestern China to mainland Southeast Asia from the 11th century. Indianised kingdoms such as the Mon, Khmer Empire and Malay states ruled the region, competing with Thai states such as the Kingdoms of Ngoenyang, Sukhothai, Lan Na and Ayutthaya, which also rivalled each other. European contact began in 1511 with a Portuguese diplomatic mission to Ayutthaya, w ...
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Carcinogen
A carcinogen is any substance, radionuclide, or radiation that promotes carcinogenesis (the formation of cancer). This may be due to the ability to damage the genome or to the disruption of cellular metabolic processes. Several radioactive substances are considered carcinogens, but their carcinogenic activity is attributed to the radiation, for example gamma rays and alpha particles, which they emit. Common examples of non-radioactive carcinogens are inhaled asbestos, certain dioxins, and tobacco smoke. Although the public generally associates carcinogenicity with synthetic chemicals, it is equally likely to arise from both natural and synthetic substances. Carcinogens are not necessarily immediately toxic; thus, their effect can be insidious. Carcinogens, as mentioned, are agents in the environment capable of contributing to cancer growth. Carcinogens can be categorized into two different types: activation-dependent and activation-independent, and each nature impacts their level ...
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List Of IARC Group 1 Carcinogens
Substances, mixtures, and exposure circumstances in this list have been classified as group 1 by the International Agency for Research on Cancer (IARC): The agent (mixture) is carcinogenic to humans. The exposure circumstance entails exposures that are carcinogenic to humans. This category is used when there is sufficient evidence of carcinogenicity in humans. Exceptionally, an agent (mixture) may be placed in this category when evidence of carcinogenicity in humans is less than sufficient but there is sufficient evidence of carcinogenicity in experimental animals and strong evidence in exposed humans that the agent (mixture) acts through a relevant mechanism of carcinogenicity. Agents Infectious conditions Viruses *Human immunodeficiency virus type 1 (infection with) * Human T-cell lymphotropic virus type I *Human papillomavirus types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, and 59 *Hepatitis B virus (chronic infection with) *Hepatitis C virus (chronic infection with) * Ka ...
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International Agency For Research On Cancer
The International Agency for Research on Cancer (IARC; french: Centre International de Recherche sur le Cancer, CIRC) is an intergovernmental agency forming part of the World Health Organization of the United Nations. Its role is to conduct and coordinate research into the causes of cancer. It also collects and publishes surveillance data regarding the occurrence of cancer worldwide. Its IARC monographs programme identifies carcinogenic hazards and evaluates environmental causes of cancer in humans. IARC has its own governing council, and in 1965 the first members were the Federal Republic of Germany, France, Italy, the United Kingdom, and the United States of America. Today, IARC's membership has grown to 27 countries. History In late February 1963, after he experienced his spouse suffering and dying of cancer, journalist and peace activist Yves Poggioli sent a letter to Emmanuel d'Astier de la Vignerie relating his story, and urging support for the creation of an intern ...
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Carcinogenic Parasite
Carcinogenic parasites are parasitic organisms that depend on other organisms (called hosts) for their survival, and cause cancer in such hosts. Three species of flukes (trematodes) are medically-proven carcinogenic parasites, namely the urinary blood fluke (''Schistosoma haematobium''), the Southeast Asian liver fluke (''Opisthorchis viverrini'') and the Chinese liver fluke (''Clonorchis sinensis''). ''S. haematobium'' is prevalent in Africa and the Middle East, and is the leading cause of bladder cancer (only next to tobacco smoking). ''O. viverrini'' and ''C. sinensis'' are both found in eastern and southeastern Asia, and are responsible for cholangiocarcinoma (cancer of the bile ducts). The International Agency for Research on Cancer declared them in 2009 as a Group 1 biological carcinogens in humans. Other parasites are also linked to various cancers. Among protozoan parasites, ''Toxoplasma gondii'', ''Cryptosporidium parvum'', ''Trichomonas vaginalis'' and ''Theileria'' ar ...
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Opisthorchis Felineus
''Opisthorchis felineus'', or cat liver fluke is a trematode parasite that infects the liver in mammals. It was first discovered in 1884 in a cat's liver by Sebastiano Rivolta of Italy. In 1891, Russian parasitologist, Konstantin Nikolaevich Vinogradov (1847–1906) found it in a human, and named the parasite a "Siberian liver fluke". In the 1930s, helminthologist Hans Vogel of Hamburg published an article describing the life cycle of ''Opisthorchis felineus''.
Bernhard Nocht Institute for Tropical Medicine Felineus infections may also involve the pancreatic ducts. Diagnosis of Opisthorchis infection is based on microscopic identification of parasite eggs in stool specimens. Safe and effective medication is available to treat Opisthorchis infections. Adequately freezing or cook ...
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