Gammaherpesvirus
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Gammaherpesvirus
''Gammaherpesvirinae'' is a subfamily of viruses in the order ''Herpesvirales'' and in the family ''Herpesviridae''. Viruses in ''Gammaherpesvirinae'' are distinguished by reproducing at a more variable rate than other subfamilies of ''Herpesviridae''. Mammals serve as natural hosts. There are 43 species in this subfamily, divided among 7 genera with three species unassigned to a genus. Diseases associated with this subfamily include: HHV-4: infectious mononucleosis. HHV-8: Kaposi's sarcoma. Taxonomy Herpesviruses represent a group of double-stranded DNA viruses distributed widely within the animal kingdom. The family ''Herpesviridae'', which contains eight viruses that infect humans, is the most extensively studied group within this order and comprises three subfamilies, namely ''Alphaherpesvirinae'', ''Betaherpesvirinae'' and ''Gammaherpesvirinae''. Within the ''Gammaherpesvirinae'' there are a number of unclassified viruses including ''Cynomys herpesvirus 1'' (CynGHV-1)Nag ...
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Rhadinovirus
''Rhadinovirus'' (synonyms: ''Rhadinoviridae'' and gamma-2 herpesviruses) is a genus of viruses in the order ''Herpesvirales'', in the family ''Herpesviridae'', in the subfamily ''Gammaherpesvirinae''. Humans and other mammals serve as natural hosts. There are 12 species in this genus. Diseases associated with this genus include: Kaposi's sarcoma, primary effusion lymphoma and multicentric Castleman's disease, caused by '' Human gammaherpesvirus 8'' (HHV-8), also known as Kaposi's sarcoma-associated herpesvirus (KSHV). The term rhadino comes from the Latin fragile, referring to the tendency of the viral genome to break apart when it is isolated. Species The genus consists of the following 12 species: * '' Ateline gammaherpesvirus 2'' * '' Ateline gammaherpesvirus 3'' * '' Bovine gammaherpesvirus 4'' * '' Cricetid gammaherpesvirus 2'' * '' Human gammaherpesvirus 8'' * '' Macacine gammaherpesvirus 5'' * '' Macacine gammaherpesvirus 8'' * '' Macacine gammaherpesvirus 11'' * '' Ma ...
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Lymphocryptovirus
''Lymphocryptovirus'' is a genus of viruses in the order ''Herpesvirales'', in the family ''Herpesviridae'', in the subfamily ''Gammaherpesvirinae''. This genus includes the human-infecting ''Human gammaherpesvirus 4'' (Epstein–Barr virus), as well as viruses that infect both Old World monkeys and New World monkeys. Other names for the ''Lymphocryptovirus'' genus include ''Lymphocryptoviridae'' (suffix -''viridae'' implying family rank, although this is not the accepted taxonomy) and gamma-1 herpesviruses. There are nine species in this genus. Diseases associated with this genus include: mononucleosis, Burkitt's lymphoma, and nasopharyngeal carcinoma. Species The genus consists of the following nine species: * ''Callitrichine gammaherpesvirus 3'' * ''Cercopithecine gammaherpesvirus 14'' * ''Gorilline gammaherpesvirus 1'' * ''Human gammaherpesvirus 4'' * ''Macacine gammaherpesvirus 4'' * ''Macacine gammaherpesvirus 10'' * ''Panine gammaherpesvirus 1'' * ''Papiine gammaherpesv ...
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Macavirus
''Macavirus'' is a genus of viruses in the order ''Herpesvirales'', in the family ''Herpesviridae'', in the subfamily ''Gammaherpesvirinae''. Mammals serve as natural hosts. There are nine species in this genus. Diseases associated with this genus include: inapparent infection in their reservoir hosts (wildebeest for alHV-1 and sheep for ovHV-2), but fatal lymphoproliferative disease when they infect MCF-susceptible hosts, including cattle, deer, bison, water buffalo and pigs. Species The genus consists of the following nine species: * ''Alcelaphine gammaherpesvirus 1'' * ''Alcelaphine gammaherpesvirus 2'' * ''Bovine gammaherpesvirus 6'' * ''Caprine gammaherpesvirus 2'' * ''Hippotragine gammaherpesvirus 1'' * ''Ovine gammaherpesvirus 2'' * ''Suid gammaherpesvirus 3'' * ''Suid gammaherpesvirus 4'' * ''Suid gammaherpesvirus 5 ''Suid gammaherpesvirus 5'' (SuHV-5) is a species of virus in the genus ''Macavirus'', subfamily ''Gammaherpesvirinae'', family ''Herpesviridae'', and o ...
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Percavirus
''Percavirus'' is a genus of viruses in the order ''Herpesvirales'', in the family ''Herpesviridae'', in the subfamily ''Gammaherpesvirinae''. Mammals serve as natural hosts. There are six species in this genus. Diseases associated with this genus include: conjunctivitis, immunosuppression Immunosuppression is a reduction of the activation or efficacy of the immune system. Some portions of the immune system itself have immunosuppressive effects on other parts of the immune system, and immunosuppression may occur as an adverse react ... in foals, pneumonia, respiratory disease. Species The genus consists of the following six species: * '' Equid gammaherpesvirus 2'' * '' Equid gammaherpesvirus 5'' * '' Felid gammaherpesvirus 1'' * '' Mustelid gammaherpesvirus 1'' * '' Phocid gammaherpesvirus 3'' * '' Vespertilionid gammaherpesvirus 1'' Structure Viruses in ''Percavirus'' are enveloped, with icosahedral, spherical to pleomorphic, and round geometries, and T=16 symmetry. The ...
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Phocid Gammaherpesvirus 2
''Phocid gammaherpesvirus 2'' (PhHV-2) is a species of virus of uncertain generic placement in the subfamily ''Gammaherpesvirinae'', family ''Herpesviridae'', and order ''Herpesvirales The ''Herpesvirales'' is an order of dsDNA viruses (Baltimore group I) with animal hosts, characterised by a common morphology consisting of an icosahedral capsid enclosed in a glycoprotein-containing lipid envelope. Common infections in humans c ...''. References External links * Gammaherpesvirinae {{Virus-stub ...
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Equid Gammaherpesvirus 7
''Equid gammaherpesvirus 7'' (EHV-7) is a species of virus of uncertain generic placement in the subfamily ''Gammaherpesvirinae'', family ''Herpesviridae'', and order ''Herpesvirales The ''Herpesvirales'' is an order of dsDNA viruses (Baltimore group I) with animal hosts, characterised by a common morphology consisting of an icosahedral capsid enclosed in a glycoprotein-containing lipid envelope. Common infections in humans c ...''. References External links * Gammaherpesvirinae {{Virus-stub ...
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Saguinine Gammaherpesvirus 1
''Saguinine gammaherpesvirus 1'' (SgHV-1) is a species of virus of uncertain generic placement in the subfamily ''Gammaherpesvirinae'', family ''Herpesviridae'', and order ''Herpesvirales The ''Herpesvirales'' is an order of dsDNA viruses (Baltimore group I) with animal hosts, characterised by a common morphology consisting of an icosahedral capsid enclosed in a glycoprotein-containing lipid envelope. Common infections in humans c ...''. References External links * Gammaherpesvirinae {{Virus-stub ...
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Herpesvirales
The ''Herpesvirales'' is an order of dsDNA viruses (Baltimore group I) with animal hosts, characterised by a common morphology consisting of an icosahedral capsid enclosed in a glycoprotein-containing lipid envelope. Common infections in humans caused by members of this order include cold sores, genital herpes, chickenpox, shingles, and glandular fever. ''Herpesvirales'' is the sole order in the class ''Herviviricetes'', which is the sole class in the phylum ''Peploviricota''. Virology Morphology All members of the order have a virion structure that consists of a DNA core surrounded by an icosahedral capsid composed of 12 pentavalent and 150 hexavalent capsomeres (T = 16). The capsid has a diameter of ~110 nanometers (nm) and is embedded in a proteinaceous matrix called the tegument, which in its turn is enclosed by a glycoprotein-containing lipid envelope with a diameter of about 200 nm. The DNA genome is linear and double stranded, with sizes in the range 125–290 kb ...
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Bossavirus
''Bossavirus'' is a genus of viruses in the subfamily ''Gammaherpesvirinae'', in the family ''Herpesviridae'', in the order ''Herpesvirales The ''Herpesvirales'' is an order of dsDNA viruses (Baltimore group I) with animal hosts, characterised by a common morphology consisting of an icosahedral capsid enclosed in a glycoprotein-containing lipid envelope. Common infections in humans c ....'' It contains the sole species ''Delphinid gammaherpesvirus 1''. References Gammaherpesvirinae Virus genera {{Virus-stub ...
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Manticavirus
''Manticavirus'' is a genus of viruses in the subfamily ''Gammaherpesvirinae'', in the family ''Herpesviridae'', in the order ''Herpesvirales.'' This genus was the only genus to consist entirely of marsupial-hosted species as of the time of naming, hence the name component ''Mantica'' (Latin: ''knapsack''), in reference to the marsupial pouch The pouch is a distinguishing feature of female marsupials, monotremes and possibly most extinct non-placental mammals including eutherians like ''Zalambdalestes'' (and rarely in the males as in the water opossumNogueira, José Carlos, et al.Mor .... Species The genus includes the following species: * '' Phascolarctid gammaherpesvirus 1'' * '' Vombatid gammaherpesvirus 1'' References Gammaherpesvirinae Virus genera {{Virus-stub ...
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Patagivirus
''Patagivirus'' is a genus of viruses in the subfamily ''Gammaherpesvirinae'', in the family ''Herpesviridae'', in the order ''Herpesvirales The ''Herpesvirales'' is an order of dsDNA viruses (Baltimore group I) with animal hosts, characterised by a common morphology consisting of an icosahedral capsid enclosed in a glycoprotein-containing lipid envelope. Common infections in humans c ....'' It contains the sole species ''Vespertilionid gammaherpesvirus 3''. References Gammaherpesvirinae Virus genera {{Virus-stub ...
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Herpesviridae
''Herpesviridae'' is a large family of DNA viruses that cause infections and certain diseases in animals, including humans. The members of this family are also known as herpesviruses. The family name is derived from the Greek word ''ἕρπειν'' ( 'to creep'), referring to spreading cutaneous lesions, usually involving blisters, seen in flares of herpes simplex 1, herpes simplex 2 and herpes zoster ( shingles). In 1971, the International Committee on the Taxonomy of Viruses (ICTV) established ''Herpesvirus'' as a genus with 23 viruses among four groups. As of 2020, 115 species are recognized, all but one of which are in one of the three subfamilies. Herpesviruses can cause both latent and lytic infections. Nine herpesvirus types are known to primarily infect humans, at least five of which – herpes simplex viruses 1 and 2 (HSV-1 and HSV-2, also known as HHV-1 and HHV-2; both of which can cause orolabial herpes and genital herpes), varicella zoster virus (or HHV-3; the cause ...
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