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Glanders
Glanders is a contagious zoonotic infectious disease that occurs primarily in horses, mules, and donkeys. It can be contracted by other animals, such as dogs, cats, pigs, goats, and humans. It is caused by infection with the bacterium ''Burkholderia mallei''. Glanders is endemic in Africa, Asia, the Middle East, and Central and South America. It has been eradicated from North America, Australia, and most of Europe through surveillance and destruction of affected animals, and import restrictions. Glanders has not been reported in the United States since 1945, except in 2000, when an American lab researcher had an accidental exposure in the lab. It is a notifiable disease in the UK, although it has not been reported there since 1928. The term is from Middle English ' or Old French ', both meaning glands. Other terms include la, malleus, es, muermo, german: Rotz and no, snive. Presentation Signs of glanders include the formation of nodular lesions in the lungs and ulceration ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Burkholderia Mallei
''Burkholderia mallei'' is a Gram-negative, bipolar, aerobic bacterium, a human and animal pathogen of genus ''Burkholderia'' causing glanders; the Latin name of this disease (''malleus'') gave its name to the species causing it. It is closely related to '' B. pseudomallei,'' and by multilocus sequence typing it is a subspecies of ''B. pseudomallei.'' ''B. mallei'' evolved from ''B. pseudomallei'' by selective reduction and deletions from the ''B. pseudomallei'' genome. Unlike ''B. pseudomallei'' and other genus members, ''B. mallei'' is nonmotile; its shape is coccobacillary measuring some 1.5–3.0 μm in length and 0.5–1.0 μm in diameter with rounded ends. Discovery and early history Wilhelm Schütz and Friedrich Löffler first isolated ''B. mallei'' in 1882. It was isolated from an infected liver and spleen of a horse. This bacterium is also one of the first to be identified containing a type VI secretion system which is important for it ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mallein Test
The mallein test is a sensitive and specific clinical test for glanders, a common bacterial disease of equids (horses, donkeys, mules). This test is an allergic hypersensitivity test used as a diagnosis for glanders. It is caused by a bacterium called ''Burkholderia mallei'', which is contagious for humans and other species. The occurrence of glanders must be reported to the World Organisation for Animal Health. Mallein, a protein fraction of ''B. mallei'', is usually injected by an eye-drop. If an animal is infected, the animal will show swelling in the eye from around 48 hours of injection and may be accompanied by secretion and conjunctivitis. Mallein is non toxic to normal animals. History Mallein was discovered in 1890. Before 1934, glanders was widespread. In the early 1900s, glanders was common in Europe, the United States of America, and Canada, and has been successfully eliminated by mass testing and the slaughter and destruction of campaigns. Glanders is still present ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Melioidosis
Melioidosis is an infectious disease caused by a gram-negative bacterium called ''Burkholderia pseudomallei''. Most people exposed to ''B. pseudomallei'' experience no symptoms; however, those who do experience symptoms have signs and symptoms that range from mild such as fever and skin changes, to severe with pneumonia, abscesses, and septic shock that could cause death. Approximately 10% of people with melioidosis develop symptoms that last longer than two months, termed "chronic melioidosis". Humans are infected with ''B. pseudomallei'' by contact with contaminated soil or water. The bacteria enter the body through wounds, inhalation, or ingestion. Person-to-person or animal-to-human transmission is extremely rare. The infection is constantly present in Southeast Asia particularly in northeast Thailand and northern Australia. In temperate countries such as Europe and the United States, melioidosis cases are usually imported from countries where melioidosis is endemic. The sign ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bioterrorism
Bioterrorism is terrorism involving the intentional release or dissemination of biological agents. These agents are bacteria, viruses, insects, fungi, and/or toxins, and may be in a naturally occurring or a human-modified form, in much the same way as in biological warfare. Further, modern agribusiness is vulnerable to anti-agricultural attacks by terrorists, and such attacks can seriously damage economy as well as consumer confidence. The latter destructive activity is called agrobioterrorism and is a subtype of agro-terrorism. Definition Bioterrorism is the deliberate release of viruses, bacteria, toxins or other harmful agents to cause illness or death in people, animals, or plants. These agents are typically found in nature, but could be mutated or altered to increase their ability to cause disease, make them resistant to current medicines, or to increase their ability to be spread into the environment. Biological agents can be spread through the air, water, or in food. Bi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bioterrorism
Bioterrorism is terrorism involving the intentional release or dissemination of biological agents. These agents are bacteria, viruses, insects, fungi, and/or toxins, and may be in a naturally occurring or a human-modified form, in much the same way as in biological warfare. Further, modern agribusiness is vulnerable to anti-agricultural attacks by terrorists, and such attacks can seriously damage economy as well as consumer confidence. The latter destructive activity is called agrobioterrorism and is a subtype of agro-terrorism. Definition Bioterrorism is the deliberate release of viruses, bacteria, toxins or other harmful agents to cause illness or death in people, animals, or plants. These agents are typically found in nature, but could be mutated or altered to increase their ability to cause disease, make them resistant to current medicines, or to increase their ability to be spread into the environment. Biological agents can be spread through the air, water, or in food. Bi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biological Warfare
Biological warfare, also known as germ warfare, is the use of biological toxins or infectious agents such as bacteria, viruses, insects, and fungi with the intent to kill, harm or incapacitate humans, animals or plants as an act of war. Biological weapons (often termed "bio-weapons", "biological threat agents", or "bio-agents") are living organisms or replicating entities ( ''i.e.'' viruses, which are not universally considered "alive"). Entomological (insect) warfare is a subtype of biological warfare. Offensive biological warfare is prohibited under customary international humanitarian law and several international treaties. In particular, the 1972 Biological Weapons Convention (BWC) bans the development, production, acquisition, transfer, stockpiling and use of biological weapons. Therefore, the use of biological agents in armed conflict is a war crime. In contrast, defensive biological research for prophylactic, protective or other peaceful purposes is not proh ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Battle Of Blenheim
The Battle of Blenheim (german: Zweite Schlacht bei Höchstädt, link=no; french: Bataille de Höchstädt, link=no; nl, Slag bij Blenheim, link=no) fought on , was a major battle of the War of the Spanish Succession. The overwhelming Allied victory ensured the safety of Vienna from the Franco-Bavarian army, thus preventing the collapse of the reconstituted Grand Alliance. Louis XIV of France sought to knock the Holy Roman Emperor, Leopold, out of the war by seizing Vienna, the Habsburg capital, and gain a favourable peace settlement. The dangers to Vienna were considerable: Maximilian II Emanuel, Elector of Bavaria, and Marshal Ferdinand de Marsin's forces in Bavaria threatened from the west, and Marshal Louis Joseph de Bourbon, duc de Vendôme's large army in northern Italy posed a serious danger with a potential offensive through the Brenner Pass. Vienna was also under pressure from Rákóczi's Hungarian revolt from its eastern approaches. Realising the danger, the Duke ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Zoonosis
A zoonosis (; plural zoonoses) or zoonotic disease is an infectious disease of humans caused by a pathogen (an infectious agent, such as a bacterium, virus, parasite or prion) that has jumped from a non-human (usually a vertebrate) to a human. Typically, the first infected human transmits the infectious agent to at least one other human, who, in turn, infects others. Major modern diseases such as Ebola virus disease and salmonellosis are zoonoses. HIV was a zoonotic disease transmitted to humans in the early part of the 20th century, though it has now evolved into a separate human-only disease. Most strains of influenza that infect humans are human diseases, although many strains of bird flu and swine flu are zoonoses; these viruses occasionally recombine with human strains of the flu and can cause pandemics such as the 1918 Spanish flu or the 2009 swine flu. ''Taenia solium'' infection is one of the neglected tropical diseases with public health and veterinary concern in en ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Subcutaneous Tissue
The subcutaneous tissue (), also called the hypodermis, hypoderm (), subcutis, superficial fascia, is the lowermost layer of the integumentary system in vertebrates. The types of cells found in the layer are fibroblasts, adipose cells, and macrophages. The subcutaneous tissue is derived from the mesoderm, but unlike the dermis, it is not derived from the mesoderm's dermatome region. It consists primarily of loose connective tissue, and contains larger blood vessels and nerves than those found in the dermis. It is a major site of fat storage in the body. In arthropods, a hypodermis can refer to an epidermal layer of cells that secretes the chitinous cuticle. The term also refers to a layer of cells lying immediately below the epidermis of plants. Structure * Fibrous bands anchoring the skin to the deep fascia * Collagen and elastin fibers attaching it to the dermis * Fat is absent from the eyelids, clitoris, penis, much of pinna, and scrotum * Blood vessels on route to the der ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eastern Front (World War I)
The Eastern Front or Eastern Theater of World War I (german: Ostfront; ro, Frontul de răsărit; russian: Восточный фронт, Vostochny front) was a theater (warfare), theater of operations that encompassed at its greatest extent the entire frontier between Russian Empire, Russia and Kingdom of Romania, Romania on one side and Austria-Hungary, Kingdom of Bulgaria, Bulgaria, the Ottoman Empire, Ottoman Empire, and German Empire, Germany on the other. It stretched from the Baltic Sea in the north to the Black Sea in the south, involved most of Eastern Europe, and stretched deep into Central Europe as well. The term contrasts with "Western Front (World War I), Western Front", which was being fought in Belgium and French Third Republic, France. During 1910, Russian General Yuri Danilov developed "Plan 19" under which four armies would invade East Prussia. This plan was criticised as Austria-Hungary could be a greater threat than the German Empire. So instead of four arm ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Russian Empire
The Russian Empire was an empire and the final period of the Russian monarchy from 1721 to 1917, ruling across large parts of Eurasia. It succeeded the Tsardom of Russia following the Treaty of Nystad, which ended the Great Northern War. The rise of the Russian Empire coincided with the decline of neighbouring rival powers: the Swedish Empire, the Polish–Lithuanian Commonwealth, Qajar Iran, the Ottoman Empire, and Qing China. It also held colonies in North America between 1799 and 1867. Covering an area of approximately , it remains the third-largest empire in history, surpassed only by the British Empire and the Mongol Empire; it ruled over a population of 125.6 million people per the 1897 Russian census, which was the only census carried out during the entire imperial period. Owing to its geographic extent across three continents at its peak, it featured great ethnic, linguistic, religious, and economic diversity. From the 10th–17th centuries, the land ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
German Empire
The German Empire (),Herbert Tuttle wrote in September 1881 that the term "Reich" does not literally connote an empire as has been commonly assumed by English-speaking people. The term literally denotes an empire – particularly a hereditary empire led by an emperor, although has been used in German to denote the Roman Empire because it had a weak hereditary tradition. In the case of the German Empire, the official name was , which is properly translated as "German Empire" because the official position of head of state in the constitution of the German Empire was officially a "presidency" of a confederation of German states led by the King of Prussia who would assume "the title of German Emperor" as referring to the German people, but was not emperor of Germany as in an emperor of a state. –The German Empire" ''Harper's New Monthly Magazine''. vol. 63, issue 376, pp. 591–603; here p. 593. also referred to as Imperial Germany, the Second Reich, as well as simply Germany, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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