Chorion
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Chorion
The chorion is the outermost fetal membrane around the embryo in mammals, birds and reptiles (amniotes). It develops from an outer fold on the surface of the yolk sac, which lies outside the zona pellucida (in mammals), known as the vitelline membrane in other animals. In insects it is developed by the follicle cells while the egg is in the ovary.Chapman, R.F. (1998) "The insects: structure and function", Section ''The egg and embryology''. Previewed in Google Bookon 26 Sep 2009. Structure In humans and other mammals (excluding monotremes), the chorion is one of the fetal membranes that exist during pregnancy between the developing fetus and mother. The chorion and the amnion together form the amniotic sac. In humans it is formed by extraembryonic mesoderm and the two layers of trophoblast that surround the embryo and other membranes; the chorionic villi emerge from the chorion, invade the endometrium, and allow the transfer of nutrients from maternal blood to fetal blood. ...
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Fetal Membrane
The fetal membranes are the four extraembryonic membranes, associated with the developing embryo, and fetus in humans and other mammals.. They are the amnion, chorion, allantois, and yolk sac. The amnion and the chorion are the chorioamniotic membranes that make up the amniotic sac which surrounds and protects the embryo. The fetal membranes are four of six accessory organs developed by the conceptus that are not part of the embryo itself, the other two are the placenta, and the umbilical cord. Structure The fetal membranes surround the developing embryo and form the fetal-maternal interface. The fetal membranes are derived from the trophoblast layer (outer layer of cells) of the implanting blastocyst. The trophoblast layer differentiates into amnion and the chorion, which then comprise the fetal membranes. The amnion is the innermost layer and, therefore, contacts the amniotic fluid, the fetus and the umbilical cord. The internal pressure of the amniotic fluid causes th ...
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Chorionic Villi
Chorionic villi are villi that sprout from the chorion to provide maximal contact area with maternal blood. They are an essential element in pregnancy from a histomorphologic perspective, and are, by definition, a product of conception. Branches of the umbilical arteries carry embryonic blood to the villi. After circulating through the capillaries of the villi, blood returns to the embryo through the umbilical vein. Thus, villi are part of the border between maternal and fetal blood during pregnancy. Structure Villi can also be classified by their relations: * Floating villi float freely in the intervillous space. They exhibit a bi-layered epithelium consisting of cytotrophoblasts with overlaying syncytium ( syncytiotrophoblast). * Anchoring (stem) villi stabilize mechanical integrity of the placental-maternal interface. Development The chorion undergoes rapid proliferation and forms numerous processes, the chorionic villi, which invade and destroy the uterine decidua and a ...
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Amnion
The amnion is a membrane that closely covers the human and various other embryos when first formed. It fills with amniotic fluid, which causes the amnion to expand and become the amniotic sac that provides a protective environment for the developing embryo. The amnion, along with the chorion, the yolk sac and the allantois protect the embryo. In birds, reptiles and monotremes, the protective sac is enclosed in a shell. In marsupials and placental mammals, it is enclosed in a uterus. The term is from Ancient Greek ἀμνίον 'little lamb', diminutive of ἀμνός 'lamb'. it is cognate with the English verb 'yean', bring forth young (usually lambs). The amnion is a feature of the vertebrate clade ''Amniota'', which includes reptiles, birds, and mammals. Amphibians and fish are not amniotes and thus lack the amnion. The amnion stems from the extra-embryonic somatic mesoderm on the outer side and the extra-embryonic ectoderm or trophoblast on the inner side. In humans In the ...
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Cytotrophoblast
"Cytotrophoblast" is the name given to both the inner layer of the trophoblast (also called layer of Langhans) or the cells that live there. It is interior to the syncytiotrophoblast and external to the wall of the blastocyst in a developing embryo. The cytotrophoblast is considered to be the trophoblastic stem cell because the layer surrounding the blastocyst remains while daughter cells differentiate and proliferate to function in multiple roles. There are two lineages that cytotrophoblastic cells may differentiate through: fusion and invasive. The fusion lineage yields syncytiotrophoblast and the invasive lineage yields interstitial cytotrophoblast cells. Cytotrophoblastic cells play an important role in the implantation of an embryo in the uterus. Fusion lineage The formation of all syncytiotrophoblast is from the fusion of two or more cytotrophoblasts via this fusion pathway. This pathway is important because the syncytiotrophoblast plays an important role in fetal-maternal ...
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Cotyledon Arteries
The placenta of humans, and certain other mammals contains structures known as cotyledons, which transmit fetal blood and allow exchange of oxygen and nutrients with the maternal blood. Ruminants The Artiodactyla have a cotyledonary placenta. In this form of placenta the chorionic villi form a number of separate circular structures (''cotyledons'') which are distributed over the surface of the chorionic sac. Sheep, goats and cattle have between 72 and 125 cotyledons whereas deer have 4-6 larger cotyledons. Human The form of the human placenta is generally classified as a discoid placenta. Within this the ''cotyledons'' are the approximately 15-25 separations of the decidua basalis of the placenta, separated by placental septa.Page 565 in:/ref> Each cotyledon consists of a main stem of a chorionic villus as well as its branches and sub-branches. Vasculature The cotyledons receive fetal blood from chorionic vessels Chorionic (plate) vessels, also fetal surface vessels are blood ...
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Syncytiotrophoblast
Syncytiotrophoblast (from the Greek 'syn'- "together"; 'cytio'- "of cells"; 'tropho'- "nutrition"; 'blast'- "bud") is the epithelial covering of the highly vascular embryonic placental villi, which invades the wall of the uterus to establish nutrient circulation between the embryo and the mother. It is a multi-nucleate, terminally differentiated syncytium, extending to 13cm. Function It is the outer layer of the trophoblasts and actively invades the uterine wall, during implantation, rupturing maternal capillaries and thus establishing an interface between maternal blood and embryonic extracellular fluid, facilitating passive exchange of material between the mother and the embryo. The syncytial property is important since the mother's immune system includes white blood cells that are able to migrate into tissues by "squeezing" in between cells. If they were to reach the fetal side of the placenta many foreign proteins would be recognised, triggering an immune reaction. Howeve ...
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Pregnancy
Pregnancy is the time during which one or more offspring develops ( gestates) inside a woman's uterus (womb). A multiple pregnancy involves more than one offspring, such as with twins. Pregnancy usually occurs by sexual intercourse, but can also occur through assisted reproductive technology procedures. A pregnancy may end in a live birth, a miscarriage, an induced abortion, or a stillbirth. Childbirth typically occurs around 40 weeks from the start of the last menstrual period (LMP), a span known as the gestational age. This is just over nine months. Counting by fertilization age, the length is about 38 weeks. Pregnancy is "the presence of an implanted human embryo or fetus in the uterus"; implantation occurs on average 8–9 days after fertilization. An '' embryo'' is the term for the developing offspring during the first seven weeks following implantation (i.e. ten weeks' gestational age), after which the term ''fetus'' is used until birth. Signs an ...
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Chorionic Arteries
Chorionic (plate) vessels, also fetal surface vessels are blood vessels, including both arteries and veins, that carry blood through the chorion in the fetoplacental circulation. Chorionic arteries branch off the umbilical artery, and supply the capillaries of the chorionic villi. Increased vasocontractility of chorionic arteries may contribute to preeclampsia Pre-eclampsia is a disorder of pregnancy characterized by the onset of high blood pressure and often a significant amount of protein in the urine. When it arises, the condition begins after 20 weeks of pregnancy. In severe cases of the disease .... References Embryology of cardiovascular system {{circulatory-stub ...
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Trophoblast
The trophoblast (from Greek : to feed; and : germinator) is the outer layer of cells of the blastocyst. Trophoblasts are present four days after fertilization in humans. They provide nutrients to the embryo and develop into a large part of the placenta. They form during the first stage of pregnancy and are the first cells to differentiate from the fertilized egg to become extraembryonic structures that do not directly contribute to the embryo. After gastrulation, the trophoblast is contiguous with the ectoderm of the embryo and is referred to as the trophectoderm. After the first differentiation, the cells in the human embryo lose their totipotency and are no longer totipotent stem cells because they cannot form a trophoblast. They are now pluripotent stem cells. Structure The trophoblast proliferates and differentiates into two cell layers at approximately six days after fertilization for humans. Function Trophoblasts are specialized cells of the placenta that play an i ...
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Reptiles
Reptiles, as most commonly defined are the animals in the Class (biology), class Reptilia ( ), a paraphyletic grouping comprising all sauropsid, sauropsids except birds. Living reptiles comprise turtles, crocodilians, Squamata, squamates (lizards and snakes) and rhynchocephalians (tuatara). As of March 2022, the Reptile Database includes about 11,700 species. In the traditional Linnaean taxonomy, Linnaean classification system, birds are considered a separate class to reptiles. However, crocodilians are more closely related to birds than they are to other living reptiles, and so modern Cladistics, cladistic classification systems include birds within Reptilia, redefining the term as a clade. Other cladistic definitions abandon the term reptile altogether in favor of the clade Sauropsida, which refers to all amniotes more closely related to modern reptiles than to mammals. The study of the traditional reptile Order (biology), orders, historically combined with that of modern amphi ...
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Amniotic Sac
The amniotic sac, also called the bag of waters or the membranes, is the sac in which the embryo and later fetus develops in amniotes. It is a thin but tough transparent pair of membranes that hold a developing embryo (and later fetus) until shortly before birth. The inner of these membranes, the amnion, encloses the amniotic cavity, containing the amniotic fluid and the embryo. The outer membrane, the chorion, contains the amnion and is part of the placenta. On the outer side, the amniotic sac is connected to the yolk sac, the allantois, and via the umbilical cord, the placenta. The yolk sac, amnion, chorion, and allantois are the four extraembryonic membranes that lie outside of the embryo and are involved in providing nutrients and protection to the developing embryo. They form from the inner cell mass; the first to form is the yolk sac followed by the amnion which grows over the developing embryo. The amnion remains an important extraembryonic membrane throughout prenatal dev ...
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Amniotes
Amniotes are a clade of tetrapod vertebrates that comprises sauropsids (including all reptiles and birds, and extinct parareptiles and non-avian dinosaurs) and synapsids (including pelycosaurs and therapsids such as mammals). They are distinguished from the other tetrapod clade — the amphibians — by the development of three extraembryonic membranes ( amnion for embryoic protection, chorion for gas exchange, and allantois for metabolic waste disposal or storage), thicker and more keratinized skin, and costal respiration (breathing by expanding/constricting the rib cage). All three main features listed above, namely the presence of an amniotic buffer, water-impermeable cutes and a robust respiratory system, are very important for amniotes to live on land as true terrestrial animals – the ability to reproduce in locations away from water bodies, better homeostasis in drier environments, and more efficient air respiration to power terrestrial locomotions, although they migh ...
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