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Cliotide
Cliotides are a group of related peptides that have been isolated from the heat-stable fraction of ''Clitoria ternatea'' (Cliotides) extracts. Cliotides belong to a larger classification of peptides, the cyclotides. Preliminary studies show that cliotides display a variety of biochemical properties which have attracted scientific interest in the possibility of developing antimicrobial and anti-cancer agents from them. Cliotides display ''in vitro'' antimicrobial activity against ''Escherichia coli, E. coli'', ''Klebsiella pneumoniae, K. pneumoniae'', and ''Pseudomonas aeruginosa, P. aeruginosa'' and cytotoxicity against HeLa cells. Cliotides also possess immunostimulating activity. At a concentration of 1 μM, cationic cliotides are capable of augmenting the secretion of various cytokines and chemokines in human monocytes at both resting and LPS-stimulated states. Chemokines such as RANTES, MIP-1β, MIP-1α, IP-10, IL-8 and TNF-α were among the most upregulated with up to 129-fold ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clitoria Ternatea
''Clitoria ternatea'', commonly known as Asian pigeonwings, bluebellvine, blue pea, butterfly pea, cordofan pea or Darwin pea is a plant species belonging to the family Fabaceae, endemic and native to the Indonesian island of Ternate. In India, it is revered as a holy flower, used in daily puja rituals. Etymology The genus name of ''Clitoria'' is a direct translation from the local name of these plant in the Ternate language; which called as , literally means "clitoris" due to its shape that resembles the shape of human female genitals. The first reference to the genus, which includes an illustration of the plant, was made in 1678 by Jakób Breyne, a Polish naturalist, who described it as ''Flos clitoridis ternatensibus'', meaning ' Ternatean flower of the clitoris'. Meanwhile on the other hand, the species name is derived from the name of the island where these Linnaeus's specimens originated; which is the Ternate Island located in northern part of the Maluku Islands. Dis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |