Actin-binding Domain

	Actin-binding Domain Actin-binding proteins (also known as ABPs) are binding protein, proteins that bind to actin. This may mean ability to bind actin monomers, or polymers, or both. Many actin-binding proteins, including α-actinin, β-spectrin, dystrophin, utrophin and fimbrin, do this through the actin-binding calponin homology domain. This is a list of actin-binding proteins in alphabetical order. 0–9 25kDa 25kDa ABP from aorta p185neu 30akDA 110 kD dimer ABP 30bkDa 110 kD (Drebrin) 34kDA 45kDa p53 p58gag p116rip A a-actinin Abl gene, Abl AbLIM Actin-Interacting MAPKKK ABP120 ABP140 Abp1p ABP280 (Filamin) ABP50 (EF-1a) Acan 125 (Carmil) Actin assembly-inducing protein, ActA Actibind Actin Actinfilin Actinogelin Actin-regulating kinases Actin-Related Proteins Actobindin Actolinkin Actopaxin Actophorin Acumentin (= L-plastin) Adducin Cofilin, ADF/Cofilin Adseverin (scinderin) Afadin AFAP-110 Affixin Aginactin AIP1 Aldolase Angiogenin Anillin Annexin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Binding Protein A binding protein is any protein that acts as an agent to bind two or more molecules together. Examples include: DNA-binding protein Single-strand binding protein Telomere-binding protein RNA-binding protein Poly(A)-binding protein Nuclear cap-binding protein complex * CREB-binding protein Calcium-binding protein Calcium-binding protein 1 * S100 calcium-binding protein A1 TATA-binding protein Actin-binding protein Most actin binding proteins bind on the actin surface, despite having different functions and structures. Penicillin binding proteins Retinol binding protein *Retinol binding protein 4 EP300 Binding immunoglobulin protein Odorant binding protein Lipopolysaccharide-binding protein C4b-binding protein Rap GTP-binding protein Calmodulin-binding proteins Iron-binding proteins Thyroxine-binding proteins Folate-binding protein Sterol regulatory element-binding protein GTP-binding protein Retinaldehyde-binding protein 1 Ccaat-enhancer-bind ... [...More Info...] [...Related Items...] OR:* [Wikipedia] [Google] [Baidu]
picture info	Actin Actin is a family of globular multi-functional proteins that form microfilaments in the cytoskeleton, and the thin filaments in muscle fibrils. It is found in essentially all eukaryotic cells, where it may be present at a concentration of over 100 μM; its mass is roughly 42 kDa, with a diameter of 4 to 7 nm. An actin protein is the monomeric subunit of two types of filaments in cells: microfilaments, one of the three major components of the cytoskeleton, and thin filaments, part of the contractile apparatus in muscle cells. It can be present as either a free monomer called G-actin (globular) or as part of a linear polymer microfilament called F-actin (filamentous), both of which are essential for such important cellular functions as the mobility and contraction of cells during cell division. Actin participates in many important cellular processes, including muscle contraction, cell motility, cell division and cytokinesis, vesicle and organelle movement, cell sign ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Actibind Actibind is an actin-binding fungal T(2)-RNase protein that is produced by the black mold ''Aspergillus niger'', a microorganism used in biotechnology and food technology. In plants, actibind binds actin, a major component of the cytoskeleton, interfering with the plants' pollen tubes and halting cell growth. Research published in the journal ''Cancer'' on 15 May 2006 reports evidence that actibind has antiangiogenic and anticarcinogenic characteristics. In human colon cancer, breast cancer and melanoma, increasing the level of actibind was found to reduce the ability of these cells to form tumorogenic colonies. In animal models, increased actibind inhibited the growth of colon cancer-derived tumors, metastases and blood vessel formation. During the completion of the Human Genome Project, the gene encoding for RNaseT2, the human actibind-like protein, was found on chromosome 6 Chromosome 6 is one of the 23 pairs of chromosomes in humans. People normally have two copies of thi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Actin Assembly-inducing Protein The Actin assembly-inducing protein (ActA) is a protein encoded and used by ''Listeria monocytogenes'' to propel itself through a mammalian host cell. ActA is a bacterial surface protein comprising a membrane-spanning region. In a mammalian cell the bacterial ActA interacts with the Arp2/3 complex and actin monomers to induce actin polymerization on the bacterial surface generating an actin comet tail. The gene encoding ActA is named ''actA'' or prtB. Introduction As soon as ''L. monocytogenes'' bacteria are ingested by humans, they get internalized into intestinal epithelium cells and rapidly try to escape their internalization vacuole. In the cytosol they start to polymerize actin on their surface by the help of the ActA protein. It has been shown that ActA is not only necessary but also sufficient to induce motility of bacteria in the absence of other bacterial factors. Discovery ActA was discovered by analysing lecithinase-negative Tn''917-lac'' Listeria mutants because of t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]