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Curare
Curare ( or ; or ) is a common name for various alkaloid arrow poisons originating from plant extracts. Used as a paralyzing agent by indigenous peoples in Central and South America for hunting and for therapeutic purposes, curare only becomes active when it contaminates a wound or is introduced directly to the bloodstream; it is not active when ingested orally. These poisons cause weakness of the skeletal muscles and, when administered in a sufficient dose, eventual death by asphyxiation due to paralysis of the diaphragm. Curare is prepared by boiling the bark of one of the dozens of plant sources, leaving a dark, heavy paste that can be applied to arrow or dart heads. In medicine, curare has been used as a treatment for tetanus and strychnine poisoning and as a paralyzing agent for surgical procedures. History The word 'curare' is derived from ''wurari'', from the Carib language of the Macusi of Guyana. It has its origins in the Carib phrase "mawa cure" meaning of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tubocurarine Chloride
Tubocurarine (also known as ''d''-tubocurarine or DTC) is a toxic alkaloid historically known for its use as an arrow poison. In the mid-1900s, it was used in conjunction with an anesthetic to provide skeletal muscle relaxation during surgery or mechanical ventilation. It is now rarely used as an adjunct for clinical anesthesia because safer alternatives, such as cisatracurium and rocuronium, are available. History Tubocurarine is a naturally occurring mono-quaternary alkaloid obtained from the bark of the Menispermaceous South American plant ''Chondrodendron tomentosum'', a climbing vine known to the European world since the Spanish conquest of South America. Curare had been used as a source of arrow poison by South American natives to hunt animals, and they were able to eat the animals' contaminated flesh subsequently without any adverse effects because tubocurarine cannot easily cross mucous membranes. Thus, tubocurarine is effective only if given parenterally, as demonstrate ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chondrodendron Tomentosum
''Chondrodendron tomentosum'' is one of six accepted species in the small genus Chondrodendron, belonging to the Moonseed family Menispermaceae. It is a large tropical liana native to Central America, Central and South America.It contains highly toxic alkaloids and is one of the sources of the arrow poison curare - specifically 'tube curare', the name of which is derived from the name of the medicinally valuable alkaloid tubocurarine. Derivation of scientific name The generic name is a compound of Greek χόνδρος ( chondros ) 'cartilage' / 'lump' / 'grain' and δένδρον ( dendron ) 'tree' - hence 'lumpy / gristly tree', while the specific name consists of the Latin adjectival form ''tomentosum'' 'covered in matted hairs'. The binomial in its entirety thus conveys the image of a rather large coarse plant. Description Chondrodendron tomentosum is a woody climbing plant with stems that can reach 10 cm in thickness at the base and which can climb up to 30 metres into ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Yagua People
Yagua are an indigenous people in Colombia and northeastern Peru, numbering approximately 6,000. Currently, they live near the Amazon, Napo, Putumayo and Yavari rivers and their tributaries. As of 2005, some Yagua have migrated northward to Colombia, near the town of Leticia. Location Currently the Yagua live in some 30 communities scattered throughout a section of the Peruvian and Colombian Amazon basin which can roughly be described as a rectangle 200 miles wide and 350 miles long (70,000 sq. miles) extending southward from the second to the fifth parallel and westward from the 70th to the 75th meridian west. Language The Yagua language is classified as a Peba-Yaguan language. The only closely related languages that have been documented are Peba and YameoEspinosa 1955 both of which are now extinct. 2000 Yagua people in Peru were monolingual in 2000, and of these, 75% were women and 25% were men. The majority of the rest are bilingual in Spanish to varying degrees. Na ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Caribbean
The Caribbean (, ) ( es, El Caribe; french: la Caraïbe; ht, Karayib; nl, De Caraïben) is a region of the Americas that consists of the Caribbean Sea, its islands (some surrounded by the Caribbean Sea and some bordering both the Caribbean Sea and the North Atlantic Ocean) and the surrounding coasts. The region is southeast of the Gulf of Mexico and the North American mainland, east of Central America, and north of South America. Situated largely on the Caribbean Plate, the region has more than 700 islands, islets, reefs and cays (see the list of Caribbean islands). Island arcs delineate the eastern and northern edges of the Caribbean Sea: The Greater Antilles and the Lucayan Archipelago on the north and the Lesser Antilles and the on the south and east (which includes the Leeward Antilles). They form the West Indies with the nearby Lucayan Archipelago (the Bahamas and Turks and Caicos Islands), which are considered to be part of the Caribbean despite not bordering the Caribbe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lesser Antilles
The Lesser Antilles ( es, link=no, Antillas Menores; french: link=no, Petites Antilles; pap, Antias Menor; nl, Kleine Antillen) are a group of islands in the Caribbean Sea. Most of them are part of a long, partially volcanic island arc between the Greater Antilles to the north-west and the continent of South America."West Indies." ''Merriam-Webster's Geographical Dictionary'', 3rd ed. 2001. () Springfield, MA: Merriam-Webster Inc., p. 1298. The islands of the Lesser Antilles form the eastern boundary of the Caribbean Sea where it meets the Atlantic Ocean. Together, the Lesser Antilles and the Greater Antilles make up the Antilles. (Somewhat confusingly, the word Caribbean is sometimes used to refer only to the Antilles, and sometimes used to refer to a much larger region.) The Lesser and Greater Antilles, together with the Lucayan Archipelago, are collectively known as the West Indies. History after European arrival The Spanish were the first Europeans to arrive on the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kalinago
The Kalinago, also known as the Island Caribs or simply Caribs, are an indigenous people of the Lesser Antilles in the Caribbean. They may have been related to the Mainland Caribs (Kalina) of South America, but they spoke an unrelated language known as Island Carib. They also spoke a pidgin language associated with the Mainland Caribs. At the time of Spanish contact, the Kalinago were one of the dominant groups in the Caribbean, which owes its name to them. They lived throughout northeastern South America, Trinidad and Tobago, Barbados, the Windward Islands, Dominica, and possibly the southern Leeward Islands. Historically, it was thought their ancestors were mainland peoples who had conquered the islands from their previous inhabitants, the Igneri. However, linguistic and archaeological evidence contradicts the notion of a mass emigration and conquest; the Kalinago language appears not to have been Cariban, but like that of their neighbors, the Taíno. Irving Rouse and other ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blowgun
A blowgun (also called a blowpipe or blow tube) is a simple ranged weapon consisting of a long narrow tube for shooting light projectiles such as darts. It operates by having the projectile placed inside the pipe and using the force created by forced exhalation ("blow") to pneumatically propel the projectile. The propulsive power is limited by the strength of the user's respiratory muscles and the vital capacity of their lungs. History Many cultures have used such a weapon, but various indigenous peoples of Eastern Asia, Southeast Asia, Western Europe, North America, Central America (the Huehuetenango region of Guatemala), and South America (the Amazon Basin and the Guianas) are best known for its historical usage. Projectiles include seeds, clay pellets, and darts. Some cultures dip the tip of the darts in curare or other arrow poisons in order to paralyze the target. Blowguns were very rarely used by these tribes as anti-personnel weapons, but primarily to hunt small ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of California, Los Angeles
The University of California, Los Angeles (UCLA) is a public land-grant research university in Los Angeles, California. UCLA's academic roots were established in 1881 as a teachers college then known as the southern branch of the California State Normal School (now San José State University). This school was absorbed with the official founding of UCLA as the Southern Branch of the University of California in 1919, making it the second-oldest of the 10-campus University of California system (after UC Berkeley). UCLA offers 337 undergraduate and graduate degree programs in a wide range of disciplines, enrolling about 31,600 undergraduate and 14,300 graduate and professional students. UCLA received 174,914 undergraduate applications for Fall 2022, including transfers, making the school the most applied-to university in the United States. The university is organized into the College of Letters and Science and 12 professional schools. Six of the schools offer undergraduate degre ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Toxiferine
Toxiferine (C-toxiferine I) is a curare toxin. It is a bisindole alkaloid derived from ''Strychnos toxifera'' and a nicotinic acetylcholine receptor antagonist. This alkaloid is the main toxic component of Calabash curare, and one of the most toxic plant alkaloids known. The lethal dose (LD50) for mice has been determined as 10 - 60 µg/kg by intravenous administration. It is a muscle relaxant that causes paralysis of skeletal muscle, which takes approximately 2 hours to recovery for a moderate dose, and 8 hours of total paralysis with a 20-fold paralytic dose. The paralysis can be antagonized by neostigmine Neostigmine, sold under the brand name Bloxiverz, among others, is a medication used to treat myasthenia gravis, Ogilvie syndrome, and urinary retention without the presence of a blockage. It is also used in anaesthesia to end the effects of n ... References Indole alkaloids Nicotinic antagonists Quaternary ammonium compounds Neuromuscular blockers Neurotox ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Calabash
Calabash (; ''Lagenaria siceraria''), also known as bottle gourd, white-flowered gourd, long melon, birdhouse gourd, New Guinea bean, Tasmania bean, and opo squash, is a vine grown for its fruit. It can be either harvested young to be consumed as a vegetable, or harvested mature to be dried and used as a utensil, container, or a musical instrument. When it is fresh, the fruit has a light green smooth skin and white flesh. Calabash fruits have a variety of shapes: they can be huge and rounded, small and bottle-shaped, or slim and serpentine, and they can grow to be over a metre long. Rounder varieties are typically called calabash gourds. The gourd was one of the world's first cultivated plants grown not primarily for food, but for use as containers. The bottle gourd may have been carried from Asia to Africa, Europe, and the Americas in the course of human migration, or by seeds floating across the oceans inside the gourd. It has been proven to have been globally domesticated (an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Crescentia Cujete
''Crescentia cujete'', commonly known as the calabash tree, is a species of flowering plant native to the Americas, that is grown in Africa, Central America, South America, the West Indies and extreme southern Florida. It is the national tree of St. Lucia. It is a dicotyledonous plant with simple leaves, which are alternate or in fascicles (clusters) on short shoots. It is naturalized in India. The tree shares its common name with that of the vine calabash, or bottle gourd (''Lagenaria siceraria''). In Cuba, this tree is known to grow in both disturbed habitat and areas of poor drainage. It can grow up to 10 meters tall. Uses Caribbean A calabash is primarily used to make utensils such as cups, bowls, and basins in rural areas. It can be used for carrying water, or for transporting fish, when fishing. In some Caribbean countries, it is worked, painted, and decorated and turned into items by artisans, and sold to tourists. As a cup, bowl, or even a water-pipe or "bong", the c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Terra Cotta
Terracotta, terra cotta, or terra-cotta (; ; ), in its material sense as an earthenware substrate, is a clay-based unglazed or glazed ceramic where the fired body is porous. In applied art, craft, construction, and architecture, terracotta is the term normally used for sculpture made in earthenware and also for various practical uses, including vessels (notably flower pots), water and waste water pipes, roofing tiles, bricks, and surface embellishment in building construction. The term is also used to refer to the natural brownish orange color of most terracotta. In archaeology and art history, "terracotta" is often used to describe objects such as figurines not made on a potter's wheel. Vessels and other objects that are or might be made on a wheel from the same material are called earthenware pottery; the choice of term depends on the type of object rather than the material or firing technique. Unglazed pieces, and those made for building construction and industry, are ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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