YIPF6
The Yip1 domain family is a group of proteins involved in regulating Secretion, secretory traffic in eukaryotes. The family consists of four members in yeast and nine members in humans. Family members have a shared architecture containing five transmembrane domains. Evolution Yip1 domain family members are found in all eukaryotes. The budding yeast ''Saccharomyces cerevisiae'' has four Yip1 domain family members: Yif1p, Yip1p, Yip4p, and Yip5p. The amino acid sequence of the Yip domain family members divides them into two groups, called α-subunits and β-subunits. The α-subunits – in yeast Yip1p and Yip4p – are more closely related to each other than they are to the β-subunits, Yip5p and Yif1p. In mammals, both groups are expanded, with α-subunits YipF4, YipF5, YipF6, and YipF7; as well as β-subunits Yif1A, Yif1B, YipF1, YipF2, and YipF3. Function Yip1 domain family members localize to the Golgi apparatus, where they interact with each other to form complexes involved in ...
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