Walter J. Koch
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Walter J. Koch
Walter J. “Wally” Koch (born March 2, 1961) is an American scientist best known for his work with G protein-coupled receptors in the heart and gene therapy approaches to cardiovascular disease. He is currently an Instructor at Duke University, and formerly at Lewis Katz School of Medicine at Temple University where he was the Director of the Center for Translational Medicine, Professor and Chairman of the Department of Pharmacology, and W.W. Smith Chair in Cardiovascular Medicine. In 2013, he co-founded the biotech company, Renovacor. Early life Koch was born on March 2, 1961, in Bryan, Ohio to Walter E. “Bud” and Marguerite Koch. After graduating from Bryan High in 1979, he attended the University of Toledo (College of Pharmacy) where he received a Bachelor of Science in Pharmacy in 1984. Subsequently, he attended the University of Cincinnati (College of Medicine) where he received his Ph.D. in Pharmacology and Cell Biophysics in 1990 under the laboratory of ...
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Duke University
Duke University is a private research university in Durham, North Carolina. Founded by Methodists and Quakers in the present-day city of Trinity in 1838, the school moved to Durham in 1892. In 1924, tobacco and electric power industrialist James Buchanan Duke established The Duke Endowment and the institution changed its name to honor his deceased father, Washington Duke. The campus spans over on three contiguous sub-campuses in Durham, and a marine lab in Beaufort. The West Campus—designed largely by architect Julian Abele, an African American architect who graduated first in his class at the University of Pennsylvania School of Design—incorporates Gothic architecture with the Duke Chapel at the campus' center and highest point of elevation, is adjacent to the Medical Center. East Campus, away, home to all first-years, contains Georgian-style architecture. The university administers two concurrent schools in Asia, Duke-NUS Medical School in Singapore (e ...
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University Of Toledo
The University of Toledo (UToledo or UT) is a public research university in Toledo, Ohio. It is the northernmost campus of the University System of Ohio. The university also operates a Health Science campus, which includes the University of Toledo Medical Center, in the West Toledo neighborhood of Toledo; a satellite campus in the Scott Park neighborhood of Toledo; the Center for the Visual Arts is located in downtown Toledo at the Toledo Museum of Art; and a research and education facility, known as the Lake Erie Center, at Maumee Bay State Park. The university was founded in 1872 in downtown Toledo as the Toledo University of Arts and Trades. It closed after six years. The city of Toledo took it over, reopening it in 1884 as the Toledo Manual Training School. The vocational school was developed as a university through the late 1800s. In 1931 the university moved to its current location in the Ottawa neighborhood. Since its establishment, the university has physically exp ...
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International Society For Heart Research
The International Society for Heart Research began as an "International Study Group for Research in Cardiac Metabolism" in Dubrovnik in 1968; at the 1976 World Congress in Tokyo, it adopted the name "International Society for Heart Research". It currently has over 3,000 members and comprises 7 international Sections (Australasian, Chinese, European, Indian, Japanese, Latin American and North American). The current president is Dr. Yoshihiko Saito Nara. The Society A society is a group of individuals involved in persistent social interaction, or a large social group sharing the same spatial or social territory, typically subject to the same political authority and dominant cultural expectations. Socie ... publishes its own journal ('' Journal of Molecular and Cellular Cardiology'') and newsletter (Heart News and Views). The ISHR has developed a number of awards (Peter Harris Distinguished Scientist Award, Research Achievement Award, Outstanding Investigator Award, three ...
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American Heart Association
The American Heart Association (AHA) is a nonprofit organization in the United States that funds cardiovascular medical research, educates consumers on healthy living and fosters appropriate cardiac care in an effort to reduce disability and deaths caused by cardiovascular disease and stroke. Originally formed in New York City in 1924, it is currently headquartered in Dallas, Texas. The American Heart Association is a national voluntary health agency. They are known for publishinguidelineson cardiovascular disease and prevention, standards on basic life support, advanced cardiac life support (ACLS), and pediatric advanced life support (PALS), and in 2014 issued its first guidelines for preventing strokes in women. They are known also for operating a number of highly visible public service campaigns starting in the 1970s, and also operate a number of fundraising events. In 1994, the ''Chronicle of Philanthropy'', an industry publication, released a study that showed the American H ...
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Thomas Jefferson University
Thomas Jefferson University is a private research university in Philadelphia, Pennsylvania. Established in its earliest form in 1824, the university officially combined with Philadelphia University in 2017. To signify its heritage, the university sometimes carries the nomenclature ''Jefferson (Philadelphia University + Thomas Jefferson University)'' in its branding. It is classified among "R2: Doctoral Universities – High research activity". The university is named for U.S. Founding Father and president Thomas Jefferson. History Thomas Jefferson University was founded in 1824 and merged with another university located in same city, Philadelphia University, in 2017. Philadelphia University was originally known as Philadelphia Textile School when it was founded in 1884, and then Philadelphia Textile Institute for 20 years (1942 to 1961), Philadelphia College of Textiles & Science for 58 years (1962 to 1999), and Philadelphia University for 18 years (1999 to 2017), its final ...
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Robert Lefkowitz
Robert Joseph Lefkowitz (born April 15, 1943) is an American physician (internist and cardiologist) and biochemist. He is best known for his groundbreaking discoveries that reveal the inner workings of an important family G protein-coupled receptors, for which he was awarded the 2012 Nobel Prize for Chemistry with Brian Kobilka. He is currently an Investigator with the Howard Hughes Medical Institute as well as a James B. Duke Professor of Medicine and Professor of Biochemistry and Chemistry at Duke University. Early life Lefkowitz was born on April 15, 1943, in The Bronx, New York to Jewish parents Max and Rose Lefkowitz. Their families had emigrated to the United States from Poland in the late 19th century. After graduating from the Bronx High School of Science in 1959, he attended Columbia College from which he received a Bachelor of Arts in chemistry 1962. He graduated from Columbia University College of Physicians and Surgeons in 1966 with an M.D. Degree. After serving an ...
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Howard Hughes Medical Institute
The Howard Hughes Medical Institute (HHMI) is an American non-profit medical research organization based in Chevy Chase, Maryland. It was founded in 1953 by Howard Hughes, an American business magnate, investor, record-setting pilot, engineer, film director, and philanthropist, known during his lifetime as one of the most financially successful individuals in the world. It is one of the largest private funding organizations for biological and medical research in the United States. HHMI spends about $1 million per HHMI Investigator per year, which amounts to annual investment in biomedical research of about $825 million. The institute has an endowment of $22.6 billion, making it the second-wealthiest philanthropic organization in the United States and the second-best endowed medical research foundation in the world. HHMI is the former owner of the Hughes Aircraft Company – an American aerospace firm which was divested to various firms over time. History The institute was fo ...
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Duke University Medical Center
Duke University Hospital is a 957-acute care bed academic tertiary care facility located in Durham, North Carolina. Established in 1930, it is the flagship teaching hospital for the Duke University Health System, a network of physicians and hospitals serving Durham County and Wake County, North Carolina, and surrounding areas, as well as one of three Level I referral centers for the Research Triangle of North Carolina (the other two are UNC Hospitals in nearby Chapel Hill and WakeMed Raleigh in Raleigh). History 1924–1935: early years The institution traces its roots back to 1924, six years before the opening of the hospital, when James Buchanan Duke established the Duke Endowment to transform Duke University (then known as Trinity College) into the research university it is today. In 1925, Duke bequeathed $4 million to establish the medical school, nursing school, and hospital. Two years later, in 1927, construction began on the original hospital (now known as Duke S ...
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University Of Cincinnati
The University of Cincinnati (UC or Cincinnati) is a public research university in Cincinnati, Ohio. Founded in 1819 as Cincinnati College, it is the oldest institution of higher education in Cincinnati and has an annual enrollment of over 44,000 students, making it the second largest university in Ohio. It is part of the University System of Ohio. The university has four major campuses, with Cincinnati's main uptown campus and medical campus in the Heights and Corryville neighborhoods, and branch campuses in Batavia and Blue Ash, Ohio. The university has 14 constituent colleges, with programs in architecture, business, education, engineering, humanities, the sciences, law, music, and medicine. The medical college includes a leading teaching hospital and several biomedical research laboratories, with developments made including a live polio vaccine and diphenhydramine. UC was also the first university to implement a co-operative education (co-op) model. The university is accre ...
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Bryan High School (Bryan, Ohio)
Bryan High School is a public high school in Bryan, Ohio. It is the only high school in the Bryan City School District and serves students in grades 9 through 12. Athletic teams are known as the Golden Bears. They are members of the Northwest Ohio Athletic League and are the largest school participating in the league. As of the 2021–22 school year, enrollment is 546 students. Athletics State championships * Baseball – 1975 * Boys cross country – 1995 * Girls bowling – 2020 Notable alumni * Chris Carpenter (baseball, born 1985), Chris Carpenter, professional baseball player in Major League Baseball * Steve Fireovid, professional baseball player in Major League Baseball * Matt Wisler, professional baseball player in Major League Baseball References External links

* {{Authority control High schools in Williams County, Ohio Public high schools in Ohio Bryan, Ohio, High School ...
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G Protein-coupled Receptor
G protein-coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptors, and G protein-linked receptors (GPLR), form a large group of evolutionarily-related proteins that are cell surface receptors that detect molecules outside the cell and activate cellular responses. Coupling with G proteins, they are called seven-transmembrane receptors because they pass through the cell membrane seven times. Text was copied from this source, which is available under Attribution 2.5 Generic (CC BY 2.5) license. Ligands can bind either to extracellular N-terminus and loops (e.g. glutamate receptors) or to the binding site within transmembrane helices (Rhodopsin-like family). They are all activated by agonists although a spontaneous auto-activation of an empty receptor can also be observed. G protein-coupled receptors are found only in eukaryotes, including yeast, choanoflagellates, and ...
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Translational Medicine
Translational medicine (often called translational science, of which it is a form) is defined by the European Society for Translational Medicine as "an interdisciplinary branch of the biomedical field supported by three main pillars: benchside, bedside, and community". The goal of translational medicine is to combine disciplines, resources, expertise, and techniques within these pillars to promote enhancements in prevention, diagnosis, and therapies. Accordingly, translational medicine is a highly interdisciplinary field, the primary goal of which is to coalesce assets of various natures within the individual pillars in order to improve the global healthcare system significantly. History Translational medicine is a rapidly growing discipline in biomedical research and aims to expedite the discovery of new diagnostic tools and treatments by using a multi-disciplinary, highly collaborative, "bench-to-bedside" approach. Within public health, translational medicine is focused on ensur ...
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