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Duke University Hospital is a 957-acute care bed academic
tertiary care Health care or healthcare is the improvement of health via the prevention, diagnosis, treatment, amelioration or cure of disease, illness, injury, and other physical and mental impairments in people. Health care is delivered by health profess ...
facility located in
Durham, North Carolina Durham ( ) is a city in the U.S. state of North Carolina and the county seat of Durham County, North Carolina, Durham County. Small portions of the city limits extend into Orange County, North Carolina, Orange County and Wake County, North Carol ...
. Established in 1930, it is the flagship
teaching hospital A teaching hospital is a hospital or medical centre that provides medical education and training to future and current health professionals. Teaching hospitals are almost always affiliated with one or more universities and are often co-located ...
for the
Duke University Health System The Duke University Health System combines the Duke University School of Medicine, the Duke University School of Nursing, the Duke Clinic, and the member hospitals into a system of research, clinical care, and education. Member hospitals Duke ...
, a network of physicians and hospitals serving Durham County and
Wake County, North Carolina Wake County is located in the U.S. state of North Carolina. In the 2020 census, its population was 1,129,410, making it North Carolina's most-populous county. From July 2005 to July 2006, Wake County was the 9th-fastest growing county in the U ...
, and surrounding areas, as well as one of three Level I referral centers for the
Research Triangle The Research Triangle, or simply The Triangle, are both common nicknames for a metropolitan area in the Piedmont region of North Carolina in the United States, anchored by the cities of Raleigh and Durham and the town of Chapel Hill, home to ...
of North Carolina (the other two are
UNC Hospitals UNC Medical Center (UNCMC) is a 905-bed non-profit, nationally ranked, public, research and academic medical center located in Chapel Hill, North Carolina, providing tertiary care for the Research Triangle, surrounding areas and North Carolina. The ...
in nearby
Chapel Hill Chapel Hill or Chapelhill may refer to: Places Antarctica * Chapel Hill (Antarctica) Australia *Chapel Hill, Queensland, a suburb of Brisbane *Chapel Hill, South Australia, in the Mount Barker council area Canada * Chapel Hill, Ottawa, a neighbo ...
and WakeMed Raleigh in
Raleigh Raleigh (; ) is the capital city of the state of North Carolina and the seat of Wake County in the United States. It is the second-most populous city in North Carolina, after Charlotte. Raleigh is the tenth-most populous city in the Southeas ...
).


History


1924–1935: early years

The institution traces its roots back to 1924, six years before the opening of the hospital, when
James Buchanan Duke James Buchanan Duke (December 23, 1856 – October 10, 1925) was an American tobacco and electric power industrialist best known for the introduction of modern cigarette manufacture and marketing, and his involvement with Duke University. ...
established the
Duke Endowment The Duke Endowment is a private foundation established in 1924 by industrialist and philanthropist James B. Duke. It supports selected programs of higher education, health care, children's welfare, and spiritual life in North Carolina and South ...
to transform
Duke University Duke University is a private research university in Durham, North Carolina. Founded by Methodists and Quakers in the present-day city of Trinity in 1838, the school moved to Durham in 1892. In 1924, tobacco and electric power industrialist James ...
(then known as Trinity College) into the
research university A research university or a research-intensive university is a university that is committed to research as a central part of its mission. They are the most important sites at which knowledge production occurs, along with "intergenerational kno ...
it is today. In 1925, Duke bequeathed $4 million to establish the
medical school A medical school is a tertiary educational institution, or part of such an institution, that teaches medicine, and awards a professional degree for physicians. Such medical degrees include the Bachelor of Medicine, Bachelor of Surgery (MBBS, M ...
,
nursing school Nursing is a profession within the health care sector focused on the care of individuals, families, and communities so they may attain, maintain, or recover optimal health and quality of life. Nurses may be differentiated from other health ca ...
, and hospital. Two years later, in 1927, construction began on the original hospital (now known as Duke South), which opened on July 21, 1930, with 400 beds. In 1931, the hospital and medical school were officially dedicated on April 20 and the Private Diagnostic Clinic (Duke's in-house physician system) was organized on September 16. In 1935, less than five years after the hospital opened, the
American Medical Association The American Medical Association (AMA) is a professional association and lobbying group of physicians and medical students. Founded in 1847, it is headquartered in Chicago, Illinois. Membership was approximately 240,000 in 2016. The AMA's state ...
ranked Duke among the top 20 of medical schools in the country.


1936–1969: a number of firsts

In 1936, a team of physicians led by Dr.
Julian Deryl Hart Julian Deryl Hart (August 27, 1894 – June 1, 1980) served as President of Duke University from 1960 to 1963. Previously, he was the Professor and Chairman of the Department of Surgery at Duke. During his presidency of three years, he planned a ...
introduced
ultraviolet light Ultraviolet (UV) is a form of electromagnetic radiation with wavelength from 10 nm (with a corresponding frequency around 30  PHz) to 400 nm (750  THz), shorter than that of visible light, but longer than X-rays. UV radiation i ...
to kill germs in the operating room as a way to combat post-operative
staph infection A staphylococcal infection or staph infection is an infection caused by members of the ''Staphylococcus'' genus of bacteria. These bacteria commonly inhabit the skin and nose where they are innocuous, but may enter the body through cuts or abrasio ...
s, greatly reducing the number of infections and related deaths. In the same year, the hospital established the nation's first
brain tumor A brain tumor occurs when abnormal cells form within the brain. There are two main types of tumors: malignant tumors and benign (non-cancerous) tumors. These can be further classified as primary tumors, which start within the brain, and seconda ...
program, launching what would become one of the world's most renowned programs in the field of
cancer Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal b ...
treatment. In 1937, Joseph Beard developed a
vaccine A vaccine is a biological Dosage form, preparation that provides active acquired immunity to a particular infectious disease, infectious or cancer, malignant disease. The safety and effectiveness of vaccines has been widely studied and verifie ...
against equine encephalomyelitis, one of the first known vaccines to combat the
mosquito Mosquitoes (or mosquitos) are members of a group of almost 3,600 species of small flies within the family Culicidae (from the Latin ''culex'' meaning " gnat"). The word "mosquito" (formed by ''mosca'' and diminutive ''-ito'') is Spanish for "li ...
-carried disease. In 1940, the hospital made its first expansion, adding a new wing to the original building. In 1946, the Division of Thoracic Surgery, today the Duke Division of Cardiovascular and Thoracic Surgery, was organized by
Josiah Charles Trent Josiah Charles Trent (August 7, 1914 December 10, 1948) was an American surgeon and a historian of medicine. He is notable for his collection of rare books and manuscripts documenting the history of western medicine. After his death, his widow, M ...
. In 1947, the Bell Research Building became the first freestanding building on the hospital campus. In 1954, the Duke
Poison Control Center A poison control center is a medical service that is able to provide immediate, free, and expert treatment advice and assistance over the telephone in case of exposure to poisonous or hazardous substances. Poison control centers answer questions ...
was organized, becoming one of the first two organized in the country. In 1955, psychiatrist Ewald W. Busse established the Duke University Center for Aging, the first research center of its kind in the nation. Currently the oldest continuously operating facility in the United States, this center has pioneered long-term studies of health problems among seniors. In 1956, Duke surgeons performed the first
cardiac surgery Cardiac surgery, or cardiovascular surgery, is surgery on the heart or great vessels performed by cardiac surgeons. It is often used to treat complications of ischemic heart disease (for example, with coronary artery bypass grafting); to corr ...
using systemic
hypothermia Hypothermia is defined as a body core temperature below in humans. Symptoms depend on the temperature. In mild hypothermia, there is shivering and mental confusion. In moderate hypothermia, shivering stops and confusion increases. In severe h ...
to bring a patient's body temperature down to less than 50
degree Degree may refer to: As a unit of measurement * Degree (angle), a unit of angle measurement ** Degree of geographical latitude ** Degree of geographical longitude * Degree symbol (°), a notation used in science, engineering, and mathematics ...
s Fahrenheit in an effort to minimize tissue damage during lengthy surgeries. With the success of this experiment, systemic hypothermia has become standard procedure in all hospitals worldwide. In 1957, the hospital and medical school were renamed Duke University Medical Center. In 1958, Thelma Ingles, a professor and chair of the Department of Medical-Surgical Nursing, developed the clinical nursing specialist program, becoming the first master's program of its kind in the United States. The establishment of the nursing specialist program paved the way for advanced clinical knowledge in the delivery and teaching of the nursing field. The 1960s brought extraordinary firsts to Duke. In 1963, the first
African-American African Americans (also referred to as Black Americans and Afro-Americans) are an Race and ethnicity in the United States, ethnic group consisting of Americans with partial or total ancestry from sub-Saharan Africa. The term "African American ...
student was accepted to the prestigious medical school. Two years later, in 1965, the hospital established the first
physician assistant A physician assistant or physician associate (PA) is a type of Mid-level practitioner, mid-level health care provider. In North America PAs may diagnose illnesses, develop and manage treatment plans, prescribe medications, and may serve as a pri ...
program in the country. In 1966, Duke became the first medical center in the world to offer radio consultation with physicians in developing countries. This program, called Med-Aid (short for Medical Assistance for Isolated Doctors), met the critical needs of the physicians who lacked proper treatment. That same year, the Medical Scientist Training Program, a joint program leading to simultaneous M.D. and Ph.D
degree Degree may refer to: As a unit of measurement * Degree (angle), a unit of angle measurement ** Degree of geographical latitude ** Degree of geographical longitude * Degree symbol (°), a notation used in science, engineering, and mathematics ...
s, was established, becoming one of the first three in the nation. In 1969, the first recorded studies of human's abilities to function and work at pressures equal to a 1,000-foot (300 m) deep sea dive were conducted in the
hyperbaric chamber A diving chamber is a vessel for human occupation, which may have an entrance that can be sealed to hold an internal pressure significantly higher than ambient pressure, a pressurised gas system to control the internal pressure, and a supply of ...
.


1970–1989: a period of growth and expansion

With the dawn of the 1970s, Duke underwent a period of expansion that continued well into the 1980s. In December 1971, the Duke Comprehensive Cancer Center was established under the
National Cancer Act The "war on cancer" is the effort to find a cure for cancer by increased research to improve the understanding of cancer biology and the development of more effective cancer treatments, such as targeted drug therapies. The aim of such efforts is t ...
. Duke's cancer center, one of the first in the nation under this groundbreaking legislation, was officially designated as a "comprehensive" cancer center by the
National Cancer Institute The National Cancer Institute (NCI) coordinates the United States National Cancer Program and is part of the National Institutes of Health (NIH), which is one of eleven agencies that are part of the U.S. Department of Health and Human Services. ...
in 1973. That same year, the Duke Eye Center was dedicated and opened on November 8. In 1978, the Morris Cancer Research Building opened, giving researchers a place to study and find cures for the disease. During the 1970s, the hospital also faced two distinct unionization drives aimed at uniting the unskilled service workers of Duke Hospital. The 1974 and 1978 drives both ultimately failed, and the 1980s ushered in a twenty-year low in organizing and activism at the hospital. In 1980, Duke moved into its present $94.5 million facility (Duke North) on Erwin Road, located just north of its original location. In 1985, with the emergence of
AIDS Human immunodeficiency virus infection and acquired immunodeficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV), a retrovirus. Following initial infection an individual m ...
bringing alarm to the medical community, Duke became one of the first two hospitals to conduct human clinical trials on
AZT Zidovudine (ZDV), also known as azidothymidine (AZT), is an antiretroviral medication used to prevent and treat HIV/AIDS. It is generally recommended for use in combination with other antiretrovirals. It may be used to prevent mother-to-child ...
, the first drug to offer an improved quality of life in patients battling AIDS.


1990–present: accelerated growth and expansion

In the 1990s, the medical research at Duke reached the forefront for detection of ailments that can be treated with a larger success rate. In 1990, Duke
geneticist A geneticist is a biologist or physician who studies genetics, the science of genes, heredity, and variation of organisms. A geneticist can be employed as a scientist or a lecturer. Geneticists may perform general research on genetic processe ...
s invented a three-minute test to screen
newborn An infant or baby is the very young offspring of human beings. ''Infant'' (from the Latin word ''infans'', meaning 'unable to speak' or 'speechless') is a formal or specialised synonym for the common term ''baby''. The terms may also be used to ...
s for over 30
metabolic disease A metabolic disorder is a disorder that negatively alters the body's processing and distribution of macronutrients, such as proteins, fats, and carbohydrates. Metabolic disorders can happen when abnormal chemical reactions in the body alter the ...
s at one time. This practice has since become standard worldwide. In 1992, Duke's cancer center became the first hospital to develop an outpatient
bone marrow transplant Hematopoietic stem-cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood in order to replicate inside of a patient and to produce ...
program. That same year, the hospital performed its first lung and heart/lung transplants. The year 1994 marked the beginning of accelerated expansion for Duke. That year, the Levine Science Research Center and the Medical Sciences Research Center were opened. In addition, there were extensive renovations of the Duke Clinic (Duke South), additions to the Morris Cancer Research Building, a new Children's Health Center, a freestanding Ambulatory Care Center, and expanded parking options for visitors. In 1998, the
Duke University Health System The Duke University Health System combines the Duke University School of Medicine, the Duke University School of Nursing, the Duke Clinic, and the member hospitals into a system of research, clinical care, and education. Member hospitals Duke ...
was created with newly established partnerships with
Durham Regional Hospital Duke Regional Hospital (DRH), located in northern Durham, North Carolina is a general-services hospital that has been part of the Duke University Health System since 1998. The hospital has 369 beds and over 500 physicians on the medical staff, a ...
and Raleigh Community Hospital. That same year, the
National Institutes of Health The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late ...
partnered with Duke to offer the first joint master's of health science in clinical research degree. With this extraordinary partnership, the NIH became the first organization to offer a joint graduate degree program with a major university. In 2001, the hospital was the first to establish a center dedicated exclusively to
Cardiovascular The blood circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the entire body of a human or other vertebrate. It includes the cardiovascular system, or vascular system, tha ...
Magnetic Resonance Imaging Magnetic resonance imaging (MRI) is a medical imaging technique used in radiology to form pictures of the anatomy and the physiological processes of the body. MRI scanners use strong magnetic fields, magnetic field gradients, and radio wave ...
. In 2019, a team at the hospital became the first in the United States to transplant an adult heart into a recipient through a process known as donation after circulatory death. In 2019, the hospital began a major expansion project on its emergency department and behavioral health unit.


Notable alumni

* Heidi Wunderli-Allenspach (born 1947), Swiss biologist and first women rector of ETH Zurich


See also

*
Rebecca Buckley Rebecca Hatcher Buckley (born 1933) is a medical doctor who has conducted research in pediatric immunological diseases. Biography Buckley graduated from Duke University in 1954 with a bachelor's degree. She received her Doctor of Medicine in 1 ...


References


External links


Duke University Hospital
{{Coord, 36.0072, -78.9373, region:US-NC_type:landmark, display=title Hospital buildings completed in 1930 Hospital buildings completed in 1980
Hospital A hospital is a health care institution providing patient treatment with specialized health science and auxiliary healthcare staff and medical equipment. The best-known type of hospital is the general hospital, which typically has an emerge ...
Hospitals in Durham, North Carolina Teaching hospitals in North Carolina Trauma centers 1930 establishments in North Carolina