W. Clark Still
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W. Clark Still
William Clark Still (born 1946) is an American organic chemistry, organic chemist. As a distinguished professor at Columbia University, Clark Still made significant contributions to the field of organic chemistry, particularly in the areas of natural product synthesis, reaction development, conformational analysis, macrocyclic stereocontrol, and computational chemistry. Still and coworkers also developed the purification technique known as flash column chromatography which is widely used for the purification of organic compounds. Major contributions Total synthesis Periplanone B In 1979, Still reported the first total synthesis of periplanone B, the potent sex pheromone of the American cockroach. Although the structural connectivity of this compound had been established spectroscopically, Still's synthesis confirmed the relative stereochemical relationships present in this natural product. A key step in this synthesis makes use of an anionic oxy-Cope rearrangement to form th ...
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Augusta, Georgia
Augusta ( ), officially Augusta–Richmond County, is a consolidated city-county on the central eastern border of the U.S. state of Georgia (U.S. state), Georgia. The city lies across the Savannah River from South Carolina at the head of its navigable portion. Georgia's Georgia (U.S. state)#Major cities (2017), third-largest city after Atlanta and Columbus, Georgia, Columbus, Augusta is located in the Fall Line section of the state. According to the U.S. Census Bureau, Augusta–Richmond County had a 2020 population of 202,081, not counting the unconsolidated cities of Blythe, Georgia, Blythe and Hephzibah, Georgia, Hephzibah. It is the List of United States cities by population, 116th largest city in the United States. The process of consolidation between the City of Augusta and Richmond County, Georgia, Richmond County began with a 1995 referendum in the two jurisdictions. The merger was completed on July 1, 1996. Augusta is the principal city of the Augusta metropolitan area. In ...
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