Virus-Serum-Toxin Act
The Virus-Serum-Toxin Act or VSTA (P.L. 430 of 1913, as amended; 21 U.S.C. 151-158) was United States Federal legislation designed to protect farmers and livestock raisers by regulating the quality of vaccines and point-of-care diagnostics for animals. Initially, the Virus-Serum-Toxin Act was created due to significant losses from unregulated manufacture and distribution of anti-hog cholera serum. The Act's intended purpose is to ensure the safe and efficient supply of animal vaccines and other biological products. The United States Secretary of Agriculture is responsible for licensing and regulating the manufacture, importation, and exportation of affected agents. The act and its applicable guidelines are managed by the Animal and Plant Health Inspection Service (APHIS) of the United States Department of Agriculture (USDA). History The Virus-Serum-Toxin Act was enacted in 1913. During this time, a USDA official stated that the bill was crucial "to protect the farmer and stock raise ...
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Vaccine
A vaccine is a biological Dosage form, preparation that provides active acquired immunity to a particular infectious disease, infectious or cancer, malignant disease. The safety and effectiveness of vaccines has been widely studied and verified. A vaccine typically contains an agent that resembles a disease-causing microorganism and is often made from weakened or Antigen, killed forms of the microbe, its toxins, or one of its surface proteins. The agent stimulates the body's immune system to recognize the agent as a threat, destroy it, and to further recognize and destroy any of the microorganisms associated with that agent that it may encounter in the future. Vaccines can be prophylaxis, prophylactic (to prevent or ameliorate the effects of a future infection by a natural or "wild" pathogen), or therapeutic vaccines, therapeutic (to fight a disease that has already occurred, such as cancer vaccine, cancer).
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Toxin
A toxin is a naturally occurring organic poison produced by metabolic activities of living cells or organisms. Toxins occur especially as a protein or conjugated protein. The term toxin was first used by organic chemist Ludwig Brieger (1849–1919) and is derived from the word toxic. Toxins can be small molecules, peptides, or proteins that are capable of causing disease on contact with or absorption by body tissues interacting with biological macromolecules such as enzymes or cellular receptors. Toxins vary greatly in their toxicity, ranging from usually minor (such as a bee sting) to potentially fatal even at extremely low doses (such as botulinum toxin). Toxins are largely secondary metabolites, which are organic compounds that are not directly involved in an organism's growth, development, or reproduction, instead often aiding it in matters of defense. Terminology Toxins are often distinguished from other chemical agents strictly based on their biological origin. Le ...
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United States Federal Agriculture Legislation
United may refer to: Places * United, Pennsylvania, an unincorporated community * United, West Virginia, an unincorporated community Arts and entertainment Films * ''United'' (2003 film), a Norwegian film * ''United'' (2011 film), a BBC Two film Literature * ''United!'' (novel), a 1973 children's novel by Michael Hardcastle Music * United (band), Japanese thrash metal band formed in 1981 Albums * ''United'' (Commodores album), 1986 * ''United'' (Dream Evil album), 2006 * ''United'' (Marvin Gaye and Tammi Terrell album), 1967 * ''United'' (Marian Gold album), 1996 * ''United'' (Phoenix album), 2000 * ''United'' (Woody Shaw album), 1981 Songs * "United" (Judas Priest song), 1980 * "United" (Prince Ital Joe and Marky Mark song), 1994 * "United" (Robbie Williams song), 2000 * "United", a song by Danish duo Nik & Jay featuring Lisa Rowe Television * ''United'' (TV series), a 1990 BBC Two documentary series * ''United!'', a soap opera that aired on BBC One from 1965-19 ...
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62nd United States Congress
The 62nd United States Congress was a meeting of the legislative branch of the United States federal government, composed of the United States Senate and the United States House of Representatives. It met in Washington, DC from March 4, 1911, to March 4, 1913, during the final two years of William H. Taft's presidency. The apportionment of seats in the House of Representatives was based on the Twelfth Census of the United States in 1900. Additional House seats were assigned to the two new states of New Mexico and Arizona. The size of the House was to be 435 starting with the new Congress coming into session in 1913. The Senate had a Republican majority, and the House had a Democratic majority. Major events * April 27, 1911: Following the resignation and death of William P. Frye, a compromise is reached to rotate the office of President pro tempore of the United States Senate. * October 30, 1912: Vice President James S. Sherman died. Major legislation * August 8, 1911: ...
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1913 In American Law
Events January * January 5 – First Balkan War: Battle of Lemnos – Greek admiral Pavlos Kountouriotis forces the Turkish fleet to retreat to its base within the Dardanelles, from which it will not venture for the rest of the war. * January 13 – Edward Carson founds the (first) Ulster Volunteer Force, by unifying several existing loyalist militias to resist home rule for Ireland. * January 23 – 1913 Ottoman coup d'état: Ismail Enver comes to power. * January – Stalin (whose first article using this name is published this month) travels to Vienna to carry out research. Until he leaves on February 16 the city is home simultaneously to him, Hitler, Trotsky and Tito alongside Berg, Freud and Jung and Ludwig and Paul Wittgenstein. February * February 1 – New York City's Grand Central Terminal, having been rebuilt, reopens as the world's largest railroad station. * February 3 – The 16th Amendment to the United States Constitution ...
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John Clifford (veterinarian)
John Clifford may refer to: * John Clifford, 7th Baron de Clifford (1389–1422), also 7th Lord of Skipton * John Clifford, 9th Baron de Clifford (1435–1461), also 9th Lord of Skipton, Lancastrian military leader during the Wars of the Roses *John David Clifford, Jr. (1887–1956), United States District Judge for the District of Maine *John H. Clifford (1809–1876), Governor of Massachusetts * John Clifford (minister) (1836–1923), British nonconformist minister and politician *J. R. Clifford or John Robert Clifford (1848–1933), West Virginian African-American attorney *John R. Clifford, USDA Chief Veterinarian *John Clifford (choreographer) *Johnny Clifford John Clifford (1934 – 19 October 2007) was an Irish hurler and hurling coach. After All-Ireland Championship victories as a player and manager during a five-decade association with the Cork senior hurling team, he is regarded as a "Cork le ...

Mad Cow Disease
Bovine spongiform encephalopathy (BSE), commonly known as mad cow disease, is an incurable and invariably fatal neurodegenerative disease of cattle. Symptoms include abnormal behavior, trouble walking, and weight loss. Later in the course of the disease the cow becomes unable to function normally. There is conflicting information around the time between infection and onset of symptoms. In 2002, the WHO suggested it to be approximately four to five years. Time from onset of symptoms to death is generally weeks to months. Spread to humans is believed to result in variant Creutzfeldt–Jakob disease (vCJD). As of 2018, a total of 231 cases of vCJD had been reported globally. BSE is thought to be due to an infection by a misfolded protein, known as a prion. Cattle are believed to have been infected by being fed meat-and-bone meal (MBM) that contained either the remains of cattle who spontaneously developed the disease or scrapie-infected sheep products. The outbreak increased th ...
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Bovine Spongiform Encephalopathy
Bovine spongiform encephalopathy (BSE), commonly known as mad cow disease, is an incurable and invariably fatal neurodegenerative disease of cattle. Symptoms include abnormal behavior, trouble walking, and weight loss. Later in the course of the disease the cow becomes unable to function normally. There is conflicting information around the time between infection and onset of symptoms. In 2002, the WHO suggested it to be approximately four to five years. Time from onset of symptoms to death is generally weeks to months. Spread to humans is believed to result in variant Creutzfeldt–Jakob disease (vCJD). As of 2018, a total of 231 cases of vCJD had been reported globally. BSE is thought to be due to an infection by a misfolded protein, known as a prion. Cattle are believed to have been infected by being fed meat-and-bone meal (MBM) that contained either the remains of cattle who spontaneously developed the disease or scrapie-infected sheep products. The outbreak increased th ...
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Federal Food, Drug, And Cosmetic Act
The United States Federal Food, Drug, and Cosmetic Act (abbreviated as FFDCA, FDCA, or FD&C) is a set of laws passed by the United States Congress in 1938 giving authority to the U.S. Food and Drug Administration (FDA) to oversee the safety of food, drugs, medical devices, and cosmetics. A principal author of this law was Royal S. Copeland, a three-term U.S. senator from New York. In 1968, the Electronic Product Radiation Control provisions were added to the FD&C. Also in that year the FDA formed the Drug Efficacy Study Implementation (DESI) to incorporate into FD&C regulations the recommendations from a National Academy of Sciences investigation of effectiveness of previously marketed drugs. The act has been amended many times, most recently to add requirements about bioterrorism preparations. The introduction of this act was influenced by the death of more than 100 patients due to elixir sulfanilamide, a sulfanilamide medication where the toxic solvent diethylene glycol was us ...
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Serum
Serum may refer to: *Serum (blood), plasma from which the clotting proteins have been removed **Antiserum, blood serum with specific antibodies for passive immunity * Serous fluid, any clear bodily fluid * Truth serum, a drug that is likely to make people tell the truth *Gary Serum (born 1956), American baseball player *Serum, a software synthesizer VST created by Steve Duda See also *Sera (other) Sera may refer to: People * Ryu Sera (born 1987), South Korean singer * Sera Cahoone (born 1975), Seattle-based singer and musician Places * Sera, Hiroshima, a town in Japan * Sera District, Hiroshima * Sera Monastery, Lhasa, Tibet Me ...

United States Secretary Of Agriculture
The United States secretary of agriculture is the head of the United States Department of Agriculture. The position carries similar responsibilities to those of agriculture ministers in other governments. The department includes several organizations. The 297,000 mi2 (770,000 km2) of national forests and grasslands are managed by the United States Forest Service. The safety of food produced and sold in the United States is ensured by the United States Food Safety and Inspection Service. The Food Stamp Program works with the states to provide food to low-income people. Secretary of Agriculture is a Level I position in the Executive Schedule, thus earning a salary of US$221,400, as of January 2021. Since February 24, 2021, the current secretary is Tom Vilsack, who had previously served as the 30th secretary of agriculture in the Obama administration. List of secretaries of agriculture When the Department of Agriculture was established in 1862, its executive was ...
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Virus
A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsky's 1892 article describing a non-bacterial pathogen infecting tobacco plants and the discovery of the tobacco mosaic virus by Martinus Beijerinck in 1898,Dimmock p. 4 more than 9,000 virus species have been described in detail of the millions of types of viruses in the environment. Viruses are found in almost every ecosystem on Earth and are the most numerous type of biological entity. The study of viruses is known as virology, a subspeciality of microbiology. When infected, a host cell is often forced to rapidly produce thousands of copies of the original virus. When not inside an infected cell or in the process of infecting a cell, viruses exist in the form of independent particles, or ''virions'', consisting of (i) the genetic material, i. ...
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