Viridicatumtoxin

	Viridicatumtoxin Viridicatumtoxin A (also simply called viridicatumtoxin) is a fungus-derived tetracycline-like antibiotic, whose chemical structure was determined in 1976. It is found in '' Penicillium viridicatum'', '' Penicillium aethiopicum'', among other fungi. Like viridicatumtoxin B, viridicatumtoxin A inhibits growth of ''Staphylococcus aureus'', including methicillin resistant ''S. aureus'' and quinolone Quinolone may refer to: * 2-Quinolone * 4-Quinolone * Quinolone antibiotic A quinolone antibiotic is a member of a large group of broad-spectrum bacteriocidals that share a bicyclic core structure related to the substance 4-quinolone. They ...-resistant ''S. aureus'', with an activity 8 to 64 times greater than that of tetracycline. References Tetracycline antibiotics Cyclohexenes Spiro compounds {{antibiotic-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Viridicatumtoxin B Viridicatumtoxin B is a fungus-derived tetracycline-like antibiotic discovered in 2008. It was isolated from small amounts of penicillium fungi. A synthetic structure matching that of natural viridicatumtoxin B makes possible synthetic variants that match or surpass its antibiotic potency. Analogs lacking a hydroxyl group were even more effective than the original against Gram-positive bacteria. Concerns about solubility, biodegradation, availability and other issues must be resolved before clinical development begins. History The substance was first isolated from the mycelium of liquid fermentation cultures of '' Penicillium'' species FR11. Structure Based on mass spectrometry and nuclear magnetic resonance data, the substance was originally thought to be the 11a',12'- epoxide, but the structure was later revised. Effects Viridicatumtoxin B inhibited the growth of ''Staphylococcus aureus'', including methicillin resistant ''S. aureus'' and quinolone-resistant ' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Penicillium Viridicatum ''Penicillium viridicatum'' is a psychrophilic species of fungus in the genus , penicillic acid Penicillic acid is a mycotoxin that is produced by ''Aspergillus flavus'' and ''Penicillium roqueforti'' mold. It is also the major product of acid degradation of penicillin. Its first practical synthesis was reported in 1947 by Ralph Raphael, wh ... and citrinin. ''Penicillium viridicatum'' can spoil grapes and melons. Further reading * * * * * * * * * * * References {{Taxonbar, from=Q22285993 viridicatum Fungi described in 1911 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Penicillium Aethiopicum ''Penicillium aethiopicum'' is a fungus species of the genus of '' Penicillium''. ''Penicillium aethiopicum'' produces viridicatumtoxin Viridicatumtoxin A (also simply called viridicatumtoxin) is a fungus-derived tetracycline-like antibiotic, whose chemical structure was determined in 1976. It is found in '' Penicillium viridicatum'', '' Penicillium aethiopicum'', among other f ... and griseofulvin, two structurally interesting polyketides. See also * List of Penicillium species References Further reading Polyphasic Taxonomy of subgenus penicilliumJ.C. Frisvad & R. A. Samson aethiopicum Fungi described in 1989 {{Eurotiomycetes-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
picture info	Fungus A fungus ( : fungi or funguses) is any member of the group of eukaryotic organisms that includes microorganisms such as yeasts and molds, as well as the more familiar mushrooms. These organisms are classified as a kingdom, separately from the other eukaryotic kingdoms, which by one traditional classification include Plantae, Animalia, Protozoa, and Chromista. A characteristic that places fungi in a different kingdom from plants, bacteria, and some protists is chitin in their cell walls. Fungi, like animals, are heterotrophs; they acquire their food by absorbing dissolved molecules, typically by secreting digestive enzymes into their environment. Fungi do not photosynthesize. Growth is their means of mobility, except for spores (a few of which are flagellated), which may travel through the air or water. Fungi are the principal decomposers in ecological systems. These and other differences place fungi in a single group of related organisms, named the ''Eumycota'' (''true f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]