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Umatilla Virus
''Umatilla virus'' (UMAV) is a dsRNA virus in the family '' Reoviridae'', subfamily ''Sedoreovirinae'', and the genus ''Orbivirus''. This arbovirus was first isolated in 1969 in Umatilla County, Oregon in a group of ''Culex pipiens'' mosquitoes. The viral host is the '' Passer domesticus'' bird with the vectors being '' Culex'' mosquitoes. Virus structure According to the Baltimore classification, '' Reoviridae'' are in Group III due to their dsRNA genome. This family of viruses have a linear and segmented genomic arrangement and they lack a lipid envelope. Opposed to having a lipid envelope, these viruses pack their genome into a multi-layered capsid; the outer capsid being T=13 and the inner T=2. The family is divided into two subfamilies and UMAV belongs to ''Sedoreovirinae''. This subfamily lacks turrets and therefore has a smooth surface. UMAV is in the genus ''Orbivirus ''Orbivirus'' is a genus of double-stranded RNA viruses in the family ''Reoviridae'' and subfamily ...
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Reoviridae
''Reoviridae'' is a family of double-stranded RNA viruses. Member viruses have a wide host range, including vertebrates, invertebrates, plants, protists and fungi. They lack lipid envelopes and package their segmented genome within multi-layered capsids. Lack of a lipid envelope has allowed three-dimensional structures of these large complex viruses (diameter ∼60–100 nm) to be obtained, revealing a structural and likely evolutionary relationship to the cystovirus family of bacteriophage. There are currently 97 species in this family, divided among 15 genera in two subfamilies. Reoviruses can affect the gastrointestinal system (such as rotaviruses) and respiratory tract. The name "reo-" is an acronym for "''r''espiratory ''e''nteric ''o''rphan" viruses''.'' The term "orphan virus" refers to the fact that some of these viruses have been observed not associated with any known disease. Even though viruses in the family ''Reoviridae'' have more recently been identified with vario ...
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Sedoreovirinae
''Sedoreovirinae'' (''sedo'' = smooth) is a subfamily of the ''Reoviridae'' family of viruses. Viruses in this subfamily are distinguished by the absence of a turreted protein on the inner capsid to produce a smooth surface. Characteristics Like other members of the ''Reoviridae'' family, viruses of the ''Sedoreovirinae'' subfamily are made of naked, icosahedral capsids containing 10-12 segments of linear double-stranded RNA (dsRNA). The Baltimore System of viral classification categorizes ''Reoviridae'' in Group III. Importance Viruses classified in the ''Sedoreovirinae'' subfamily infect a wide range of plants and animals, including some that can infect humans. There is not only the potential of a few of these viruses to cause human disease, but also to reduce the supply of crops and livestock. Viruses Genus ''Cardoreovirus'' '' Eriocheir sinensis reovirus'' was isolated out of a Chinese mitten crab ('' Eriocheir sinensis''). No currently known associated disease. Genus ''Mi ...
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Orbivirus
''Orbivirus'' is a genus of double-stranded RNA viruses in the family ''Reoviridae'' and subfamily ''Sedoreovirinae''. Unlike other reoviruses, orbiviruses are arboviruses. They can infect and replicate within a wide range of arthropod and vertebrate hosts. Orbiviruses are named after their characteristic doughnut-shaped capsomers (''orbis'' in Latin means ring). Many orbiviruses are transmitted by ticks or haematophagus insect vectors (''Culicoides'', mosquitoes and sand flies) and have a wide host range that includes cattle, goats and sheep, wild ruminants, equids, camelids, marsupials, sloths, bats, birds, large canine and feline carnivores, and humans. The three economically most important orbiviruses are ''Bluetongue virus'', ''African horse sickness virus'', and ''Epizootic hemorrhagic disease virus'', all of which are transmitted by ''Culicoides'' species. The genus contains 22 species and at least 130 different serotypes. History In 1719, African horse sickness viru ...
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Passer Domesticus
The house sparrow (''Passer domesticus'') is a bird of the sparrow family Passeridae, found in most parts of the world. It is a small bird that has a typical length of and a mass of . Females and young birds are coloured pale brown and grey, and males have brighter black, white, and brown markings. One of about 25 species in the genus ''Passer'', the house sparrow is native to most of Europe, the Mediterranean Basin, and a large part of Asia. Its intentional or accidental introductions to many regions, including parts of Australasia, Africa, and the Americas, make it the most widely distributed wild bird. The house sparrow is strongly associated with human habitation, and can live in urban or rural settings. Though found in widely varied habitats and climates, it typically avoids extensive woodlands, grasslands, and deserts away from human development. It feeds mostly on the seeds of grains and weeds, but it is an opportunistic eater and commonly eats insects and many othe ...
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Culex
''Culex'' is a genus of mosquitoes, several species of which serve as vectors of one or more important diseases of birds, humans, and other animals. The diseases they vector include arbovirus infections such as West Nile virus, Japanese encephalitis, or St. Louis encephalitis, but also filariasis and avian malaria. They occur worldwide except for the extreme northern parts of the temperate zone, and are the most common form of mosquito encountered in some major U.S. cities, such as Los Angeles. Etymology In naming this genus, Carl Linnaeus appropriated the nonspecific Latin term for a midge or gnat: '. Description Depending on the species, the adult ''Culex'' mosquito may measure from . The adult morphology is typical of flies in the suborder Nematocera with the head, thorax, and abdomen clearly defined and the two forewings held horizontally over the abdomen when at rest. As in all Diptera capable of flight, the second pair of wings is reduced and modified into tiny, incon ...
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Baltimore Classification
Baltimore classification is a system used to classify viruses based on their manner of messenger RNA (mRNA) synthesis. By organizing viruses based on their manner of mRNA production, it is possible to study viruses that behave similarly as a distinct group. Seven Baltimore groups are described that take into consideration whether the viral genome is made of deoxyribonucleic acid (DNA) or ribonucleic acid (RNA), whether the genome is single- or double-stranded, and whether the sense of a single-stranded RNA genome is positive or negative. Baltimore classification also closely corresponds to the manner of replicating the genome, so Baltimore classification is useful for grouping viruses together for both transcription and replication. Certain subjects pertaining to viruses are associated with multiple, specific Baltimore groups, such as specific forms of translation of mRNA and the host range of different types of viruses. Structural characteristics such as the shape of the vir ...
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Double-stranded RNA Viruses
Double-stranded RNA viruses (dsRNA viruses) are a polyphyletic group of viruses that have double-stranded genomes made of ribonucleic acid. The double-stranded genome is used to transcribe a positive-strand RNA by the viral RNA-dependent RNA polymerase (RdRp). The positive-strand RNA may be used as messenger RNA (mRNA) which can be translated into viral proteins by the host cell's ribosomes. The positive-strand RNA can also be replicated by the RdRp to create a new double-stranded viral genome. Double-stranded RNA viruses are classified in two separate phyla ''Duplornaviricota'' and ''Pisuviricota'' (specifically class ''Duplopiviricetes''), which are in the kingdom ''Orthornavirae'' and realm ''Riboviria''. The two groups do not share a common dsRNA virus ancestor. Double-stranded RNA viruses evolved two separate times from positive-strand RNA viruses. In the Baltimore classification system, dsRNA viruses belong to Group III. Virus group members vary widely in host range (anim ...
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