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TIMM17A
Mitochondrial import inner membrane translocase subunit Tim17-A is an enzyme that in humans is encoded by the ''TIMM17A'' gene. See also * Mitochondria Inner Membrane Translocase * TIMM22 * TIMM23 * TIMM44 Mitochondrial import inner membrane translocase subunit TIM44 is an enzyme that in humans is encoded by the ''TIMM44'' gene. Interactions TIMM44 has been shown to interact with ARAF. See also * Mitochondria Inner Membrane Translocase * TIMM1 ... References Further reading * * * * * * {{gene-1-stub Mitochondrial proteins ...
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Translocase Of The Inner Membrane
The translocase of the inner membrane (TIM) is a complex of proteins found in the inner mitochondrial membrane of the mitochondria. Components of the TIM complex facilitate the translocation of proteins across the inner membrane and into the mitochondrial matrix. They also facilitate the insertion of proteins into the inner mitochondrial membrane, where they must reside in order to function, these mainly include members of the mitochondrial carrier family of proteins. The TIM23 complex The TIM23 complex facilitates translocation of matrix-targeted proteins into the mitochondrial matrix. These proteins contain a cleavable presequence. The TIM23 complex is made up of the subunits Tim17, Tim21 and Tim23, which are thought to contribute to the structural formation of the translocation channel that spans the inner membrane, and Tim44, which is a peripheral membrane protein. Tim44 is only weakly associated with Tim23 and is located on the matrix side of the inner membrane. At the openi ...
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TIMM22
Mitochondrial import inner membrane translocase subunit Tim22 is an enzyme that in humans is encoded by the ''TIMM22'' gene. See also * Mitochondria Inner Membrane Translocase * TIMM17A * TIMM23 * TIMM44 Mitochondrial import inner membrane translocase subunit TIM44 is an enzyme that in humans is encoded by the ''TIMM44'' gene. Interactions TIMM44 has been shown to interact with ARAF. See also * Mitochondria Inner Membrane Translocase * TIMM1 ... References Further reading * * * * * * * * {{gene-17-stub Mitochondrial proteins ...
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TIMM23
Mitochondrial import inner membrane translocase subunit Tim23 is an enzyme that in humans is encoded by the ''TIMM23'' gene In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b .... See also * Mitochondria Inner Membrane Translocase * TIMM17A * TIMM22 * TIMM44 References Further reading * * * * * * * {{gene-10-stub Mitochondrial proteins ...
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TIMM44
Mitochondrial import inner membrane translocase subunit TIM44 is an enzyme that in humans is encoded by the ''TIMM44'' gene. Interactions TIMM44 has been shown to interact with ARAF. See also * Mitochondria Inner Membrane Translocase * TIMM17A * TIMM22 * TIMM23 Mitochondrial import inner membrane translocase subunit Tim23 is an enzyme that in humans is encoded by the ''TIMM23'' gene In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of ... References Further reading * * * * * * * External links PDBe-KBprovides an overview of all the structure information available in the PDB for Human Mitochondrial import inner membrane translocase subunit TIM44 {{gene-19-stub Mitochondrial proteins ...
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Enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. Almost all metabolic processes in the cell need enzyme catalysis in order to occur at rates fast enough to sustain life. Metabolic pathways depend upon enzymes to catalyze individual steps. The study of enzymes is called ''enzymology'' and the field of pseudoenzyme analysis recognizes that during evolution, some enzymes have lost the ability to carry out biological catalysis, which is often reflected in their amino acid sequences and unusual 'pseudocatalytic' properties. Enzymes are known to catalyze more than 5,000 biochemical reaction types. Other biocatalysts are catalytic RNA molecules, called ribozymes. Enzymes' specificity comes from their unique three-dimensional structures. Like all catalysts, enzymes increase the react ...
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Gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a basic unit of heredity and the molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and noncoding genes. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes (many different genes) as well as ...
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