TIMM44

	TIMM44 Mitochondrial import inner membrane translocase subunit TIM44 is an enzyme that in humans is encoded by the ''TIMM44'' gene. Interactions TIMM44 has been shown to Protein-protein interaction, interact with ARAF. See also * Translocase of the inner membrane, Mitochondria Inner Membrane Translocase * TIMM17A * TIMM22 * TIMM23 References Further reading * * * * * * * External links PDBe-KB provides an overview of all the structure information available in the PDB for Human Mitochondrial import inner membrane translocase subunit TIM44 {{gene-19-stub Mitochondrial proteins ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	ARAF Serine/threonine-protein kinase A-Raf or simply A-Raf is an enzyme that in humans is encoded by the ''ARAF'' gene. A-Raf is a member of the Raf kinase family of serine/threonine-specific protein kinases. Compared to the other members of this family (Raf-1 and B-Raf), very little is known about A-Raf. It seems to share many of the properties of the other isoforms, but its biological functions are not as thoroughly researched. All three Raf proteins are involved in the MAPK signaling pathway. There are several ways A-Raf is different from the other Raf kinases. A-Raf is the only steroid hormone-regulated Raf isoform. In addition, the A-Raf protein has amino acid substitutions in a negatively charged region upstream of the kinase domain (N-region). This could be responsible for its low basal activity. Like Raf-1 and B-Raf, A-Raf activates MEK proteins which causes the activation of ERK and ultimately leads to cell cycle progression and cell proliferation. All three Raf protei ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Translocase Of The Inner Membrane The translocase of the inner membrane (TIM) is a complex of proteins found in the inner mitochondrial membrane of the mitochondria. Components of the TIM complex facilitate the translocation of proteins across the inner membrane and into the mitochondrial matrix. They also facilitate the insertion of proteins into the inner mitochondrial membrane, where they must reside in order to function, these mainly include members of the mitochondrial carrier family of proteins. The TIM23 complex The TIM23 complex facilitates translocation of matrix-targeted proteins into the mitochondrial matrix. These proteins contain a cleavable presequence. The TIM23 complex is made up of the subunits Tim17, Tim21 and Tim23, which are thought to contribute to the structural formation of the translocation channel that spans the inner membrane, and Tim44, which is a peripheral membrane protein. Tim44 is only weakly associated with Tim23 and is located on the matrix side of the inner membrane. At the openin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	TIMM17A Mitochondrial import inner membrane translocase subunit Tim17-A is an enzyme that in humans is encoded by the ''TIMM17A'' gene. See also * Translocase of the inner membrane, Mitochondria Inner Membrane Translocase * TIMM22 * TIMM23 * TIMM44 References Further reading * * * * * * {{gene-1-stub Mitochondrial proteins ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	TIMM22 Mitochondrial import inner membrane translocase subunit Tim22 is an enzyme that in humans is encoded by the ''TIMM22'' gene. See also * Mitochondria Inner Membrane Translocase * TIMM17A * TIMM23 * TIMM44 Mitochondrial import inner membrane translocase subunit TIM44 is an enzyme that in humans is encoded by the ''TIMM44'' gene. Interactions TIMM44 has been shown to interact with ARAF. See also * Mitochondria Inner Membrane Translocase * TIMM1 ... References Further reading * * * * * * * * {{gene-17-stub Mitochondrial proteins ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	TIMM23 Mitochondrial import inner membrane translocase subunit Tim23 is an enzyme that in humans is encoded by the ''TIMM23'' gene. See also * Mitochondria Inner Membrane Translocase * TIMM17A * TIMM22 * TIMM44 Mitochondrial import inner membrane translocase subunit TIM44 is an enzyme that in humans is encoded by the ''TIMM44'' gene. Interactions TIMM44 has been shown to interact with ARAF. See also * Mitochondria Inner Membrane Translocase * TIMM1 ... References Further reading * * * * * * * {{gene-10-stub Mitochondrial proteins ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
picture info	Enzyme Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. Almost all metabolic processes in the cell need enzyme catalysis in order to occur at rates fast enough to sustain life. Metabolic pathways depend upon enzymes to catalyze individual steps. The study of enzymes is called ''enzymology'' and the field of pseudoenzyme analysis recognizes that during evolution, some enzymes have lost the ability to carry out biological catalysis, which is often reflected in their amino acid sequences and unusual 'pseudocatalytic' properties. Enzymes are known to catalyze more than 5,000 biochemical reaction types. Other biocatalysts are catalytic RNA molecules, called ribozymes. Enzymes' specificity comes from their unique three-dimensional structures. Like all catalysts, enzymes increase the reaction ra ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
picture info	Gene In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a basic unit of heredity and the molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and noncoding genes. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes (many different genes) as well as gen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]