Trichuris Trichiura
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Trichuris Trichiura
''Trichuris trichiura, Trichocephalus trichiuris'' or whipworm, is a parasitism, parasitic nematode, roundworm (a type of helminth) that causes trichuriasis (a type of helminthiasis which is one of the neglected tropical diseases) when it infects a human large intestine. It is commonly known as the ''whipworm'' which refers to the shape of the worm; it looks like a whip with wider "handles" at the posterior end. Life cycle The female ''T. trichiura'' produces 2,000–10,000 single-celled eggs per day. Eggs are deposited from human feces to soil where, after two to three weeks, they become embryonated and enter the "infective" stage. These embryonated infective eggs are ingested by hand-mouth or through formites and hatch in the human small intestine, exploiting the intestinal microflora as a stimulus to hatching. This is the location of growth and molting. The infective larvae penetrate the Intestinal villus, villi and continue to develop in the small intestine. The young wor ...
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Carl Linnaeus
Carl Linnaeus (; 23 May 1707 – 10 January 1778), also known after his ennoblement in 1761 as Carl von Linné Blunt (2004), p. 171. (), was a Swedish botanist, zoologist, taxonomist, and physician who formalised binomial nomenclature, the modern system of naming organisms. He is known as the "father of modern taxonomy". Many of his writings were in Latin; his name is rendered in Latin as and, after his 1761 ennoblement, as . Linnaeus was born in Råshult, the countryside of Småland, in southern Sweden. He received most of his higher education at Uppsala University and began giving lectures in botany there in 1730. He lived abroad between 1735 and 1738, where he studied and also published the first edition of his ' in the Netherlands. He then returned to Sweden where he became professor of medicine and botany at Uppsala. In the 1740s, he was sent on several journeys through Sweden to find and classify plants and animals. In the 1750s and 1760s, he continued to collect an ...
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Chromosome 18
Chromosome 18 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 18 spans about 80 million base pairs (the building material of DNA) and represents about 2.5 percent of the total DNA in cells. Genes Number of genes The following are some of the gene count estimates of human chromosome 18. Because researchers use different approaches to genome annotation their predictions of the number of genes on each chromosome varies (for technical details, see gene prediction). Among various projects, the collaborative consensus coding sequence project ( CCDS) takes an extremely conservative strategy. So CCDS's gene number prediction represents a lower bound on the total number of human protein-coding genes. Gene list The following is a partial list of genes on human chromosome 18. For complete list, see the link in the infobox on the right. Diseases and disorders The following diseases are some of those related to genes o ...
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Hygiene Hypothesis
In medicine, the hygiene hypothesis states that early childhood exposure to particular microorganisms (such as the gut flora and helminth parasites) protects against allergic diseases by contributing to the development of the immune system. In particular, a lack of exposure is thought to lead to defects in the establishment of immune tolerance. The time period for exposure begins ''in utero'' and ends at school age. While early versions of the hypothesis referred to exposure to microbes in general, updated versions apply to a specific set of microbial species that have co-evolved with humans. The updates have been given various names, including the microbiome depletion hypothesis, the microflora hypothesis, and the "old friends" hypothesis. There is a significant amount of evidence supporting the idea that lack of exposure to these microbes is linked to allergies or other conditions, although scientific disagreement still exists. The term "hygiene hypothesis" has been described ...
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Mebendazole
Mebendazole (MBZ), sold under the brand name Vermox among others, is a medication used to treat a number of parasitic worm infestations. This includes ascariasis, pinworm infection, hookworm infections, guinea worm infections, hydatid disease, and giardia, among others. It is taken by mouth. Mebendazole is usually well tolerated. Common side effects include headache, vomiting, and ringing in the ears. If used at large doses it may cause bone marrow suppression. It is unclear if it is safe in pregnancy. Mebendazole is a broad-spectrum antihelminthic agent of the benzimidazole type. Mebendazole came into use in 1971, after it was developed by Janssen Pharmaceutica in Belgium. It is on the World Health Organization's List of Essential Medicines. Mebendazole is available as a generic medication. Medical use Mebendazole is a highly effective, broad-spectrum antihelmintic indicated for the treatment of nematode infestations, including roundworm, hookworm, whipworm, threadworm (pinw ...
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Albendazole
Albendazole (also known as albendazolum) is a broad-spectrum anthelmintic and antiprotozoal agent of the benzimidazole type. It is used for the treatment of a variety of intestinal parasite infections, including ascariasis, pinworm infection, hookworm infection, trichuriasis, strongyloidiasis, taeniasis, clonorchiasis, opisthorchiasis, cutaneous larva migrans, giardiasis, and gnathostomiasis, among other diseases. Common side effects include nausea, abdominal pain, and headache. Rare but potentially serious side effects include bone marrow suppression which usually improves on discontinuing the medication. Liver inflammation has been reported and those with prior liver problems are at greater risk. It is pregnancy category C in the United States and category D in Australia, meaning it may cause harm if taken by pregnant women. Albendazole was developed in 1975. It is on the World Health Organization's List of Essential Medicines. Medical uses Albendazole is an effective tr ...
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Hookworm
Hookworms are intestinal, blood-feeding, parasitic roundworms that cause types of infection known as helminthiases. Hookworm infection is found in many parts of the world, and is common in areas with poor access to adequate water, sanitation, and hygiene. In humans, infections are caused by two main species of roundworm, belonging to the genera ''Ancylostoma'' and '' Necator''. In other animals the main parasites are species of ''Ancylostoma''. Species The two most common types of hookworm that infect humans are ''Ancylostoma duodenale'' and ''Necator americanus''. Hookworm species that are known to infect domestic cats are ''Ancylostoma braziliense'' and ''Ancylostoma tubaeforme''. Wild cats are infected by ''Ancylostoma pluridentatum''. Dogs are commonly infected by ''Ancylostoma caninum'', but may also be infected by ''Uncinaria stenocephala'' and ''Ancylostoma braziliense''. In Asia, ''Ancylostoma ceylanicum'' is endemic among dogs and cats and infects humans. Cattle ar ...
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Ascaris Lumbricoides
''Ascaris lumbricoides'' is a large parasitic worm that causes ascariasis in humans. A Nematoda, roundworm of genus ''Ascaris'', it is the most common parasitic worm in humans. An estimated one-sixth of the human population is at some point infected by a roundworm such as ''A. lumbricoides''; people living in tropics, tropical and subtropics, subtropical countries are at greater risk of infection. It has been proposed that ''Ascaris lumbricoides'' and ''Ascaris suum'' (pig roundworm) are the same species. Lifecycle ''Ascaris lumbricoides'', a roundworm, infects humans via the fecal-oral route. Eggs released by adult females are shed in feces. Unfertilized eggs are often observed in fecal samples but never become infective. Fertilized eggs embryonate and become infectious after 18 days to several weeks in soil, depending on the environmental conditions (optimum: moist, warm, shaded soil).Parasites - Ascariasis. (14 February 2018). Retrieved from https://www.cdc.gov/parasites/asc ...
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Entamoeba Histolytica
''Entamoeba histolytica'' is an anaerobic parasitic amoebozoan, part of the genus ''Entamoeba''. Predominantly infecting humans and other primates causing amoebiasis, ''E. histolytica'' is estimated to infect about 35-50 million people worldwide. ''E. histolytica'' infection is estimated to kill more than 55,000 people each year. Previously, it was thought that 10% of the world population was infected, but these figures predate the recognition that at least 90% of these infections were due to a second species, ''E. dispar''. Mammals such as dogs and cats can become infected transiently, but are not thought to contribute significantly to transmission. The word '' histolysis'' literally means disintegration and dissolution of organic tissues. Transmission The active (trophozoite) stage exists only in the host and in fresh loose feces; cysts survive outside the host in water, in soils, and on foods, especially under moist conditions on the latter. The infection can occur when a ...
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Giardia
''Giardia'' ( or ) is a genus of anaerobic flagellated protozoan parasites of the phylum Metamonada that colonise and reproduce in the small intestines of several vertebrates, causing the disease giardiasis. Their life cycle alternates between a swimming trophozoite and an infective, resistant cyst. ''Giardia'' were first described by the Dutch microscopist Antonie van Leeuwenhoek in 1681. The genus is named after French zoologist Alfred Mathieu Giard. Characteristics Like other diplomonads, ''Giardia'' have two nuclei, each with four associated flagella, and were thought to lack both mitochondria and Golgi apparatuses. However, they are now known to possess a complex endomembrane system as well as mitochondrial remnants, called mitosomes, through mitochondrial reduction. The mitosomes are not used in ATP synthesis the way mitochondria are, but are involved in the maturation of iron-sulfur proteins. The synapomorphies of genus ''Giardia'' include cells with duplicate org ...
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Anthelminthics
Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. They may also be called vermifuges (those that stun) or vermicides (those that kill). Anthelmintics are used to treat people who are infected by helminths, a condition called helminthiasis. These drugs are also used to treat infected animals. Pills containing anthelmintics are used in mass deworming campaigns of school-aged children in many developing countries. The drugs of choice for soil-transmitted helminths are mebendazole and albendazole; for schistosomiasis and tapeworms it is praziquantel. Types Antiparasitics that specifically target worms of the genus ''Ascaris'' are called ascaricides. * Benzimidazoles: ** Albendazole – effective against threadworms, roundworms, whipworms, tapeworms, hookworms ** Mebendazole – effective against ...
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Lumen (anatomy)
In biology, a lumen (plural lumina) is the inside space of a tubular structure, such as an artery or intestine. It comes . It can refer to: *The interior of a vessel, such as the central space in an artery, vein or capillary through which blood flows. *The interior of the gastrointestinal tract *The pathways of the bronchi in the lungs *The interior of renal tubules and urinary collecting ducts *The pathways of the female genital tract, starting with a single pathway of the vagina, splitting up in two lumina in the uterus, both of which continue through the Fallopian tubes In cell biology, a lumen is a membrane-defined space that is found inside several organelles, cellular components, or structures: *thylakoid, endoplasmic reticulum, Golgi apparatus, lysosome, mitochondrion, or microtubule Transluminal procedures ''Transluminal procedures'' are procedures occurring through lumina, including: *Natural orifice transluminal endoscopic surgery in the lumina of, for example, the ...
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Open Defecation
Open defecation is the human practice of defecating outdoors ("in the open") rather than into a toilet. People may choose fields, bushes, forests, ditches, streets, canals, or other open spaces for defecation. They do so either because they do not have a toilet readily accessible or due to traditional cultural practices. The practice is common where sanitation infrastructure and services are not available. Even if toilets are available, behavior change efforts may still be needed to promote the use of toilets. 'Open defecation free' (ODF) is a term used to describe communities that have shifted to using toilets instead of open defecation. This can happen, for example, after community-led total sanitation programs have been implemented. Open defecation can pollute the environment and cause health problems and diseases. High levels of open defecation are linked to high child mortality, poor nutrition, poverty, and large disparities between rich and poor. Ending open defecation ...
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