Tracy Palmer
Tracy Palmer is a Professor of Microbiology in the Biosciences Institute at Newcastle University in Tyne & Wear, England. She is known for her work on the twin-arginine translocation (Tat) pathway. Early life and education Palmer was born in Sheffield on 8 May 1967, the only child of Enid (née Wilson) and Roy Palmer (a steelworker). Palmer was brought up in the steel town of Stocksbridge in South Yorkshire where she attended Stocksbridge High School. Palmer attended the University of Birmingham where she was awarded a Bachelor of Science degree in biochemistry in 1988 followed by a PhD in 1992 for research investigating the enzyme kinetics of the proton pumping transhydrogenase from photosynthetic bacteria. She was inspired by the work of Peter D. Mitchell and his work on chemiosmosis during her PhD. Career and research Palmer's main research interest is in the processes by which bacteria secrete proteins into their environment. She was one of the co-discoverers of the ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Royal Society
The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, recognising excellence in science, supporting outstanding science, providing scientific advice for policy, education and public engagement and fostering international and global co-operation. Founded on 28 November 1660, it was granted a royal charter by King Charles II as The Royal Society and is the oldest continuously existing scientific academy in the world. The society is governed by its Council, which is chaired by the Society's President, according to a set of statutes and standing orders. The members of Council and the President are elected from and by its Fellows, the basic members of the society, who are themselves elected by existing Fellows. , there are about 1,700 fellows, allowed to use the postnominal title FRS (Fellow of the ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Stocksbridge High School
Stocksbridge High School is a mixed secondary school for 11 to 16-year-olds, in the town of Stocksbridge, South Yorkshire, England. In December 2017 the school gained Academy school status joining Minerva Learning Trust. History The first school established in Stocksbridge was a small single storey building constructed by a company of Independent Worshippers' on the site of the present NatWest bank in Stocksbridge. The school was named 'Ebeneezer' and was used as both a day school and a chapel. In 1927 Stocksbridge School was constructed on Shay House Lane and Ralph Ellis became the first headmaster. Between 1939 and 1945 the school played an active part in the war effort, and in March 1941 they raised a total of 91 pounds, 17 shillings and 8 pence as part of a 'War Weapons Week.' Two air raid shelters were also constructed, one on the site of the old car park and another on the site of the old sports hall. In 1971 the school became a comprehensive and was renamed to Stocksbr ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Biological Membrane
A biological membrane, biomembrane or cell membrane is a selectively permeable membrane that separates the interior of a cell from the external environment or creates intracellular compartments by serving as a boundary between one part of the cell and another. Biological membranes, in the form of eukaryotic cell membranes, consist of a phospholipid bilayer with embedded, integral and peripheral proteins used in communication and transportation of chemicals and ions. The bulk of lipids in a cell membrane provides a fluid matrix for proteins to rotate and laterally diffuse for physiological functioning. Proteins are adapted to high membrane fluidity environment of the lipid bilayer with the presence of an annular lipid shell, consisting of lipid molecules bound tightly to the surface of integral membrane proteins. The cell membranes are different from the isolating tissues formed by layers of cells, such as mucous membranes, basement membranes, and serous membranes. Composition ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Protein Folding
Protein folding is the physical process by which a protein chain is translated to its native three-dimensional structure, typically a "folded" conformation by which the protein becomes biologically functional. Via an expeditious and reproducible process, a polypeptide folds into its characteristic three-dimensional structure from a random coil. Each protein exists first as an unfolded polypeptide or random coil after being translated from a sequence of mRNA to a linear chain of amino acids. At this stage the polypeptide lacks any stable (long-lasting) three-dimensional structure (the left hand side of the first figure). As the polypeptide chain is being synthesized by a ribosome, the linear chain begins to fold into its three-dimensional structure. Folding of many proteins begins even during translation of the polypeptide chain. Amino acids interact with each other to produce a well-defined three-dimensional structure, the folded protein (the right hand side of the figure), ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Molecular Microbiology (journal)
''Molecular Microbiology'' is a bimonthly peer-reviewed scientific journal covering all aspects of molecular microbiology. It was established in 1987 and is published by Wiley-Blackwell. The editor-in-chief is John D. Helmann (Cornell University). Abstracting and indexing The journal is abstracted and indexed in: According to the ''Journal Citation Reports'', the journal has a 2017 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as i ... of 3.816, ranking it 35th out 125 journals in the category "Microbiology". References External links * {{Official website Publications established in 1987 Microbiology journals Wiley-Blackwell academic journals Biweekly journals English-language journals ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Secretion
440px Secretion is the movement of material from one point to another, such as a secreted chemical substance from a cell or gland. In contrast, excretion is the removal of certain substances or waste products from a cell or organism. The classical mechanism of cell secretion is via secretory portals at the plasma membrane called porosomes. Porosomes are permanent cup-shaped lipoprotein structures embedded in the cell membrane, where secretory vesicles transiently dock and fuse to release intra-vesicular contents from the cell. Secretion in bacterial species means the transport or translocation of effector molecules for example: proteins, enzymes or toxins (such as cholera toxin in pathogenic bacteria e.g. ''Vibrio cholerae'') from across the interior (cytoplasm or cytosol) of a bacterial cell to its exterior. Secretion is a very important mechanism in bacterial functioning and operation in their natural surrounding environment for adaptation and survival. In eukaryotic cells ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Chemiosmosis
Chemiosmosis is the movement of ions across a semipermeable membrane bound structure, down their electrochemical gradient. An important example is the formation of adenosine triphosphate (ATP) by the movement of hydrogen ions (H+) across a membrane during cellular respiration or photosynthesis. Hydrogen ions, or protons, will diffuse from a region of high proton concentration to a region of lower proton concentration, and an electrochemical concentration gradient of protons across a membrane can be harnessed to make ATP. This process is related to osmosis, the movement of water across a selective membrane, which is why it is called "chemiosmosis". ATP synthase is the enzyme that makes ATP by chemiosmosis. It allows protons to pass through the membrane and uses the free energy difference to phosphorylate adenosine diphosphate (ADP), making ATP. The generation of ATP by chemiosmosis occurs in mitochondria and chloroplasts, as well as in most bacteria and archaea. For instan ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Peter D
Peter may refer to: People * List of people named Peter, a list of people and fictional characters with the given name * Peter (given name) ** Saint Peter (died 60s), apostle of Jesus, leader of the early Christian Church * Peter (surname), a surname (including a list of people with the name) Culture * Peter (actor) (born 1952), stage name Shinnosuke Ikehata, Japanese dancer and actor * ''Peter'' (album), a 1993 EP by Canadian band Eric's Trip * ''Peter'' (1934 film), a 1934 film directed by Henry Koster * ''Peter'' (2021 film), Marathi language film * "Peter" (''Fringe'' episode), an episode of the television series ''Fringe'' * ''Peter'' (novel), a 1908 book by Francis Hopkinson Smith * "Peter" (short story), an 1892 short story by Willa Cather Animals * Peter, the Lord's cat, cat at Lord's Cricket Ground in London * Peter (chief mouser), Chief Mouser between 1929 and 1946 * Peter II (cat), Chief Mouser between 1946 and 1947 * Peter III (cat), Chief Mouser between 1947 ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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European Journal Of Biochemistry
''The FEBS Journal'' is a biweekly peer-reviewed scientific journal published by John Wiley & Sons on behalf of the Federation of European Biochemical Societies. It covers research on all aspects of biochemistry, molecular biology, cell biology, and the molecular bases of disease. The editor-in-chief is Seamus Martin (Trinity College Dublin), who took over from Richard Perham (University of Cambridge) in 2014. Content is available for free 1 year after publication, except review content, which is available immediately. The journal also publishes special and virtual issues focusing on a specific theme. Since 2021, the journal has given an annual award, "The FEBS Journal Richard Perham Prize", for an outstanding research paper published in the journal. The winners receive a €5,000 cash prize (to be divided equally between the first and last authors) and the senior author of the study is invited to give a talk at the FEBS Annual Congress. The journal also gives more frequent post ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Photosynthetic
Photosynthesis is a process used by plants and other organisms to convert light energy into chemical energy that, through cellular respiration, can later be released to fuel the organism's activities. Some of this chemical energy is stored in carbohydrate molecules, such as sugars and starches, which are synthesized from carbon dioxide and water – hence the name ''photosynthesis'', from the Greek ''phōs'' (), "light", and ''synthesis'' (), "putting together". Most plants, algae, and cyanobacteria perform photosynthesis; such organisms are called photoautotrophs. Photosynthesis is largely responsible for producing and maintaining the oxygen content of the Earth's atmosphere, and supplies most of the energy necessary for life on Earth. Although photosynthesis is performed differently by different species, the process always begins when energy from light is absorbed by proteins called reaction centers that contain green chlorophyll (and other colored) pigments/chromophores. I ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Transhydrogenase
Transhydrogenase may stand for * NAD(P)+ transhydrogenase (Re/Si-specific) In enzymology, a NAD(P)+ transhydrogenase (''Re''/''Si''-specific () is an enzyme that catalyzes the chemical reaction :NADPH + NAD+ \rightleftharpoons NADP+ + NADH Thus, the two substrates of this enzyme are NADPH and NAD+, whereas its ... * NAD(P)+ transhydrogenase (Si-specific) * Proton-Translocating NAD(P)+ Transhydrogenase * Hydroxyacid-oxoacid transhydrogenase * Glutathione—cystine transhydrogenase * Lactate—malate transhydrogenase * Glutathione—homocystine transhydrogenase * Glutathione—CoA-glutathione transhydrogenase {{enzyme index ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Proton Pump
A proton pump is an integral membrane protein pump that builds up a proton gradient across a biological membrane. Proton pumps catalyze the following reaction: : n one side of a biological membrane/sub> + energy n the other side of the membrane/sub> Mechanisms are based on energy-induced conformational changes of the protein structure or on the Q cycle. During evolution, proton pumps have arisen independently on multiple occasions. Thus, not only throughout nature but also within single cells, different proton pumps that are evolutionarily unrelated can be found. Proton pumps are divided into different major classes of pumps that use different sources of energy, have different polypeptide compositions and evolutionary origins. Function Transport of the positively charged proton is typically electrogenic, i.e. it generates an electric field across the membrane also called the membrane potential. Proton transport becomes electrogenic if not neutralized electrically by transp ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |