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Tonotopic
In physiology, tonotopy (from Greek tono = frequency and topos = place) is the spatial arrangement of where sounds of different frequency are processed in the brain. Tones close to each other in terms of frequency are represented in topologically neighbouring regions in the brain. Tonotopic maps are a particular case of topographic organization, similar to retinotopy in the visual system. Tonotopy in the auditory system begins at the cochlea, the small snail-like structure in the inner ear that sends information about sound to the brain. Different regions of the basilar membrane in the organ of Corti, the sound-sensitive portion of the cochlea, vibrate at different sinusoidal frequencies due to variations in thickness and width along the length of the membrane. Nerves that transmit information from different regions of the basilar membrane therefore encode frequency tonotopically. This tonotopy then projects through the vestibulocochlear nerve and associated midbrain structures ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Auditory Cortex
The auditory cortex is the part of the temporal lobe that processes auditory information in humans and many other vertebrates. It is a part of the auditory system, performing basic and higher functions in hearing, such as possible relations to language switching.Cf. Pickles, James O. (2012). ''An Introduction to the Physiology of Hearing'' (4th ed.). Bingley, UK: Emerald Group Publishing Limited, p. 238. It is located bilaterally, roughly at the upper sides of the temporal lobes – in humans, curving down and onto the medial surface, on the superior temporal plane, within the lateral sulcus and comprising parts of the transverse temporal gyri, and the superior temporal gyrus, including the planum polare and planum temporale (roughly Brodmann areas 41 and 42, and partially 22). The auditory cortex takes part in the spectrotemporal, meaning involving time and frequency, analysis of the inputs passed on from the ear. The cortex then filters and passes on the information to th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Auditory Cortex
The auditory cortex is the part of the temporal lobe that processes auditory information in humans and many other vertebrates. It is a part of the auditory system, performing basic and higher functions in hearing, such as possible relations to language switching.Cf. Pickles, James O. (2012). ''An Introduction to the Physiology of Hearing'' (4th ed.). Bingley, UK: Emerald Group Publishing Limited, p. 238. It is located bilaterally, roughly at the upper sides of the temporal lobes – in humans, curving down and onto the medial surface, on the superior temporal plane, within the lateral sulcus and comprising parts of the transverse temporal gyri, and the superior temporal gyrus, including the planum polare and planum temporale (roughly Brodmann areas 41 and 42, and partially 22). The auditory cortex takes part in the spectrotemporal, meaning involving time and frequency, analysis of the inputs passed on from the ear. The cortex then filters and passes on the information to th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Superior Olivary Complex
The superior olivary complex (SOC) or superior olive is a collection of brainstem nuclei that functions in multiple aspects of hearing and is an important component of the ascending and descending auditory pathways of the auditory system. The SOC is intimately related to the trapezoid body: most of the cell groups of the SOC are dorsal (posterior in primates) to this axon bundle while a number of cell groups are embedded in the trapezoid body. Overall, the SOC displays a significant interspecies variation, being largest in bats and rodents and smaller in primates. Physiology The superior olivary nucleus plays a number of roles in hearing. The medial superior olive (MSO) is a specialized nucleus that is believed to measure the time difference of arrival of sounds between the ears (the interaural time difference or ITD). The ITD is a major cue for determining the azimuth of sounds, i.e., localising them on the azimuthal plane – their degree to the left or the right. The lateral ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Physiology
Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemical and physical functions in a living system. According to the classes of organisms, the field can be divided into medical physiology, animal physiology, plant physiology, cell physiology, and comparative physiology. Central to physiological functioning are biophysical and biochemical processes, homeostatic control mechanisms, and communication between cells. ''Physiological state'' is the condition of normal function. In contrast, ''pathological state'' refers to abnormal conditions, including human diseases. The Nobel Prize in Physiology or Medicine is awarded by the Royal Swedish Academy of Sciences for exceptional scientific achievements in physiology related to the field of medicine. Foundations Cells Although there are differ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sonic Hedgehog
Sonic hedgehog protein (SHH) is encoded for by the ''SHH'' gene. The protein is named after the character ''Sonic the Hedgehog''. This signaling molecule is key in regulating embryonic morphogenesis in all animals. SHH controls organogenesis and the organization of the central nervous system, limbs, digits and many other parts of the body. Sonic hedgehog is a morphogen that patterns the developing embryo using a concentration gradient characterized by the French flag model. This model has a non-uniform distribution of SHH molecules which governs different cell fates according to concentration. Mutations in this gene can cause holoprosencephaly, a failure of splitting in the cerebral hemispheres, as demonstrated in an experiment using SHH knock-out mice in which the forebrain midline failed to develop and instead only a single fused telencephalic vesicle resulted. Sonic hedgehog still plays a role in differentiation, proliferation, and maintenance of adult tissues. Abnormal activ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Place Theory (hearing)
Place theory is a theory of hearing that states that our perception of sound depends on where each component frequency produces vibrations along the basilar membrane. By this theory, the pitch of a sound, such as a human voice or a musical tone, is determined by the places where the membrane vibrates, based on frequencies corresponding to the tonotopic organization of the primary auditory neurons. More generally, schemes that base attributes of auditory perception on the neural firing rate as a function of place are known as rate–place schemes. The main alternative to the place theory is the temporal theory, also known as timing theory. These theories are closely linked with the volley principle or volley theory, a mechanism by which groups of neurons can encode the timing of a sound waveform. In all cases, neural firing patterns in time determine the perception of pitch. The combination known as the place–volley theory uses both mechanisms in combination, primarily coding ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Interaural Time Difference
The interaural time difference (or ITD) when concerning humans or animals, is the difference in arrival time of a sound between two ears. It is important in the localization of sounds, as it provides a cue to the direction or angle of the sound source from the head. If a signal arrives at the head from one side, the signal has further to travel to reach the far ear than the near ear. This pathlength difference results in a time difference between the sound's arrivals at the ears, which is detected and aids the process of identifying the direction of sound source. When a signal is produced in the horizontal plane, its angle in relation to the head is referred to as its azimuth, with 0 degrees (0°) azimuth being directly in front of the listener, 90° to the right, and 180° being directly behind. Different methods for measuring ITDs *For an abrupt stimulus such as a click, onset ITDs are measured. An onset ITD is the time difference between the onset of the signal reaching two ea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Transverse Temporal Gyrus
The transverse temporal gyri, also called Heschl's gyri () or Heschl's convolutions, are gyri found in the area of primary auditory cortex buried within the lateral sulcus of the human brain, occupying Brodmann areas 41 and 42. Transverse temporal gyri are superior to and separated from the planum temporale (cortex involved in language production) by Heschl's sulcus. Transverse temporal gyri are found in varying numbers in both the right and left hemispheres of the brain and one study found that this number is not related to the hemisphere or dominance of hemisphere studied in subjects. Transverse temporal gyri can be viewed in the sagittal plane as either an omega shape (if one gyrus is present) or a heart shape (if two gyri and a sulcus are present). Transverse temporal gyri are the first cortical structures to process incoming auditory information. Anatomically, the transverse temporal gyri are distinct in that they run mediolaterally (toward the center of the brain), rather t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Functional Magnetic Resonance Imaging
Functional magnetic resonance imaging or functional MRI (fMRI) measures brain activity by detecting changes associated with blood flow. This technique relies on the fact that cerebral blood flow and neuronal activation are coupled. When an area of the brain is in use, blood flow to that region also increases. The primary form of fMRI uses the blood-oxygen-level dependent (BOLD) contrast, discovered by Seiji Ogawa in 1990. This is a type of specialized brain and body scan used to map neuron, neural activity in the brain or spinal cord of humans or other animals by imaging the change in blood flow (hemodynamic response) related to energy use by brain cells. Since the early 1990s, fMRI has come to dominate brain mapping research because it does not involve the use of injections, surgery, the ingestion of substances, or exposure to ionizing radiation. This measure is frequently corrupted by noise from various sources; hence, statistical procedures are used to extract the underlying si ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Positron Emission Tomography
Positron emission tomography (PET) is a functional imaging technique that uses radioactive substances known as radiotracers to visualize and measure changes in Metabolism, metabolic processes, and in other physiological activities including blood flow, regional chemical composition, and absorption. Different tracers are used for various imaging purposes, depending on the target process within the body. For example, 18F-FDG, -FDG is commonly used to detect cancer, Sodium fluoride#Medical imaging, NaF is widely used for detecting bone formation, and Isotopes of oxygen#Oxygen-15, oxygen-15 is sometimes used to measure blood flow. PET is a common medical imaging, imaging technique, a Scintigraphy#Process, medical scintillography technique used in nuclear medicine. A radiopharmaceutical, radiopharmaceutical — a radioisotope attached to a drug — is injected into the body as a radioactive tracer, tracer. When the radiopharmaceutical undergoes beta plus decay, a positron is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medial Geniculate Nucleus
The medial geniculate nucleus (MGN) or medial geniculate body (MGB) is part of the auditory thalamus and represents the thalamic relay between the inferior colliculus (IC) and the auditory cortex (AC). It is made up of a number of sub-nuclei that are distinguished by their neuronal morphology and density, by their afferent and efferent connections, and by the coding properties of their neurons. It is thought that the MGN influences the direction and maintenance of attention. Divisions The MGN has three major divisions; ventral (VMGN), dorsal (DMGN) and medial (MMGN). Whilst the VMGN is specific to auditory information processing, the DMGN and MMGN also receive information from non-auditory pathways. Ventral subnucleus Cell types There are two main cell types in the ventral subnucleus of the medial geniculate body (VMGN): * Thalamocortical relay cells (or principal neurons): The dendritic input to these cells comes from two sets of dendritic trees oriented on opposite poles of th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Inferior Colliculus
The inferior colliculus (IC) (Latin for ''lower hill'') is the principal midbrain nucleus of the auditory pathway and receives input from several peripheral brainstem nuclei in the auditory pathway, as well as inputs from the auditory cortex. The inferior colliculus has three subdivisions: the central nucleus, a dorsal cortex by which it is surrounded, and an external cortex which is located laterally. Its bimodal neurons are implicated in auditory-somatosensory interaction, receiving projections from somatosensory nuclei. This multisensory integration may underlie a filtering of self-effected sounds from vocalization, chewing, or respiration activities. The inferior colliculi together with the superior colliculi form the eminences of the corpora quadrigemina, and also part of the tectal region of the midbrain. The inferior colliculus lies caudal to its counterpart – the superior colliculus – above the trochlear nerve, and at the base of the projection of the medial genicu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
_entre_izquierdo_(inferior)_y_correcto_(superior)_orejas.jpg "Click for more on -> Interaural Time Difference")
