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Tom Knight (scientist)
Tom Knight is an American synthetic biologist and computer engineer, who was formerly a senior research scientist at the MIT Computer Science and Artificial Intelligence Laboratory, a part of the MIT School of Engineering. He now works at the synthetic biology company Ginkgo Bioworks, which he cofounded in 2008. Work in electrical engineering and computer science Tom Knight arrived at MIT when he was fourteen. Even though he only started his undergraduate studies at the regular age of 18, he took classes in computer programming and organic chemistry during high school because he lived close to the university. He built early hardware such as ARPANET interfaces for host #6 on the network, some of the first bitmapped displays, the ITS time sharing system, Lisp machines (he was also instrumental in releasing a version of the operating system for the Lisp machine under a BSD license), the Connection Machine, and parallel symbolic processing computer systems. In 1967 Knight ...
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Synthetic Biology
Synthetic biology (SynBio) is a multidisciplinary area of research that seeks to create new biological parts, devices, and systems, or to redesign systems that are already found in nature. It is a branch of science that encompasses a broad range of methodologies from various disciplines, such as biotechnology, biomaterials, material science/engineering, genetic engineering, molecular biology, molecular engineering, systems biology, membrane science, biophysics, chemical and biological engineering, electrical and computer engineering, control engineering and evolutionary biology. Due to more powerful genetic engineering capabilities and decreased DNA synthesis and sequencing costs, the field of synthetic biology is rapidly growing. In 2016, more than 350 companies across 40 countries were actively engaged in synthetic biology applications; all these companies had an estimated net worth of $3.9 billion in the global market. Definition Synthetic biology currently has no gen ...
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Bob Metcalfe
Robert Melancton Metcalfe (born April 7, 1946) is an engineer and entrepreneur from the United States who helped pioneer the Internet starting in 1970. He co-invented Ethernet, co-founded 3Com and formulated Metcalfe's law, which describes the effect of a telecommunications network. Since January 2011, he has been Professor of Innovation and Entrepreneurship at The University of Texas at Austin. He is also the Murchison Fellow of Free Enterprise. Metcalfe has received various awards, including the IEEE Medal of Honor and National Medal of Technology and Innovation for his work developing Ethernet technology. In addition to his accomplishments, Metcalfe has made several predictions which failed to come to pass, separately forecasting the demise of the Internet, wireless networks, and open-source software during the 1990s. Early life Robert Metcalfe was born in 1946 in Brooklyn, New York. His father was a test technician who specialized in gyroscopes. His mother was a homemaker ...
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MIT AI Laboratory
Computer Science and Artificial Intelligence Laboratory (CSAIL) is a research institute at the Massachusetts Institute of Technology (MIT) formed by the 2003 merger of the Laboratory for Computer Science (LCS) and the Artificial Intelligence Laboratory (AI Lab). Housed within the Ray and Maria Stata Center, CSAIL is the largest on-campus laboratory as measured by research scope and membership. It is part of the Schwarzman College of Computing but is also overseen by the MIT Vice President of Research. Research activities CSAIL's research activities are organized around a number of semi-autonomous research groups, each of which is headed by one or more professors or research scientists. These groups are divided up into seven general areas of research: * Artificial intelligence * Computational biology * Graphics and vision * Language and learning * Theory of computation * Robotics * Systems (includes computer architecture, databases, distributed systems, networks and networked sy ...
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Harold J
Harold may refer to: People * Harold (given name), including a list of persons and fictional characters with the name * Harold (surname), surname in the English language * András Arató, known in meme culture as "Hide the Pain Harold" Arts and entertainment * Harold (film), ''Harold'' (film), a 2008 comedy film * ''Harold'', an 1876 poem by Alfred, Lord Tennyson * ''Harold, the Last of the Saxons'', an 1848 book by Edward Bulwer-Lytton, 1st Baron Lytton * ''Harold or the Norman Conquest'', an opera by Frederic Cowen * ''Harold'', an 1885 opera by Eduard Nápravník * Harold, a character from the cartoon List of The Grim Adventures of Billy & Mandy characters#Harold, ''The Grim Adventures of Billy & Mandy'' *Harold & Kumar, a US movie; Harold/Harry is the main actor in the show. Places ;In the United States * Alpine, Los Angeles County, California, an erstwhile settlement that was also known as Harold * Harold, Florida, an unincorporated community * Harold, Kentucky, an ...
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Reversible Computing
Reversible computing is any model of computation where the computational process, to some extent, is time-reversible. In a model of computation that uses deterministic transitions from one state of the abstract machine to another, a necessary condition for reversibility is that the relation of the mapping from states to their successors must be one-to-one. Reversible computing is a form of unconventional computing. Due to the unitarity of quantum mechanics, quantum circuits are reversible, as long as they do not "collapse" the quantum states they operate on. Reversibility There are two major, closely related types of reversibility that are of particular interest for this purpose: physical reversibility and logical reversibility. A process is said to be ''physically reversible'' if it results in no increase in physical entropy; it is isentropic. There is a style of circuit design ideally exhibiting this property that is referred to as charge recovery logic, adiabatic circui ...
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VLSI
Very large-scale integration (VLSI) is the process of creating an integrated circuit (IC) by combining millions or billions of MOS transistors onto a single chip. VLSI began in the 1970s when MOS integrated circuit (Metal Oxide Semiconductor) chips were developed and then widely adopted, enabling complex semiconductor and telecommunication technologies. The microprocessor and memory chips are VLSI devices. Before the introduction of VLSI technology, most ICs had a limited set of functions they could perform. An electronic circuit might consist of a CPU, ROM, RAM and other glue logic. VLSI enables IC designers to add all of these into one chip. History Background The history of the transistor dates to the 1920s when several inventors attempted devices that were intended to control current in solid-state diodes and convert them into triodes. Success came after World War II, when the use of silicon and germanium crystals as radar detectors led to improvements in fabrication ...
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Exa Corporation
Exa Corporation was a developer and distributor of computer-aided engineering (CAE) software. Its main product was PowerFLOW, a lattice-boltzmann derived implementation of computational fluid dynamics (CFD), which can very accurately simulate internal and external flows in low- Mach regimes. PowerFLOW is used extensively in the international automotive and transportation industries. On November 17, 2017, Dassault Systèmes completed acquisition of Exa Corporation. Exa became part of Dassault's SIMULIA brand. History Exa was founded in November, 1991 in Lexington, Massachusetts. Exa raised about $2.4 million in a series of venture capital investments from April 1993 though 1994 from Fidelity Ventures and individuals. More funding was obtained in 1994, 1996, 1998 and 2005, including Boston Capital Ventures as an investor. In 1999, Stephen A. Remondi became chief executive. The company filed for an initial public offering in June 2012. On September 28th, 2017, Dassault Systèmes ...
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Permabit
Permabit Technology Corporation was a private supplier of Data Reduction solutions to the Computer Data Storage industry. On 31 July 2017 it was announced that Red Hat had acquired the assets and technology of Permabit Technology Corporation. Permabit Albireo The Permabit Albireo family of products are designed with data reduction features. The common component among these products is the Albireo index - a hash datastore. Three products in the Albireo family range from an embedded SDK (offering integration with existing storage) to a ready-to-deploy appliance. * Albireo SDK – a software development kit designed to add data deduplication to hardware devices or software applications that benefit from sharing duplicate chunks. * Albireo VDO – a drop-in data efficiency solution for Linux architectures. VDO provides fine-grained (4 KB chunk), inline deduplication, thin provisioning, compression and replication. * Albireo SANblox – a ready-to-run data efficiency appliance that int ...
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Silicon Retina
An event camera, also known as a neuromorphic camera, silicon retina or dynamic vision sensor, is an imaging sensor that responds to local changes in brightness. Event cameras do not capture images using a shutter as conventional (frame) cameras do. Instead, each pixel inside an event camera operates independently and asynchronously, reporting changes in brightness as they occur, and staying silent otherwise. Functional description Event camera pixels independently respond to changes in brightness as they occur. Each pixel stores a reference brightness level, and continuously compares it to the current brightness level. If the difference in brightness exceeds a threshold, that pixel resets its reference level and generates an event: a discrete packet that contains the pixel address and timestamp. Events may also contain the polarity (increase or decrease) of a brightness change, or an instantaneous measurement of the illumination level. Thus, event cameras output an asynchrono ...
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Ethernet
Ethernet () is a family of wired computer networking technologies commonly used in local area networks (LAN), metropolitan area networks (MAN) and wide area networks (WAN). It was commercially introduced in 1980 and first standardized in 1983 as IEEE 802.3. Ethernet has since been refined to support higher bit rates, a greater number of nodes, and longer link distances, but retains much backward compatibility. Over time, Ethernet has largely replaced competing wired LAN technologies such as Token Ring, FDDI and ARCNET. The original 10BASE5 Ethernet uses coaxial cable as a shared medium, while the newer Ethernet variants use twisted pair and fiber optic links in conjunction with switches. Over the course of its history, Ethernet data transfer rates have been increased from the original to the latest , with rates up to under development. The Ethernet standards include several wiring and signaling variants of the OSI physical layer. Systems communicating over Ethernet ...
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Chaosnet
Chaosnet is a local area network technology. It was first developed by Thomas Knight and Jack Holloway at MIT's AI Lab in 1975 and thereafter. It refers to two separate, but closely related, technologies. The more widespread was a set of computer communication packet-based protocols intended to connect the then-recently developed and very popular (within MIT) Lisp machines; the second was one of the earliest local area network (LAN) hardware implementations. Origin The Chaosnet protocol originally used an implementation over CATV coaxial cable modeled on the early Xerox PARC Ethernet, the early ARPANET, and Transmission Control Protocol (TCP). It was a contention-based system intended to work over a range, that included a pseudo-slotted feature intended to reduce collisions, which worked by passing a virtual token of permission from host to host; successful packet transmissions updated each host's knowledge of which host had the token at that time. Collisions caused a host to f ...
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Surface Mount
Surface-mount technology (SMT), originally called planar mounting, is a method in which the electrical components are mounted directly onto the surface of a printed circuit board (PCB). An electrical component mounted in this manner is referred to as a surface-mount device (SMD). In industry, this approach has largely replaced the through-hole technology construction method of fitting components, in large part because SMT allows for increased manufacturing automation which reduces cost and improves quality. It also allows for more components to fit on a given area of substrate. Both technologies can be used on the same board, with the through-hole technology often used for components not suitable for surface mounting such as large transformers and heat-sinked power semiconductors. An SMT component is usually smaller than its through-hole counterpart because it has either smaller leads or no leads at all. It may have short pins or leads of various styles, flat contacts, a matrix ...
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