The Grading Of Recommendations Assessment, Development And Evaluation (GRADE) Approach
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The Grading Of Recommendations Assessment, Development And Evaluation (GRADE) Approach
The GRADE approach (Grading of Recommendations Assessment, Development and Evaluation) is a method of assessing the certainty in evidence (also known as quality of evidence or confidence in effect estimates) and the strength of recommendations in health care. It provides a structured and transparent evaluation of the importance of outcomes of alternative management strategies, acknowledgment of patients and the public values and preferences, and comprehensive criteria for downgrading and upgrading certainty in evidence. It has important implications for those summarizing evidence for systematic reviews, health technology assessments, and clinical practice guidelines as well as other decision makers. However, when used to summarize evidence from nutritional science, dietary, lifestyle and environmental exposure the use of the GRADE approach has been criticized. That is because the GRADE system only allows for randomized controlled trials (RCT) to be rated as high evidence and rates ...
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Systematic Review
A systematic review is a Literature review, scholarly synthesis of the evidence on a clearly presented topic using critical methods to identify, define and assess research on the topic. A systematic review extracts and interprets data from published studies on the topic, then analyzes, describes, and summarizes interpretations into a refined conclusion. For example, a systematic review of randomized controlled trials is a way of summarizing and implementing evidence-based medicine. While a systematic review may be applied in the Biomedical research, biomedical or health care context, it may also be used where an assessment of a precisely defined subject can advance understanding in a field of research. A systematic review may examine clinical tests, public health interventions, environmental interventions, social interventions, adverse effects, qualitative evidence syntheses, methodological reviews, policy reviews, and economic evaluations. An understanding of systematic review ...
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Medical Guideline
Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others. Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of skill and knowledge), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healing, or an ...
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Nutritional Science
Nutritional science (also nutrition science, sometimes short ''nutrition'', dated trophology) is the science that studies the physiological process of nutrition (primarily human nutrition), interpreting the nutrients and other substances in food in relation to maintenance, growth, reproduction, health and disease of an organism. History Before nutritional science emerged as an independent study disciplines, mainly chemists worked in this area. The chemical composition of food was examined. Macronutrients, especially protein, fat and carbohydrates, have been the focus components of the study of (human) nutrition since the 19th century. Until the discovery of vitamins and vital substances, the quality of nutrition was measured exclusively by the intake of nutritional energy. The early years of the 20th century were summarized by Kenneth John Carpenter in his ''Short History of Nutritional Science'' as "the vitamin era". The first vitamin was isolated and chemically defined in 19 ...
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Randomized Controlled Trial
A randomized controlled trial (or randomized control trial; RCT) is a form of scientific experiment used to control factors not under direct experimental control. Examples of RCTs are clinical trials that compare the effects of drugs, surgical techniques, medical devices, diagnostic procedures or other medical treatments. Participants who enroll in RCTs differ from one another in known and unknown ways that can influence study outcomes, and yet cannot be directly controlled. By Random assignment, randomly allocating participants among compared treatments, an RCT enables ''statistical control'' over these influences. Provided it is designed well, conducted properly, and enrolls enough participants, an RCT may achieve sufficient control over these confounding factors to deliver a useful comparison of the treatments studied. Definition and examples An RCT in clinical research typically compares a proposed new treatment against an existing Standard of care#Medical standard of care, ...
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Atherosclerosis
Atherosclerosis is a pattern of the disease arteriosclerosis in which the wall of the artery develops abnormalities, called lesions. These lesions may lead to narrowing due to the buildup of atheroma, atheromatous plaque. At onset there are usually no symptoms, but if they develop, symptoms generally begin around middle age. When severe, it can result in coronary artery disease, stroke, peripheral artery disease, or kidney problems, depending on which Artery, arteries are affected. The exact cause is not known and is proposed to be multifactorial. Risk factors include dyslipidemia, abnormal cholesterol levels, elevated levels of inflammatory markers, high blood pressure, diabetes, smoking, obesity, family history, genetic, and an unhealthy diet. Atheroma, Plaque is made up of fat, cholesterol, calcium, and other substances found in the blood. The narrowing of Artery, arteries limits the flow of oxygen-rich blood to parts of the body. Diagnosis is based upon a physical exam, ele ...
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World Health Organization
The World Health Organization (WHO) is a specialized agency of the United Nations responsible for international public health. The WHO Constitution states its main objective as "the attainment by all peoples of the highest possible level of health". Headquartered in Geneva, Switzerland, it has six regional offices and 150 field offices worldwide. The WHO was established on 7 April 1948. The first meeting of the World Health Assembly (WHA), the agency's governing body, took place on 24 July of that year. The WHO incorporated the assets, personnel, and duties of the League of Nations' Health Organization and the , including the International Classification of Diseases (ICD). Its work began in earnest in 1951 after a significant infusion of financial and technical resources. The WHO's mandate seeks and includes: working worldwide to promote health, keeping the world safe, and serve the vulnerable. It advocates that a billion more people should have: universal health care coverag ...
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National Institute For Health And Care Excellence
The National Institute for Health and Care Excellence (NICE) is an executive non-departmental public body of the Department of Health and Social Care in England that publishes guidelines in four areas: * the use of health technologies within England's National Health Service (NHS) and NHS Wales (such as the use of new and existing medicines, treatments and procedures) * clinical practice (guidance on the appropriate treatment and care of people with specific diseases and conditions) * guidance for public sector workers on health promotion and ill-health avoidance * guidance for social care services and users. These appraisals are based primarily on evidence-based evaluations of efficacy, safety and cost-effectiveness in various circumstances. It serves both the English NHS and the Welsh NHS. It was set up as the National Institute for Clinical Excellence in 1999, and on 1 April 2005 joined with the Health Development Agency to become the new National Institute for Health a ...
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Task Force For Preventive Health Care (Canada)
Task may refer to: * Task (computing), in computing, a program execution context * Task (language instruction) refers to a certain type of activity used in language instruction * Task (project management), an activity that needs to be accomplished within a defined period of time * Task (teaching style) * TASK party, a series of improvisational participatory art-related events organized by artist Oliver Herring * Two-pore-domain potassium channel, a family of potassium ion channels See also * The Task (other) * Task force (other) * Task switching (other) Task switching may refer to: * Context switching in computing * Task switching (psychology) Task switching, or set-shifting, is an executive function that involves the ability to ''unconsciously'' shift attention between one task and another. In ...
* {{disambiguation ...
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Ministry Of Health And Social Protection (Colombia)
The Ministry of Health and Social Protection ( es, Ministerio de Salud y de Protección Social) is one of the sixteen national executive ministries of the Government of Colombia, and is responsible for coordinating and implementing the national policy and social services relating to health and social security. History Upon assuming the Presidency of the Republic in his first term (2002-2006), President Álvaro Uribe Vélez decided to merge the Ministries of Health and Labor into the Ministry of Social Protection. The two ministries that made up the Ministry of Social Protection were the Ministry of Labor, created by Law 96 of 1938, and the Ministry of Health, created under the name of Ministry of Hygiene by Law 27 of 1946 and later called the Ministry of Health. With the passage of Law 1444 of 2011, the Ministry of Social Protection was split into two; according to article 7 of said law, the Ministry of Social Protection was transformed into the Ministry of Labor, and accord ...
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Ministry Of Health (Saudi Arabia)
The Ministry of Health ( ar, وزارة الصحة), commonly abbreviated to MoH, is the ministry overseeing the health care and health policy of Saudi Arabia. The ministry is tasked with formulating strategies to ensure public health in the country, while also managing crucial health infrastructure. The Ministry's origins can be traced by to 1925, when a number of regional health departments were established, with the first in Mecca, Saudi Arabia. As the country grew economically during the 1940s, the Saudi government created the first national Ministry of Health in the country, appointing Abdullah bin Faisal Al Saud as the Kingdom's first Minister of Health. During the next couple of decades, the ministry oversaw the development and construction of numerous hospitals and regional clinics. As the Kingdom of Saudi Arabia economy grew in the 1970s and 1980s, so did its healthcare requirements. During this period the MOH oversaw the construction of hospitals in major cities and oth ...
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