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Taxus Canadensis
''Taxus canadensis'', the Canada yew or Canadian yew, is a conifer native to central and eastern North America, thriving in swampy woods, ravines, riverbanks and on lake shores. Locally called simply "yew", this species is also referred to as American yew or ground-hemlock. Most of its range is well north of the Ohio River. It is, however, found as a rare ice age relict in some coves of the Appalachian Mountains. The southernmost colonies are known from Ashe and Watauga Counties in North Carolina. Description and ecology It is usually a sprawling shrub, rarely exceeding 2.5 m tall. It sometimes forms strong upright central leaders, but these cannot be formed from spreading branches, only from the original leader of the seedling plant. The shrub has thin scaly brown bark. The leaves ( needles) are lanceolate, flat, dark green, long and broad, arranged in two flat rows either side of the branch. The seed cones are highly modified, each cone containing a single seed ...
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Humphry Marshall
Humphry Marshall (October 10, 1722 – November 5, 1801) was an American botanist and plant dealer. Biography Humphry Marshall was born at Derbydown Homestead in the village of Marshallton, Chester County, Pennsylvania, Marshallton, Pennsylvania (within West Bradford Township, Pennsylvania, West Bradford Township) on October 10, 1722. ''Note:'' This includes He was the cousin of botanists John Bartram and William Bartram. Like many early American botanists, he was a Quaker. Marshall received the rudiments of an English education, and was apprenticed to the business of a stonemason, which trade he subsequently followed. Soon after his marriage in 1748 to Sarah Pennock he took charge of his father's farm. His first book, ''A Few Observations Concerning Christ'', in 1755.A Few Observations concerning Christ, or the Eternal Word (London, 1755) https://www.google.com/books/edition/A_Few_Observations_concerning_Christ_or/nhpgAAAAcAAJ?hl=en He began to devote his attention to astron ...
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Waxwing
The waxwings are three species of passerine birds classified in the genus ''Bombycilla''. They are pinkish-brown and pale grey with distinctive smooth plumage in which many body feathers are not individually visible, a black and white eyestripe, a crest, a square-cut tail and pointed wings. Some of the wing feathers have red tips, the resemblance of which to sealing wax gives these birds their common name. According to most authorities, this is the only genus placed in the family Bombycillidae, although sometimes the family is extended to include related taxa that are more usually included in separate families: silky flycatchers (Ptiliogonatidae (e.g. '' Phainoptila'')), ''Hypocolius'' (Hypocoliidae), ''Hylocitrea'' (Hylocitreidae), palmchats (Dulidae) and the Hawai'ian 'honeyeaters' (Mohoidae). There are three species: the Bohemian waxwing (''B. garrulus''), the Japanese waxwing (''B. japonica'') and the cedar waxwing (''B. cedrorum''). Waxwings are not long-distance migrants, ...
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Taxus Brevifolia
''Taxus brevifolia'', the Pacific yew or western yew, is a species of tree in the yew family Taxaceae native to the Pacific Northwest of North America. It is a small evergreen conifer, thriving in moisture and otherwise tending to take the form of a shrub. Description A small evergreen conifer (sometimes appearing as a shrub), the Pacific yew grows to tall and with a trunk up to diameter, rarely more. In some instances, trees with heights in excess of occur in parks and other protected areas, quite often in gullies. The tree is extremely slow growing, and has a habit of rotting from the inside, creating hollow forms. This makes it difficult and sometimes impossible to make accurate ring counts to determine a specimen's true age. Often damaged by succession of the forest, it usually ends up in a squat, multiple-leader form, able to grow new sprouts from decapitated stumps. In its shrub form, sometimes called "yew brush", it can reproduce vegetatively via layering. It has thin ...
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Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. While these symptoms may indicate cancer, they can also have other causes. Over 100 types of cancers affect humans. Tobacco use is the cause of about 22% of cancer deaths. Another 10% are due to obesity, poor diet, lack of physical activity or excessive drinking of alcohol. Other factors include certain infections, exposure to ionizing radiation, and environmental pollutants. In the developing world, 15% of cancers are due to infections such as ''Helicobacter pylori'', hepatitis B, hepatitis C, human papillomavirus infection, Epstein–Barr virus and human immunodeficiency virus (HIV). These factors act, at least partly, by changing the genes of ...
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Taxane
Taxanes are a class of diterpenes. They were originally identified from plants of the genus ''Taxus'' (yews), and feature a taxadiene core. Paclitaxel (Taxol) and docetaxel (Taxotere) are widely used as chemotherapy agents. Cabazitaxel was FDA approved to treat hormone-refractory prostate cancer. Taxanes present difficulties in formulation as medicines because they are poorly soluble in water. Production As their name suggests, taxanes were first derived from natural sources, but some have been semisynthesized. Paclitaxel was originally derived from the Pacific yew tree. Taxanes are difficult to synthesize because of their numerous chiral centres—taxol has 11 of these. Recently, the presence of taxanes in the shells and leaves of ''Corylus avellana'' (the common hazel plant) has been reported. Mechanism of action The principal mechanism of action of the taxane class of drugs is the disruption of microtubule function. Microtubules are essential to cell division, and ta ...
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Atlantic Canada
Atlantic Canada, also called the Atlantic provinces (french: provinces de l'Atlantique), is the region of Eastern Canada comprising the provinces located on the Atlantic coast, excluding Quebec. The four provinces are New Brunswick, Newfoundland and Labrador, Nova Scotia, and Prince Edward Island. As of 2021, the landmass of the four Atlantic provinces was approximately 488,000 km2, and had a population of over 2.4 million people. The provinces combined had an approximate GDP of $121.888 billion in 2011. The term ''Atlantic Canada'' was popularized following the admission of Newfoundland as a Canadian province in 1949. History The first premier of Newfoundland, Joey Smallwood, coined the term "Atlantic Canada" when Newfoundland joined Canada in 1949. He believed that it would have been presumptuous for Newfoundland to assume that it could include itself within the existing term "Maritime provinces," used to describe the cultural similarities shared by New Brunswick, Prince ...
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Québec
Quebec ( ; )According to the Government of Canada, Canadian government, ''Québec'' (with the acute accent) is the official name in Canadian French and ''Quebec'' (without the accent) is the province's official name in Canadian English is one of the thirteen provinces and territories of Canada. It is the List of Canadian provinces and territories by area, largest province by area and the second-largest by Population of Canada by province and territory, population. Much of the population lives in urban areas along the St. Lawrence River, between the most populous city, Montreal, and the provincial capital, Quebec City. Quebec is the home of the Québécois people, Québécois nation. Located in Central Canada, the province shares land borders with Ontario to the west, Newfoundland and Labrador to the northeast, New Brunswick to the southeast, and a coastal border with Nunavut; in the south it borders Maine, New Hampshire, Vermont, and New York (state), New York in the United ...
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Ontario
Ontario ( ; ) is one of the thirteen provinces and territories of Canada.Ontario is located in the geographic eastern half of Canada, but it has historically and politically been considered to be part of Central Canada. Located in Central Canada, it is Canada's most populous province, with 38.3 percent of the country's population, and is the second-largest province by total area (after Quebec). Ontario is Canada's fourth-largest jurisdiction in total area when the territories of the Northwest Territories and Nunavut are included. It is home to the nation's capital city, Ottawa, and the nation's most populous city, Toronto, which is Ontario's provincial capital. Ontario is bordered by the province of Manitoba to the west, Hudson Bay and James Bay to the north, and Quebec to the east and northeast, and to the south by the U.S. states of (from west to east) Minnesota, Michigan, Ohio, Pennsylvania, and New York. Almost all of Ontario's border with the United States f ...
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Herbalism
Herbal medicine (also herbalism) is the study of pharmacognosy and the use of medicinal plants, which are a basis of traditional medicine. With worldwide research into pharmacology, some herbal medicines have been translated into modern remedies, such as the anti-malarial group of drugs called artemisinin isolated from '' Artemisia annua'', a herb that was known in Chinese medicine to treat fever. There is limited scientific evidence for the safety and efficacy of plants used in 21st century herbalism, which generally does not provide standards for purity or dosage. The scope of herbal medicine commonly includes fungal and bee products, as well as minerals, shells and certain animal parts. Herbal medicine is also called phytomedicine or phytotherapy. Paraherbalism describes alternative and pseudoscientific practices of using unrefined plant or animal extracts as unproven medicines or health-promoting agents. Paraherbalism relies on the belief that preserving various ...
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Steambath
A steam bath is a steam-filled room for the purpose of relaxation and cleansing. It has a long history, going back to Greek and Roman times. History The origins of the steam bath come from the Roman bath, which began during the height of the Roman Empire. Ancient Roman baths served many community and social functions within Roman society. Many citizens in Rome used Roman public baths, regardless of socioeconomic status. These Roman baths were supplied by natural hot springs from beneath the ground. Archaeological works at the monastic complex in the Makurian city of Hambukol, has revealed the possible use of one of its rooms as a steam bath. Historical parts of a spa – Roman, medieval, Georgian and Victorian have been restored in Bath, England and is available as a public bath or Thermae. Modern steam baths Today, natural steam baths still exist, and often still use similar systems that the Romans used, which contain pipes and pumps that bring water up and into the large p ...
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Rheumatism
Rheumatism or rheumatic disorders are conditions causing chronic, often intermittent pain affecting the joints or connective tissue. Rheumatism does not designate any specific disorder, but covers at least 200 different conditions, including arthritis and "non-articular rheumatism", also known as "regional pain syndrome" or "soft tissue rheumatism". There is a close overlap between the term soft tissue disorder and rheumatism. Sometimes the term "soft tissue rheumatic disorders" is used to describe these conditions. The term "Rheumatic Diseases" is used in MeSH to refer to connective tissue disorders. The branch of medicine devoted to the diagnosis and therapy of rheumatism is called rheumatology. Types Many rheumatic disorders of chronic, intermittent pain (including joint pain, neck pain or back pain) have historically been caused by infectious diseases. Their etiology was unknown until the 20th century and not treatable. Postinfectious arthritis, also known as reactive art ...
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Toxicity
Toxicity is the degree to which a chemical substance or a particular mixture of substances can damage an organism. Toxicity can refer to the effect on a whole organism, such as an animal, bacterium, or plant, as well as the effect on a substructure of the organism, such as a cell ( cytotoxicity) or an organ such as the liver (hepatotoxicity). By extension, the word may be metaphorically used to describe toxic effects on larger and more complex groups, such as the family unit or society at large. Sometimes the word is more or less synonymous with poisoning in everyday usage. A central concept of toxicology is that the effects of a toxicant are dose-dependent; even water can lead to water intoxication when taken in too high a dose, whereas for even a very toxic substance such as snake venom there is a dose below which there is no detectable toxic effect. Toxicity is species-specific, making cross-species analysis problematic. Newer paradigms and metrics are evolving to bypas ...
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