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Stuart Orkin
Stuart Holland Orkin is an American physician, stem cell biologist and researcher in pediatric hematology-oncology. He is the David G. Nathan Distinguished Professor of Pediatrics at Harvard Medical School. Orkin's research has focused on the genetic basis of blood disorders. He is a member of the National Academy of Sciences and the Institute of Medicine, and an Investigator of the Howard Hughes Medical Institute. Early life Orkin grew up in Manhattan, where his father was a urologist. He studied biology as an undergraduate (B.S., 1967) at the Massachusetts Institute of Technology and earned a medical degree from Harvard Medical School in 1972. He did postdoctoral research in molecular biology at the National Institutes of Health under geneticist Philip Leder. While Orkin was completing his training in hematology-oncology, his department chair, David G. Nathan, allowed him to establish his own research laboratory. Career Orkin is the David G. Nathan Distinguished Professor of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Americans
Americans are the Citizenship of the United States, citizens and United States nationality law, nationals of the United States, United States of America.; ; Although direct citizens and nationals make up the majority of Americans, many Multiple citizenship, dual citizens, expatriates, and green card, permanent residents could also legally claim American nationality. The United States is home to race and ethnicity in the United States, people of many racial and ethnic origins; consequently, culture of the United States, American culture and Law of the United States, law do not equate nationality with Race (human categorization), race or Ethnic group, ethnicity, but with citizenship and an Oath of Allegiance (United States), oath of permanent allegiance. Overview The majority of Americans or their ancestors Immigration to the United States, immigrated to the United States or are descended from people who were Trans Atlantic Slave Trade, brought as Slavery in the United States ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Regulation Of Gene Expression
Regulation of gene expression, or gene regulation, includes a wide range of mechanisms that are used by cells to increase or decrease the production of specific gene products (protein or RNA). Sophisticated programs of gene expression are widely observed in biology, for example to trigger developmental pathways, respond to environmental stimuli, or adapt to new food sources. Virtually any step of gene expression can be modulated, from Transcriptional regulation, transcriptional initiation, to RNA processing, and to the post-translational modification of a protein. Often, one gene regulator controls another, and so on, in a gene regulatory network. Gene regulation is essential for viruses, prokaryotes and eukaryotes as it increases the versatility and adaptability of an organism by allowing the cell to express protein when needed. Although as early as 1951, Barbara McClintock showed interaction between two genetic loci, Activator (''Ac'') and Dissociator (''Ds''), in the color f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kober Medal
The George M. Kober Medal and Lectureship are two different awards by the Association of American Physicians (AAP) in honor of one of its early presidents, George M. Kober. The George M. Kober Lectureship, is an honor given to an AAP member "for outstanding research contributions which have extraordinary impact on patients"; beginning in 1925, the Lectureship has been awarded every three years. The George M. Kober Medal, started in 1927, has, beginning in 1929, been awarded annually (except for 1944 and 1946) to an AAP member "whose lifetime efforts have had an enormous impact ..." Prize winners George M. Kober Lectureship * 1925: John J. Abel, Baltimore * 1928: Simon Flexner, New York * 1931: Frederick George Novy, Ann Arbor * 1934: Walter B. Cannon, Boston * 1937: Ludvig Hektoen, Chicago * 1940: William George MacCallum, Baltimore * 1943: Eugene L. Opie, New York * 1946: Peyton Rous, New York * 1949: Homer F. Swift, New York * 1952: Arthur L. Bloomfield, San Francisco * 195 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Philosophical Society
The American Philosophical Society (APS), founded in 1743 in Philadelphia, is a scholarly organization that promotes knowledge in the sciences and humanities through research, professional meetings, publications, library resources, and community outreach. Considered the first learned society in the United States, it has about 1,000 elected members, and by April 2020 had had only 5,710 members since its creation. Through research grants, published journals, the American Philosophical Society Museum, an extensive library, and regular meetings, the society supports a variety of disciplines in the humanities and the sciences. Philosophical Hall, now a museum, is just east of Independence Hall in Independence National Historical Park; it was designated a National Historic Landmark in 1965. History The Philosophical Society, as it was originally called, was founded in 1743 by Benjamin Franklin, James Alexander (lawyer), James Alexander, Francis Hopkinson, John Bartram, Philip Syn ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
William Allan Award
The William Allan Award, given by the American Society of Human Genetics, was established in 1961 in memory of William Allan (1881–1943), one of the first American physicians to conduct extensive research in human genetics. The William Allan Award is presented annually to recognize substantial and far-reaching scientific contributions to human genetics carried out over a sustained period of scientific inquiry and productivity. An award of $25,000 and an engraved medal are presented at the Annual Meeting. Award recipients Source ASHG See also * List of genetics awards * List of medicine awards This list of medicine awards is an index to articles about notable awards for contributions to medicine, the science and practice of establishing the diagnosis, prognosis, treatment, and prevention of disease. The list is organized by region and ... References {{DEFAULTSORT:Allan Award American science and technology awards Awards established in 1961 Genetics awards Medicine ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Society Of Human Genetics
The American Society of Human Genetics (ASHG), founded in 1948, is a professional membership organization for specialists in human genetics. As of 2009, the organization had approximately 8,000 members. The Society's members include researchers, academicians, clinicians, laboratory practice professionals, genetic counselors, nurses, and others who have a special interest in the field of human genetics. As the field of human genetics has expanded, ASHG has founded additional organizations within its membership body, including the following: * National Society of Genetic Counselors, founded in 1979, as an advocacy group for the nascent field of genetic counseling. * American Board of Medical Genetics, founded in 1981, to certify practitioners in human genetics. * American Board of Genetic Counseling, founded in 1991, to certify genetic counselors. * American College of Medical Genetics, founded in 1991, as a specialty board for medical geneticists at the doctoral level. It achieve ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Society Of Hematology
The American Society of Hematology (ASH) is a professional organization representing hematologists. It was founded in 1958. Its annual meeting is held in December of every year and has attracted more than 30,000 attendees. The society publishes the medical journal ''Blood'', the most cited peer-reviewed publication in the field, and ''Blood Advances'', an online, peer-reviewed open-access journal. The first official ASH meeting was held in Atlantic City, New Jersey, in April 1958. More than 300 hematologists met together to discuss the key research and clinical issues related to blood and blood diseases. Since the first gathering, ASH has been an important member in the development of hematology as a discipline. For more than six decades, ASH has sponsored its annual meeting. Today, ASH has more than 17,000 members, many of whom have made major advancements in understanding and treating blood diseases. Annual meeting Held each year in December, the annual meeting brings together ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Warren Alpert Foundation Prize
The Warren Alpert Foundation Prize is awarded annually to scientist(s) whose scientific achievements have led to the prevention, cure or treatment of human diseases or disorders, and/or whose research constitutes a seminal scientific finding that holds great promise of ultimately changing our understanding of or ability to treat disease. The prize was established in 1987 by the late philanthropist and businessman Warren Alpert and the Warren Alpert Foundation. The Warren Alpert Prize is given internationally and since its inception, 10 winners have gone on to win Nobel Prizes. The prize is administered in concert with Harvard Medical School in Boston, Massachusetts and the Warren Alpert Foundation, located in Providence, Rhode Island. An annual symposium is held at Harvard Medical School each fall where the recipient(s) present their work. The prize currently includes $500,000, a citation and plaque. Warren Alpert Foundation Prize Recipients See also * List of biomedical science ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jessie Stevenson Kovalenko Medal
The Jessie Stevenson Kovalenko Medal is awarded every two years by the US National Academy of Sciences "for important contributions to the medical sciences." It was first awarded in 1952 and involves a prize of $25,000 plus $50,000 for research. The Kovalenko Fund was donated by Michael S. Kovalenko in 1949 to the National Academy of Sciences in memory of his wife, Jessie Stevenson Kovalenko. Recipients See also * List of medicine awards * Prizes named after people A prize is an award to be given to a person or a group of people (such as sporting teams and organizations) to recognize and reward their actions and achievements. References {{National Academy of Sciences, state=collapsed Awards established in 1952[...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Pediatric Society
The American Pediatric Society (APS) is the first pediatric society established in North America. Created in 1888, the APS pursues a vision of an engaged, inclusive, and impactful community of pediatric thought leaders. The APS mission is to shape the future of academic pediatrics through the engagement of distinguished child health leaders. Awards and honors * The John Howland Award, considered the highest honor given by APS, has been awarded since 1952 to honor those who, by their contribution to pediatrics, have aided in its advancement. See also * American Academy of Pediatrics * American College of Pediatricians * Academic Pediatric Association * Society for Pediatric Research A society is a group of individuals involved in persistent social interaction, or a large social group sharing the same spatial or social territory, typically subject to the same political authority and dominant cultural expectations. Socie ... References {{authority control Medical as ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
WBUR-FM
WBUR-FM (90.9 FM) is a public radio station located in Boston, Massachusetts, owned by Boston University. It is the largest of three NPR member stations in Boston, along with WGBH and WUMB-FM and produces several nationally distributed programs, including ''On Point'', '' Here and Now'' and ''Open Source.'' WBUR previously produced ''Car Talk'', '' Only a Game'', and '' The Connection'' (which was cancelled on August 5, 2005). ''RadioBoston'', launched in 2007, is its only purely local show. WBUR's positioning statement is "Boston's NPR News Station". WBUR also carries its programming on two other stations serving Cape Cod and the Islands: WBUH (89.1 FM) in Brewster, and WBUA (92.7 FM) in Tisbury. The latter station, located on Martha's Vineyard, uses the frequency formerly occupied by WMVY."WBUR Buys Mar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sickle-cell Disease
Sickle cell disease (SCD) is a group of blood disorders typically inherited from a person's parents. The most common type is known as sickle cell anaemia. It results in an abnormality in the oxygen-carrying protein haemoglobin found in red blood cells. This leads to a rigid, sickle-like shape under certain circumstances. Problems in sickle cell disease typically begin around 5 to 6 months of age. A number of health problems may develop, such as attacks of pain (known as a sickle cell crisis), anemia, swelling in the hands and feet, bacterial infections and stroke. Long-term pain may develop as people get older. The average life expectancy in the developed world is 40 to 60 years. Sickle cell disease occurs when a person inherits two abnormal copies of the β-globin gene (''HBB'') that makes haemoglobin, one from each parent. This gene occurs in chromosome 11. Several subtypes exist, depending on the exact mutation in each haemoglobin gene. An attack can be set off by temper ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
