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Warren Alpert Foundation Prize
The Warren Alpert Foundation Prize is awarded annually to scientist(s) whose scientific achievements have led to the prevention, cure or treatment of human diseases or disorders, and/or whose research constitutes a seminal scientific finding that holds great promise of ultimately changing our understanding of or ability to treat disease. The prize was established in 1987 by the late philanthropist and businessman Warren Alpert and the Warren Alpert Foundation. The Warren Alpert Prize is given internationally and since its inception, 10 winners have gone on to win Nobel Prizes. The prize is administered in concert with Harvard Medical School in Boston, Massachusetts and the Warren Alpert Foundation, located in Providence, Rhode Island. An annual symposium is held at Harvard Medical School each fall where the recipient(s) present their work. The prize currently includes $500,000, a citation and plaque. Warren Alpert Foundation Prize Recipients See also * List of biomedical science ...
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Warren Alpert
Warren Alpert (December 2, 1920 – March 3, 2007) was an American entrepreneur and philanthropist. Born to poor immigrant parents, he served in U.S. military intelligence during World War II. His privately held businesses distributed gasoline, tobacco and food, and operated a chain of convenience stores and gas stations in the Northeastern United States. He gave away much of his fortune to support medical research at universities and hospitals, donating hundreds of millions of dollars. Early life and education Alpert was born in Chelsea, Massachusetts on December 2, 1920. His parents, Goodman Alpert and Tina Horowitz Alpert, were immigrants from Lithuania, and his father worked as a peddler selling dry goods. He was the youngest of five children. At age 13, Alpert started selling towels and sheets out of the trunk of his father's car. He graduated from Chelsea High School and sold hats after school. He worked seven days a week while earning his bachelor's degree from Boston Univ ...
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Short Bowel Syndrome
Short bowel syndrome (SBS, or simply short gut) is a rare malabsorption disorder caused by a lack of functional small intestine. The primary symptom is diarrhea, which can result in dehydration, malnutrition, and weight loss. Other symptoms may include bloating, heartburn, feeling tired, lactose intolerance, and foul-smelling stool. Complications can include anemia and kidney stones. Most cases are due to the surgical removal of a large portion of the small intestine. This is most often required due to Crohn's disease in adults and necrotising enterocolitis in young children. Other causes include damage to the small intestine from other means and being born with an abnormally short intestine. It usually does not develop until less than of the normally small intestine remains. Treatment may include a specific diet, medications, or surgery. The diet may include slightly salty and slightly sweet liquids, vitamin and mineral supplements, small frequent meals, and the avoidance of ...
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Dana Farber Cancer Institute
Dana may refer to: People Given name * Dana (given name) Surname * Dana (surname) * Dana family of Cambridge, Massachusetts ** James Dwight Dana (1813–1895), scientist, zoological author abbreviation Dana Nickname or stage name * Dana International, stage name of singer Sharon Cohen * Dana Shum, the Shaw Brothers Hong Kong actress from 1973 to 1979 * Dana, stage name of Dana Rosemary Scallon (born 1951), Irish singer and former politician * Dana (South Korean singer) (born 1986), South Korean pop singer Places Ancient world * Ancient Dana or Tyana in Cappadocia, capital of a Neo-Hittite kingdom in the 1st millennium BC * Ancient Dana possibly associated with Tynna in Cappadocia Canada * CFS Dana, a former military radar installation in Saskatchewan, Canada * Dana Lake, a lake in Eeyou Istchee Baie-James, Quebec, Canada Ethiopia * Dana, Ethiopia, a village Iran * Dana County, an administrative subdivision of Iran * Dana Rural District, an administrative subdi ...
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Gordon Freeman (scientist)
Gordon Freeman is the silent protagonist of the ''Half-Life'' video game series, created by Gabe Newell and designed by Newell and Marc Laidlaw of Valve. His first appearance is in ''Half-Life''. Gordon Freeman is depicted as a bespectacled white man from Seattle, with brown hair and a signature goatee, who graduated from MIT with a PhD in theoretical physics. He was an employee at the fictional Black Mesa Research Facility. Controlled by the player, Gordon is often tasked with using a wide range of weapons and tools to fight alien creatures such as headcrabs, as well as Combine machines and soldiers. Gordon Freeman's character has been well received by critics and gamers, and various gaming websites often consider him to be one of the greatest video game characters of all time, including UGO and ''GameSpot''. Character design Valve president and ''Half-Life'' director Gabe Newell coined the name "Gordon Freeman" during a conversation with the game's writer Marc Laidlaw in h ...
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Arlene Sharpe
Arlene Helen Sharpe (born in 1953) is an American immunologist and Kolokotrones University Professor at Harvard University and Chair of the Department of Immunology at Harvard Medical School. In 2017, she received the Warren Alpert Foundation Prize with Gordon Freeman, Lieping Chen, James P. Allison and Tasuku Honjo for their collective contributions to the pre-clinical foundation and development of immune checkpoint blockade, a novel form of cancer therapy that has transformed the landscape of cancer treatment. She served as the hundredth president of the American Association of Immunologists from 2016 to 2017 and served as an AAI Council member from 2013 to 2016. She is the co-director of the Evergrande Center for Immunologic Diseases at Harvard Medical School and Brigham and Women's Hospital. She graduated from Harvard College and Harvard Medical School. Awards and honours * 1993: Beckman Young Investigators Award * 2006: Fellow, American Association for Advancement of Sc ...
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Michael Welsh (academic)
Michael Welsh may refer to: * Michael Welsh (Labour politician) (1926–2012), British Member of Parliament for Doncaster * Michael Welsh (Conservative politician) (born 1942), British former Member of the European Parliament * Michael J. Welsh (biologist), American pulmonologist * Mikey Welsh Michael Edward Welsh (April 20, 1971 – October 8, 2011) was an American artist and musician who played bass for several bands, including the rock band Weezer. During Weezer's hiatus, he played with Weezer frontman Rivers Cuomo in the band Homie ... (1971–2011), American bassist See also * Michael Welch (other) {{hndis, Welsh, Michael ...
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Lap-Chee Tsui
Lap-Chee Tsui (; born 21 December 1950) is a Chinese-born Canadian geneticist and served as the 14th Vice-Chancellor and President of the University of Hong Kong. Personal life Tsui was born in Shanghai. He grew up in Kowloon, Hong Kong and attended Homantin Government Secondary School. He studied Biology at the New Asia College of the Chinese University of Hong Kong and was awarded a B.Sc. (3rd Class Honours) and a M.Phil. in 1972 and 1974, respectively. Upon the recommendation of his mentor at the CUHK, he continued his graduate education in the United States and received his Ph.D. from the University of Pittsburgh in 1979. He became Postdoctoral Investigator and Postdoctoral Fellow in 1979 at Oak Ridge National Laboratory, Tennessee, then joined the Department of Genetics of the Hospital for Sick Children in Toronto in 1981. Career From 1981 to 2002, Tsui continued his research and teaching in the Hospital for Sick Children and the University of Toronto alternatively. Pri ...
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Bonnie Ramsey
Bonnie W. Ramsey is the Endowed Chair in Cystic Fibrosis at the University of Washington School of Medicine and the director of the Center for Clinical and Translational Research at Seattle Children's Research Institute. Her research focuses on treatments for cystic fibrosis. Education Ramsey earned a BA from Stanford University in 1972, and an MD from Harvard Medical School in 1976. She completed a residency at Boston Children's Hospital followed by a fellowship at Seattle Children's Hospital. Career Ramsey joined the faculty at Seattle Children's Hospital in 1979. In 2005, she was named the Endowed Chair in Cystic Fibrosis at the University of Washington School of Medicine. She is also the director of the Center for Clinical and Translational Research at Seattle Children's Research Institute. She was elected as a fellow of the National Academy of Medicine in 2015. She received the Warren Alpert Foundation Prize The Warren Alpert Foundation Prize is awarded annually to sci ...
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Paul Negulescu
Paul Adrian Negulescu is an American-Romanian cell biologist. He is the Senior Vice President and Site Head of the San Diego Research Center of American pharmaceutical company Vertex Pharmaceuticals. He received the 2022 Shaw Prize in Life science and medicine, together with Michael J. Welsh, for their work that uncovered the etiology of cystic fibrosis and developed effective medications. Early life and education Negulescu was born in San Francisco to first-generation immigrants from Romania. His father was a surgeon, and his grandfather, Constantin Vișoianu, was a former Minister of Foreign Affairs of Romania. He has a brother. Thanks to his childhood experience, he initially wanted to graduate with history from the University of California, Berkeley. A third-year physiology class taught by Roger Y. Tsien had a great influence on Negulescu, who eventually graduated with a dual degree in history and physiology in 1986. He then went on and studied PhD in physiology ...
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Francis Collins
Francis Sellers Collins (born April 14, 1950) is an American physician-geneticist who discovered the genes associated with a number of diseases and led the Human Genome Project. He is the former director of the National Institutes of Health (NIH) in Bethesda, Maryland, from 17 August 2009 to 19 December 2021, serving under three presidents, and for over 12 years. Before being appointed director of the NIH, Collins led the Human Genome Project and other genomics research initiatives as director of the National Human Genome Research Institute (NHGRI), one of the 27 institutes and centers at NIH. Before joining NHGRI, he earned a reputation as an LSU Fan at the University of Michigan. He has been elected to the Institute of Medicine and the National Academy of Sciences, and has received the Presidential Medal of Freedom and the National Medal of Science. Collins also has written a number of books on science, medicine, and religion, including the ''New York Times'' bestseller, '' ...
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Optogenetics
Optogenetics is a biological technique to control the activity of neurons or other cell types with light. This is achieved by expression of light-sensitive ion channels, pumps or enzymes specifically in the target cells. On the level of individual cells, light-activated enzymes and transcription factors allow precise control of biochemical signaling pathways. In systems neuroscience, the ability to control the activity of a genetically defined set of neurons has been used to understand their contribution to decision making, learning, fear memory, mating, addiction, feeding, and locomotion. In a first medical application of optogenetic technology, vision was partially restored in a blind patient. Optogenetic techniques have also been introduced to map the functional connectivity of the brain''.'' By altering the activity of genetically labelled neurons with light and using imaging and electrophysiology techniques to record the activity of other cells, researchers can identify ...
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Gero Miesenböck
Gero Andreas Miesenböck (born 15 July 1965) is an Austrian scientist. He is currently Waynflete Professor of Physiology and Director of the Centre for Neural Circuits and Behaviour (CNCB) at the University of Oxford and a fellow of Magdalen College, Oxford. Education and early life A native of Austria, Miesenböck was educated at the University of Innsbruck and Umeå University in Sweden. He graduated sub auspiciis praesidentis rei publicae from the University of Innsbruck Medical School. Following his Doctor of Medicine (MD) in 1993, he undertook postdoctoral training with James Rothman. Research and career Miesenböck is known as the founder of optogenetics. He was the first scientist to modify nerve cells genetically so that their electrical activity could be controlled with light. This involved inserting DNA for light-responsive opsin proteins into the cells. Miesenböck used similar genetic modifications to breed animals whose brains contained light-responsive ne ...
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