Statens Serum Institut
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Statens Serum Institut
Statens Serum Institut (SSI, The State's Serum Institute), is a Danish sector research institute located on the island of Amager in Copenhagen. Its purpose is to combat and prevent infectious diseases, congenital disorders, and threats from weapons of mass destruction. History Founded in 1902 in the barracks of the Artillerivej road, it has now expanded to much more than its original size and is now one of Denmark's largest research institutions in the health sector. 20% of sales are used on Research and Development and Danish and International funds contribute around 100 million DKK. Administratively, the State Serum Institute sorts under the Danish Ministry of Health and Prevention under minister of health. Virologist Herdis von Magnus headed the Institute's enterovirus department in 1955 and led the development and distribution of the polio vaccine in Denmark. The president and CEO of the institute has since 1998 been Niels Strandberg Pedersen. The Department of ...
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Chief Executive Officer
A chief executive officer (CEO), also known as a central executive officer (CEO), chief administrator officer (CAO) or just chief executive (CE), is one of a number of corporate executives charged with the management of an organization especially an independent legal entity such as a company or nonprofit institution. CEOs find roles in a range of organizations, including public and private corporations, non-profit organizations and even some government organizations (notably state-owned enterprises). The CEO of a corporation or company typically reports to the board of directors and is charged with maximizing the value of the business, which may include maximizing the share price, market share, revenues or another element. In the non-profit and government sector, CEOs typically aim at achieving outcomes related to the organization's mission, usually provided by legislation. CEOs are also frequently assigned the role of main manager of the organization and the highest-ranking offic ...
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Doctor Of Medicine
Doctor of Medicine (abbreviated M.D., from the Latin language, Latin ''Medicinae Doctor'') is a medical degree, the meaning of which varies between different jurisdictions. In the United States, and some other countries, the M.D. denotes a professional degree. This generally arose because many in 18th-century medical professions trained in Scotland, which used the M.D. degree nomenclature. In England, however, Bachelor of Medicine, Bachelor of Surgery was used and eventually in the 19th century became the standard in Scotland too. Thus, in the United Kingdom, Republic of Ireland, Ireland and other countries, the M.D. is a research doctorate, honorary degree, honorary doctorate or applied clinical degree restricted to those who already hold a professional degree (Bachelor's/Master's/Doctoral) in medicine. In those countries, the equivalent professional degree to the North American, and some others use of M.D., is still typically titled Bachelor of Medicine, Bachelor of Surgery (M.B ...
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Bandim Health Project
The Bandim Health Project works with population based health research in one of the world's poorest countries, Guinea-Bissau in West Africa. The core of the project is a health and demographic surveillance system which registers more than 100,000 people in six suburbs of the capital Bissau. Furthermore, 182 representative clusters of 100 women and their children are followed in the rural areas. Information on health, diseases, immunisations, breast-feeding, etc. is collected, primarily focusing on women and children. Admissions to the country's sole pediatric ward in the capital are recorded. The Bandim Health Project is member of the INDEPTH Network of health and demographic surveillance sites in Africa, Asia and Oceania. History The Bandim Health Project was initiated in 1978 by Peter Aaby. The project is currently based on collaboration between the Ministry of Public Health in Guinea-Bissau, the Statens Serum Institut in Denmark, and researchers affiliated to The Univer ...
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Guinea-Bissau
Guinea-Bissau ( ; pt, Guiné-Bissau; ff, italic=no, 𞤘𞤭𞤲𞤫 𞤄𞤭𞤧𞤢𞥄𞤱𞤮, Gine-Bisaawo, script=Adlm; Mandinka: ''Gine-Bisawo''), officially the Republic of Guinea-Bissau ( pt, República da Guiné-Bissau, links=no ), is a country in West Africa that covers with an estimated population of 1,726,000. It borders Senegal to the north and Guinea to the south-east. Guinea-Bissau was once part of the kingdom of Kaabu, as well as part of the Mali Empire. Parts of this kingdom persisted until the 18th century, while a few others were under some rule by the Portuguese Empire since the 16th century. In the 19th century, it was colonised as Portuguese Guinea. Portuguese control was restricted and weak until the early 20th century with the pacification campaigns, these campaigns solidified Portuguese sovereignty in the area. The final Portuguese victory over the remaining bastion of mainland resistance, the Papel ruled Kingdom of Bissau in 1915 by the Portu ...
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Poliovirus
A poliovirus, the causative agent of polio (also known as poliomyelitis), is a serotype of the species ''Enterovirus C'', in the family of ''Picornaviridae''. There are three poliovirus serotypes: types 1, 2, and 3. Poliovirus is composed of an RNA genome and a protein capsid. The genome is a single-stranded positive-sense RNA (+ssRNA) genome that is about 7500 nucleotides long. The viral particle is about 30 nm in diameter with icosahedral symmetry. Because of its short genome and its simple composition—only RNA and a nonenveloped icosahedral protein coat that encapsulates it—poliovirus is widely regarded as the simplest significant virus. Poliovirus was first isolated in 1909 by Karl Landsteiner and Erwin Popper. The structure of the virus was first elucidated in 1958 using X-ray diffraction by a team at Birkbeck College led by Rosalind Franklin, showing the polio virus to have icosahedral symmetry. In 1981, the poliovirus genome was published by two different teams ...
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Antibodies
An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein used by the immune system to identify and neutralize foreign objects such as pathogenic bacteria and viruses. The antibody recognizes a unique molecule of the pathogen, called an antigen. Each tip of the "Y" of an antibody contains a paratope (analogous to a lock) that is specific for one particular epitope (analogous to a key) on an antigen, allowing these two structures to bind together with precision. Using this binding mechanism, an antibody can ''tag'' a microbe or an infected cell for attack by other parts of the immune system, or can neutralize it directly (for example, by blocking a part of a virus that is essential for its invasion). To allow the immune system to recognize millions of different antigens, the antigen-binding sites at both tips of the antibody come in an equally wide variety. In contrast, the remainder of the antibody is relatively constant. It only occurs in a few vari ...
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