The Bandim Health Project works with population based health research in one of the world's poorest countries,
Guinea-Bissau
Guinea-Bissau ( ; pt, Guiné-Bissau; ff, italic=no, 𞤘𞤭𞤲𞤫 𞤄𞤭𞤧𞤢𞥄𞤱𞤮, Gine-Bisaawo, script=Adlm; Mandinka: ''Gine-Bisawo''), officially the Republic of Guinea-Bissau ( pt, República da Guiné-Bissau, links=no ) ...
in West Africa.
The core of the project is a health and
demographic surveillance system which registers more than 100,000 people in six suburbs of the capital
Bissau
Bissau () is the capital, and largest city of Guinea-Bissau. Bissau had a population of 492,004. Bissau is located on the Geba River estuary, off the Atlantic Ocean, and is Guinea-Bissau's largest city, major port, and its administrative and m ...
. Furthermore, 182 representative clusters of 100 women and their children are followed in the rural areas. Information on health, diseases, immunisations, breast-feeding, etc. is collected, primarily focusing on women and children. Admissions to the country's sole
pediatric ward in the capital are recorded.
The Bandim Health Project is member of the INDEPTH Network of health and demographic surveillance sites in Africa, Asia and Oceania.
History
The Bandim Health Project was initiated in 1978 by
Peter Aaby. The project is currently based on collaboration between the
Ministry of Public Health in Guinea-Bissau, the
Statens Serum Institut
Statens Serum Institut (SSI, The State's Serum Institute), is a Danish sector research institute located on the island of Amager in Copenhagen. Its purpose is to combat and prevent infectious diseases, congenital disorders, and threats from w ...
in Denmark, and researchers affiliated to The
University of Southern Denmark
The University of Southern Denmark ( da, Syddansk Universitet, lit=South Danish University, abbr. SDU) is a university in Denmark that has campuses located in Southern Denmark and on Zealand.
The university offers a number of joint programmes in ...
, as well as the
University of Aarhus
Aarhus University ( da, Aarhus Universitet, abbreviated AU) is a public research university with its main campus located in Aarhus, Denmark. It is the second largest and second oldest university in Denmark. The university is part of the Coimbra Gr ...
, Denmark.
In 2012, the Danish National Research Foundation funded the establishment of the Center of Excellence, The Research Center for Vitamins and Vaccines (CVIVA) based on the Bandim Health Project and its research into
non-specific effects of vaccines.
Fields of research
The Bandim Health Project works with population based health research, focusing on women and children. The project's fields of research include:
*
Vaccine
A vaccine is a biological Dosage form, preparation that provides active acquired immunity to a particular infectious disease, infectious or cancer, malignant disease. The safety and effectiveness of vaccines has been widely studied and verifie ...
s, both their specific effects on the targeted diseases, and in particular their potential
non-specific effects on
morbidity
A disease is a particular abnormal condition that negatively affects the structure or function of all or part of an organism, and that is not immediately due to any external injury. Diseases are often known to be medical conditions that a ...
and
mortality
Mortality is the state of being mortal, or susceptible to death; the opposite of immortality.
Mortality may also refer to:
* Fish mortality, a parameter used in fisheries population dynamics to account for the loss of fish in a fish stock throug ...
.
* Other
health intervention
A public health intervention is any effort or policy that attempts to improve mental and physical health on a population level. Public health interventions may be run by a variety of organizations, including governmental health departments and n ...
s, including assessment of the total impact on mortality of new interventions or changes in existing policies.
*
Infectious disease
An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable dise ...
s, e.g.
measles
Measles is a highly contagious infectious disease caused by measles virus. Symptoms usually develop 10–12 days after exposure to an infected person and last 7–10 days. Initial symptoms typically include fever, often greater than , cough, ...
,
diarrhoea
Diarrhea, also spelled diarrhoea, is the condition of having at least three loose, liquid, or watery bowel movements each day. It often lasts for a few days and can result in dehydration due to fluid loss. Signs of dehydration often begin wi ...
,
rotavirus
''Rotavirus'' is a genus of double-stranded RNA viruses in the family ''Reoviridae''. Rotaviruses are the most common cause of diarrhoeal disease among infants and young children. Nearly every child in the world is infected with a rotavirus a ...
,
respiratory infection
Respiratory tract infections (RTIs) are infectious diseases involving the respiratory tract. An infection of this type usually is further classified as an upper respiratory tract infection (URI or URTI) or a lower respiratory tract infection (LRI ...
s,
malaria
Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. S ...
, HIV,
HTLV
The human T-lymphotropic virus, human T-cell lymphotropic virus, or human T-cell leukemia-lymphoma virus (HTLV) family of viruses are a group of human retroviruses that are known to cause a type of cancer called adult T-cell leukemia/lymphoma an ...
, and
Tuberculosis
Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in ...
.
* Nutrition, including
micronutrient
Micronutrients are nutrient, essential dietary elements required by organisms in varying quantities throughout life to orchestrate a range of physiological functions to maintain health. Micronutrient requirements differ between organisms; for exam ...
s such as
vitamin A
Vitamin A is a fat-soluble vitamin and an essential nutrient for humans. It is a group of organic compounds that includes retinol, retinal (also known as retinaldehyde), retinoic acid, and several provitamin A carotenoids (most notably bet ...
supplementation, and
breast-feeding
Breastfeeding, or nursing, is the process by which human breast milk is fed to a child. Breast milk may be from the breast, or may be expressed by hand or pumped and fed to the infant. The World Health Organization (WHO) recommends that brea ...
.
*
Humanitarian aid
Humanitarian aid is material and logistic assistance to people who need help. It is usually short-term help until the long-term help by the government and other institutions replaces it. Among the people in need are the homeless, refugees, and ...
.
Important results
One of the most important findings was that a new
measles vaccine
Measles vaccine protects against becoming infected with measles. Nearly all of those who do not develop immunity after a single dose develop it after a second dose. When rate of vaccination within a population is greater than 92%, outbreaks of ...
used in
low-income countries
A developing country is a sovereign state with a lesser developed industrial base and a lower Human Development Index (HDI) relative to other countries. However, this definition is not universally agreed upon. There is also no clear agreem ...
was associated with a two-fold increase in mortality among girls. This discovery led to the withdrawal of the vaccine. Had it not been withdrawn, it could have cost at least ½ million additional female deaths per year in Africa alone.
[Aaby, P. "Being wrong in the right direction?" Lancet 364.9438 (2004): 984.]
The organization
The Bandim Health Project is led by Peter Aaby. The National Research Coordinator is Amabelia Rodrigues. Since the project's foundation in 1978, more than 700
scientific article
: ''For a broader class of literature, see Academic publishing.''
Scientific literature comprises scholarly publications that report original empirical and theoretical work in the natural and social sciences. Within an academic field, scient ...
s have been published, and more than 40 PhD or
doctoral degree
A doctorate (from Latin ''docere'', "to teach"), doctor's degree (from Latin ''doctor'', "teacher"), or doctoral degree is an academic degree awarded by universities and some other educational institutions, derived from the ancient formalism ''li ...
s and 13
Masters of International Health degrees have been obtained by researchers employed by the project.
Affiliations
Bandim Health Project is placed in Guinea-Bissau and also has a small department at
Statens Serum Institut
Statens Serum Institut (SSI, The State's Serum Institute), is a Danish sector research institute located on the island of Amager in Copenhagen. Its purpose is to combat and prevent infectious diseases, congenital disorders, and threats from w ...
in Denmark. Bandim Health Project is also affiliated with
University of Southern Denmark
The University of Southern Denmark ( da, Syddansk Universitet, lit=South Danish University, abbr. SDU) is a university in Denmark that has campuses located in Southern Denmark and on Zealand.
The university offers a number of joint programmes in ...
, where Peter Aaby is an
adjunct professor
An adjunct professor is a type of academic appointment in higher education who does not work at the establishment full-time. The terms of this appointment and
the job security of the tenure vary in different parts of the world, however the genera ...
and Christine Benn holds a professorship in Global Health.
See also
*
Non-specific effect of vaccines
*
Statens Serum Institut
Statens Serum Institut (SSI, The State's Serum Institute), is a Danish sector research institute located on the island of Amager in Copenhagen. Its purpose is to combat and prevent infectious diseases, congenital disorders, and threats from w ...
*
Guinea-Bissau
Guinea-Bissau ( ; pt, Guiné-Bissau; ff, italic=no, 𞤘𞤭𞤲𞤫 𞤄𞤭𞤧𞤢𞥄𞤱𞤮, Gine-Bisaawo, script=Adlm; Mandinka: ''Gine-Bisawo''), officially the Republic of Guinea-Bissau ( pt, República da Guiné-Bissau, links=no ) ...
*
Peter Aaby
References
External links
Official websiteResearch Center for Vitamins and VaccinesStatens Serum Institut
{{authority control
Medical and health organizations based in Denmark
Medical and health organisations based in Guinea-Bissau
Medical research institutes
Public health research