Society Of General Physiologists
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Society Of General Physiologists
The Society of General Physiologists (SGP) is a scientific organization whose purpose is to promote and disseminate knowledge in the field of general physiology, and otherwise to advance understanding and interest in the subject of general physiology. The Society’s main office is located at the Marine Biological Laboratory in Woods Hole, MA, where the society was founded in 1946. Past Presidents of the Society include Richard W. Aldrich, Richard W. Tsien, Clay Armstrong, and Andrew Szent-Gyorgi. The society's archives is held at the National Library of Medicine in Bethesda, Maryland. Membership The Society's international membership is made up of nearly 600 career physiologists who work in academia, government, and industry. Membership in the Society is open to any individual actively interested in the field of general physiology and who has made significant contributions to knowledge in that field. The Society has become known for promoting research in many subfields of cellu ...
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Society Of General Physiologists Logo
A society is a Social group, group of individuals involved in persistent Social relation, social interaction, or a large social group sharing the same spatial or social territory, typically subject to the same Politics, political authority and dominant cultural expectations. Societies are characterized by patterns of relationships (social relations) between individuals who share a distinctive culture and institutions; a given society may be described as the sum total of such relationships among its constituent of members. In the social sciences, a larger society often exhibits social stratification, stratification or dominance hierarchy, dominance patterns in subgroups. Societies construct patterns of behavior by deeming certain actions or concepts as acceptable or unacceptable. These patterns of behavior within a given society are known as societal norms. Societies, and their norms, undergo gradual and perpetual changes. Insofar as it is collaborative, a society can enable i ...
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Physiology
Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemical and physical functions in a living system. According to the classes of organisms, the field can be divided into medical physiology, animal physiology, plant physiology, cell physiology, and comparative physiology. Central to physiological functioning are biophysical and biochemical processes, homeostatic control mechanisms, and communication between cells. ''Physiological state'' is the condition of normal function. In contrast, ''pathological state'' refers to abnormal conditions, including human diseases. The Nobel Prize in Physiology or Medicine is awarded by the Royal Swedish Academy of Sciences for exceptional scientific achievements in physiology related to the field of medicine. Foundations Cells Although there are differ ...
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Marine Biological Laboratory
The Marine Biological Laboratory (MBL) is an international center for research and education in biological and environmental science. Founded in Woods Hole, Massachusetts, in 1888, the MBL is a private, nonprofit institution that was independent for most of its history, but became officially affiliated with the University of Chicago on July 1, 2013. It also collaborates with numerous other institutions. As of 2022, 60 Nobel Prize winners have been affiliated with MBL as students, faculty members or researchers. In addition since 1960, there have been, 137 Howard Hughes Medical Institute investigators, early career scientists, international researchers, and professors; 306 members of the National Academy of Sciences; and 236 Members of the American Academy of Arts and Sciences who have been affiliated with the lab. History 19th century The Marine Biological Laboratory grew from the vision of several Bostonians and Spencer Fullerton Baird, the United States' first Fish Commiss ...
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Woods Hole, MA
Woods Hole is a census-designated place in the town of Falmouth in Barnstable County, Massachusetts, United States. It lies at the extreme southwest corner of Cape Cod, near Martha's Vineyard and the Elizabeth Islands. The population was 781 at the 2010 census. It is the site of several marine science institutions, including Woods Hole Oceanographic Institution, the Marine Biological Laboratory, the Woodwell Climate Research Center, NOAA's Northeast Fisheries Science Center (which started the Woods Hole scientific community in 1871), the Woods Hole Science Aquarium, a USGS coastal and marine geology center, and the home campus of the Sea Education Association. And the headquarter of the Climate Foundation. It is also the site of United States Coast Guard Sector Southeastern New England (formerly USCG Group Woods Hole), the Nobska Light lighthouse, and the terminus of the Steamship Authority ferry route between Cape Cod and the island of Martha's Vineyard. Hist ...
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Richard W
Richard is a male given name. It originates, via Old French, from Old Frankish and is a compound of the words descending from Proto-Germanic ''*rīk-'' 'ruler, leader, king' and ''*hardu-'' 'strong, brave, hardy', and it therefore means 'strong in rule'. Nicknames include "Richie", "Dick", "Dickon", " Dickie", "Rich", "Rick", "Rico", "Ricky", and more. Richard is a common English, German and French male name. It's also used in many more languages, particularly Germanic, such as Norwegian, Danish, Swedish, Icelandic, and Dutch, as well as other languages including Irish, Scottish, Welsh and Finnish. Richard is cognate with variants of the name in other European languages, such as the Swedish "Rickard", the Catalan "Ricard" and the Italian "Riccardo", among others (see comprehensive variant list below). People named Richard Multiple people with the same name * Richard Andersen (other) * Richard Anderson (other) * Richard Cartwright (other) * Ri ...
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Clay Armstrong
Clay Margrave Armstrong (born 1934) is an American physiologist and a former student of Andrew Fielding Huxley. Armstrong received his MD from Washington University School of Medicine in 1960. He is currently emeritus professor of Physiology at the University of Pennsylvania. He has also held professorial appointments at Duke University and the University of Rochester. Armstrong was awarded the Louisa Gross Horwitz Prize from Columbia University in 1996, and the Albert Lasker Award for Basic Medical Research (shared with Bertil Hille and Roderick MacKinnon) in 1999, for his seminal contributions to our understanding of the functions of ion channel proteins in nerve cells. Armstrong was elected to the National Academy of Sciences in 1987, and was elected as a Fellow of the American Academy of Arts and Sciences in 1999. He won the 2001 Gairdner Foundation International Award. Armstrong is married to noted scientist Clara Franzini-Armstrong. Ideas and influence Much of the curren ...
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Membrane Transport
In cellular biology, membrane transport refers to the collection of mechanisms that regulate the passage of solutes such as ions and small molecules through biological membranes, which are lipid bilayers that contain proteins embedded in them. The regulation of passage through the membrane is due to selective membrane permeability - a characteristic of biological membranes which allows them to separate substances of distinct chemical nature. In other words, they can be permeable to certain substances but not to others. The movements of most solutes through the membrane are mediated by membrane transport proteins which are specialized to varying degrees in the transport of specific molecules. As the diversity and physiology of the distinct cells is highly related to their capacities to attract different external elements, it is postulated that there is a group of specific transport proteins for each cell type and for every specific physiological stage /sup>. This differential exp ...
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Ion Channels
Ion channels are pore-forming membrane proteins that allow ions to pass through the channel pore. Their functions include establishing a resting membrane potential, shaping action potentials and other electrical signals by gating the flow of ions across the cell membrane, controlling the flow of ions across secretory and epithelial cells, and regulating cell volume. Ion channels are present in the membranes of all cells. Ion channels are one of the two classes of ionophoric proteins, the other being ion transporters. The study of ion channels often involves biophysics, electrophysiology, and pharmacology, while using techniques including voltage clamp, patch clamp, immunohistochemistry, X-ray crystallography, fluoroscopy, and RT-PCR. Their classification as molecules is referred to as channelomics. Basic features There are two distinctive features of ion channels that differentiate them from other types of ion transporter proteins: #The rate of ion transport through the ...
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Cell Membrane
The cell membrane (also known as the plasma membrane (PM) or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates and protects the interior of all cells from the outside environment (the extracellular space). The cell membrane consists of a lipid bilayer, made up of two layers of phospholipids with cholesterols (a lipid component) interspersed between them, maintaining appropriate membrane fluidity at various temperatures. The membrane also contains membrane proteins, including integral proteins that span the membrane and serve as membrane transporters, and peripheral proteins that loosely attach to the outer (peripheral) side of the cell membrane, acting as enzymes to facilitate interaction with the cell's environment. Glycolipids embedded in the outer lipid layer serve a similar purpose. The cell membrane controls the movement of substances in and out of cells and organelles, being selectively permeable to ions a ...
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Contractility
Contractility refers to the ability for self-contraction, especially of the muscles or similar active biological tissue *Contractile ring in cytokinesis *Contractile vacuole *Muscle contraction **Myocardial contractility *See contractile cell for an overview of cell types in humans. See also *motility Motility is the ability of an organism to move independently, using metabolic energy. Definitions Motility, the ability of an organism to move independently, using metabolic energy, can be contrasted with sessility, the state of organisms th ... {{SIA Cell movement ...
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Molecular Motors
Molecular motors are natural (biological) or artificial molecular machines that are the essential agents of movement in living organisms. In general terms, a motor is a device that consumes energy in one form and converts it into motion or mechanical work; for example, many protein-based molecular motors harness the chemical free energy released by the hydrolysis of ATP in order to perform mechanical work. In terms of energetic efficiency, this type of motor can be superior to currently available man-made motors. One important difference between molecular motors and macroscopic motors is that molecular motors operate in the thermal bath, an environment in which the fluctuations due to thermal noise are significant. Examples Some examples of biologically important molecular motors: * Cytoskeletal motors ** Myosins are responsible for muscle contraction, intracellular cargo transport, and producing cellular tension. ** Kinesin moves cargo inside cells away from the nucleus ...
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The Journal Of General Physiology
''Journal of General Physiology'' is a peer-reviewed scientific journal published by Rockefeller University Press. The journal covers biological, chemical, or physical mechanisms of broad physiological significance. The major emphasis is on physiological problems at the cellular and molecular level. Editorial history The journal was established in 1918 by Jacques Loeb. Editing duties were shared with Winthrop Osterhout of Harvard University. The initial rationale for the journal was stated in this extract from the 1918 announcement of publication: Under the pressure of demands of medicine and other professions, physiology has developed in the direction of an applied science, with limited opportunity for the investigation of purely theoretical problems. On the other hand, the physico-chemical methods of analyzing life phenomena have thus far made little inroad into the domain of zoology and botany. Under these circumstances, it has happened that what might be regarded as the mos ...
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