Sir Alan Fersht
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Sir Alan Fersht
Sir Alan Roy Fersht (born 21 April 1943) is a British chemist at the MRC Laboratory of Molecular Biology, Cambridge, and an Emeritus Professor in the Department of Chemistry at the University of Cambridge. He was Master of Gonville and Caius College, Cambridge from 2012 to 2018. He works on protein folding, and is sometimes described as a founder of protein engineering. Early life and education Fersht was born on 21 April 1943 in Hackney, London. His father, Philip, was a ladies' tailor and his mother, Betty, a dressmaker. His grandparents were Jewish immigrants from Poland, Romania, Lithuania and Belarus. He was educated at Sir George Monoux Grammar School, an all-boys grammar school in Walthamstow, London. He was a keen chess player and was the Essex County Junior champion in 1961. He was awarded a State Scholarship to read Natural Sciences at Gonville and Caius College, Cambridge, where he obtained First Class in Pt I of the Natural Sciences Tripos in 1964, First Class i ...
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Protein Folding
Protein folding is the physical process by which a protein chain is translated to its native three-dimensional structure, typically a "folded" conformation by which the protein becomes biologically functional. Via an expeditious and reproducible process, a polypeptide folds into its characteristic three-dimensional structure from a random coil. Each protein exists first as an unfolded polypeptide or random coil after being translated from a sequence of mRNA to a linear chain of amino acids. At this stage the polypeptide lacks any stable (long-lasting) three-dimensional structure (the left hand side of the first figure). As the polypeptide chain is being synthesized by a ribosome, the linear chain begins to fold into its three-dimensional structure. Folding of many proteins begins even during translation of the polypeptide chain. Amino acids interact with each other to produce a well-defined three-dimensional structure, the folded protein (the right hand side of the figure), ...
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Master (college)
A master (more generically called a head of house or head of college) is the head or senior member of a college within a collegiate university, Colleges within universities in the United Kingdom, principally in the United Kingdom. The actual title of the head of a college varies widely between institutions. The role of master varies significantly between colleges of the same university, and even more so between different universities. However, the master will often have responsibility for leading the governing body of the college, often acting as a chairman, chair of various college committees; for executing the decisions of the governing body through the college's organisational structure, acting as a chief executive officer, chief executive; and for representing the college externally, both within the government of the university and further afield often in aid of fund-raising for the college. The nature of the role varies in importance depending on the nature of the collegia ...
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Royal Society
The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, recognising excellence in science, supporting outstanding science, providing scientific advice for policy, education and public engagement and fostering international and global co-operation. Founded on 28 November 1660, it was granted a royal charter by King Charles II as The Royal Society and is the oldest continuously existing scientific academy in the world. The society is governed by its Council, which is chaired by the Society's President, according to a set of statutes and standing orders. The members of Council and the President are elected from and by its Fellows, the basic members of the society, who are themselves elected by existing Fellows. , there are about 1,700 fellows, allowed to use the postnominal title FRS (Fellow of the ...
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Jesus College, Cambridge
Jesus College is a constituent college of the University of Cambridge. The college's full name is The College of the Blessed Virgin Mary, Saint John the Evangelist and the glorious Virgin Saint Radegund, near Cambridge. Its common name comes from the name of its chapel, Jesus Chapel. Jesus College was established in 1496 on the site of the twelfth-century Benedictine nunnery of St Mary and St Radegund by John Alcock, then Bishop of Ely. The cockerel is the symbol of Jesus College, after the surname of its founder. For the 300 years from 1560 to 1860, Jesus College was primarily a training college for Church of England clergy. Jesus College has assets of approximately £344m making it Cambridge's fourth-wealthiest college. The college is known for its particularly expansive grounds which include its sporting fields and for its close proximity to its boathouse. Three members of Jesus College have received a Nobel Prize. Two fellows of the college have been appointed to the I ...
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Research Fellow
A research fellow is an academic research position at a university or a similar research institution, usually for academic staff or faculty members. A research fellow may act either as an independent investigator or under the supervision of a principal investigator. Although research fellow positions vary in different countries and academic institutions, it is in general that they are junior researchers who try to develop their research careers under the guidance of senior researchers. United Kingdom In many universities this position is a career grade of a ''Research Career Pathway'', following on from a postdoctoral position such as research associate, and may be open-ended, subject to normal probation regulations. Within such a path, the next two higher career grades are usually senior research fellow and professorial fellow. Although similar to the position of a research fellow, these two positions are research only posts, with the rise of the career grade there will normal ...
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William Jencks
William Platt Jencks (August 15, 1927 – January 3, 2007) was an American biochemist. He was noted particularly for his work on enzymes, using concepts drawn from organic chemistry to understand their mechanisms. Career Jencks graduated from Harvard College in 1947 with a degree in English, and earned a Doctor of Medicine from Harvard University in 1951. He interned at the Brigham and Women's Hospital, Peter Bent Brigham hospital. Jencks conducted his first postdoctoral research for two years with Fritz Lipmann at Harvard Medical School. Jencks was drafted into the Army Medical Corps and was assigned to the Army Medical Service Graduate School at Walter Reed Medical Center in Washington, DC. He worked with E. L. Durrum and served as the chair of the department of pharmacology. In 1956–1957, he did a second Public Health Service post-doctoral fellowship, postdoc with R. B. Woodward of the Harvard University Department of Chemistry. In 1957, he moved to the new graduate pr ...
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Brandeis University
, mottoeng = "Truth even unto its innermost parts" , established = , type = Private research university , accreditation = NECHE , president = Ronald D. Liebowitz , provost = Carol Fierke , city = Waltham , state = Massachusetts , country = United States , endowment = $1.07 billion (2019) , students = 5,458 (2021) , undergrad = 3,591 (2021) , postgrad = 1,967 (2021) , faculty = 544 (2021) , administrative_staff = 1,314 (2021) , campus = Small City, , mascot = The Judge and Ollie the Owl (named for Justice Oliver Wendell Holmes Jr.) , sports_nickname = Judges , colors = Brandeis Blue , athletics_affiliations = , academic_affiliations = , website = , logo ...
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State Scholarship (UK)
A State Scholarship was a financial scholarship award for British university entrants based on Scholarship Level exam results. Although the award was based on exam performance, the amount received was means-tested. Most university entrants were funded however by grants from their local education authority. Whilst State Scholarships from the Central Government were greatly sought after for their prestige value they had the same value as local authority grants. In the 1950s, when the pass mark for A-level The A-Level (Advanced Level) is a subject-based qualification conferred as part of the General Certificate of Education, as well as a school leaving qualification offered by the educational bodies in the United Kingdom and the educational aut ... examinations and the more demanding S-level examinations was 40%, the target over three A-levels and two S-levels was about 325/500 for a State Scholarship. Candidates at and above this level were seen by their schools as likely t ...
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Walthamstow
Walthamstow ( or ) is a large town in East London, east London, England, within the Ceremonial counties of England, ceremonial county of Greater London and the Historic counties of England, ancient county of Essex. Situated northeast of Charing Cross, the town borders Chingford to the north, Snaresbrook and South Woodford to the east, Leyton and Leytonstone to the south, and Tottenham to the west. At the 2011 census, the town had a population of approximately 109,424. Occupying most of the town's east-to-west High Street, Walthamstow Market is the longest outdoor market in Europe. East of the town centre is Walthamstow Village, the oldest part of Walthamstow, and the location of St. Mary's Church, Walthamstow, St Mary's Church, the town's parish church. To the north of the town is the former Walthamstow Stadium, which was considered an Cockney, East End landmark. The William Morris Gallery in Forest Road, a museum that was once the family home of William Morris, is a Grade II* ...
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Single-sex Education
Single-sex education, also known as single-gender education and gender-isolated education, is the practice of conducting education with male and female students attending separate classes, perhaps in separate buildings or schools. The practice of single-sex schooling was common before the 20th century, particularly in secondary education, secondary and higher education. Single-sex education is practiced in many parts of the world based on tradition and religion; recently, there has been a surge of interest and the establishment of single-sex schools due to educational research. Single-sex education is most popular in English-speaking countries (regions) such as Singapore, Malaysia, Republic of Ireland, Ireland, the United Kingdom, Hong Kong, South Africa and Australia; also in Chile, Israel, South Korea and in many Muslim majority countries.C. Riordan (2011). The Value of Single Sex Education: Twenty Five Years of High Quality Research, Third International Congress of the European ...
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Sir George Monoux Grammar School
''Sir'' is a formal honorific address in English for men, derived from Sire in the High Middle Ages. Both are derived from the old French "Sieur" (Lord), brought to England by the French-speaking Normans, and which now exist in French only as part of "Monsieur", with the equivalent "My Lord" in English. Traditionally, as governed by law and custom, Sir is used for men titled as knights, often as members of orders of chivalry, as well as later applied to baronets and other offices. As the female equivalent for knighthood is damehood, the female equivalent term is typically Dame. The wife of a knight or baronet tends to be addressed as Lady, although a few exceptions and interchanges of these uses exist. Additionally, since the late modern period, Sir has been used as a respectful way to address a man of superior social status or military rank. Equivalent terms of address for women are Madam (shortened to Ma'am), in addition to social honorifics such as Mrs, Ms or Miss. ...
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Hackney, London
Hackney is a district in East London, England, forming around two-thirds of the area of the modern London Borough of Hackney, to which it gives its name. It is 4 miles (6.4 km) northeast of Charing Cross and includes part of the Queen Elizabeth Olympic Park. Historically it was within the county of Middlesex. In the past it was also referred to as ''Hackney Proper'' to distinguish it from the village which subsequently developed in the vicinity of Mare Street, the term ''Hackney Proper'' being applied to the wider district. Hackney is a large district, whose long established boundaries encompass the sub-districts of Homerton, Dalston (including Kingsland and Shacklewell), De Beauvoir Town, Upper and Lower Clapton, Stamford Hill, Hackney Central, Hackney Wick, South Hackney and West Hackney. Governance Hackney was an administrative unit with consistent boundaries from the early Middle Ages to the creation of the larger modern borough in 1965. It was based for many ce ...
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