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Sid Gilman
Sidney Gilman is a retired physician, neurologist, and educator. He is an expert on Alzheimer's disease and spent the majority of his career at the University of Michigan, its medical school, and its Health System. Early life, family and education Gilman was raised in California. In 1950, he graduated from Huntington Park High School in Huntington Park, California. He graduated from University of California, Los Angeles (UCLA) for his undergraduate degree in 1954 and its medical school in 1957, receiving the highest academic honors. During his college years, he was a gymnastics athlete. He completed his medical residency at Boston City Hospital and a neurology fellowship at Harvard Medical School. He completed a neurophysiology fellowship from 1958 to 1960 at the National Institutes of Health in Bethesda, Maryland. Career Dr. Gilman taught at Harvard Medical School after he completed his research fellowship. He worked at the National Institutes of Health and performed autho ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neurologist
Neurology (from el, νεῦρον (neûron), "string, nerve" and the suffix -logia, "study of") is the branch of medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the brain, the spinal cord and the peripheral nerves. Neurological practice relies heavily on the field of neuroscience, the scientific study of the nervous system. A neurologist is a physician specializing in neurology and trained to investigate, diagnose and treat neurological disorders. Neurologists treat a myriad of neurologic conditions, including stroke, seizures, movement disorders such as Parkinson's disease, autoimmune neurologic disorders such as multiple sclerosis, headache disorders like migraine and dementias such as Alzheimer's disease. Neurologists may also be involved in clinical research, clinical trials, and basic or translational research. While neurology is a nonsurgical specialty, its corresponding surgical specialty is neurosurgery. Histor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Merck Group
The Merck Group, branded and commonly known as Merck, is a German multinational science and technology company headquartered in Darmstadt, with about 60,000 employees and present in 66 countries. The group includes around 250 companies; the main company is Merck KGaA in Germany. The company is divided into three business lines: Healthcare, Life Sciences and Electronics. Merck was founded in 1668 and is the world's oldest operating chemical and pharmaceutical company, as well as one of the largest pharmaceutical companies in the world. Merck operates in Europe, Africa, Asia, Oceania and the Americas. It has major research and development centres in Darmstadt, Boston, Tokyo and Beijing, as well as other Research and Development units in Taiwan, France, Israel, South Korea, India and in the UK. Merck pioneered the commercial manufacture of morphine in the 19th century and for a time held a virtual monopoly on cocaine. Merck was privately owned until going public on the Frankfu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wyeth
Wyeth, LLC was an American pharmaceutical company. The company was founded in Philadelphia, Pennsylvania, in 1860 as ''John Wyeth and Brother''. It was later known, in the early 1930s, as American Home Products, before being renamed to Wyeth in 2002. Its headquarters moved to Collegeville, Pennsylvania and Madison, New Jersey, before they were consolidated with Pfizer's in New York City after the 2009 merger. Most of Wyeth's pharmaceutical assets were acquired by Pfizer in 2009, while its infant and maternal nutrition business was acquired by Nestlé in 2012. Wyeth manufactured over-the-counter drugs (OTCs) Robitussin and the analgesic Advil (ibuprofen) as well as prescription drugs Premarin and Effexor. History 1860–1899 In 1860, pharmacists John (1834–1907) and Frank Wyeth opened a drugstore with a small research lab on Walnut Street in Philadelphia. In 1862, on the suggestion of doctors, they began to manufacture large quantities of commonly ordered medicines ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bapineuzumab
Bapineuzumab (nicknamed "bapi") is a humanized monoclonal antibody that acts on the nervous system and may have potential therapeutic value for the treatment of Alzheimer's disease and possibly glaucoma. However, in 2012 it failed to produce significant cognitive improvements in patients in two major trials, despite lowering key biomarkers of AD, amyloid brain plaque and hyperphosphorylated tau protein in CSF. Bapineuzumab has been shown to recognise the extreme N-terminal 5 residues of Aβ peptide in a helical conformation (4HIX.pdb) stabilized by internal hydrogen bonds involving the first three amino acids. Bapineuzumab is an antibody to the beta-amyloid (Aβ) plaques that are believed to underlie Alzheimer's disease neuropathology. In previous clinical trials for vaccination against human beta amyloid, called AN-1792, patients with Alzheimer's disease using active immunization had positive outcomes with removal of plaques, but 6% of subjects developed aseptic meningitis and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Insider Trading
Insider trading is the trading of a public company's stock or other securities (such as bonds or stock options) based on material, nonpublic information about the company. In various countries, some kinds of trading based on insider information is illegal. This is because it is seen as unfair to other investors who do not have access to the information, as the investor with insider information could potentially make larger profits than a typical investor could make. The rules governing insider trading are complex and vary significantly from country to country. The extent of enforcement also varies from one country to another. The definition of insider in one jurisdiction can be broad, and may cover not only insiders themselves but also any persons related to them, such as brokers, associates, and even family members. A person who becomes aware of non-public information and trades on that basis may be guilty of a crime. Trading by specific insiders, such as employees, is commonl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alzheimer Disease & Associated Disorders
''Alzheimer Disease and Associated Disorders'' is a quarterly peer-reviewed medical journal publishing original research findings and new approaches to diagnosis and treatment for Alzheimer's disease Alzheimer's disease (AD) is a neurodegeneration, neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in short-term me ... and related disorders. Articles published emphasize research in humans including epidemiologic studies, clinical trials and experimental studies, studies of diagnosis and biomarkers, as well as research on health effects of people with dementia. References External links * Quarterly journals Academic journals established in 1987 English-language journals Lippincott Williams & Wilkins academic journals Alzheimer's disease journals {{neurology-journal-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neurobiology Of Disease
''Neurobiology of Disease'' is a monthly peer-reviewed scientific journal covering research on disease mechanisms underlying disorders of the nervous system and behavior. It was established in 1994 and is published by Elsevier. The founding editors-in-chief were Dennis Choi and Jacques Mallet. The current editor-in-chief is T. Greenamyre (University of Pittsburgh). Abstracting and indexing The journal is abstracted and indexed in Scopus, Science Citation Index, Current Contents/Life Sciences, and BIOSIS Previews. According to the ''Journal Citation Reports'', the journal has a 2012 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as i ... of 5.624. References External links * Neuroscience journals Monthly journals Elsevier academic journals Publications esta ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Annals Of Neurology
''Annals of Neurology'' is a peer-reviewed medical journal publishing articles of "broad interest in neurology, particularly those with high impact in understanding the mechanisms and treatment of diseases of the human nervous system." The journal has a 2020 ''Journal Citation Reports'' impact factor of 10.422, ranking it 9th out of 208 journals in the category "Clinical Neurology". History The ''Annals of Neurology'' was launched in 1977. Editors The following people have been editors-in-chief of the journal: * Clifford B. Saper, 2018present * Steven L. Hauser, 2006–2013 * Richard T. Johnson, 1997–2005 * Robert A. Fishman, 1993–1997 * Arthur K. Asbury, 1985–1992 * Fred Plum Fred Plum (January 10, 1924 – June 11, 2010) was an American neurologist who developed the terms "persistent vegetative state" and "locked-in syndrome" as part of his continuing research on consciousness and comas and care of the comatose. ..., 1977–1984 References External links * ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Experimental Neurology
''Experimental Neurology'' is a monthly peer-reviewed medical journal that focuses on research in neuroscience concerning mechanisms underlying neurological disorders. The journal focuses on neural development, neuroregeneration, neuroplasticity, and transplantation,. It was established in 1959 and is published by Elsevier. According to the ''Journal Citation Reports'', the journal has a 2020 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as ... of 5.33. In 1997, ''Experimental Neurology'' absorbed the quarterly journal ''Neurodegeneration'', which had been established in 1992. Past editors-in-chief * 1959–1975: William F. Windle * 1973–1988: Carmine D. Clemente References External links * Elsevier academic journals Monthly journals Neurology journals ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Journal Of Neuropathology And Experimental Neurology
The ''Journal of Neuropathology & Experimental Neurology'' is a monthly peer-reviewed medical journal covering neuropathology and experimental neuroscience. It is published by Oxford University Press and the editor-in-chief is Raymond A. Sobel (Stanford University School of Medicine). It was established in 1942 and is the official journal of the American Association of Neuropathologists. Abstracting and indexing The journal is abstracted and indexed in the Science Citation Index, Current Contents/Life Sciences, BIOSIS Previews, and Index Medicus/MEDLINE/PubMed. According to the ''Journal Citation Reports'', the journal has a 2014 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as i ... of 3.797. Past editors-in-chief * 1942–1949: George B. Hassin * 1950–1952: * 195 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neurology (journal)
''Neurology'' is a weekly peer-reviewed medical journal covering research in neurology. It is published by Wolters Kluwer on behalf of the American Academy of Neurology, of which it is the official journal. It has been edited since April 2020 by José G. Merino (University of Rochester Medical Center, University of Maryland). Previous editors-in-chief The following persons have been editors-in-chief: * Russell N. DeJong (1951-1977; University of Michigan Medical School), founding editor-in-chief * Lewis P. Rowland (1977-1987; Columbia University) * Robert B. Daroff (1987-1997; Case Western Reserve University School of Medicine) * Robert C. Griggs (1997-2007; University of Rochester Medical Center) * John H. Noseworthy (2007-2009; Mayo Clinic) * Robert A. Gross (2009-2020; University of Rochester Medical Center) Abstracting and indexing The journal is abstracted and indexed in: According to the ''Journal Citation Reports'' by Clarivate, the journal has a 2022 impact factor of 11.8 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
