Sid Gilman
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Sidney Gilman is a retired physician,
neurologist Neurology (from el, νεῦρον (neûron), "string, nerve" and the suffix -logia, "study of") is the branch of medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the brain, the spinal c ...
, and educator. He is an expert on Alzheimer's disease and spent the majority of his career at the
University of Michigan , mottoeng = "Arts, Knowledge, Truth" , former_names = Catholepistemiad, or University of Michigania (1817–1821) , budget = $10.3 billion (2021) , endowment = $17 billion (2021)As o ...
, its medical school, and its Health System.


Early life, family and education

Gilman was raised in
California California is a state in the Western United States, located along the Pacific Coast. With nearly 39.2million residents across a total area of approximately , it is the most populous U.S. state and the 3rd largest by area. It is also the m ...
. In 1950, he graduated from
Huntington Park High School Huntington Park High School is a public high school in Huntington Park, California, part of the Los Angeles Unified School District. History The First Grammar School was initially built in 1904. The election was held with 21 registered voters cas ...
in Huntington Park, California. He graduated from
University of California, Los Angeles The University of California, Los Angeles (UCLA) is a public land-grant research university in Los Angeles, California. UCLA's academic roots were established in 1881 as a teachers college then known as the southern branch of the California S ...
(UCLA) for his undergraduate degree in 1954 and its medical school in 1957, receiving the highest academic honors. During his college years, he was a
gymnastics Gymnastics is a type of sport that includes physical exercises requiring balance, strength, flexibility, agility, coordination, dedication and endurance. The movements involved in gymnastics contribute to the development of the arms, legs, s ...
athlete. He completed his medical residency at
Boston City Hospital The Boston City Hospital (1864–1996), in Boston, Massachusetts, was a public hospital, located in the South End. It was "intended for the use and comfort of poor patients, to whom medical care will be provided at the expense of the city, and . ...
and a neurology fellowship at
Harvard Medical School Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consi ...
. He completed a neurophysiology fellowship from 1958 to 1960 at the National Institutes of Health in Bethesda, Maryland.


Career

Dr. Gilman taught at
Harvard Medical School Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consi ...
after he completed his research fellowship. He worked at the
National Institutes of Health The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late ...
and performed authoritative research regarding brain control of motor functions and muscle tone. He began working at
Columbia University Columbia University (also known as Columbia, and officially as Columbia University in the City of New York) is a private research university in New York City. Established in 1754 as King's College on the grounds of Trinity Church in Manhatt ...
in 1968, and in 1976 he was named the first H. Houston Merritt chair in research neurology. In 1977, however, he became professor, chair and chief of service of neurology at the University of Michigan Medical School. The hospital's neurology service named after him, as well as a lecture series. He published hundreds of articles and delivered decades of lectures. His university salary eventually was over US$300,000. His research and areas of interest have involved brain and spinal cord injury, neurological degenerative diseases, and the effects of alcohol on the brain,
R.E.M. R.E.M. was an American rock band from Athens, Georgia, formed in 1980 by drummer Bill Berry, guitarist Peter Buck, bassist Mike Mills, and lead vocalist Michael Stipe, who were students at the University of Georgia. One of the first alternati ...
sleep disorders, Parkinson's disease and Lewy body disease, and cardiac denervation among many other subjects. Some of his research has been in connection with many of the world's largest pharmaceutical companies, including
Merck Merck refers primarily to the German Merck family and three companies founded by the family, including: * the Merck Group, a German chemical, pharmaceutical and life sciences company founded in 1668 ** Merck Serono (known as EMD Serono in the Unite ...
,
Pfizer Pfizer Inc. ( ) is an American multinational pharmaceutical and biotechnology corporation headquartered on 42nd Street in Manhattan, New York City. The company was established in 1849 in New York by two German entrepreneurs, Charles Pfizer ...
, and Johnson & Johnson. In the 2000s, he also worked as a consultant for Wall Street investors including Pequot Capital and Longitude Capital. These jobs increased Gilman's income by more than US$200,000 per year. Gilman has held numerous editorial and advisory board positions with major scientific publications, including ''
Neurology Neurology (from el, νεῦρον (neûron), "string, nerve" and the suffix -logia, "study of") is the branch of medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the brain, the spinal ...
'', '' Journal of Neuropathology and Experimental Neurology'', '' Applied Neurophysiology'', ''
Experimental Neurology ''Experimental Neurology'' is a monthly peer-reviewed medical journal that focuses on research in neuroscience concerning mechanisms underlying neurological disorders. The journal focuses on neural development, neuroregeneration, neuroplasticity ...
'', ''
Annals of Neurology ''Annals of Neurology'' is a peer-reviewed medical journal publishing articles of "broad interest in neurology, particularly those with high impact in understanding the mechanisms and treatment of diseases of the human nervous system." The journal ...
'', '' Neurobiology of Disease'', and '' Alzheimer Disease & Associated Disorders''.


Bapineuzumab controversy

In 2013, Gilman was implicated in the insider trading scandal concerning the Alzheimer's medication bapineuzumab, a drug which was being developed by
Wyeth Wyeth, LLC was an American pharmaceutical company. The company was founded in Philadelphia, Pennsylvania, in 1860 as ''John Wyeth and Brother''. It was later known, in the early 1930s, as American Home Products, before being renamed to Wyeth in ...
and
Élan Elan Corporation plc was a major drugs firm based in Dublin, Ireland, which had major interests in the United States. It was listed on the New York Stock Exchange as ELN, the Irish Stock Exchange as ELN.I, and the London Stock Exchange as ELN. ...
. In exchange for lighter punishment, Gilman agreed to testify and implicate
Mathew Martoma Mathew Martoma (born May 18, 1974, as Ajai Mathew Mariamdani Thomas) is an American former hedge fund trader. As a portfolio manager at S.A.C. Capital Advisors, he was accused of generating possibly the largest single insider trading transaction ...
of CR Intrinsic, a company affiliated with the
hedge fund A hedge fund is a pooled investment fund that trades in relatively liquid assets and is able to make extensive use of more complex trading, portfolio-construction, and risk management techniques in an attempt to improve performance, such as s ...
SAC Capital Advisors. It was considered "the most lucrative insider trading scheme in history." Gilman served no prison time and returned his earnings with interest. As a result, the University of Michigan disassociated itself from him.


Personal life

Gilman and his first wife Linda had two sons, Jeff and Todd. The marriage ended in divorce. Jeff, like his paternal grandmother, committed suicide. In 1984 Sid Gilman married Carol Barbour, a psychoanalyst. After being diagnosed with
lymphoma Lymphoma is a group of blood and lymph tumors that develop from lymphocytes (a type of white blood cell). In current usage the name usually refers to just the cancerous versions rather than all such tumours. Signs and symptoms may include enla ...
, he received
chemotherapy Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs ( chemotherapeutic agents or alkylating agents) as part of a standardized chemotherapy regimen. Chemothe ...
treatment successfully.


Honors and awards

* 1972: Elected Member, The American Society for Clinical Investigation * 1973: Lucy G. Moses Prize in Basic Neurology * 1981: United Cerebral Palsy Weinstein-Goldenson Award for Medical Research for Cerebral Palsy and the Physically Handicapped * 1986–88: President, Michigan Neurological Association * 1988–89: President,
American Neurological Association The American Neurological Association (ANA) is a professional society of academic neurologists and neuroscientists devoted to advancing the goals of academic neurology; to training and educating neurologists and other physicians in the neurologic ...
* 1992: Professional Achievement Award from UCLA Alumni Association * 1995: Elected Member, Institute of Medicine * 1999 Fellow, American Association for the Advancement of Science * 2000 Fellow,
Royal Society of Medicine The Royal Society of Medicine (RSM) is a medical society in the United Kingdom, headquartered in London. History The Society was established in 1805 as Medical and Chirurgical Society of London, meeting in two rooms in barristers’ chamber ...
* 2001 Fellow,
Royal College of Physicians The Royal College of Physicians (RCP) is a British professional membership body dedicated to improving the practice of medicine, chiefly through the accreditation of physicians by examination. Founded by royal charter from King Henry VIII in 1 ...
* 2001 Fellow,
American Academy of Arts and Sciences The American Academy of Arts and Sciences (abbreviation: AAA&S) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, a ...
* 2005: Distinguished University Professorship, University of Michigan Rackham Graduate School * 2010: Medical Center Alumni Society Distinguished Achievement Award, University of Michigan


Publications

*


References


External links


Sid Gilman profile
at University of Michigan Health System (archived)
Curriculum Vitae of Sid Gilman
at annarbor.com American neurologists Alzheimer's disease researchers University of Michigan faculty University of Michigan staff 1932 births Living people Harvard Medical School alumni University of California, Los Angeles alumni Members of the National Academy of Medicine {{US-physician-stub