School Of Life Sciences (University Of Dundee)
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School Of Life Sciences (University Of Dundee)
The School of Life Sciences at the University of Dundee conducts research into the molecular and cellular mechanisms underlying human health and disease. History Life Sciences research at the university began within the Department of Physiology. Following a campaign by Robert P. Cook who was a lecturer in Physiological Chemistry, the Department of Biochemistry was formed in 1965.... In 1970, the University of Dundee appointed Peter Garland CBE as its first Chair of Biochemistry based within the Department. Peter's arrival coincided with the opening of the Medical Sciences Institute (MSI) and Biological Sciences Institute (BSI) that provided up to date facilities for research to take place. The Department of Biochemistry moved from a converted stable block into the MSI alongside the Department of Anatomy and Physiology. In 1971, Peter recruited Sir Philip Cohen to Dundee, where he has remained ever since and who has played an instrumental role in the expansion of life sciences r ...
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University Of Dundee
The University of Dundee; . Abbreviated as ''Dund.'' for post-nominals. is a public university, public research university based in Dundee, Scotland. It was founded as a University college#United Kingdom, university college in 1881 with a donation from the prominent Baxter family of History of Dundee#Industrial revolution, textile manufacturers. The institution was, for most of its early existence, a Collegiate university, constituent college of the University of St Andrews alongside United College, St Andrews, United College and St Mary's College, St Andrews, St Mary's College located in the town of St Andrews itself. Following significant expansion, the University of Dundee gained independent university status by royal charter in 1967 while retaining elements of its ancient university, ancient heritage and ancient university governance in Scotland, governance structure. The main campus of the university is located in Dundee's West End, Dundee, West End, which contains many of the ...
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Peter Downes
Sir Charles Peter Downes (born 15 October 1953), known as Pete Downes, is a British biochemist and chairman of Dynamic Earth in Edinburgh. Downes served as Principal and Vice-Chancellor of the University of Dundee from 2009 until 2018. He is the former Head of the College of Life Sciences and co-founder of the Division of Signal Transduction Therapy (DSTT) alongside Sir Phillip Cohen. Having contributed to research in the pharmaceutical industry for eleven years prior to joining Dundee, he is one of the top 15 most cited bio-scientists in the UK. Career As a pioneering biochemist, Downes was instrumental in establishing the biological importance of the inositol glycerophospholipids and their metabolites. Among his other discoveries are the identification of the mechanism of action for the drug lithium, which has since been used in the treatment of manic depression, and the breakthrough in finding the biochemical pathway that is the most common source of mutations leading to ...
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Biology Education In The United Kingdom
Biology is the scientific study of life. It is a natural science with a broad scope but has several unifying themes that tie it together as a single, coherent field. For instance, all organisms are made up of cells that process hereditary information encoded in genes, which can be transmitted to future generations. Another major theme is evolution, which explains the unity and diversity of life. Energy processing is also important to life as it allows organisms to move, grow, and reproduce. Finally, all organisms are able to regulate their own internal environments. Biologists are able to study life at multiple levels of organization, from the molecular biology of a cell to the anatomy and physiology of plants and animals, and evolution of populations.Based on definition from: Hence, there are multiple subdisciplines within biology, each defined by the nature of their research questions and the tools that they use. Like other scientists, biologists use the scientific metho ...
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Tracy Palmer
Tracy Palmer is a Professor of Microbiology in the Biosciences Institute at Newcastle University in Tyne & Wear, England. She is known for her work on the twin-arginine translocation (Tat) pathway. Early life and education Palmer was born in Sheffield on 8 May 1967, the only child of Enid (née Wilson) and Roy Palmer (a steelworker). Palmer was brought up in the steel town of Stocksbridge in South Yorkshire where she attended Stocksbridge High School. Palmer attended the University of Birmingham where she was awarded a Bachelor of Science degree in biochemistry in 1988 followed by a PhD in 1992 for research investigating the enzyme kinetics of the proton pumping transhydrogenase from photosynthetic bacteria. She was inspired by the work of Peter D. Mitchell and his work on chemiosmosis during her PhD. Career and research Palmer's main research interest is in the processes by which bacteria secrete proteins into their environment. She was one of the co-discoverers of the ...
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Cheryll Tickle
Cheryll Anne Tickle (born 18 January 1945) is a distinguished British scientist, known for her work in developmental biology and specifically for her research into the process by which vertebrate limbs develop '' ab ovo''. She is an Emeritus Professor at the University of Bath. Education Tickle was educated at the University of Cambridge graduating with a Master of Arts degree in 1967, and received her Ph.D. from the University of Glasgow in 1970. Career and research Tickle worked as a postdoctoral researcher at Yale University, as a lecturer and reader at the Middlesex Hospital Medical School, and (after Middlesex merged with it in 1987) a reader and professor at University College London. She then moved to the University of Dundee in 1998, where she became Foulerton Professor of the Royal Society in 2000, and moved again to the University of Bath in 2007, retaining the Foulerton Professor title. Tickle's research in developmental biology investigates how single cells, t ...
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David Lane (oncologist)
Sir David Philip Lane (born 1 July 1952) is a British immunologist, molecular biologist and cancer researcher. He is currently working in the Department of Microbiology, Tumor and Cell Biology at the Karolinska Institute and iChairman of Chugai Pharmabody He is best known for the discovery of p53, one of the most important tumour suppressor genes. Education Lane completed his undergraduate and postgraduate degrees at University College, London where he studied auto-immunity under the supervision of Avrion Mitchison. Career and research Lane carried out postdoctoral research first at the Imperial Cancer Research Fund (ICRF) in London with Lionel Crawford and then at the Cold Spring Harbor Laboratory in New York with Joseph Sambrook. On returning to the UK, Lane set up his own laboratory with Cancer Research Campaign (CRC) funding at Imperial College, London, then moving to the ICRF laboratories at Clare Hall before moving in 1990 to the University of Dundee to help establis ...
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David Glover
David Moore Glover (born 28 March 1948) is a British geneticist and Research Professor of Biology and Biological Engineering at the California Institute of Technology. He served as Balfour Professor of Genetics at the University of Cambridge, a Wellcome Trust investigator in the Department of Genetics at the University of Cambridge, and Fellow of Fitzwilliam College, Cambridge. He serves as the first editor-in-chief of the open-access journal '' Open Biology'' published by the Royal Society. Education Glover was educated at Broadway Technical Grammar School, Barnsley and the University of Cambridge. He undertook his PhD research in the Imperial Cancer Research Fund laboratories as a student of University College London. Career and research As a Damon Runyon Fellow at Stanford University he participated in the Recombinant DNA revolution and discovered sequences that interrupted the ribosomal genes of ''Drosophila''. On establishing his independent laboratory at Imperia ...
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Chris Higgins (academic)
Christopher Francis Higgins (born 24 June 1955) is a British molecular biologist, geneticist, academic and scientific advisor. He was the Vice-Chancellor of Durham University from 2007 to 2014. He took early retirement on 30 September 2014, following a discussion at Senate on limiting the powers of the Vice Chancellor. He was previously the director of the MRC Clinical Sciences Centre and Head of Division in the Faculty of Medicine at Imperial College London. Early life Higgins was born on 24 June 1955 in Cambridge, England. He studied botany at Grey College, Durham University, graduating with a first class degree in 1976. He was awarded a PhD in 1979 for his study of peptide transporters in the embryos of germinating Barley. Working at University of Dundee, his focus turned to genetics and cell biology. Career Higgins was appointed Nuffield Professor of Clinical Biochemistry at the University of Oxford. He has published over 200 papers in leading scientific journals like '' ...
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Athena SWAN
Athena SWAN (Scientific Women's Academic Network) is a quality charter mark framework and accreditation scheme established and managed by the UK Equality Challenge Unit (now part of Advance HE) in 2005 that recognises and celebrates good practices in higher education and research institutions towards the advancement of gender equality: representation, progression and success. History The Athena SWAN charter was established in 2005 and the first awards were conferred in 2006. The initial charter set out to encourage and recognise commitment to advancing the careers of women in science, technology, engineering, mathematics, and medicine (STEMM) institutions of higher education and research. In 2011, the UK Chief Medical Officer made it a requirement for academic departments applying for funding from the English National Institution of Health Research to hold the Athena SWAN silver award. In May 2015 the charter was expanded to include non-STEM departments including arts, human ...
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Visceral Leishmaniasis
Visceral leishmaniasis (VL), also known as kala-azar (Hindi: kālā āzār, "black sickness") or "black fever", is the most severe form of leishmaniasis and, without proper diagnosis and treatment, is associated with high fatality. Leishmaniasis is a disease caused by protozoan parasites of the genus ''Leishmania''. The parasite migrates to the internal organs such as the liver, spleen (hence "visceral"), and bone marrow, and, if left untreated, will almost always result in the death of the host. Signs and symptoms include fever, weight loss, fatigue, anemia, and substantial swelling of the liver and spleen. Of particular concern, according to the World Health Organization (WHO), is the emerging problem of HIV/VL co-infection. VL is the second-largest parasitic killer in the world (after malaria), responsible for an estimated 20,000 to 30,000 deaths each year worldwide. Upendranath Brahmachari synthesised urea stibamine (carbostibamide) in 1922 and determined that it was an ef ...
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Malaria
Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. Symptoms usually begin ten to fifteen days after being bitten by an infected mosquito. If not properly treated, people may have recurrences of the disease months later. In those who have recently survived an infection, reinfection usually causes milder symptoms. This partial resistance disappears over months to years if the person has no continuing exposure to malaria. Malaria is caused by single-celled microorganisms of the ''Plasmodium'' group. It is spread exclusively through bites of infected ''Anopheles'' mosquitoes. The mosquito bite introduces the parasites from the mosquito's saliva into a person's blood. The parasites travel to the liver where they mature and reproduce. Five species of ''Plasmodium'' can infect and be spread by h ...
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Division Of Signal Transduction Therapy
The Division of Signal Transduction Therapy or DSTT is an organization managed by the University of Dundee, the Medical Research Council, and the pharmaceutical companies AstraZeneca, Boehringer Ingelheim, GlaxoSmithKline, Merck Serono, Janssen Pharmaceutica, and Pfizer. The purpose of the collaboration is to conduct cell signalling research and to encourage development of new drug treatments for global diseases such as cancer, rheumatoid arthritis, and Parkinson’s disease. Specifically the collaboration aims to target protein kinases and the ubiquitylation system in the development of these therapies. It is one of the largest ever collaborations between the commercial pharmaceutical industry and any academic research institute. Organizational resources and management The organization was founded by Professor Sir Philip Cohen and Professor Pete Downes in 1998. In 2003 the organization's existence was renewed with £15 million funding, and in 2008 further renewed wit ...
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