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Santosh G. Honavar
Santosh Gajanan Honavar is an Indian ophthalmologist and is currently the editor of the ''Indian Journal of Ophthalmology'' and ''Indian Journal of Ophthalmology - Case Reports'', the official journals of the All India Ophthalmological Society; Director, Medical Services (Centre for Sight Group); Director, Department of Ocular Oncology and Oculoplasty at ''Centre for Sight'', Hyderabad; and Director, National Retinoblastoma Foundation. A former head of the Department of Ophthalmic Plastic Surgery and Ocular Oncology and associate director at L. V. Prasad Eye Institute, he is known for his research on retinoblastoma. He is counted among the top 2% of world researchers and among the top 10 Indian ophthalmologists in research. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, for his contributions t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pune
Pune (; ; also known as Poona, (List of renamed Indian cities and states#Maharashtra, the official name from 1818 until 1978) is one of the most important industrial and educational hubs of India, with an estimated population of 7.4 million As of 2021, Pune Metropolitan Region is the largest in Maharashtra by area, with a geographical area of 7,256 sq km. It has been ranked "the most liveable city in India" several times. Pune is also considered to be the cultural and educational capital of Maharashtra. Along with the municipal corporation area of Pimpri-Chinchwad Municipal Corporation, PCMC, Pune Municipal Corporation, PMC and the three Cantonment Board, cantonment towns of Pune Camp, Camp, Khadki, and Dehu Road, Pune forms the urban core of the eponymous Pune Metropolitan Region (PMR). Situated {{convert, 560, m, 0, abbr=off Height above sea level, above sea level on the Deccan Plateau, Deccan plateau, on the right bank of the Mutha River, Mutha river,{{cite web , last=Nala ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thomas Jefferson University
Thomas Jefferson University is a private research university in Philadelphia, Pennsylvania. Established in its earliest form in 1824, the university officially combined with Philadelphia University in 2017. To signify its heritage, the university sometimes carries the nomenclature ''Jefferson (Philadelphia University + Thomas Jefferson University)'' in its branding. It is classified among "R2: Doctoral Universities – High research activity". The university is named for U.S. Founding Father and president Thomas Jefferson. History Thomas Jefferson University was founded in 1824 and merged with another university located in same city, Philadelphia University, in 2017. Philadelphia University was originally known as Philadelphia Textile School when it was founded in 1884, and then Philadelphia Textile Institute for 20 years (1942 to 1961), Philadelphia College of Textiles & Science for 58 years (1962 to 1999), and Philadelphia University for 18 years (1999 to 2017), its final ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
YouTube
YouTube is a global online video platform, online video sharing and social media, social media platform headquartered in San Bruno, California. It was launched on February 14, 2005, by Steve Chen, Chad Hurley, and Jawed Karim. It is owned by Google, and is the List of most visited websites, second most visited website, after Google Search. YouTube has more than 2.5 billion monthly users who collectively watch more than one billion hours of videos each day. , videos were being uploaded at a rate of more than 500 hours of content per minute. In October 2006, YouTube was bought by Google for $1.65 billion. Google's ownership of YouTube expanded the site's business model, expanding from generating revenue from advertisements alone, to offering paid content such as movies and exclusive content produced by YouTube. It also offers YouTube Premium, a paid subscription option for watching content without ads. YouTube also approved creators to participate in Google's Google AdSens ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pinealoblastoma
Pineoblastoma is a malignant tumor of the pineal gland. A pineoblastoma is a supratentorial midline primitive neuroectodermal tumor. Pineoblastoma can present at any age, but is most common in young children. They account for 0.001% of all primary CNS neoplasms. Epidemiology Pineoblastomas typically occur at very young ages. One study found the average age of presentation to be 4.3 years, with peaks at age 3 and 8. Another cites cases to more commonly occur in patients under 2 years of age. Rates of occurrence for males and females are similar, but may be slightly more common in females. One study found incidence of pineoblastoma to be increased in black patients compared to white patients by around 71%. This difference was most apparent in patients aged 5 to 9 years old. Pathophysiology The pineal gland is a small organ in the center of the brain that is responsible for controlling melatonin secretion. Several tumors can occur in the area of the pineal gland, with the most ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Trilateral Retinoblastoma
Trilateral retinoblastoma is a malignant midline primitive neuroectodermal tumor occurring in patients with inherited uni- or bilateral retinoblastoma. In most cases trilateral retinoblastoma presents itself as pineoblastoma (pineal TRb). In about a fourth of the cases the tumor develops in another intracranial region, most commonly supra- or parasellar (non-pineal TRb), but there are reported cases with non-pineal TRb in the 3rd ventricle. In most cases pineal TRb is diagnosed before the age of 5, but after the diagnosis of retinoblastoma. Non-pineal TRb, however, is often diagnosed simultaneous with retinoblastoma. Prognosis of patients with trilateral retinoblastoma is dismal, only a few patients have survived more than 5 years after diagnosis; all survivors were diagnosed with small tumors in a subclinical stage. Recent advances in (high-dose) chemotherapy treatment regimens and early detection have improved survival of patients with trilateral retinoblastoma. See also * Primi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Coats' Disease
Coats' disease is a rare congenital, nonhereditary eye disorder, causing full or partial blindness, characterized by abnormal development of blood vessels behind the retina. Coats' disease can also fall under glaucoma. It can have a similar presentation to that of retinoblastoma. Signs and symptoms The most common sign at presentation is leukocoria (abnormal white reflection of the retina). Symptoms typically begin as blurred vision, usually pronounced when one eye is closed (due to the unilateral nature of the disease). Often the unaffected eye will compensate for the loss of vision in the other eye; however, this results in some loss of depth perception and parallax. Deterioration of sight may begin in either the central or peripheral vision. Deterioration is likely to begin in the upper part of the vision field as this corresponds with the bottom of the eye where blood usually pools. Flashes of light, known as photopsia, and floaters are common symptoms. Persistent color pa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Retinoblastoma Protein
The retinoblastoma protein (protein name abbreviated pRb; gene name abbreviated ''Rb'', ''RB'' or ''RB1'') is a proto-oncogenic tumor suppressor protein that is dysfunctional in several major cancers. One function of pRb is to prevent excessive cell growth by inhibiting cell cycle progression until a cell is ready to divide. When the cell is ready to divide, pRb is phosphorylated, inactivating it, and the cell cycle is allowed to progress. It is also a recruiter of several chromatin remodeling enzymes such as methylases and acetylases. pRb belongs to the pocket protein family, whose members have a pocket for the functional binding of other proteins. Should an oncogenic protein, such as those produced by cells infected by high-risk types of human papillomavirus, bind and inactivate pRb, this can lead to cancer. The ''RB'' gene may have been responsible for the evolution of multicellularity in several lineages of life including animals. Name and genetics In humans, the prote ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Orbis International
Orbis International is an international non-profit non-governmental organization (NGO) dedicated to saving sight worldwide. Its programs focus on the prevention of blindness and the treatment of blinding eye diseases in developing countries through hands-on training, public health education, advocacy and local partnerships. Since 1982, Orbis capacity-building programs have enhanced the skills of 325,000 eye care personnel and provided medical and optical treatment to more than 23.3 million people in 92 countries. Orbis is a registered 501(c)(3) tax-deductible non-profit charity in the United States. It is rated 4 stars on Charity Navigator and is a Guidestar Gold Participant. It is headquartered in New York, with offices in Toronto, London, Dublin, Hong Kong, Macau, Shanghai, Singapore, Cape Town and Addis Ababa. Orbis' programs emphasise skills, training and self-sufficiency. The organisation spends approximately a year planning and coordinating with partner hospitals and local ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
International Council Of Ophthalmology
The International Council of Ophthalmology (ICO) is an international organisation that represents professional associations of ophthalmologists. It is headquartered in Brussels. The Board of Trustees is the executive body and operational arm of the ICO. History The ICO was established in 1857 in Brussels when 150 ophthalmologists from 24 countries met in the first International Congress of Ophthalmology. The Advisory Board (executive body) was created in 1927 in Scheveningen, Netherlands Member societies were added (International Federation of Ophthalmological Societies) in 1933 in Madrid, Spain. Prior to July 2008, International Federation of Ophthalmological Societies (IFOS) was the official name of the organization, with the ICO serving as the executive body. Over time, "ICO" became better known than IFOS, leading to considerable confusion and a proposal to adopt a single name. The names for the separate parts of the group are now combined under one name, ICO. As a foun ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ResearchGate
ResearchGate is a European commercial social networking site for scientists and researchers to share papers, ask and answer questions, and find collaborators. According to a 2014 study by ''Nature'' and a 2016 article in ''Times Higher Education'', it is the largest academic social network in terms of active users, although other services have more registered users, and a 2015–2016 survey suggests that almost as many academics have Google Scholar profiles. While reading articles does not require registration, people who wish to become site members need to have an email address at a recognized institution or to be manually confirmed as a published researcher in order to sign up for an account. Members of the site each have a user profile and can upload research output including papers, data, chapters, negative results, patents, research proposals, methods, presentations, and software source code. Users may also follow the activities of other users and engage in discussions with th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Google Scholar
Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines. Released in beta in November 2004, the Google Scholar index includes peer-reviewed online academic journals and books, conference papers, theses and dissertations, preprints, abstracts, technical reports, and other scholarly literature, including court opinions and patents. Google Scholar uses a web crawler, or web robot, to identify files for inclusion in the search results. For content to be indexed in Google Scholar, it must meet certain specified criteria. An earlier statistical estimate published in PLOS One using a mark and recapture method estimated approximately 80–90% coverage of all articles published in English with an estimate of 100 million.''Trend Watch'' (2014) Nature 509(7501), 405 – discussing Madian Khabsa and C Lee Giles (2014''The Number of Scholarly Documents on the Public Web'' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brachytherapy
Brachytherapy is a form of radiation therapy where a sealed radiation source is placed inside or next to the area requiring treatment. ''Brachy'' is Greek for short. Brachytherapy is commonly used as an effective treatment for cervical, prostate, breast, esophageal and skin cancer and can also be used to treat tumours in many other body sites. Treatment results have demonstrated that the cancer-cure rates of brachytherapy are either comparable to surgery and external beam radiotherapy (EBRT) or are improved when used in combination with these techniques. Brachytherapy can be used alone or in combination with other therapies such as surgery, EBRT and chemotherapy. Brachytherapy contrasts with unsealed source radiotherapy, in which a therapeutic radionuclide (radioisotope) is injected into the body to chemically localize to the tissue requiring destruction. It also contrasts to External Beam Radiation Therapy (EBRT), in which high-energy x-rays (or occasionally gamma-rays from a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
