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Systems Biomedicine
Systems biomedicine, also called systems biomedical science, is the application of systems biology to the understanding and modulation of developmental and pathological processes in humans, and in animal and cellular models. Whereas systems biology aims at modeling exhaustive networks of interactions (with the long-term goal of, for example, creating a comprehensive computational model of the cell), mainly at intra-cellular level, systems biomedicine emphasizes the multilevel, hierarchical nature of the models (molecule, organelle, cell, tissue, organ, individual/ genotype, environmental factor, population, ecosystem) by discovering and selecting the key factors at each level and integrating them into models that reveal the global, emergent behavior of the biological process under consideration. Such an approach will be favorable when the execution of all the experiments necessary to establish exhaustive models is limited by time and expense (e.g., in animal models) or basic et ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Systems Biology
Systems biology is the computational modeling, computational and mathematical analysis and modeling of complex biological systems. It is a biology-based interdisciplinary field of study that focuses on complex interactions within biological systems, using a holistic approach (holism instead of the more traditional reductionist, reductionism) to biological research. Particularly from the year 2000 onwards, the concept has been used widely in biology in a variety of contexts. The Human Genome Project is an example of applied systems thinking in biology which has led to new, collaborative ways of working on problems in the biological field of genetics. One of the aims of systems biology is to model and discover emergent property, emergent properties, properties of cell (biology), cells, tissue (biology), tissues and organisms functioning as a system whose theoretical description is only possible using techniques of systems biology. These typically involve metabolic networks or cell ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Emergence
In philosophy, systems theory, science, and art, emergence occurs when an entity is observed to have properties its parts do not have on their own, properties or behaviors that emerge only when the parts interact in a wider whole. Emergence plays a central role in theories of integrative levels and of complex systems. For instance, the phenomenon of life as studied in biology is an emergent property of chemistry. In philosophy, theories that emphasize emergent properties have been called emergentism. In philosophy Philosophers often understand emergence as a claim about the etiology of a system's properties. An emergent property of a system, in this context, is one that is not a property of any component of that system, but is still a feature of the system as a whole. Nicolai Hartmann (1882–1950), one of the first modern philosophers to write on emergence, termed this a ''categorial novum'' (new category). Definitions This concept of emergence dates from at least the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Systems Medicine
Systems medicine is an interdisciplinary field of study that looks at the systems of the human body as part of an integrated whole, incorporating biochemical, physiological, and environment interactions. Systems medicine draws on systems science and systems biology, and considers complex interactions within the human body in light of a patient's genomics, behavior and environment. The earliest uses of the term ''systems medicine'' appeared in 1992, in an article on systems medicine and pharmacology by T. Kamada. An important topic in systems medicine and systems biomedicine is the development of computational models that describe disease progression and the effect of therapeutic interventions. More recent approaches include the redefinition of disease phenotypes based on common mechanisms rather than symptoms. These provide then therapeutic targets including network pharmacology and drug repurposing. Since 2018, there is a dedicated scientific journal, ''Systems Medicine''. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Systems Biology
Systems biology is the computational modeling, computational and mathematical analysis and modeling of complex biological systems. It is a biology-based interdisciplinary field of study that focuses on complex interactions within biological systems, using a holistic approach (holism instead of the more traditional reductionist, reductionism) to biological research. Particularly from the year 2000 onwards, the concept has been used widely in biology in a variety of contexts. The Human Genome Project is an example of applied systems thinking in biology which has led to new, collaborative ways of working on problems in the biological field of genetics. One of the aims of systems biology is to model and discover emergent property, emergent properties, properties of cell (biology), cells, tissue (biology), tissues and organisms functioning as a system whose theoretical description is only possible using techniques of systems biology. These typically involve metabolic networks or cell ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Landes Bioscience
Landes Bioscience is an Austin, Texas-based publisher of bioscience journals. ''Cell Cycle'', one of its first two journals, achieved the highest percent increase in total citations in molecular biology and genetics for the period of July–August 2007, with 1490 papers cited 6228 times. It was acquired by Taylor & Francis Taylor & Francis Group is an international company originating in England that publishes books and academic journals. Its parts include Taylor & Francis, Routledge, F1000 (publisher), F1000 Research or Dovepress. It is a division of Informa ... in June 2014. See also * Journals published by Landes Bioscience References External links * {{Authority control Publishing companies of the United States Companies based in Austin, Texas Publishing companies established in 1997 1997 establishments in Texas Academic publishing companies ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oregon Health And Science University
Oregon () is a state in the Pacific Northwest region of the Western United States. The Columbia River delineates much of Oregon's northern boundary with Washington, while the Snake River delineates much of its eastern boundary with Idaho. The 42° north parallel delineates the southern boundary with California and Nevada. Oregon has been home to many indigenous nations for thousands of years. The first European traders, explorers, and settlers began exploring what is now Oregon's Pacific coast in the early-mid 16th century. As early as 1564, the Spanish began sending vessels northeast from the Philippines, riding the Kuroshio Current in a sweeping circular route across the northern part of the Pacific. In 1592, Juan de Fuca undertook detailed mapping and studies of ocean currents in the Pacific Northwest, including the Oregon coast as well as the strait now bearing his name. Spanish ships – 250 in as many years – would typically not land before reaching Cape Mendocino ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Luxembourg
The University of Luxembourg ( French: ''Université du Luxembourg''; German: ''Universität Luxemburg''; Luxembourgish: ''Universitéit Lëtzebuerg'') is a public research university in Luxembourg. History The University of Luxembourg was founded in 2003 by combining four existing education and research institutes: the Centre universitaire, Institut supérieur d'études et de recherches pédagogiques, Institut supérieur de technologie, and Institut d'études éducatives et sociales. The university is the only public university in Luxembourg. Description The university has three campuses: the Belval Campus, the Kirchberg Campus, and the Limpertsberg Campus. The university is governed by a board of governors, a rector, and a university council. The current rector of the University of Luxembourg is Stéphane Pallage. Academics The university offers fourteen bachelor's degrees, forty-two master's degrees, and doctorates. Bachelor's degrees require a semester abroad. The u ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rudi Balling
Rudi Balling (born 17 October 1953 in Daun, Germany, Daun, Rhineland-Palatinate) is a German geneticist. He is the founding director of the Luxembourg Centre for Systems Biomedicine at the University of Luxembourg (2009-2021) He has served as President of the International Mammalian Genome Society (IMGS, 2001–2002) and as co-editor-in-chief, editor of the ''Annual Review of Nutrition'' since 2018. In 2016 Balling received Luxembourg's Ordre de Mérite (Commandeur) from Prime Minister Xavier Bettel. Biography Following his abitur (1972) at the Geschwister-Scholl Gymnasium (school), Gymnasium in Daun, Germany and military service, Rudi Balling studied nutritional science at the University of Bonn, Germany from 1974 - 1981. He held a Fulbright scholarship from 1978 - 1979 at Washington State University in Pullman, Washington, USA where he studied animal nutrition. Balling received a master's degree from Washington State in 1980 and a Diploma in Human Nutrition from the Universi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
European Institute Of Oncology
The European Institute of Oncology ( it, Istituto Europeo di Oncologia, IEO) is a non-profit private-law comprehensive cancer centre located in Milan, Italy. It is a clinic, a research centre and a training institution. IEO is a member of EU-LIFE, an alliance of leading life science research centres in Europe. The European Institute of Oncology works on the prevention, diagnosis and treatment of cancer by developing clinical and scientific research coupled with organisation and management. It provides a professional network for its members. History The European Institute of Oncology was conceived by Umberto Veronesi, who developed a new model for health and advanced research in the international oncology field. The institute was inaugurated in May 1994 and is today managed by Division and Unit Directors from eight European countries. The Institute became a research hospital and treatment centre (IRCCS or ) through the Ministerial Decree issued in January 1996. The European Ins ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ecosystem
An ecosystem (or ecological system) consists of all the organisms and the physical environment with which they interact. These biotic and abiotic components are linked together through nutrient cycles and energy flows. Energy enters the system through photosynthesis and is incorporated into plant tissue. By feeding on plants and on one another, animals play an important role in the movement of matter and energy through the system. They also influence the quantity of plant and microbial biomass present. By breaking down dead organic matter, decomposers release carbon back to the atmosphere and facilitate nutrient cycling by converting nutrients stored in dead biomass back to a form that can be readily used by plants and microbes. Ecosystems are controlled by external and internal factors. External factors such as climate, parent material which forms the soil and topography, control the overall structure of an ecosystem but are not themselves influenced by the ecosystem. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Computational Model
A computational model uses computer programs to simulate and study complex systems using an algorithmic or mechanistic approach and is widely used in a diverse range of fields spanning from physics, chemistry and biology to economics, psychology, cognitive science and computer science. The system under study is often a complex nonlinear system for which simple, intuitive analytical solutions are not readily available. Rather than deriving a mathematical analytical solution to the problem, experimentation with the model is done by adjusting the parameters of the system in the computer, and studying the differences in the outcome of the experiments. Operation theories of the model can be derived/deduced from these computational experiments. Examples of common computational models are weather forecasting models, earth simulator models, flight simulator models, molecular protein folding models, and neural network models. See also * Computational cognition *Reversible computing ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Population
Population typically refers to the number of people in a single area, whether it be a city or town, region, country, continent, or the world. Governments typically quantify the size of the resident population within their jurisdiction using a census, a process of collecting, analysing, compiling, and publishing data regarding a population. Perspectives of various disciplines Social sciences In sociology and population geography, population refers to a group of human beings with some predefined criterion in common, such as location, race, ethnicity, nationality, or religion. Demography is a social science which entails the statistical study of populations. Ecology In ecology, a population is a group of organisms of the same species who inhabit the same particular geographical area and are capable of interbreeding. The area of a sexual population is the area where inter-breeding is possible between any pair within the area and more probable than cross-breeding with in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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