Swiss Markings
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Swiss Markings
{{Unreferenced, date=June 2019, bot=noref (GreenC bot) Goats expressing the Swiss Marked pattern have a black (eumelanin pigment) body and belly and tan (phaeomelanin pigment) legs, ears, and facial stripes. The allele which codes for this pattern is located at the agouti locus of the goat genome. There are multiple modifier genes which control how much tan pigment is actually expressed and so the tan areas can range from pure white to deep red. There may also be present dilution genes which turn the black areas in the pattern to either chocolate or medium brown. Image:Toggenburger.jpg, A Toggenburg goat with Swiss Markings. Note that these Toggenburgs have modifier genes Epistasis is a phenomenon in genetics in which the effect of a gene mutation is dependent on the presence or absence of mutations in one or more other genes, respectively termed modifier genes. In other words, the effect of the mutation is dep ... which turn the black-pigmented areas to medium brown and ...
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Goats
The goat or domestic goat (''Capra hircus'') is a domesticated species of Caprinae, goat-antelope typically kept as livestock. It was domesticated from the wild goat (''C. aegagrus'') of Southwest Asia and Eastern Europe. The goat is a member of the animal family Bovidae and the tribe Caprini, meaning it is closely related to the sheep. There are over 300 distinct breeds of goat.Hirst, K. Kris"The History of the Domestication of Goats".''About.com''. Accessed August 18, 2008. It is one of the oldest domesticated species of animal, according to archaeological evidence that its earliest domestication occurred in Iran at 10,000 calibrated calendar years ago. Goats have been used for milk, Goat meat, meat, Animal fur, fur, and Animal skin, skins across much of the world. Milk from goats is often turned into goat cheese. Female goats are referred to as ''does'' or ''nannies'', Entire (animal), intact males are called ''bucks'' or ''billies'', and juvenile goats of both sexes are ...
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Eumelanin
Melanin (; from el, μέλας, melas, black, dark) is a broad term for a group of natural pigments found in most organisms. Eumelanin is produced through a multistage chemical process known as melanogenesis, where the oxidation of the amino acid tyrosine is followed by polymerization. The melanin pigments are produced in a specialized group of cells known as melanocytes. Functionally, eumelanin serves as protection against UV radiation. There are five basic types of melanin: eumelanin, pheomelanin, neuromelanin, allomelanin and pyomelanin. The most common type is eumelanin, of which there are two types— brown eumelanin and black eumelanin. Pheomelanin, which is produced when melanocytes are malfunctioning due to derivation of the gene to its recessive format is a cysteine-derivative that contains poly benzothiazine portions that are largely responsible for the of red yellow tint given to some skin or hair colors. Neuromelanin is found in the brain. Research has been u ...
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Phaeomelanin
Melanin (; from el, μέλας, melas, black, dark) is a broad term for a group of natural pigments found in most organisms. Eumelanin is produced through a multistage chemical process known as melanogenesis, where the oxidation of the amino acid tyrosine is followed by polymerization. The melanin pigments are produced in a specialized group of cells known as melanocytes. Functionally, eumelanin serves as protection against UV radiation. There are five basic types of melanin: eumelanin, pheomelanin, neuromelanin, allomelanin and pyomelanin. The most common type is eumelanin, of which there are two types— brown eumelanin and black eumelanin. Pheomelanin, which is produced when melanocytes are malfunctioning due to derivation of the gene to its recessive format is a cysteine-derivative that contains poly benzothiazine portions that are largely responsible for the of red yellow tint given to some skin or hair colors. Neuromelanin is found in the brain. Research has been under ...
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Allele
An allele (, ; ; modern formation from Greek ἄλλος ''állos'', "other") is a variation of the same sequence of nucleotides at the same place on a long DNA molecule, as described in leading textbooks on genetics and evolution. ::"The chromosomal or genomic location of a gene or any other genetic element is called a locus (plural: loci) and alternative DNA sequences at a locus are called alleles." The simplest alleles are single nucleotide polymorphisms (SNP). but they can also be insertions and deletions of up to several thousand base pairs. Popular definitions of 'allele' typically refer only to different alleles within genes. For example, the ABO blood grouping is controlled by the ABO gene, which has six common alleles (variants). In population genetics, nearly every living human's phenotype for the ABO gene is some combination of just these six alleles. Most alleles observed result in little or no change in the function of the gene product it codes for. However, ...
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Agouti Locus
The agouti (, ) or common agouti is any of several rodent species of the genus ''Dasyprocta''. They are native to Middle America, northern and central South America, and the southern Lesser Antilles. Some species have also been introduced elsewhere in the West Indies. They are related to guinea pigs and look quite similar, but they are larger and have longer legs. The species vary considerably in colour, being brown, reddish, dull orange, greyish, or blackish, but typically with lighter underparts. Their bodies are covered with coarse hair, which is raised when alarmed. They weigh and are in length, with short, hairless tails. The related pacas were placed by some authorities in a genus called ''Agouti'', though ''Cuniculus'' has priority and is the correct term. In West Africa (especially Ivory Coast), the name "agouti" designates the greater cane rat which, while an agricultural pest, is often sought as a bushmeat delicacy. The Spanish term is ''agutí.'' In Mexico, the ...
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Genome
In the fields of molecular biology and genetics, a genome is all the genetic information of an organism. It consists of nucleotide sequences of DNA (or RNA in RNA viruses). The nuclear genome includes protein-coding genes and non-coding genes, other functional regions of the genome such as regulatory sequences (see non-coding DNA), and often a substantial fraction of 'junk' DNA with no evident function. Almost all eukaryotes have mitochondria and a small mitochondrial genome. Algae and plants also contain chloroplasts with a chloroplast genome. The study of the genome is called genomics. The genomes of many organisms have been sequenced and various regions have been annotated. The International Human Genome Project reported the sequence of the genome for ''Homo sapiens'' in 200The Human Genome Project although the initial "finished" sequence was missing 8% of the genome consisting mostly of repetitive sequences. With advancements in technology that could handle sequenci ...
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Epistasis
Epistasis is a phenomenon in genetics in which the effect of a gene mutation is dependent on the presence or absence of mutations in one or more other genes, respectively termed modifier genes. In other words, the effect of the mutation is dependent on the genetic background in which it appears. Epistatic mutations therefore have different effects on their own than when they occur together. Originally, the term ''epistasis'' specifically meant that the effect of a gene variant is masked by that of a different gene. The concept of ''epistasis'' originated in genetics in 1907 but is now used in biochemistry, computational biology and evolutionary biology. The phenomenon arises due to interactions, either between genes (such as mutations also being needed in regulators of gene expression) or within them (multiple mutations being needed before the gene loses function), leading to non-linear effects. Epistasis has a great influence on the shape of evolutionary landscapes, which l ...
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Dilution Gene
A dilution gene is any one of a number of genes that act to create a lighter coat color in living creatures. There are many examples of such genes: General Diluted coat colors have melanocytes, but vary from darker colors due to the concentration or type of these pigment-producing cells, not their absence. Pigment dilution, sometimes referred to as hypomelanism, has been called leucism, albinism (perfect, impartial, or dilute), ghosting, paling, and isabellinism. *Albinism describes a condition where pigment cells synthesize little or no pigment *Leucism describes a condition that creates loss of pigment cells Cats *Cat coat genetics discusses many dilution genes in cats Dogs In dogs, a mutation of the MLPH locus known as the dilute gene causes eumelanin to lighten while pheomelanin remains almost unchanged. Dogs of some breeds with the dilute gene often suffer from Colour dilution alopecia (CDA). Appearance Of the colour shades found in the coat of dogs, the light brown cau ...
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Toggenburg Goat
The Toggenburger or Toggenburg is a Swiss List of goat breeds, breed of dairy goat. Its name derives from that of the Toggenburg (Switzerland), Toggenburg region of the Canton of St. Gallen, where it is thought to have originated. It is among the most productive breeds of dairy goat and is distributed world-wide, in about fifty countries in all five inhabited continents. History The Toggenburger is the traditional goat breed of the Toggenburg (Switzerland), Toggenburg and Werdenberg (Wahlkreis), Werdenberg regions of the Canton of St. Gallen in eastern Switzerland. The herd-book was started in 1890. At first, the goats were often dark-coated, sometimes with white markings; there may have been some cross-breeding with Appenzell (goat), Appenzell and Chamois-coloured Goat, Chamois-coloured stock in neighbouring areas. The typical mouse-grey colour with white Swiss markings, facial markings was fixed by selective breeding in the twentieth century. In 2006 there were 850 goats ...
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