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Streptomyces Spectabilis
''Streptomyces spectabilis'' is a bacterium species from the genus of ''Streptomyces''.Deutsche Sammlung von Mikroorganismen und Zellkulturenbr>/ref> ''Streptomyces spectabilis'' produces hangtaimycin, gentamicin, kanamycin, neomycin B, sisomycin, tobramycin, paromomycin, spectinabilin, spectinomycin, aminocyclitol, actinospectacin, prodigiosine and the streptovaricin complex. Further reading * * * * * * * * * * * See also * List of Streptomyces species A ''list'' is any set of items in a row. List or lists may also refer to: People * List (surname) Organizations * List College, an undergraduate division of the Jewish Theological Seminary of America * SC Germania List The SC Germania ... References External linksType strain of ''Streptomyces spectabilis'' at Bac''Dive'' - the Bacterial Diversity Metadatabase spectabilis Bacteria described in 1961 {{Streptomyces-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bacteria
Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among the first life forms to appear on Earth, and are present in most of its habitats. Bacteria inhabit soil, water, acidic hot springs, radioactive waste, and the deep biosphere of Earth's crust. Bacteria are vital in many stages of the nutrient cycle by recycling nutrients such as the fixation of nitrogen from the atmosphere. The nutrient cycle includes the decomposition of dead bodies; bacteria are responsible for the putrefaction stage in this process. In the biological communities surrounding hydrothermal vents and cold seeps, extremophile bacteria provide the nutrients needed to sustain life by converting dissolved compounds, such as hydrogen sulphide and methane, to energy. Bacteria also live in symbiotic and parasitic re ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Streptovaricin
Streptovaricins are a group of structurally related macrolide antibiotics. They belong to the larger class of antibiotics known as ansamycins. References Macrolide antibiotics Ansamycins {{antibiotic-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Actinospectacin
Spectinomycin, sold under the tradename Trobicin among others, is an antibiotic useful for the treatment of gonorrhea infections. It is given by injection into a muscle. Common side effects include pain at the area of injection, rash, nausea, fever, and trouble sleeping. Severe allergic reactions may occasionally occur. It is generally safe to use during pregnancy. It may be used by those who are allergic to penicillin or cephalosporins. It is in the aminocyclitol class of drugs and works by stopping the making of protein by certain bacteria. Spectinomycin was discovered in 1961. It is on the World Health Organization's List of Essential Medicines. It is not available in the United States for human use. It is made from the bacterium '' Streptomyces spectabilis''. Medical uses It is given by intramuscular injection to treat gonorrhea, especially in patients who are allergic to penicillins. This antibiotic is no longer available in the United States for human use, but is s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aminocyclitol
The aminocyclitols are compounds related to cyclitols. They possess features of relative and absolute configuration that are characteristic of their class and have been extensively studied; but these features are not clearly displayed by general methods of stereochemical nomenclature, so that special methods of specifying their configuration are justified and have long been used. In other than stereochemical respects, their nomenclature should follow the general rules of organic chemistry. Aminocyclitol natural products The aminocyclitol family of natural products is a class of sugar-derived microbial secondary metabolites that demonstrate significant biological activities. Aminocyclitols are found as a component of aminoglycoside antibiotics which is also called as pseudosugars or pseudosaccharides. Aminocyclitols have chemical structures of a carbon ring with amine functional group(s). The class of aminocyclitol containing natural products can be divided by ring sizes or types ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spectinomycin
Spectinomycin, sold under the tradename Trobicin among others, is an antibiotic useful for the treatment of gonorrhea infections. It is given by injection into a muscle. Common side effects include pain at the area of injection, rash, nausea, fever, and trouble sleeping. Severe allergic reactions may occasionally occur. It is generally safe to use during pregnancy. It may be used by those who are allergic to penicillin or cephalosporins. It is in the aminocyclitol class of drugs and works by stopping the making of protein by certain bacteria. Spectinomycin was discovered in 1961. It is on the World Health Organization's List of Essential Medicines. It is not available in the United States for human use. It is made from the bacterium '' Streptomyces spectabilis''. Medical uses It is given by intramuscular injection to treat gonorrhea, especially in patients who are allergic to penicillins. This antibiotic is no longer available in the United States for human use, but is still ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spectinabilin
Spectinabilin is a nitrophenyl-substituted polyketide metabolite. It was first isolated from crude streptovaricin complex produced by '' Streptomyces spectabilis'' and presented at the 13th Interscience Conference on Antimicrobial Agents and Chemotherapy in Washington, D.C. in September 1973. Spectinabilin is a biologically active compound, exhibiting both antimalarial and antiviral activity.'' Biosynthesis Production of spectinabilin occurs through a type one polyketide synthase, and is regulated differently in ''S. spectabilis'' and '' Streptomyces orinoci'' despite being nearly identical gene clusters. The biosynthesis of Spectinabillin initially requires 4 open reading frames (ORF) for the production of the starter unit, p-nitrobenzoic acid (pNBA) from chorismate. pNBA is then loaded onto the polyketide synthase, and undergoes 6 rounds of elongation and reduction. Briefly, pNBA is loaded onto the PKA and elongated by methyl malonyl-coa (mmCoA), which is then reduced twi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Paromomycin
Paromomycin is an antimicrobial used to treat a number of parasitic infections including amebiasis, giardiasis, leishmaniasis, and tapeworm infection. It is a first-line treatment for amebiasis or giardiasis during pregnancy. Otherwise it is generally a second line treatment option. It is taken by mouth, applied to the skin, or by injection into a muscle. Common side effects when taken by mouth include loss of appetite, vomiting, abdominal pain, and diarrhea. When applied to the skin side effects include itchiness, redness, and blisters. When given by injection there may be fever, liver problems, or hearing loss. Use during breastfeeding appears to be safe. Paromomycin is in the aminoglycoside family of medications and causes microbe death by stopping the creation of bacterial proteins. Paromomycin was discovered in the 1950s from a type of streptomyces and came into medical use in 1960. It is on the World Health Organization's List of Essential Medicines. Paromomycin is ava ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tobramycin
Tobramycin is an aminoglycoside antibiotic derived from ''Streptomyces tenebrarius'' that is used to treat various types of bacterial infections, particularly Gram-negative infections. It is especially effective against species of ''Pseudomonas''. It was patented in 1965, and approved for medical use in 1974. It is on the World Health Organization's List of Essential Medicines. Medical uses Like all aminoglycosides, tobramycin does not pass the gastro-intestinal tract, so for systemic use it can only be given intravenously or by injection into a muscle. Eye drops and ointments (tobramycin only, Tobrex, or combined with dexamethasone, sold as Tobradex) and nebulised formulations both have low systemic absorption. The formulation for injection is branded Nebcin. The nebulised formulation (brand name Tobi) is indicated in the treatment of exacerbations of chronic infection with ''Pseudomonas aeruginosa'' in people diagnosed with cystic fibrosis. Tobrex eye drops are a 0. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neomycin B
Neomycin is an aminoglycoside antibiotic that displays bactericidal activity against gram-negative aerobic bacilli and some anaerobic bacilli where resistance has not yet arisen. It is generally not effective against gram-positive bacilli and anaerobic gram-negative bacilli. Neomycin comes in oral and topical formulations, including creams, ointments, and eyedrops. Neomycin belongs to the aminoglycoside class of antibiotics that contain two or more amino sugars connected by glycosidic bonds. Neomycin was discovered in 1949 by microbiologist Selman Waksman and his student Hubert Lechevalier at Rutgers University. Neomycin received approval for medical use in 1952. Rutgers University was granted the patent for neomycin in 1957. Discovery Neomycin was discovered in 1949 by the microbiologist Selman Waksman and his student Hubert Lechevalier at Rutgers University. It is produced naturally by the bacterium ''Streptomyces fradiae''. Synthesis requires specific nutrient con ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Actinomycetota
The ''Actinomycetota'' (or ''Actinobacteria'') are a phylum of all gram-positive bacteria. They can be terrestrial or aquatic. They are of great economic importance to humans because agriculture and forests depend on their contributions to soil systems. In soil they help to decompose the organic matter of dead organisms so the molecules can be taken up anew by plants. While this role is also played by fungi, ''Actinomycetota'' are much smaller and likely do not occupy the same ecological niche. In this role the colonies often grow extensive mycelia, like a fungus would, and the name of an important order of the phylum, '' Actinomycetales'' (the actinomycetes), reflects that they were long believed to be fungi. Some soil actinomycetota (such as ''Frankia'') live symbiotically with the plants whose roots pervade the soil, fixing nitrogen for the plants in exchange for access to some of the plant's saccharides. Other species, such as many members of the genus ''Mycobacterium'', ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
