Strangeways Laboratory
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Strangeways Laboratory
Strangeways Research Laboratory is a research institution in Cambridge, United Kingdom. It was founded by Thomas Strangeways in 1905 as the Cambridge Research Hospital and acquired its current name in 1928. Organised as an independent charity, it was historically funded primarily by the Medical Research Council and is currently managed by the University of Cambridge, also its sole trustee. Formerly a site of research on rheumatic arthritis and connective tissue disorders, it has since 1997 focused on the study of genetic epidemiology. History The institution was founded in 1905 as the Cambridge Research Hospital by physician Thomas Strangeways, who sought to study patients suffering from rheumatoid arthritis and related conditions. Funded by a combination of Strangeways' own contributions, support from noted doctors of the time, and donations from patients, the hospital began modestly with only six beds, and with research equipment located in renovated coal sheds. It closed ...
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Thomas Strangeways Wellcome L0003592
Thomas may refer to: People * List of people with given name Thomas * Thomas (name) * Thomas (surname) * Saint Thomas (other) * Thomas Aquinas (1225–1274) Italian Dominican friar, philosopher, and Doctor of the Church * Thomas the Apostle * Thomas (bishop of the East Angles) (fl. 640s–650s), medieval Bishop of the East Angles * Thomas (Archdeacon of Barnstaple) (fl. 1203), Archdeacon of Barnstaple * Thomas, Count of Perche (1195–1217), Count of Perche * Thomas (bishop of Finland) (1248), first known Bishop of Finland * Thomas, Earl of Mar (1330–1377), 14th-century Earl, Aberdeen, Scotland Geography Places in the United States * Thomas, Illinois * Thomas, Indiana * Thomas, Oklahoma * Thomas, Oregon * Thomas, South Dakota * Thomas, Virginia * Thomas, Washington * Thomas, West Virginia * Thomas County (other) * Thomas Township (other) Elsewhere * Thomas Glacier (Greenland) Arts, entertainment, and media *Thomas (Burton novel), ''Thomas'' (Bur ...
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Honor Fell's Lab Desk At Strangeways Wellcome L0073410
Honour (British English) or honor (American English; see spelling differences) is the idea of a bond between an individual and a society as a quality of a person that is both of social teaching and of personal ethos, that manifests itself as a code of conduct, and has various elements such as valour, chivalry, honesty, and compassion. It is an abstract concept entailing a perceived quality of worthiness and respectability that affects both the social standing and the self-evaluation of an individual or institutions such as a family, school, regiment or nation. Accordingly, individuals (or institutions) are assigned worth and stature based on the harmony of their actions with a specific code of honour, and the moral code of the society at large. Samuel Johnson, in his ''A Dictionary of the English Language'' (1755), defined honour as having several senses, the first of which was "nobility of soul, magnanimity, and a scorn of meanness". This sort of honour derives from the percei ...
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Genetics In The United Kingdom
Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today, is a somewhat ambiguous definition of what is referred to as a gene. Trait inheritance and molecular inheritance mechanisms of genes are still primary principles of genetics in the 21st century, but modern genetics has expanded to study the function and behavior of genes. Gene structure and function, variation, and distribution are studied within the context of the cell, the organism (e.g. dominance), and within the context ...
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Bruce Ponder
Sir Bruce Anthony John Ponder FMedSci FAACR FRS (born 25 April 1944) is an English geneticist and cancer researcher. He is Emeritus Professor of Oncology at the University of Cambridge and former director of the Cancer Research UK Cambridge Institute and of the Cancer Research UK Cambridge Cancer Centre. Education Ponder was educated at Charterhouse School and Jesus College, Cambridge. He trained in medicine at St Thomas' Hospital, London, and carried out his PhD studies as an Imperial Cancer Research Fund Clinical Fellow with Lionel Crawford in London working on chromatin organisation and DNA sequence specificity using polyoma virus. Research After completing training in medical oncology, Ponder obtained a 5 year Career Development award from the UK Cancer Research Campaign at the Royal Marsden Hospital and Institute for Cancer Research, London, in which he combined laboratory and clinical research.  He first studied cancer as a breakdown of the normal rules of tissue o ...
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Nick Day (statistician)
Nicholas Edward Day, CBE, FRS (born 24 September 1939) is a retired statistician and cancer epidemiologist. Education He was educated at Gresham's School and the University of Oxford, from 1958-1962, where he gained a B.A. in Mathematics and a Diploma in Statistics, and the University of Aberdeen from 1962-1966, where he obtained a Doctorate of Philosophy. Career Day worked at the International Agency for Research on Cancer in Lyon from 1969 to 1986, where he rose to become head of the Unit of Biostatistics and Field Studies. He was director of the Medical Research Council Biostatistics Unit from 1986 to 1989, and continued as honorary director until 1999. From 1997 until his retirement in 2004 he was co-director of the Strangeways Research Laboratory in Cambridge. He was also professor of public health at the University of Cambridge from 1989 to 1999, and professor of epidemiology from 1999 until 2004. Day was made a Commander of the Order of the British Empire in the 2001 N ...
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John T
John is a common English name and surname: * John (given name) * John (surname) John may also refer to: New Testament Works * Gospel of John, a title often shortened to John * First Epistle of John, often shortened to 1 John * Second Epistle of John, often shortened to 2 John * Third Epistle of John, often shortened to 3 John People * John the Baptist (died c. AD 30), regarded as a prophet and the forerunner of Jesus Christ * John the Apostle (lived c. AD 30), one of the twelve apostles of Jesus * John the Evangelist, assigned author of the Fourth Gospel, once identified with the Apostle * John of Patmos, also known as John the Divine or John the Revelator, the author of the Book of Revelation, once identified with the Apostle * John the Presbyter, a figure either identified with or distinguished from the Apostle, the Evangelist and John of Patmos Other people with the given name Religious figures * John, father of Andrew the Apostle and Saint Peter * Pope Joh ...
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John Danesh
John Danesh is a Professor of Epidemiology and Medicine and the head of the Department of Public Health and Primary Care at the University of Cambridge. He also holds several other leadership roles in scientific organizations, including director of the department's affiliate Strangeways Research Laboratory and founder and director of the Cardiovascular Epidemiology Unit. He is also an associate faculty member at the Wellcome Trust Sanger Institute and an honorary consultant at the Cambridge University Hospitals NHS Foundation Trust. He became a fellow of the Royal College of Physicians in 2007 and of the Academy of Medical Sciences in 2015. Professor Danesh has been the British Heart Foundation Professor of Medicine and Epidemiology since 2012. In 2013 he won the Senior Investigator award from the National Institute for Health and Care Research (NIHR). Education Danesh was educated in New Zealand and Australia, studying medicine at the University of Otago in and the Royal Melbourne ...
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Francis Crick
Francis Harry Compton Crick (8 June 1916 – 28 July 2004) was an English molecular biologist, biophysicist, and neuroscientist. He, James Watson, Rosalind Franklin, and Maurice Wilkins played crucial roles in deciphering the helical structure of the DNA molecule. Crick and Watson's paper in ''Nature'' in 1953 laid the groundwork for understanding DNA structure and functions. Together with Maurice Wilkins, they were jointly awarded the 1962 Nobel Prize in Physiology or Medicine "for their discoveries concerning the molecular structure of nucleic acids and its significance for information transfer in living material". Crick was an important theoretical molecular biologist and played a crucial role in research related to revealing the helical structure of DNA. He is widely known for the use of the term " central dogma" to summarise the idea that once information is transferred from nucleic acids (DNA or RNA) to proteins, it cannot flow back to nucleic acids. In other words ...
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Basic Research
Basic research, also called pure research or fundamental research, is a type of scientific research with the aim of improving scientific theories for better understanding and prediction of natural or other phenomena. In contrast, applied research uses scientific theories to develop technology or techniques which can be used to intervene and ''alter'' natural or other phenomena. Though often driven simply by curiosity,"Curiosity creates cures: The value and impact of basic research
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Radiobiology
Radiobiology (also known as radiation biology, and uncommonly as actinobiology) is a field of clinical and basic medical sciences that involves the study of the action of ionizing radiation on living things, especially health effects of radiation. Ionizing radiation is generally harmful and potentially lethal to living things but can have health benefits in radiation therapy for the treatment of cancer and thyrotoxicosis. Its most common impact is the induction of cancer with a latent period of years or decades after exposure. High doses can cause visually dramatic radiation burns, and/or rapid fatality through acute radiation syndrome. Controlled doses are used for medical imaging and radiotherapy. Health effects In general, ionizing radiation is harmful and potentially lethal to living beings but can have health benefits in radiation therapy for the treatment of cancer and thyrotoxicosis. Most adverse health effects of radiation exposure may be grouped in two general categori ...
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Michael Abercrombie
Michael Abercrombie FRS (14 August 1912 – 28 May 1979) was a British cell biologist and embryologist. He was one of four children of the poet Lascelles Abercrombie. Early life Michael was born at Ryton near Dymock in Gloucestershire on 14 August 1912, the third son of Lascelles Abercrombie, poet and critic, and his wife, Catherine, daughter of Owen Gwatkin, a surgeon at Grange-over-Sands.Dictionary of National Biography 1971-1980 His uncle was the famed British town planner, Patrick Abercrombie. Abercrombie went to school at Liverpool College and then Leeds Grammar School. In 1931 he entered Queen's College, University of Oxford, to study Zoology under Professor Gavin de Beer, supported by a Hastings scholarship. He was awarded a first class B. Sc. degree in 1934. Later life He moved to the Strangeways Research Laboratory at the University of Cambridge to undertake doctoral research. In 1938 was employed at University of Birmingham as a lecturer, while also holding a resea ...
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Organ Culture
Organ culture is a development from tissue culture methods of research, the organ culture is able to accurately model functions of an organ in various states and conditions by the use of the actual ''in vitro'' organ itself. Parts of an organ or a whole organ can be cultured in vitro. The main objective is to maintain the architecture of the tissue and direct it towards normal development. In this technique, it is essential that the tissue is never disrupted or damaged. It thus requires careful handling. The media used for a growing organ culture are generally the same as those used for tissue culture. The techniques for organ culture can be classified into (i) those employing a solid medium and (ii) those employing liquid medium. Current progress In April 2006, scientists reported a successful trial of seven bladders grown in-vitro and given to humans. A bladder has been cultured by Anthony Atala of the Wake Forest Institute for Regenerative Medicine in Winston-Salem, North Caro ...
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