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Bruce Ponder
Sir Bruce Anthony John Ponder FMedSci FAACR FRS (born 25 April 1944) is an English geneticist and cancer researcher. He is Emeritus Professor of Oncology at the University of Cambridge and former director of the Cancer Research UK Cambridge Institute and of the Cancer Research UK Cambridge Cancer Centre. Education Ponder was educated at Charterhouse School and Jesus College, Cambridge. He trained in medicine at St Thomas' Hospital, London, and carried out his PhD studies as an Imperial Cancer Research Fund Clinical Fellow with Lionel Crawford in London working on chromatin organisation and DNA sequence specificity using polyoma virus. Research After completing training in medical oncology, Ponder obtained a 5 year Career Development award from the UK Cancer Research Campaign at the Royal Marsden Hospital and Institute for Cancer Research, London, in which he combined laboratory and clinical research. He first studied cancer as a breakdown of the normal rules of tissue o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polyoma Virus
''Polyomaviridae'' is a family of viruses whose natural hosts are primarily mammals and birds. As of 2020, there are six recognized genera and 117 species, five of which are unassigned to a genus. 14 species are known to infect humans, while others, such as Simian Virus 40, have been identified in humans to a lesser extent. Most of these viruses are very common and typically asymptomatic in most human populations studied. BK virus is associated with nephropathy in renal transplant and non-renal solid organ transplant patients, JC virus with progressive multifocal leukoencephalopathy, and Merkel cell virus with Merkel cell cancer. Structure and genome Polyomaviruses are non-enveloped double-stranded DNA viruses with circular genomes of around 5000 base pairs. The genome is packaged in a viral capsid of about 40-50 nanometers in diameter, which is icosahedral in shape (T=7 symmetry). The capsid is composed of 72 pentameric capsomeres of a protein called VP1, which is capable of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Translational Research
Translational research (also called translation research, translational science, or, when the context is clear, simply translation) is research aimed at translating (converting) results in basic research into results that directly benefit humans. The term is used in science and technology, especially in biology and medical science. As such, translational research forms a subset of applied research. The term has been used most commonly in life-sciences and biotechnology but applies across the spectrum of science and humanities. In the context of biomedicine, translational research is also known as bench to bedside. In the field of education, it is defined as research which translates concepts to classroom practice. Critics of translational medical research (to the exclusion of more basic research) point to examples of important drugs that arose from fortuitous discoveries in the course of basic research such as penicillin and benzodiazepines. Other problems have stemmed from the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Basic Science
Basic research, also called pure research or fundamental research, is a type of scientific research with the aim of improving scientific theories for better understanding and prediction of natural or other phenomena. In contrast, applied research uses scientific theories to develop technology or techniques which can be used to intervene and ''alter'' natural or other phenomena. Though often driven simply by curiosity,"Curiosity creates cures: The value and impact of basic research , , |
Addenbrooke's Hospital
Addenbrooke's Hospital is an internationally renowned large teaching hospital and research centre in Cambridge, England, with strong affiliations to the University of Cambridge. Addenbrooke's Hospital is based on the Cambridge Biomedical Campus. The hospital is run by Cambridge University Hospitals NHS Foundation Trust and is a designated academic health science centre. It is also the East of England's major trauma centre and was the first such centre to be operational in the United Kingdom. History The hospital was founded in 1766 on Trumpington Street with £4,500 from the will of Dr John Addenbrooke, a fellow of St Catharine's College. In 1962 the first building was opened on its present site, on the southern edge of the city at the end of Hills Road. The last patient left the old site in 1984 - the old site is now occupied by the Cambridge Judge Business School, as well as Browns Brasserie & Bar. A new elective care facility was procured under a Private Finance Initi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Strangeways Research Laboratory
Strangeways Research Laboratory is a research institution in Cambridge, United Kingdom. It was founded by Thomas Strangeways in 1905 as the Cambridge Research Hospital and acquired its current name in 1928. Organised as an independent charity, it was historically funded primarily by the Medical Research Council and is currently managed by the University of Cambridge, also its sole trustee. Formerly a site of research on rheumatic arthritis and connective tissue disorders, it has since 1997 focused on the study of genetic epidemiology. History The institution was founded in 1905 as the Cambridge Research Hospital by physician Thomas Strangeways, who sought to study patients suffering from rheumatoid arthritis and related conditions. Funded by a combination of Strangeways' own contributions, support from noted doctors of the time, and donations from patients, the hospital began modestly with only six beds, and with research equipment located in renovated coal sheds. It closed b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Li Ka Shing
Sir Ka-shing Li (; born 13 June 1928) is a Hong Kong billionaire business magnate, investor, and philanthropist. As of June 2019, Li is the 31st richest person in the world, with an estimated net wealth of US$33.4 billion. He is the senior advisor for CK Hutchison Holdings and CK Asset Holdings, after he retired from the Chairman of the Board in May 2018; through it, he is the world's leading port investor, developer, and operator of the largest health and beauty retailer in Asia and Europe. Forbes magazine released its Hong Kong fortune league chart in February 2021, which showed that Li Ka-shing had reclaimed his prime position as Hong Kong's richest person, with his net assets topping US$35.40 billion. Li is one of the most influential entrepreneurs in Asia, presiding over a business empire with a diverse portfolio of businesses from a wide array of industries, including transportation, real estate, financial services, retail, and energy and utilities. His conglomerate comp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
St George's Hospital
St George's Hospital is a large teaching hospital in Tooting, London. Founded in 1733, it is one of the UK's largest teaching hospitals and one of the largest hospitals in Europe. It is run by the St George's University Hospitals NHS Foundation Trust. It shares its main hospital site in Tooting in the London Borough of Wandsworth, with St George's, University of London, which trains NHS staff and carries out advanced medical research. The hospital has around 1,300 beds and most general tertiary care such as accident and emergency, maternity services and care for older people and children. However, as a major acute hospital, St George's Hospital also offers specialist care for the more complex injuries and illnesses, including trauma, neurology, cardiac care, renal transplantation, cancer care and stroke. It is also home to one of four major trauma centres and one of eight hyper-acute stroke units for London. St George's Hospital also provides care for patients from a larger ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Guy's Hospital
Guy's Hospital is an NHS hospital in the borough of Southwark in central London. It is part of Guy's and St Thomas' NHS Foundation Trust and one of the institutions that comprise the King's Health Partners, an academic health science centre. It is a large teaching hospital and is, with St Thomas' Hospital and King's College Hospital, the location of King's College London GKT School of Medical Education. The hospital's Tower Wing (originally known as Guy's Tower) was, when built in 1974, the tallest hospital building in the world, standing at with 34 floors. The tower was overtaken as the world's tallest healthcare-related building by The Belaire in New York City in 1988. As of June 2019, the Tower Wing, which remains one of the tallest buildings in London, is the world's fifth-tallest hospital building. History The hospital dates from 1721, when it was founded by philanthropist Thomas Guy, who had made a fortune as a printer of Bibles and greatly increased it by speculat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Royal Marsden Hospital
The Royal Marsden Hospital (RM) is a specialist cancer treatment hospital in London based in Kensington and Chelsea, next to the Royal Brompton Hospital, in Fulham Road with a second site in Belmont, close to Sutton Hospital, High Down and Downview Prisons. It is managed by the Royal Marsden NHS Foundation Trust. History Canon Row The Royal Marsden was the first hospital in the world dedicated to the study and treatment of cancer. It was founded as the Free Cancer Hospital in 1851 by William Marsden at 1, Cannon Row, Westminster. Marsden, deeply affected by the death of his wife Elizabeth Ann from cancer, resolved to classify tumours, research the causes and find new treatments. The hospital at first consisted solely of a dispensary and the drugs prescribed were palliative and aimed at treating symptoms, but it allowed William Marsden the opportunity to study and research the disease. The hospital quickly outgrew its original premises as it became apparent that some p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harvard Medical School
Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consistently ranked first for research among medical schools by '' U.S. News & World Report''. Unlike most other leading medical schools, HMS does not operate in conjunction with a single hospital but is directly affiliated with several teaching hospitals in the Boston area. Affiliated teaching hospitals and research institutes include Dana–Farber Cancer Institute, Massachusetts General Hospital, Brigham and Women's Hospital, Beth Israel Deaconess Medical Center, Boston Children's Hospital, McLean Hospital, Cambridge Health Alliance, The Baker Center for Children and Families, and Spaulding Rehabilitation Hospital. History Harvard Medical School was founded on September 19, 1782, after President Joseph Willard presented a report with ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dana–Farber Cancer Institute
Dana–Farber Cancer Institute is a comprehensive cancer treatment and research institution in Boston, Massachusetts. Dana–Farber is the founding member of Dana–Farber/Harvard Cancer Center, Harvard's Comprehensive Cancer Center designated by the National Cancer Institute, and one of the 15 clinical affiliates and research institutes of Harvard Medical School. As of 2021, Dana–Farber is ranked the #3 cancer hospital in the world. Two Nobel laureates in Physiology or Medicine are among its past and present faculty. Dana–Farber's research discoveries include the development of the highly successful Gleevec to treat chronic myeloid leukemia. Overview Dana–Farber employs more than 4,855 full-time and part-time people, 529 faculty, and has annual gross revenues of about $1,733,386,000. All faculty and postdoctoral research fellows at Dana–Farber hold the equivalent academic positions concurrently at Harvard University. There are more than 523,425 adult and pediatric patie ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
