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Sporothrix Brasiliensis
''Sporothrix brasiliensis'' is a fungus that is commonly found in soil. It is an emerging fungal pathogen that is causing disease in humans and cats mainly in Brazil and other countries in South America. Similar to other species in ''Sporothrix'' genus, this fungus causes the disease sporotrichosis. However, it has been observed that more severe disease results from infection by ''Sporothrix brasiliensis'' compared to other species. The fungus is a thermally dimorphic fungus as it is found in the mycelium phase at room temperature and as yeast in the warmer temperatures of host bodies. Morphology The two morphologies displayed by ''Sporothrix brasiliensis'' are a hyphal form which occurs in the environment and a yeast form which occurs at higher temperatures (36 - 37 °C) such as within the bodies of mammals. Hyphal Phase The hyphal form of ''S.brasiliensis'' occurs at room temperature. Melaninization level of the hyphal form can vary from light (albino) to dark (pigm ...
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Fungi
A fungus ( : fungi or funguses) is any member of the group of eukaryotic organisms that includes microorganisms such as yeasts and molds, as well as the more familiar mushrooms. These organisms are classified as a kingdom, separately from the other eukaryotic kingdoms, which by one traditional classification include Plantae, Animalia, Protozoa, and Chromista. A characteristic that places fungi in a different kingdom from plants, bacteria, and some protists is chitin in their cell walls. Fungi, like animals, are heterotrophs; they acquire their food by absorbing dissolved molecules, typically by secreting digestive enzymes into their environment. Fungi do not photosynthesize. Growth is their means of mobility, except for spores (a few of which are flagellated), which may travel through the air or water. Fungi are the principal decomposers in ecological systems. These and other differences place fungi in a single group of related organisms, named the ''Eumycota'' (''t ...
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Colombia
Colombia (, ; ), officially the Republic of Colombia, is a country in South America with insular regions in North America—near Nicaragua's Caribbean coast—as well as in the Pacific Ocean. The Colombian mainland is bordered by the Caribbean Sea to the north, Venezuela to the east and northeast, Brazil to the southeast, Ecuador and Peru to the south and southwest, the Pacific Ocean to the west, and Panama to the northwest. Colombia is divided into 32 departments and the Capital District of Bogotá, the country's largest city. It covers an area of 1,141,748 square kilometers (440,831 sq mi), and has a population of 52 million. Colombia's cultural heritage—including language, religion, cuisine, and art—reflects its history as a Spanish colony, fusing cultural elements brought by immigration from Europe and the Middle East, with those brought by enslaved Africans, as well as with those of the various Amerindian civilizations that predate colonization. Spanish is th ...
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Itraconazole
Itraconazole, sometimes abbreviated ITZ, is an antifungal medication used to treat a number of fungal infections. This includes aspergillosis, blastomycosis, coccidioidomycosis, histoplasmosis, and paracoccidioidomycosis. It may be given by mouth or intravenously. Common side effects include nausea, diarrhea, abdominal pain, rash, and headache. Severe side effects may include liver problems, heart failure, Stevens–Johnson syndrome and allergic reactions including anaphylaxis. It is unclear if use during pregnancy or breastfeeding is safe. It is in the triazole family of medications. It stops fungal growth by affecting the cell membrane or affecting their metabolism. Itraconazole was patented in 1978 and approved for medical use in the United States in 1992. It is on the World Health Organization's List of Essential Medicines. Recent research works suggest itraconazole (ITZ) could also be used in the treatment of cancer by inhibiting the hedgehog pathway in a similar way to ...
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Amphotericin B
Amphotericin B is an antifungal medication used for serious fungal infections and leishmaniasis. The fungal infections it is used to treat include mucormycosis, aspergillosis, blastomycosis, candidiasis, coccidioidomycosis, and cryptococcosis. For certain infections it is given with flucytosine. It is typically given intravenously (injection into a vein). Common side effects include a reaction with fever, chills, and headaches soon after the medication is given, as well as kidney problems. Allergic symptoms including anaphylaxis may occur. Other serious side effects include low blood potassium and myocarditis (inflammation of the heart). It appears to be relatively safe in pregnancy. There is a lipid formulation that has a lower risk of side effects. It is in the polyene class of medications and works in part by interfering with the cell membrane of the fungus. Amphotericin B was isolated from '' Streptomyces nodosus'' in 1955 at the Squibb For Medical Research Institute from c ...
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Potassium Iodide
Potassium iodide is a chemical compound, medication, and dietary supplement. It is a medication used for treating hyperthyroidism, in radiation emergencies, and for protecting the thyroid gland when certain types of radiopharmaceuticals are used. In the third world it is also used for treating skin sporotrichosis and phycomycosis. It is a supplement used by people with low dietary intake of iodine. It is administered orally. Common side effects include vomiting, diarrhea, abdominal pain, rash, and swelling of the salivary glands. Other side effects include allergic reactions, headache, goitre, and depression. While use during pregnancy may harm the baby, its use is still recommended in radiation emergencies. Potassium iodide has the chemical formula K I. Commercially it is made by mixing potassium hydroxide with iodine. Potassium iodide has been used medically since at least 1820. It is on the World Health Organization's List of Essential Medicines. Potassium iodide is av ...
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Terbinafine
Terbinafine, sold under the brand name Lamisil among others, is an antifungal medication used to treat pityriasis versicolor, fungal nail infections, and ringworm including jock itch and athlete's foot. It is either taken by mouth or applied to the skin as a cream or ointment. The cream and ointment are not effective for nail infections. Common side effects when taken by mouth include nausea, diarrhea, headache, cough, rash, and elevated liver enzymes. Severe side effects include liver problems and allergic reactions. Liver injury is, however, unusual. Use during pregnancy is not typically recommended. The cream and ointment may result in itchiness but are generally well tolerated. Terbinafine is in the allylamines family of medications. It works by decreasing the ability of fungi to synthesize sterols. It appears to result in fungal cell death. Terbinafine was discovered in 1991. It is on the World Health Organization's List of Essential Medicines. In 2020, it was the 279th ...
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Itraconazole
Itraconazole, sometimes abbreviated ITZ, is an antifungal medication used to treat a number of fungal infections. This includes aspergillosis, blastomycosis, coccidioidomycosis, histoplasmosis, and paracoccidioidomycosis. It may be given by mouth or intravenously. Common side effects include nausea, diarrhea, abdominal pain, rash, and headache. Severe side effects may include liver problems, heart failure, Stevens–Johnson syndrome and allergic reactions including anaphylaxis. It is unclear if use during pregnancy or breastfeeding is safe. It is in the triazole family of medications. It stops fungal growth by affecting the cell membrane or affecting their metabolism. Itraconazole was patented in 1978 and approved for medical use in the United States in 1992. It is on the World Health Organization's List of Essential Medicines. Recent research works suggest itraconazole (ITZ) could also be used in the treatment of cancer by inhibiting the hedgehog pathway in a similar way to ...
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Sporothrix Schenckii
''Sporothrix schenckii'', a fungus that can be found worldwide in the environment, is named for medical student Benjamin Schenck, who in 1896 was the first to isolate it from a human specimen. The species is present in soil as well as in and on living and decomposing plant material such as peat moss. It can infect humans as well as animals and is the causative agent of sporotrichosis, commonly known as "rose handler's disease." The most common route of infection is the introduction of spores to the body through a cut or puncture wound in the skin. Infection commonly occurs in otherwise healthy individuals but is rarely life-threatening and can be treated with antifungals. In the environment it is found growing as filamentous hyphae. In host tissue it is found as a yeast. The transition between the hyphal and yeast forms is temperature dependent making ''S. schenckii'' a thermally dimorphic fungus. Morphology ''Sporothrix schenckii'' can be found in one of two morphologies, hy ...
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Sporotrichosis
Sporotrichosis, also known as rose handler's disease, is a fungal infection that affects skin, lungs, bone and joint, and can be widespread. It presents with firm painless Nodule (medicine), nodules that later ulceration, ulcerate. It can be localized or widespread. The disease progresses over a week to several months after the initial exposure to the fungus. Serious complications can also develop in people who have a immunosuppression, weakened immune system. Sporotrichosis is caused by fungi of the ''Sporothrix schenckii'' species complex. Because ''S. schenckii'' is naturally found in soil, hay, sphagnum moss, and plants, it usually affects farmers, gardeners, and agricultural workers. It enters through small cuts in the skin to cause the infection. In case of sporotrichosis affecting the lungs, the fungal spores enter by inhalation, breathing in. Sporotrichosis can also be acquired from handling cats with the disease; it is an occupational hazard for veterinarians. Treatment ...
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Feline Sporotrichosis 3
Feline may refer to: Zoology * Loosely, Felidae, a member of the cat family, which includes the subfamilies Pantherinae and Felinae (conventionally designated a felid) ** Following the taxonomic convention, Felinae, the subfamily of Felidae that includes domestic cats and smaller wild cats *** Cat, the domesticated feline Music * Feline (band), a late-1990s London-based English rock group * ''Feline'' (The Stranglers album), 1983 * ''Feline'' (1998 album), the self-titled album by Feline, expanded release of ''Save Your Face'' * ''Feline'' (Ella Eyre album) (2015), the debut studio album by Ella Eyre * Feline (song), a song on Delta Goodrem's 2016 album ''Wings of the Wild'' * Feline (song) ''Wings of the Wild'' is the fifth studio album by Australian singer-songwriter Delta Goodrem. It was released on 1 July 2016, through Sony Music Australia. A follow-up to her last studio album, '' Child of the Universe'' (2012), it was her first ..., a song by Juice World Feat. Polo G. Co ...
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Panama
Panama ( , ; es, link=no, Panamá ), officially the Republic of Panama ( es, República de Panamá), is a transcontinental country spanning the southern part of North America and the northern part of South America. It is bordered by Costa Rica to the west, Colombia to the southeast, the Caribbean Sea to the north, and the Pacific Ocean to the south. Its capital and largest city is Panama City, whose metropolitan area is home to nearly half the country's million people. Panama was inhabited by indigenous tribes before Spanish colonists arrived in the 16th century. It broke away from Spain in 1821 and joined the Republic of Gran Colombia, a union of Nueva Granada, Ecuador, and Venezuela. After Gran Colombia dissolved in 1831, Panama and Nueva Granada eventually became the Republic of Colombia. With the backing of the United States, Panama seceded from Colombia in 1903, allowing the construction of the Panama Canal to be completed by the United States Army Corps of En ...
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Bolivia
, image_flag = Bandera de Bolivia (Estado).svg , flag_alt = Horizontal tricolor (red, yellow, and green from top to bottom) with the coat of arms of Bolivia in the center , flag_alt2 = 7 × 7 square patchwork with the (top left to bottom right) diagonals forming colored stripes (green, blue, purple, red, orange, yellow, white, green, blue, purple, red, orange, yellow, from top right to bottom left) , other_symbol = , other_symbol_type = Dual flag: , image_coat = Escudo de Bolivia.svg , national_anthem = " National Anthem of Bolivia" , image_map = BOL orthographic.svg , map_width = 220px , alt_map = , image_map2 = , alt_map2 = , map_caption = , capital = La Paz Sucre , largest_city = , official_languages = Spanish , languages_type = Co-official languages , languages ...
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